• 제목/요약/키워드: Internal Layer

검색결과 934건 처리시간 0.028초

Polysaccharide-based superhydrophilic coatings with antibacterial and anti-inflammatory agent-delivering capabilities for ophthalmic applications

  • Park, Sohyeon;Park, Joohee;Heo, Jiwoong;Lee, Sang-Eun;Shin, Jong-Wook;Chang, Minwook;Hong, Jinkee
    • Journal of Industrial and Engineering Chemistry
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    • 제68권
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    • pp.229-237
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    • 2018
  • Medical silicone tubes are generally used as implants for the treatment of nasolacrimal duct stenosis. However, side effects such as allergic reactions and bacterial infections have been reported following the silicone tube insertion, which cause surgical failure. These drawbacks can be overcome by modifying the silicone tube surface using a functional coating. Here, we report a biocompatible and superhydrophilic surface coating based on a polysaccharide multilayer nanofilm, which can load and release antibacterial and anti-inflammatory agents. The nanofilm is composed of carboxymethylcellulose (CMC) and chitosan (CHI), and fabricated by layer-by-layer (LbL) assembly. The LbL-assembled CMC/CHI multilayer films exhibited superhydrophilic properties, owing to the rough and porous structure obtained by a crosslinking process. The surface coated with the superhydrophilic CMC/CHI multilayer film initially exhibited antibacterial activity by preventing the adhesion of bacteria, followed by further enhanced antibacterial effects upon releasing the loaded antibacterial agent. In addition, inflammatory cytokine assays demonstrated the ability of the coating to deliver anti-inflammatory agents. The versatile nanocoating endows the surface with anti-adhesion and drug-delivery capabilities, with potential applications in the biomedical field. Therefore, we attempted to coat the nanofilm on the surface of an ophthalmic silicone tube to produce a multifunctional tube suitable for patient-specific treatment.

CAN 버스 물리 계층에서 해킹된 노드의 대처 기법 (Counterattack Method against Hacked Node in CAN Bus Physical Layer)

  • 강태욱;이종배;이성수
    • 전기전자학회논문지
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    • 제23권4호
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    • pp.1469-1472
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    • 2019
  • 자동차에 사용하는 CAN 버스는 노드에 주소를 부여하지 않기 때문에 여러 노드 중 하나가 해킹을 당하여 악의적인 데이터 프레임을 전송하여도 어느 노드가 해킹 당했는지 식별하기 어렵다. 하지만 이러한 CAN 버스의 내부 공격은 자동차의 안전에 큰 위협이 될 수 있으므로 CAN 버스의 물리 계층에서 신속하게 대처하여야 한다. 본 논문에서는 CAN 버스 상에서 악의적인 데이터 프레임이 감지되면 침입 감지 시스템이 내부 공격 노드의 에러 카운터를 증가시켜서 버스에서 분리시킴으로서 악의적인 공격을 방어하는 기법을 제안하였다. 제안한 기법을 탑재한 CAN 컨트롤러를 Verilog HDL을 이용하여 구현하였고, 이를 통해 제안한 기법이 CAN 버스의 악의적인 내부 공격을 방어할 수 있음을 확인하였다.

2종(種) 대황(大黃)의 외부(外部) 및 내외부형태(內外部形態) (The external and internal morphological standards of original plants and herbal states in two kinds of Rhei Rhizoma)

