• 한국가구학회지
• /
• 제28권3호
• /
• pp.224-232
• /
• 2017

Building energy saving have been put effort in a long time since buildings consume about 40.6% of total energy use, where heating, cooling and electrical lighting requirement results in energy consumption of building significantly. The window is an important part of building envelope, it usually brings a certain heat load from solar radiation while it allows light passing through, and properly leads to overheating in summer, hence the cooling load increase sand cause of thermal uncomfortable factor. The purpose of this study was to evaluate internal shade performance according to color and materials. There is growing interest in improving the sense of comfort among students who spend most of their time in the classroom. The study examined thermal environment and light environmental performance according to the color and materials of internal blinds to the school classroom. The results of this study were as follows; Among wooden blinds, aluminium blinds, and polyester blinds, the aluminium blinds were most excellent. In addition, among white blinds, light brown blinds, dark brown blinds, the light brown were most excellent.

• Environmental Analysis Health and Toxicology
• /
• 제31권
• /
• pp.1.1-1.13
• /
• 2016

Objectives To investigate the accuracy and scientific validity of the current very low risk factor for hereditary diseases in humans following exposures to ionizing radiation adopted by the United Nations Scientific Committee on the Effects of Atomic Radiation and the International Commission on Radiological Protection. The value is based on experiments on mice due to reportedly absent effects in the Japanese atomic bomb (A-bomb) survivors. Methods To review the published evidence for heritable effects after ionising radiation exposures particularly, but not restricted to, populations exposed to contamination from the Chernobyl accident and from atmospheric nuclear test fallout. To make a compilation of findings about early deaths, congenital malformations, Down's syndrome, cancer and other genetic effects observed in humans after the exposure of the parents. To also examine more closely the evidence from the Japanese A-bomb epidemiology and discuss its scientific validity. Results Nearly all types of hereditary defects were found at doses as low as one to 10 mSv. We discuss the clash between the current risk model and these observations on the basis of biological mechanism and assumptions about linear relationships between dose and effect in neonatal and foetal epidemiology. The evidence supports a dose response relationship which is non-linear and is either biphasic or supralinear (hogs-back) and largely either saturates or falls above 10 mSv. Conclusions We conclude that the current risk model for heritable effects of radiation is unsafe. The dose response relationship is non-linear with the greatest effects at the lowest doses. Using Chernobyl data we derive an excess relative risk for all malformations of 1.0 per 10 mSv cumulative dose. The safety of the Japanese A-bomb epidemiology is argued to be both scientifically and philosophically questionable owing to errors in the choice of control groups, omission of internal exposure effects and assumptions about linear dose response.

• 디지털융복합연구
• /
• 제17권7호
• /
• pp.115-124
• /
• 2019

본 연구는 '중소기업에서 내부 환경요인을 통한 Smart Factory의 핵심요인이 경영성과에 미치는 영향'에 대한 실증연구이다. 연구 목적은 Smart Factory 구축이 경영성과에 영향을 미쳐서 회사가 지속 발전하는데 기여하는지 검증하고, 국가적으로 추진하고 있는 Smart Factory 구축 확대 정책에 대해 제언하고자 한다. 절차는 Smart Factory를 구축한 중소제조기업의 실무자를 중심으로 설문을 받아 SPSS와 SMART PLS로 통계 분석하였다. 연구결과는 첫째, 기업 내부의 환경요인은 Smart Factory 핵심요인에 긍정적인 영향을 미쳤다. 둘째, Smart Factory 핵심요인은 경영성과에 긍정적인 영향을 미쳤다. 위의 입증을 통해서 기업의 환경요인을 고려한 Smart Factory의 핵심요인은 경영성과에 영향을 주는 것으로 나타나, Smart Factory 구축 성과의 이론적인 토대를 마련했다고 할 수 있다. 향후는 Smart Factory 구축방법 연구를 하고자 한다.

