• Title/Summary/Keyword: Invasion Detection

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In Vitro imaging of MRI and Ultrasound for Colorectal Carcinoma (직결장암 조직의 자기공명영상과 초음파 소견에 대한 비교 연구)

  • Lee, Hwang Kyu;Jee, Keum Nahn;Hong, Sujin;Koh, Jae Hyang
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.2
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    • pp.133-143
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    • 2013
  • Purpose : To evaluate and compare the accuracy of magnetic resonance imaging (MRI) and ultrasound (US) for detection and estimation of invasion depth of colorectal carcinoma (CRC) by correlation with histopathologic findings in vitro, and to find out the best MR pulse sequence for accurate delineation of tumor from surrounding normal tissue. Materials and Methods: Resected specimens of CRC from 45 patients were examined about tumor detectability and invasion depth of US using high frequency (5-17 MHz) linear transducer in a tube filled with normal saline and MRI in a 8-channel quadrate head coil. The institutional review board approved this study and informed consent was waived. MRI with seven pulse sequences of in- and out-of-phases gradient echo T1 weighted images, fast spin echo T2 weighted image and its fat suppression image, fast imaging employing steady-state acquisition (FIESTA) and its fat suppression image, and diffusion weighted image (DWI) were performed. In each case, both imaging findings of MRI and US were evaluated independently for detection and estimation of invasion depth of tumor by consensus of two radiologists and were compared about diagnostic accuracy according to the histopathologic findings as reference standard. Seven MR pulse sequences were evaluated on the point of accurate delineation of tumor from surrounding normal tissue in each specimen. Results: In specimens of CRC, both imaging modalities of MRI (91.1%) and US (86.7%) showed relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of tumor. In early CRC, diagnostic accuracy of US was 87.5% and that of MRI was 75.0%. There was no statistically significant difference between two imaging modalities (p > 0.05). The best pulse sequence among seven MR sequences for accurate delineation of tumor from surrounding normal tissue in each specimen of CRC was fast spin echo T2 weighted image. Conclusion: MRI and US show relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of resected specimen of CRC. The most excellent pulse sequence of MRI for accurate delineation of tumor from surrounding normal tissue in CRC is fast spin echo T2 weighted image.

Clinical Application of $^{18}F-FDG$ PET in Gastric Cancer (위암에서 $^{18}F-FDG$ PET의 임상 이용)

  • Yun, Mi-Jin;Kim, Tae-Sung;Hwang, Hee-Sung
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.39-45
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    • 2008
  • PET or PET/CT detects only less than 50% of early gastric cancer and 62-98% of advanced gastric cancer. Therefore, mass screening programs are recommended for all adults over the age of 40 for early detection and early treatment of gastric cancer through endoscopy or various radiological tests. The most important step after diagnosis of gastric cancer is accurate staging, which mainly evaluates tumor resectability to avoid unnecessary surgery. Important factors that affect tumor resectability are whether the tumor can be separated from adjacent organs or important blood vessels, the extent of lymph node metastasis, presence of peritoneal metastasis, or distant organ metastasis. To evaluate the extent of local tumor invasion, anatomical imaging that has superior spatial resolution is essential. There are a few studies on prognostic significance of FDG uptake with inconsistent results between them. In spite of lower sensitivity for lymph node staging, the specificity of CT and PET are very high, and the specificity for PET tends to be higher than that for CT. Limited data published so far show that PET seems less useful in the detection of lung and bone metastasis. In the evaluation of pleural or peritoneal metastasis, PET seems very specific but insensitive as well. When FOG uptake of primary tumor is low, distant metastasis also tends to show low FDG uptake reducing its detection on PET. There are only a few data available in the evaluation of recurrence detection and treatment response using FDG PET or PET/CT.

Improvement of Security Management Model for a High Speed Information Network (초고속 정보망의 보안관리모델 개선방안)

  • Seo Jeong-Eun;Kim Yoon-Ho;Choi Se-Ha
    • Journal of The Institute of Information and Telecommunication Facilities Engineering
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    • v.2 no.4
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    • pp.71-77
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    • 2003
  • Security system in internet as well as the performance in information network became more important as the internet environment is getting popular and complicate. In this study, the security system (Firewall and IDS) was installed in high speed information network and analyzed for a change in the speed of data transfer and the possibility of invasion. The selection of appropriate system, efficient detection and protection and surveillance method were suggested and analyzed In order to do experiments, an experimental model was com prized to analyze the parameters that was affected by the detection and protection system in network. This will give a standard how much we can pull up the security system maintaining the network speed.

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Interferon Induced Transmembrane Protein-1 Gene Expression is a Biomarker for Early Detection of Invasive Potential of Oral Squamous Cell Carcinomas

  • Ramanathan, Arvind
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2297-2299
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    • 2016
  • Background: Early detection of malignant transformation with expression biomarkers has significant potential to improve the survival rate of patients as such biomarkers enable prediction of progression and assess sensitivity to chemotherapy. The expression of interferon inducible transmembrane protein 1 (IFITM1) has been associated with early invasion events in several carcinomas, including head and neck cancers, and hence has been proposed as a novel candidate biomarker. As the incidence of oral squamous cell carcinoma (OSCC) is highest in the Indian population, we sought to investigate: 1) the expression pattern of IFITM1 in OSCC tissue samples obtained from Indian patients of Dravidian origin; and 2) the possibility of using IFITM1 expression as a potential biomarker. Materials and Methods: Total RNA extracted from thirty eight OSCC biopsy samples was subjected to semi-quantitative RT-PCR with IFITM1 and GAPDH specific primers. Results: Of the thirty eight OSCC samples that were analyzed, IFITM1 overexpression was identified in fifteen (39%). Seven expressed a low level, while the remainder expressed high level of IFITM1. Conclusions: The overexpression of IFITM1 in OSCC samples indicates that IFITM1 may be explored for the possibility of use as a high confidence diagnostic biomarker in oral cancers. To the best of our knowledge, this is the first time that IFITM1 overexpression is being reported in Indian OSCC samples.

