• Journal of Korean Tunnelling and Underground Space Association
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• v.16 no.2
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• pp.117-124
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• 2014

The interest in the use of shield TBM (Tunnel Boring Machine) on the tunnel excavation has been increased rapidly in Korea. The shield TBM tunnel is generally designed as non-drainage tunnel. Consequently, if water leakage through the segment joints happens, big problems on the usage and stability of tunnel can be occurred. In this study, the variation of waterproof capacity of hydrophilic waterstop by the construction error and excessive displacement of segment was studied firstly. Secondly, the decrease of durability of hydrophilic waterstop by the sulphate and chloride contained in the groundwater and seawater was investigated. The results showed that if the angle discordance at the segment joints is beyond the 2 degree, the proper waterproof capacity of hydrophilic waterstop can not be guaranteed. In addition, if the hydrophilic rubber waterstop is exposed to the sulphate for a while, the proper durability of hydrophilic waterstop can not be expected.

• Journal of Korean Tunnelling and Underground Space Association
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• v.22 no.1
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• pp.47-58
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• 2020

The interest in the use of shield TBM (Tunnel Boring Machine) on the tunnel excavation has been increased rapidly in Korea. The shield TBM tunnel is generally designed as non-drainage tunnel. Consequently, if water leakage through the segment joints happens, big problems on the usage and stability of tunnel can be occurred. In this study, the variation of waterproof capacity of hydrophilic rubber waterstop by the construction error and excessive displacement of segment was studied. In particular, the waterproof capacity of each of single and double layer arrangements of hydrophilic rubber waterstop was examined to verify the efficiency of the double layer arrangement. The test results show that the single layer and double layer hydrophilic rubber waterstop showed the same waterproof performance. hydrophilic rubber waterstop has favorable on the offset, however unfavorable on the gap.

• Journal of Microbiology and Biotechnology
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• v.26 no.3
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• pp.461-468
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• 2016

In recent years, various naturally occurring defence peptides such as plectasin have attracted considerable research interest because they could serve as alternatives to antibiotics. However, the production of plectasin from natural microorganisms is still not commercially feasible because of its low expression levels and weak stability. A tandemly arrayed plectasin gene (1,002 bp) from Pseudoplectania nigrella was generated using the isoschizomer construction method, and was inserted into the pPICZαA vector and expressed in Pichia pastoris. The selected P. pastoris strain yielded 143 μg/ml recombinant plectasin (Ple) under the control of the methanol-inducible alcohol oxidase 1 (AOX1) promoter. Ple was estimated by SDS-PAGE to be 41 kDa. In vitro studies have shown that Ple efficiently inhibited the growth of several gram-positive bacteria such as Streptococcus suis and Staphylococcus aureus. S. suis is the most sensitive bacterial species to Ple, with a minimum inhibitory concentration (MIC) of 4 μg/ml. Importantly, Ple exhibited resistance to pepsin but it was quite sensitive to trypsin and maintained antimicrobial activity over a wide pH range (pH 2.0 to 10.0). P. pastoris offers an attractive system for the cost-effective production of Ple. The antimicrobial activity of Ple suggested that it could be a potential alternative to antibiotics against S. suis and S. aureus infections.

• Journal of Advanced Navigation Technology
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• v.20 no.6
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• pp.574-579
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• 2016

Unlike general unmanned aerial vehicles, the quad-rotor is attracting the attention of many people because of simple structure and very useful value. However, as the interest in drones increases, the safety and location of vehicles are becoming more important provide against aviation safety accidents or lost accidents. Therefore, in this paper, we propose a tracking system that stabilizes the model with a simple controller by linearized modeling and grasp tilt angle data from various sensor through the filter. The developed tracking system transmits the position of the quad-rotor in flight to the computer and shows it through the route, so it can check the flight path and various information such as flight speed and altitude at the same time. Then the sensor used in the actual quad-rotor can not measure exact sensor data for disturbance and vibration. So we use sensor fusion of Kalman filter and Complementary filter to overcome this problem and the stability of the quad-rotor hovering is realized by PID control. Through simulation, various information such as the speed, position, and altitude of the quad-rotor were confirmed in real time.

• Korean Chemical Engineering Research
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• v.48 no.1
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• pp.1-9
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• 2010

Since carbon dioxide, $CO_2$, was revealed as a major greenhouse gas, techniques for its separation, capture, and storage have received increasing interest in recent years. Aqueous amines are the most widely accepted $CO_2$ absorbents, but they cause the problems such as high regeneration energy, thermal degradation, and loss of absorbents due to their volatility. Ionic liquids having high thermal stability, extremely low vapor pressure, and capability of selectively absorbing specific gases have been proposed as new $CO_2$ capturing solvents which may potentially replace aqueous amines. By reviewing the ionic liquids having capability to absorb $CO_2$ reported in previous papers, we seek to develop a comprehensive understanding on the factors that influence the $CO_2$ solubility in ionic liquids such as their structures, absorption temperature, pressure, water content, etc., and to estimate the potential of ionic liquids as $CO_2$ separating media.