• 농업과학연구
• /
• 제47권3호
• /
• pp.485-496
• /
• 2020

Recent changes in the disaster environment have greatly increased the possibility of internal erosion in deteriorated reservoirs; thus, countermeasure methods are required to enhance the drainage performance of embankments. Sand filters have been mainly used to prevent internal erosion; however, due to the sand depletion and environmental problems, new alternative materials are required to replace the sand in the filter zone. In this study, crushed stone was used instead of sand as a material that could satisfy permeability, material supply, demanding conditions, and economic efficiency. Although crushed stone has excellent drainage performance, it has a clogging phenomenon due to its high permeability. Accordingly, the materials need to be separated with a geotextile wrapping method. Additionally, the 3D numerical analysis and a large model experiment were conducted to evaluate the seepage characteristics and in-site application of the crushed stone filter. As a result, the crushed stone filter showed an excellent dispersion effect by reducing the pore water pressure by about 9.5 times that of the sand filter. In addition, it was shown that the safety factor for piping increased significantly by reducing internal erosion. When comparing the economics and supply and demand conditions of the material, crushed stone was evaluated as an effective method to reduce the internal erosion of embankments at deteriorated reservoirs.

• Mycobiology
• /
• 제43권2호
• /
• pp.174-178
• /
• 2015

Fusarium wilt of zucchini in Jeonju, Korea, was first noticed in May 2013. Symptoms included wilting of the foliage, drying and withering of older leaves, and stunting of plants. Infected plants eventually died during growth. Based on morphological characteristics and phylogenetic analyses of the molecular markers (internal transcribed spacer rDNA and translation elongation factor $1{\alpha}$), the fungus was identified as Fusarium oxysporum. Pathogenicity of a representative isolate was demonstrated via artificial inoculation, and it satisfied Koch's postulates. To our knowledge, this is the first report of F. oxysporum causing wilt of zucchini in Korea.

• 한국지반환경공학회 논문집
• /
• 제3권1호
• /
• pp.5-12
• /
• 2002

본 연구에서는 지하수위, 폐기물의 전단강도 정수 그리고 지층 조건이 비위생 매립지 사면의 안정성에 미치는 영향을 검토하였다. 사면의 안정성 해석은 한계평형방법에 근거한 Janbu의 절편법을 사용하였다. 해석 결과 매립지가 완전건조 상태에 있는 경우가 완전포화 상태에 있는 경우에 비해 안전율이 약 2.4~2.8배 정도 증가되었다. 관측된 지하수위 상태 하에서 폐기물의 점착력과 내부마찰각이 증가할수록 사면의 안전율은 선형적으로 증가하였으며, 예상파괴면이 하부지층까지 도달할 경우 하부지층의 조건에 따라 안전율과 예상 파괴면의 형상이 변화한다는 것을 알 수 있었다. 따라서, 폐기물 매립지 건설 시에는 지반조건이 양호한 지반을 선택하고, 지하수위 감소를 위한 차수 및 배수 시스템을 설치하는 것이 사면의 안정성 향상에 도움을 줄 것으로 판단된다.

• Tuberculosis and Respiratory Diseases
• /
• 제78권2호
• /
• pp.99-105
• /
• 2015

Background: Aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor, binds to a wide variety of synthetic and naturally occurring compounds. AhR is involved in the regulation of inflammatory response during acute and chronic respiratory diseases. We investigated whether nuclear receptor coactivator 7 (NCOA7) could regulate transcriptional levels of AhR target genes and inflammatory cytokines in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated human bronchial epithelial cells. This study was based on our previous study that NCOA7 was differentially expressed between normal and chronic obstructive pulmonary disease lung tissues. Methods: BEAS-2B and A549 cells grown under serum-free conditions were treated with or without TCDD (0.15 nM and 6.5 nM) for 24 hours after transfection of pCMV-NCOA7 isoform 4. Expression levels of cytochrome P4501A1 (CYP1A1), IL-6, and IL-8 were measured by quantitative real-time polymerase chain reaction. Results: The transcriptional activities of CYP1A1 and inflammatory cytokines were strongly induced by TCDD treatment in both BEAS-2B and A549 cell lines. The NCOA7 isoform 4 oppositely regulated the transcriptional activities of CYP1A1 and inflammatory cytokines between BEAS-2B and A549 cell lines. Conclusion: Our results suggest that NCOA7 could act as a regulator in the TCDD-AhR signaling pathway with dual roles in normal and abnormal physiological conditions.

