• Environmental and Resource Economics Review
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• v.24 no.3
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• pp.523-549
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• 2015

This paper investigates an oil refiner's asymmetric behavior in the adjustments of gasoline and diesel prices to changes in his own price and his rivals' prices as well as input costs. An asymmetric error correction model which allows a firm's pricing behavior to the deviation of other firms' prices from their long-run equilibrium level is employed for estimation using weekly data for the period April 2009 to January 2015. Evidence is found that there is a significant degree of asymmetry in the adjustment of wholesale prices to changes in crude oil price. A similar result in regard to the exchange rate is also found by the data. The estimation results for firm's response to changes in other firms' prices indicates that implicit collusion could be more easily exploited in the wholesale petroleum market as results of firms' interaction with each other and anticipation of rivals' pricing behavior. A few refiners show competitive price adjustment in response to the upward deviation of the others' prices from their equilibrium level.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.2
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• pp.269-281
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• 2018

Unlike its archetype predecessor such as the Highway Capacity Manual of the United States, the Korean Highway Capacity Manual of 2013 provides the analytical models for estimating the saturation flow rates for the lane-occupying work-zones in the proximity of the signalized intersections. Direct application of the revised saturation flow rates into the classic control delay models, however, appears to produce unreasonable delay amount as traffic demand approaches lane-group capacities and surpasses them, which is common phenomena in the work-zones. Complex interaction among vehicles, lane-dropping work-zone geometry and signal operations were never accounted in the traditional control delay models, and considerable differences between the delay model outcomes and field observations are repeatedly experienced. This paper proposes the modified approaches to the delay models in the manual, exerted on all three elements of control delay, and particularly focuses on the temporal and spatial boundary expansion in comparing the simulated results to the estimated ones. Extensive microscopic simulation work and calibration effort supports the modified approaches well enough to use them in the work-zone planning and evaluation.

• Archives of design research
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• v.14
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• pp.141-150
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• 1996

In recent years space planning for modern city has been accomplished through scientific high technique and computer supported collaborative work. Relatively human being is treated as a component of the space or whole building and according to the social structure people tend to prefer private space. The necessity of the open space as an active place is emphasized now because the interaction created between users of the space and the nature, surrounding environment can influence on improving quality of outdoor life and giving the place specific identity. In this paper three ways of analyses of components which compose the open space are studied. Especially through the process of analyses derived from differenet areas, the necessity of communication model in collaborative work is proposed.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 2001.06a
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• pp.149-153
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• 2001

To investigate the mode of bactericidal action for antimicrobial peptide, pediocin, synthetic and mutant pediocins were prepared by direct chemical synthesis. Native pediocin was purified from Pedio-coccus acidilactici M and its conformational structure and bactericidal functions were analyzed and compared to synthetic pediocin. Schematic mode of pediocin actions, how pediocin binds on the target cell membrane, penetrates and makes tunnel are proposed. For these purposes, primary and secondary structures of pediocin was analyzed and disulfide bond assignment was also done. The pediocin purified from P. acidilactici M had high effective bactericidal ability against gram positive bacteria, especially Listeria monocytogenes and was very stable at extreme pHs and even at high temperatures such as autoclaving temperature (121$^{\circ}C$). Pediocin was consisted of 44 amino acids with four cysteines. Novel synthetic peptides were achieved by solid phase peptide synthesis(SPPS) method. To explain the function of cysteine in C-terminal region, mutant pediocin, Ped[C24A＋C44A], was synthesized and their structural and biological functions were analyzed. Second mutant pediocin, Ped[KllE], was prepared to explain the function of lysine at 11 of N-terminal part of pediocin, especially loop of $\beta$-sheet, and to predict the initial binding site of pediocin. The native and synthetic pediocins was showed random coil conformation by spectropolarimetry in moderate conditions. This conformation was observed in extreme conditions such as high temperature and low and high pHs, also. Circular dichroism(CD) data also showed the existence of $\beta$-turn structure in N-terminal part both native and synthetic pediocins. A structural model for pediocin predicts that 18 amino acids in the N-terminal part of the peptide assume a three-strand $\beta$-sheet conformation. This random coil in C-terminal part of pediocin was converted to folding structure, helix structure, in nonpolar solvents such as alcohol and TFE. The disulfide bond between $^{9}$ Cys and $^{14}$ Cys was concrete and inevitable, however, evidences of disulfide bond between $^{24}$ Cys and $^{44}$ Cys was not. Data of Ped[C24A＋C44A], pediocin mutant showed that $^{44}$ Cys was required during killing the target cells but not inevitable, since Ped[C24A＋C44A] still have bactericidal activity but much less than native pediocin. Another pediocin mutant, Ped[KllE], had still bactericidal activity, was controversial to propose that positive charge like as $^{11}$ Lys in loop or hinge in bacteriocin bound or helped to binding to microorganism with electrostatic interaction between cell membrane especially teichoic acid and positive amino acid nonspecifically. The conformation of pediocin among native, synthetic and mutant pediocins did not show big difference. The conformations between oxidized and reduced pediocin were almost similar regardless of native or synthetic.