Performance Analysis of Security Management model for Unity Control (통합관제 보안관리모델의 성능분석)

  • 서정은;윤병민;허창우;김윤호
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2003.10a
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    • pp.908-911
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    • 2003
  • In this study, the security system (Firewall and IDS) was installed in high speed information network and analyzed for a change in the speed of data transfer and the possibility of invasion. The selection of appropriate system, efficient detection and protection and surveillance method were suggested and analyzed. In order to do experiments, an experimental model was comprized to analyze the parameters that was affected by the detection and protection system in network. This will give a standard how much we can pull up the security system maintaining the network speed.

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Recent R&D Trends of Anti-Drone Technologies (안티 드론 기술 동향)

  • Choi, S.H.;Chae, J.S.;Cha, J.H.;Ahn, J.Y.
    • Electronics and Telecommunications Trends
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    • v.33 no.3
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    • pp.78-88
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    • 2018
  • As the unmanned aerial vehicle industry and its related technologies grow each year, the number of abuse cases caused by drones is increasing. In addition to the invasion of privacy caused by indiscriminate photography, terrorism using unmanned aerial vehicles, which have a low detection probability, high location accuracy, and the capability of targeting people or places, as well as carrying chemicals, radiation materials, and small bombs, is becoming a significant problem around the world. Accordingly, many companies are developing anti-drone solutions that consist of various technologies such as radar, EO/IR cameras, and RF jammers to detect and disable unmanned aerial vehicles. This article briefly introduces the recent R&D trends and technical levels of anti-drone technologies.

Clinical Features and Treatment of Ocular Toxoplasmosis

  • Park, Young-Hoon;Nam, Ho-Woo
    • Parasites, Hosts and Diseases
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    • v.51 no.4
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    • pp.393-400
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    • 2013
  • Ocular toxoplasmosis is a disease caused by the infection with Toxoplasma gondii through congenital or acquired routes. Once the parasite reaches the retina, it proliferates within host cells followed by rupture of the host cells and invasion into neighboring cells to make primary lesions. Sometimes the restricted parasite by the host immunity in the first scar is activated to infect another lesion nearby the scar. Blurred vision is the main complaint of ocular toxoplasmic patients and can be diagnosed by detection of antibodies or parasite DNA. Ocular toxoplasmosis needs therapy with several combinations of drugs to eliminate the parasite and accompanying inflammation; if not treated it sometimes leads to loss of vision. We describe here clinical features and currently available chemotherapy of ocular toxoplasmosis.

A Bronchogenic Cyst Treated by Mediastinoscopy -A case report- (종격내시경을 이용한 기관지성 낭종절제술 치험 1례)

  • 변정욱;김정철
    • Journal of Chest Surgery
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    • v.29 no.7
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    • pp.789-791
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    • 1996
  • Medstinoscopy has been used in the diagnosis for detection of mediastinal Iymph nodes invasion by bronchogenic carcinoma and metastatic cancer. A 19-year-old male complained of chest disconyortness and dysphagia. A chest roentgenogram showed. the right paratracheal mass. Computed topography findings were consistent with a diagnosis of bronchogenic cyst, and excision of cyst was accomplished via the mediastinoscopy thus avoiding thoracotomy.

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Invasive cervical resorption: treatment challenges

  • Kim, Yookyung;Lee, Chan-Young;Kim, Euiseong;Roh, Byoung-Duck
    • Restorative Dentistry and Endodontics
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    • v.37 no.4
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    • pp.228-231
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    • 2012
  • Invasive cervical resorption is a relatively uncommon form of external root resorption. It is characterized by invasion of cervical region of the root by fibrovascular tissue derived from the periodontal ligament. This case presents an invasive cervical resorption occurring in maxillary lateral incisor, following damage in cervical cementum from avulsion and intracoronal bleaching procedure. Flap reflection, debridement and restoration with glass ionomer cement were performed in an attempt to repair the defect. But after 2 mon, more resorption extended apically. Considering root stability and recurrence potential, we decided to extract the tooth. Invasive cervical resorption in advanced stages may present great challenges for clinicians. Therefore, prevention and early detection must be stressed when dealing with patients presenting history of potential predisposing factors.

A study of object trace using sensor information (센서 정보를 이용한 객체 추적에 대한 연구)

  • Kim, Kwan-Joong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.4
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    • pp.1921-1925
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    • 2013
  • In this paper, we propose a method of object trace to real image object which enter into an area. The trace to a recognized object can be implemented to detect the moving pattern if the object enter into an area. Such as this mechanism can be applied to some applications to danger area or limited area where the invasion of unauthorized object or the moving pattern of an object is identified to achieve the trace and detection of an object.