• Asian Pacific Journal of Cancer Prevention
• /
• 제17권3호
• /
• pp.993-1001
• /
• 2016

Type 2 diabetes mellitus patients are at increased risk of many forms of malignancies, especially of the pancreas, colon and hepatocellular cancer. Unfortunately, little is known of the possible interaction between antidiabetic drugs and anticancer agents. The present study investigates the influence of metformin (MET) and sitagliptin (SITA) on the in vitro anticancer activity of the microtubule depolymerization inhibitor agent epothilone A (EpoA). Hepatocellular liver carcinoma cell line (HepG2) viability and apoptosis were determined by the MTT test and by double staining with PO-PRO-1 and 7-aminoactinomycin D, respectively, after treatment with EpoA, metformin or sitagliptin. The levels of nuclear factor NF-${\kappa}B$ and p53 were evaluated in the presence and absence of inhibitors. While EpoA and MET inhibited HepG2 cell proliferation, SITA did not. EpoA and SITA induced higher p53 levels than MET. All tested drugs increased the level of NF-${\kappa}B$. Only MET enhanced the proapoptotic effect of EpoA. The EpoA+MET combination evoked the highest cytotoxic effect on HepG2 cells and led to apoptosis independent of p53, decreasing the level of NF-${\kappa}B$. These findings support the link between NF-${\kappa}B$ and p53 in the modulation of apoptotic effects in HepG2 cells treated by EpoA. Our studies indicate that the combination of EpoA and MET applied in subtoxic doses has a stronger cytotoxic effect on liver cancer cells than each of the compounds alone. The therapeutic advantages of the combination of EpoA with MET may be valuable in the treatment of patients with diabetes mellitus type 2 (T2DM) and liver cancer.

• 산업경영시스템학회지
• /
• 제46권1호
• /
• pp.1-14
• /
• 2023

This study is a leading case of empirical analysis of whether, when corporate stakeholders (government, investors, customers, managers, employees) put pressure on companies for ESG management, it affects the introduction and implementation of ESG activities (environmental, social, governance) and affects business performance. As for the research method, a sustainability report was published, and a web survey of Korea Research Inc. was conducted from May 10 to May 20, 2022 targeting ESG management managers of 192 companies, and analyzed through the PLS structural equation model. As a result of the study, it was found that the introduction and execution of ESG is closely influenced by the pressure from the government, investors, managers, and employees, and in particular, the internal pressure of current managers and executives and employees has a great impact on the introduction and implementation of environmental, social, and governance activities. In particular, although external pressure also has some influence, it is practical to suggest that strong internal pressure is necessary for continuous activities and performance. And, methodologically, the main activity indicators of the GRI Reporting Guidelines, which are the most representative ESG management indicators, were developed as a questionnaire, and reliability, validity, and model fit were secured through comparison with indicators of multiple systems and expert reviews. The limitations of this study are that more in-depth analysis by industry or size is possible when ESG management is mature and sufficient samples are secured, and complex ESG pressure factor modeling is possible when more diverse stakeholders are added.

• 대한설비관리학회지
• /
• 제23권4호
• /
• pp.5-19
• /
• 2018

Recently, utilizing the supply chain among companies, major companies support their sub-vendors to establish an environmental management system and transfer the clean production technology(know-how) to them for strengthening of environmental competitiveness. Thus, Green Supply Chain Management(GSCM) became a key successful factor for companies to be environmentally sustainable. This research endeavors to identify the relationship among the inside and outside GSCM implementation activities of Korean manufacturing companies and their financial, operational and environmental performances. Based on a the review of previous research findings, twenty one hypotheses are developed and examined. Total 251 valid responses from 1,634 survey responses are identified and the structural equation models(SEM) are developed and analysed for examining our hypotheses. The result shows that inside GSCM has a positive effect on outside GSCM. Also, it reveals that companies' performances are more positively affected by inside GSCM than by outside GSCM.