• International Journal of Highway Engineering
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• v.2 no.1
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• pp.135-145
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• 2000

A new procedure needs to be developed to predict the dynamic layer properties under moving truck loads. In this study, a computer code to evaluate layer moduli of asphalt concrete pavement from measured interior deflections at various depths were developed and verified from numerical model tests. Interior deflections of the pavement are measured from Multi-Depth Deflectometer(MDD). It was found that errors between the given and backcalculated moduli in numerical analysis were less than 0.32% for several numerical models tested. When impact loads were used, a technique to determine the depth to virtual rigid base was proposed through the analysis of compressive wave velocity and impulse loading durations. It was found that errors between the given and backcalculated moduli in numerical analysis were less than 0.114% when virtual rigid base was considered in numerical analysis. The pavement behavior must be evaluated under various vehicle speeds when determining the dynamic interaction between the loading vehicle and pavement system. To evaluate the dynamic behavior on asphalt concrete pavement under various vehicle speeds, truck moving tests were carried out. From the test results with respect to vehicle speed, it was found that the vehicle speed had significant effect on actual response of the pavement system. The lower vehicle speed generates the higher interior deflections, and the lower dynamic modulus.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.1
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• pp.181-197
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• 2013

Objectives : This study aimed to assess the differences in treatment behavior by reviewing data of a medical institution that studies treatment behavior in URI and assessing the treatment efficacy in Korea. Methods : We analyzed the behavior of medical customers and providers of upper respiratory infection medications using the NPS published by the Health Insurance Review Assessment Service. We created an operational definition for complications, and confirmed the difference in complication distribution between medical specialties. We also performed a multivariate analysis using a mixed model to elucidate the factors influencing the occurrence of complications. Results : The outcomes of analyzing factors to influence the difference in practice patterns of the diagnosing URI between the physicians are as follows; (1) Analysis of antibiotics prescriptions rate showed significant difference from medical departments (pediatrics; 49.7%, internal medicine; 54.2%, otorhinolaryngology; 69.6%, family medicine; 61.6%, general surgery; 57.5%, p<0.001). Analysis of steroid prescriptions rate showed significant difference from medical departments (pediatrics; 3.8%, internal medicine; 4.5%, otorhinolaryngology; 5.4%, family medicine; 3.0%, general surgery; 11.2%, p<0.001). (2) In patients who visited medical institutes with the common cold, the complication distribution differed according to the medical specialty, which suggests that specific complications arise depending on the particular medical specialty (p<0.001). (3) Moreover, through multivariate analysis, we found that the complication rate is higher in clinics than in hospitals, depending on the institute's size. (p<0.001; odds ratio of 4.67 in clinics than in hospitals, 95% CI 2.66-8.21) Conclusions : We observe a deviation between the behavior of patients diagnosed with URI and medication providers. This may arise from the interaction between providers and consumers, wherein the complications are associated with the choice of outpatient department and the prevention of cutting incentives. These findings suggest that the health policies should be improved to prevent inappropriate medical practice in the treatment of pediatric URI.