  • 김자영;최고야;김홍준;주영승
    • 한국한의학연구원논문집
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    • 제12권1호
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    • pp.39-48
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    • 2006
  • The Following is a list of specific external and internal morphology of Rheum palmatum L. and R. undulatum L. in Rhei Rhizoma. 1. For the original plants of Rhei Rhizoma in the literatures. 18 plants are reported. 2. The external characteristics of original plant : R. palmatum has a large palmate leaf, its petiole of radical leaf has a simple bristle and its flower is purple and pink color. Whereas R. undulatum has a medium ovate leaf, its petiole of radical leaf is purphish, its stem leaf surrounds a half of stem and its flower is yellowish white color. 3. The character of herbal states : a. diameter and size-- R. palmaum is bigger and heavier than R. undulatum. b. in section--R. palmatum is dark brown color, R. undulatum is bright brown color Fibrovascular bundle is arranged in circle shape in R. patmatum. R. undulatum shows a distingushed wheel shape. 4. The internal characteristics : R. palmatum has a large intercellular space of cork layer, its cambium is clear and a xylem medullary ray is comparatively tight, Whereas R. undulatum has a tight intercettular space of cork layer., its cambium is a few clear and xylem medullary ray is verty tight. As these results, additional study is required to distinguish herbs and their effect among many kinds of same genus-degree of relatedness.

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이층유체에서 부분 장벽에 의한 표면파와 내부파의 분산 (Surface and Internal Waves Scattering by Partial Barriers in a Two-Layer Fluid)

  • 슈레쉬 쿠마;오영민;조원철
    • 한국해안·해양공학회논문집
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    • 제20권1호
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    • pp.25-33
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    • 2008
  • 파랑은 주로 바람에 의해서 발생하여 많은 에너지를 해안으로 전달하며 각종 수리현상을 야기하고 물질의 이송 등에 의하여 연안환경 뿐만 아니라 인간의 활동에도 큰 영향을 미친다. 또한, 해안 구조물과 파랑의 상호작용에 의한 효과를 정확히 예측하는 것은 구조물의 설계 및 거동특성 파악에 매우 중요하다. 본 논문에서는 이층 유체에서 수표면과 저층에 설치되어 있는 얇은 연직벽에 의한 표면파와 내부파의 분산을 선형파 이론을 이용하여 이차원으로 해석하였다. 반사계수를 계산하여 여러 경우에 대하여 효과를 분석한 결과 반사계수는 구조물의 형상과는 별도로 경계층의 위치와 유체간의 밀도차에 크게 영향을 받는 것으로 밝혀졌다.

Multi-Layer 구조를 사용한 다중 대역 내장형 칩 안테나 (Multi-Band Internal Chip Antenna Using Multi-Layer Substrate for Mobile Handset)

  • 조상혁;조일훈;이인영;표성민;백정우;김영식
    • 한국전자파학회논문지
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    • 제19권7호
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    • pp.778-784
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    • 2008
  • 본 논문에서는 다층 구조를 이 용하여 다중 대 역(GSM, DCS, PCS, WCDMA, 2.3 GHz WiMAX)에서 동작하며, 다층 구조이므로 공간 재활용이 가능하여 안테나 크기를 효율적으로 줄일 수 있는 칩 안테나를 제안하였다. 또한, 중간층에 air-gap을 삽입하여 병렬 캐피시턴스 성분을 감소시켜 넓은 대역폭을 얻을 수 있었다. 제안한 안테나는 RO4003 유전체(${\varepsilon}_r=3.4$)를 사용한 다층 구조의 PIFA이고, 안테나 부피는 $22{\times}5.5{\times}4.0\;mm^3$이다. 측정 결과, 안테나 효율 45 % 이상인 대역폭은 low-band에서 80 MHz($880{\sim}960\;MHz$)이며, high-band에서 690 MHz($1,710{\sim}2,400\;MHz$)을 보였으며, 안테나의 고차 모드와 최상위 층의 공진으로 인해 high-band에서 넓은 대역폭을 갖게 되는 것으로 사료된다.

