• Journal of the Korean Magnetic Resonance Society
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• v.19 no.3
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• pp.99-105
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• 2015

Hsp33 is a prokaryotic molecular chaperon that exerts a holdase activity upon response to an oxidative stress at raised temperature. In particular, intramolecular disulfide bond formation between the four conserved cysteines that bind a zinc ion in reduced state is known to be critically associated with the redox sensing. Here we report the backbone NMR assignment results of the half-oxidized Hsp33, where only two of the four cysteines form an intramolecular disulfide bond. Almost all of the resolved peaks could be unambiguously assigned, although the total assignments extent reached just about 50%. Majority of the missing assignments could be attributed to a significant spectral collapse, largely due to the oxidation-induced unfolding of the C-terminal redox-switch domain. These results support two previous suggestions: conformational change in the first oxidation step is localized mainly in the C-terminal zinc-binding domain, and the half-oxidized form would be still inactive. However, some additional regions appeared to be potentially changed from the reduced state, which suggest that the half-oxidized conformation would be an intermediate state that is more labile to heat and/or further oxidation.

• Membrane Journal
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• v.28 no.4
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• pp.286-295
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• 2018

A novel multi-valent salt based on polyethyleneimine having molecular weight of 800 (PEI 800) has been synthesized and characterized as forward osmosis draws solute. A reaction intermediate was synthesized by the neutralization reaction of polyethyleneimine and methyl acrylate, and was hydrolyzed with potassium hydroxide to synthesize a water soluble carboxylic acid (potassium salt) polyethyleneimine. NMR spectrometry, viscometry measurements and osmometry measurements was performed to characterize the draw solute. Forward osmosis experiments were done to know whether the solute could be used as a draw solute or not. The result shows comparable water flux and lower reverse salt flux compared with NaCl as a draw solute. We have also demonstrated recycling of the draw solute in the FO-NF integrated process.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.3 no.4
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• pp.279-291
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• 2005

To support the design concept and the performance assessment of the cover system for low- and intermediate-level radioactive waste(LILW) disposal facility, a pioneering study is conducted for the tomb of historical age. Research status of the art are investigated and the characteristics of tomb cover are summarized based on the preservation status of historical remains. On-site soil samples are prepared and their unsaturated hydraulic conductivities are measured by an one-step outflow method. Visiting the excavation site of historical tomb and communication with Korean archeological society are required for the further understanding and for the extension to the radioactive waste disposal research.

• Tunnel and Underground Space
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• v.23 no.2
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• pp.99-109
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• 2013

The slopes of open-pit mine are typically designed without considering the reinforcement and support method due to the economical efficiency. However, the long-term stability of final pit slope is needed in some case, therefore the appropriate measures that can improve the stability are required. In this study, the field survey and laboratory test were carried out in S limestone mine. The stability assessment of final pit slope was performed through the stereographic projection method, SMR, and numerical analysis. And countermeasures for stabilization were proposed. The results of analysis show that full scale of slope failure is not expected but the failures of bench slope scale are likely to occur. In oder to increase the stability of bench slope, we suggested the remedial methods as follows: excavating the final pit slope by pre-splitting blasting, placing the wide berm in the intermediate bench slope and installing the horizontal drainage hole in the place of local ground water runoff.

• Membrane Journal
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• v.22 no.6
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• pp.424-434
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• 2012

In this study, a ceramic membrane was prepared by CVD. Tube type alpha alumina support was used for substrate and added the Ga salt in intermediate layer. Synthesized method was counter diffusion CVD method at $650^{\circ}C$ with tetramethylorthosilane (TMOS). Gas permeation was measured at $600^{\circ}C$ using single-component $H_2$, $N_2$, $CO_2$ and $CH_4$. During the steam treatment, $H_2/N_2$ permselectivity of non-Ga silica membrane was decreased 926 to 829 at $600^{\circ}C$. On the other hand $H_2/N_2$ permselectivity of added Ga silica membrane was stable 910 to 904 at $600^{\circ}C$. These results show that the metal-doped membranes improved steam stability for gas separation.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.06a
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• pp.221-230
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• 2005

To support the design concept and performance evaluation of the cover system for low- and intermediate-level radioactive waste(LILW) disposal facility, the pioneering study is conducted with the tomb of historical age. Research status of the art are followed and the characteristics of tomb cover are summarized based on the preservation of historical remains. Visiting the excavation site of historical tomb and communication with Korean archeological society is required for the further understanding and for the extension of radioactive waste disposal research.