• Journal of the Korean Society of Radiology
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• v.5 no.1
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• pp.11-18
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• 2011

The periosteum contains multipotent cells that can differentiate into osteoblasts and chondrocytes. Cultured periosteum-derived cells (PDCs) have an osteogenic capacity. The purpose of this study was to evaluate the interaction of PDCs with bone graft biomaterial. After cell isolation from the calvarial periosteum of Sprague-Dawley rats, cultured PDCs were placed in critical-sized calvarial defects with beta-tricalcium phosphate (${\beta}$-TCP). All rats were sacrificed 8 weeks after bone graft surgery, and the bone regenerative ability of bone grafting sides was evaluated by plain radiography, micro-computed tomography (CT), and histological examination. PDCs grafted with ${\beta}$-TCP displayed enhanced calcification in the defect site, density of regenerated bone and new bone formation within the defect and its boundaries. Furthermore, these PDCs more efficiently regenerated new bone as compared to grafted ${\beta}$-TCP only. The results suggest that cultured PDCs have the potential to promote osteogenesis in bone defects.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.4
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• pp.457-463
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• 2012

The basilar membrane (BM), one of organs of cochlea, has the specific positions of the maximum amplitude at each of related frequencies. This phenomenon is due to the geometry of BM. In this study, as the part of the research for the development of fully implantable artificial cochlea which is based on polymer membrane, parametric studies are performed to suggest the desirable artificial basilar membrane model which can detect wider range of frequency separation. The vibro-acoustic characteristics of the artificial basilar membrane are predicted through finite element analysis using commercial software Abaqus. Simulation results are verified by comparing with experimental results. Various geometric shapes of the BM and residual stress effects on the BM are investigated through the parametric study to enable a wider detectable frequency separation range.

• Journal of Korea Water Resources Association
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• v.49 no.7
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• pp.635-644
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• 2016

This study investigates variation of flow characteristics due to variation of branch channel width and discharge ratio at bifurcation channel using 2D numerical model. The calculated result considering secondary flow is more accurate and stable than without considering one. The diversion flow rate ($Q_3/Q_1$) is reduced by flow stagnation effect according to the interaction of the secondary flow and flow separation zone in branch channel. The less upstream inflow or the lower upstream velocity, the bigger variation of diversion flow rate by changing branch channel width. At uniform downstream boundary condition, the rate of change in Froude number of downstream of main channel($Fr_2$)-diversion flow rate ($Q_3/Q_1$) relations is similar about -2.4843~-2.6675 when branch channel width ratio (b/B) is decreased. At uniform diversion flow rate ($Q_3/Q_1$) condition, the width of recirculation zone in branch channel is decreased when branch channel width ratio (b/B) is decreased. The less upstream inflow in the case of increasing branch channel width or the narrower branch channel width in the case of increasing upstream inflow, the bigger reduction ratio of recirculation zone width. At uniform inflow discharge ($Q_1$) condition, diversion flow rate, the width and length of recirculation zone in branch channel are decreased when branch channel width ratio (b/B) is decreased.

• Journal of Technology Innovation
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• v.20 no.2
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• pp.161-187
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• 2012

Recently, environmentally friendly technology are becoming important due to reconsideration about climate change and environmental pollution. In addition, as well as technical skills and social interaction through an analysis of the nonlinear transition management and policy implementation are emerging. This study of the development of photovoltaic industry in Korea 10 years analyze with strategic niche management (SNM) based on the theoretical and multi-layered perspective (MLP) is used as the analytical framework. Choose the gerverment-support project for niche technology, through a process of quantifying and alnalyze the phase transition to Regime with the numerical method and policy vision, learning effects, and network that key elements of SNM, MLP. Through the analysis of the photovoltaic industry technology-commercialization phase was investigated. This conventional overall and step-by-step model for technical management is proposed to replace exiting linear and narrow method and through the case study its validity was confirmed.