• Archives of Pharmacal Research
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• v.28 no.6
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• pp.736-742
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• 2005

Xyloglucan (XG), which exhibits thermal sol to gel transition, non-toxicity, and low gelation concentration, is of interest in the development of sustained release carriers for drug delivery. Drug-loaded XG beads were prepared by extruding dropwise a dispersion of indomethacin in aqueous XG solution (2 wt.-$\%$) through a syringe into corn oil. Enteric coating of XG bead was performed using Eudragit L 100 to improve the stability of XG bead in gastrointestinal (GI) track and to achieve gastroresistant drug release. Release behavior of indomethacin from XG beads in vitro was investigated as a function of loading content of drug, pH of release medium, and concentration of coating agent. Adhesive force of XG was also measured using the tensile test. Uniform-sized spherical beads with particle diameters ranging from 692 $\pm$ 30 to 819 $\pm$ 50 $\mu$m were obtained. The effect of drug content on the release of indomethacin from XG beads depended on the medium pH. Release of indomethacin from XG beads was retarded by coating with Eudragit and increased rapidly with the change in medium pH from 1.2 to 7.4. Adhesive force of XG was stronger than that of Carbopol 943 P, a well-known commercial mucoadhesive polymer, in wet state. Results indicate the enteric-coated XG beads may be suitable as a carrier for oral drug delivery of irritant drug in the stomach.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.298-298
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• 2006

There has been much interest in incorporating nanoscale voids into dielectric materials in order to reduce their k value, and thus in producing low-k porous interdielectric materials. One approach to the development of low-k dielectric materials is the templated polycondensation of organosilicate precursors in the presence of a thermally labile, organic polymeric porogen. The other is SiOCH films have low dielectric constant as well as good mechanical strength and high thermal stability through PECVD. In this article we explore the nanopore generation mechanism of organosilicate film using star-shape porogen and SiOCH film using bis-trimethylsilylmethane (BTMSM) precursor.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.6
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• pp.27-34
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• 2010

Recently, high-speed railway systems have gained increased interest as a means of environmental friendly transportation, and numerous bridges for high-speed railways have been constructed accordingly. However, bridge design for high-speed railways requires more consideration than conventional railway design because fast-moving trains will lead to significant impact on bridge structures. Thus, this research proposes a revised design considering both bridge-rail longitudinal interaction and dynamic effect of trains to ensure stability of fast travelling trains. To validate the proposed design algorithm, numerical analyses are performed and compared using a constructed 250 m long bridge with 5 spans for a high-speed railway. From the numerical results, the proposed optimum design of high-speed railway bridges exhibits the most economic life-cycle-cost (LCC) when compared with several existing design approaches.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.27 no.1
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• pp.73-86
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• 1997

This study was performed to assess the analyzing methods developed to detect clinically and quantitatively longitudinal bone changes. Through preliminary experiment, accuracy of Cu-Eq value conversion to the mass of HA was examined. For main experiment, 15 intraoral radiograms taken at soon, 1st, 2nd, 4th, and 6th week after implantation of mixture in extracted sites of 3 cases were used. We took the radiograms with copper step wedge as test object and HA phantom X -ray taking was standardized by using Rinn XCP device customized directly to the individual dentition with resin bite block. The images inputted by Quick scanner into computer were digitized and analyzed by NIH image program. The stability of the copper equivalent transformation and the usefulness of two analyzing methods by ROI and Reslice were examined. Obtained results as follows: 1) On the Cu equivalent images, the coefficient of variation in the measurement of Cu-Eq. value of ROI ranged from 0.05 to 0.24 and showed high reproducibility. 2) All results obtained by resliced contiguous image were coincident with those obtained from the assessment by ROI and formation of plot profile. 3) On the stacked and resliced image at the line of interest, we could analyze directly and quantitatively the longitudinal changes at several portions by plot profile and qualitatively by surface plot. 4) Implant area showed marked resorption till 2 weeks after implantation and showed significant increase in Cu-Eq. value at 6th week(p<0.01) and periapical area showed increase in Cu-Eq. value at 6th week compared to after-operation's.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.39 no.4
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• pp.156-160
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• 2013

Objectives: Interest in bone graft material has increased with regard to restoration in cases of bone defect around the implant. Autogenous tooth bone graft material was developed and commercialized in 2008. In this study, we evaluated the results of vertical and horizontal ridge augmentation with autogenous tooth bone graft material. Materials and Methods: This study targeted patients who had vertical or horizontal ridge augmentation using AutoBT from March 2009 to April 2010. We evaluated the age and gender of the subject patients, implant stability, adjunctive surgery, additional bone graft material and barrier membrane, post-operative complication, implant survival rate, and crestal bone loss. Results: We performed vertical and horizontal ridge augmentation using powder- or block-type autogenous tooth bone graft material, and implant placement was performed on nine patients (male: 7, female: 2). The average age of patients was $49.88{\pm}12.98$ years, and the post-operative follow-up period was $35{\pm}5.31$ months. Post-operative complications included wound dehiscence (one case), hematoma (one case), and implant osseointegration failure (one case; survival rate: 96%); however, there were no complications related to bone graft material, such as infection. Average marginal bone loss after one-year loading was $0.12{\pm}0.19$ mm. Therefore, excellent clinical results can be said to have been obtained. Conclusion: Excellent clinical results can be said to have been obtained with vertical and horizontal ridge augmentation using autogenous tooth bone graft material.