내부 FC층을 갖는 새로운 CNN 구조의 설계 (Design of new CNN structure with internal FC layer)

  • 박희문;박성찬;황광복;최영규;박진현
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2018년도 춘계학술대회
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    • pp.466-467
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    • 2018
  • 최근 이미지 인식, 영상 인식, 음성 인식, 자연어 처리 등 다양한 분야에 인공지능이 적용되면서 딥러닝(Deep learning) 기술에 관한 관심이 높아지고 있다. 딥러닝 중에서도 가장 대표적인 알고리즘으로 이미지 인식 및 분류에 강점이 있고 각 분야에 많이 쓰이고 있는 CNN(Convolutional Neural Network)에 대한 많은 연구가 진행되고 있다. 본 논문에서는 일반적인 CNN 구조를 변형한 새로운 네트워크 구조를 제안하고자 한다. 일반적인 CNN 구조는 convolution layer, pooling layer, fully-connected layer로 구성된다. 그러므로 본 연구에서는 일반적인 CNN 구조 내부에 FC를 첨가한 새로운 네트워크를 구성하고자 한다. 이러한 변형은 컨볼루션된 이미지에 신경회로망이 갖는 장점인 일반화 기능을 포함시켜 정확도를 올리고자 한다.

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Rendezvous Mission to Apophis: IV. Investigation of the internal structure - A lesson from an analogical asteroid Itokawa

  • Jin, Sunho;Kim, Yaeji;Jo, Hangbin;Yang, Hongu;Kwon, Yuna G.;Ishiguro, Masateru;Jeong, Minsup;Moon, Hong-Kyu;Choi, Young-Jun;Kim, Myung-Jin
    • 천문학회보
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    • 제46권2호
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    • pp.58.1-59
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    • 2021
  • Exploration of asteroids' internal structure is essential for understanding their evolutional history. It also provides a fundamental information about the history of coalescence and collision of the solar system. Among several models of the internal structures, the rubble-pile model, confirmed by the near-Earth asteroid (25143) Itokawa by Hayabusa mission [1], is now widely regarded as the most common to asteroids with size ranging from 200 m to 10 km [2]. On the contrary, monolithic and core-mantle structures are also possible for small asteroids [3]. It is, however, still challenging to look through the interior of a target object using remote-sensing devices. In this presentation, we introduce our ongoing research conducted at Seoul National and propose an idea to infer the internal structure of Apophis using available instruments. Itokawa's research provides an important benchmark for Apophis exploration because both asteroids have similar size and composition [4][5]. We have conducted research on Itokawa's evolution in terms of collision and space weathering. Space weathering is the surface alteration process caused by solar wind implantation and micrometeorite bombardment [6]. Meanwhile, resurfacing via a collision acts as a counter-process of space weathering by exposing fresh materials under the matured layer and lower the overall degree of space weathering. Therefore, the balance of these two processes determine the space weathering degrees of the asteroid. We focus on the impact evidence on the boulder surface and found that space weathering progresses in only 100-10,000 years and modifies the surface optical properties (Jin & Ishiguro, KAS 2020 Fall Meeting). It is important to note that the timescale is significantly shorter than the Itokawa's age, suggesting that the asteroid can be totally processed by space weathering. Accordingly, our result triggers a further discussion about why Itokawa indicates a moderately fresh spectrum (Sq-type denotes less matured than S-type). For example, Itokawa's smooth terrains show a weaker degree of space weathering than other S-type asteroids [7]. We conjecture that the global seismic shaking caused by collisions with >1 mm-sized interplanetary dust particles induces granular convection, which hinders the progression of space weathering [8]. Note that the efficiency of seismic wave propagation is strongly dependent on the internal structure of the asteroid. Finally, we consider possible approaches to investigate Apophis's internal structure. The first idea is studying the space weathering age, as conducted for Itokawa. If Apophis indicates a younger age, the internal structure would have more voids [9]. In addition, the 2029 close encounter with Earth provides a rare natural opportunity to witness the contrast between before and after the event. If the asteroid exhibits a slight change in shape and space weathering degree, one can determine the physical structure of the internal materials (e.g., rubble-pile monolithic, thick or thin regolith layer, the cohesion of the materials). We will also consider a possible science using a seismometer.