• Health Policy and Management
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• v.11 no.4
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• pp.54-69
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• 2001

This study was conducted to assess factors associated with the degree of performance of qualify improvement(QI) activities. A mailed questionnaire survey was conducted between September 15 and October 30, 2000, with the staffs being charge of QI at each of the hospitals with 400 beds or greater. Of the 108 hospitals eligible for inclusion in our study, 79 participated, yielding a response rate of 73.1%. After excluding 12 hospitals that did not perform any QI activities, 117 responses from 67 hospitals were used for the analysis. Using the Malcolm Baldrige National Quality Award Criteria(MBNQAC), perceived performance of QI was measured in terms of the improvement of the quality of clinical practice, clinical supporting department, administrative procedure of receiving care, customer satisfaction, efficiency and standardization of work process. Factors evaluated for the association were the extent of QI implementation, compliance to 5 QI principles, participation of hospital CEOs, budget allocation, history of QI, and bed size. Path analysis was performed to assess the relationship between QI performance and these factors. Major findings of this study are as follows. Hospitals showing higher degree of QI implementation (path coefficient=0.5967, p<0.001)) and better compliance with the basic principes of QI(0.5736, p<0.05) tended to achieve better performance. Path analysis results showed that interest and participation of hospital CEOs(0.1954, p<0.05) and compliance with the basic principes of QI(0.4028, p<0.0001) indirectly affected the outcomes of QI by influencing the intermediate variable of the level of QI implementation. This study results suggest that having employees have a good orientation of the basic concept and principes of QI through relevant training be the most important requirement to achieve better outcomes from QI activities. In addition, to educate leaders of hospitals the need of active implementation of QI is important to encourage their participation and draw strong support for QI programs.

• The Journal of the Korea Contents Association
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• v.15 no.5
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• pp.630-638
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• 2015

This study examines university students' reading strategies based on English proficiency and reading anxiety. A total of 86 university students participated in the study and completed two questionnaires related to reading strategies[9] and reading anxiety[10]. The collected data was quantitatively analyzed using SPSS 21. The results indicated that advanced and intermediate students preferred to use Problem Solving Strategies(PROB), whereas beginning level readers tended to use and Global Reading strategies(GLOB). There was no significant relationship between reading anxiety and reading strategies. However, there were some differences between two groups. High anxiety students preferred to use reading materials and textual clues and try to focus on their reading when they have a difficulty. Low anxiety students tended to adjust reading pace and try to focus on comprehension and reread when they lost their focus. Based on the results of the study, several implications and limitations were discussed.

• Korean Journal of Occupational Health Nursing
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• v.22 no.1
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• pp.35-46
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• 2013

Purpose: The study aimed to identify influencing factors associated with the organizational commitment (OC) among hospital nurses. Methods: A descriptive correlational design was utilized. The subjects of this study were 447 female nurses working for over 6 months in Seoul. The study was based on the data from a self-reported survey using structured questionnaires. The data were collected from September 10 to 30, 2009 and analyzed using Pearson's correlation coefficients and stepwise multiple regression analysis. Results: The mean score of the OC was 2.45, slightly higher than the intermediate level. The mean score of the three-dimensional domain among the OC, affective commitment (AC) was 2.50, continuance commitment (CC) was 2.59, and normative commitment (NC) was 2.29. The influencing factors of nurses' AC were perceived organizational support (POS) (${\beta}$=.31, p<.001), supervisory trust, job burnout, nursing professionalism, and age, which accounted for 49.7%. The influencing factors of the CC were supervisory trust (${\beta}$=.20, p<.001), POS, and job burnout whereas the influencing factors of the NC were POS (${\beta}$=.40, p<.001), supervisory trust, nursing professionalism, and job burnout. Conclusion: It is necessary to develop supportive strategies that increase OC, which also improve the POS, nursing professionalism, and supervisory trust, and alleviate job burnout in hospital nurses.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.20 no.6
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• pp.699-708
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• 2007

Reinforced concrete deep beams are general structural members used as transfer-girder, pile cap, foundation wall and so on. They have a complex stess formation. Generally, failure mechanisms differ from either continuous deep beams or simple supported deep beams. In continuous deep beams, a negative moment is occurred over intermediate support and the location of maximum moment coincide with high shear force. Therefore, failure usually occurs at this region. While on the other hand, in simple supported deep beam, the region of high shear coincides with the region of low moment. The web opening of deep beams for accepting a facility makes shear behaviors of deep beams more complex and gives rise to an expansion of crack around the opening and a decline of shear capacity of deep beams. Therefore, Engineers must determine a delicate reinforcement method to control a crack and increase a shear capacity. The purpose of this report is a computation of an effective reinforcement method through non-linear finite element method by means of adopting various reinforcement method as variables and a computation of shear capacity formula taking an effectiveness of reinforcement into consideration.