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Characteristics of wind loading on internal surface and its effect on wind-induced responses of a super-large natural-draught cooling tower

  • Zou, Yun-feng;Fu, Zheng-yi;He, Xu-hui;Jing, Hai-quan;Li, Ling-yao;Niu, Hua-wei;Chen, Zheng-qing
    • Wind and Structures
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    • 제29권4호
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    • pp.235-246
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    • 2019
  • Wind loading is one of important loadings that should be considered in the design of large hyperbolic natural-draught cooling towers. Both external and internal surfaces of cooling tower are under the action of wind loading for cooling circulating water. In the previous studies, the wind loads on the external surface attracted concernedly attention, while the study on the internal surface was relatively ware. In the present study, the wind pressure on the internal surface of a 220 m high cooling tower is measured through wind tunnel testing, and the effect of ventilation rate of the packing layer on internal pressure is a major concern. The characteristics of internal wind pressure distribution and its effect on wind-induced responses calculated by finite element method are investigated. The results indicate that the wind loading on internal surface of the cooling tower behaves remarkable three-dimensional effect, and the pressure coefficient varies along both of height and circumferential directions. The non-uniformity is particularly strong during the construction stage. Analysis results of the effect of internal pressure on wind-induced responses show that the size and distribution characteristics of internal pressure will have some influence on wind-induced response, however, the outer pressure plays a dominant role in the wind-induced response of cooling tower, and the contribution of internal pressure to the response is small.

D.C magnetron sputter법으로 증착된 TiAlN의 중간층에 따른 특성연구 (Characteristics of TiAlN Film on Different Buffer Layer by D.C Magnetron Sputter)

  • 김명호;이도재;이광민;김운섭;김민기;박범수;양국현
    • 한국재료학회지
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    • 제18권10호
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    • pp.558-563
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    • 2008
  • TiAlN films were deposited on WC-5Co substrates with different buffer layers by D.C. magnetron sputtering. The films were evaluated by microstructural observations and measuring of preferred orientation, hardness value, and adhesion force. As a process variable, various buffer layers were used such as TiAlN single layer, TiAlN/TiAl, TiAlN/TiN and TiAlN/CrN. TiAlN coating layer showed columnar structures which grew up at a right angle to the substrates. The thickness of the TiAlN coating layer was about $1.8{\mu}m$, which was formed for 200 minutes at $300^{\circ}$. XRD analysis showed that the preferred orientation of TiAlN layer with TiN buffer layer was (111) and (200), and the specimens of TiAlN/TiAl, TiAlN/CrN, TiAlN single layer have preferred orientation of (111), respectively. TiAlN single layer and TiAlN/TiAl showed good adhesion properties, showing an over 80N adhesion force, while TiAlN/TiN film showed approximately 13N and the TiAlN/CrN was the worst case, in which the layer was destroyed because of high internal residual stress. The value of micro vickers hardness of the TiAlN single layer, TiAlN/TiAl and TiAlN/TiN layers were 2711, 2548 and 2461 Hv, respectively.

A Case of Human Pulmonary Dirofilariasis in a 48-Year-Old Korean Man

  • Kang, Hyo Jae;Park, Young Sik;Lee, Chang-Hoon;Lee, Sang-Min;Yim, Jae-Joon;Yoo, Chul-Gyu;Kim, Young Whan;Han, Sung Koo;Chai, Jong-Yil;Lee, Jinwoo
    • Parasites, Hosts and Diseases
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    • 제51권5호
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    • pp.569-572
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    • 2013
  • Dirofilariasis is a rare disease in humans. We report here a case of a 48-year-old male who was diagnosed with pulmonary dirofilariasis in Korea. On chest radiographs, a coin lesion of 1 cm in diameter was shown. Although it looked like a benign inflammatory nodule, malignancy could not be excluded. So, the nodule was resected by video-assisted thoracic surgery. Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen. In the center of the necrotic nodules, a degenerating parasitic organism was found. The parasite had prominent internal cuticular ridges and thick cuticle, a well-developed muscle layer, an intestinal tube, and uterine tubules. The parasite was diagnosed as an immature female worm of Dirofilaria immitis. This is the second reported case of human pulmonary dirofilariasis in Korea.