• Title/Summary/Keyword: Interaction Surface

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Development of Protein Chip for Diagnosis of Chlamydophia Pneumoniae (단백질 칩을 이용한 클라미디아 폐렴의 진단)

  • Kim, Woo Jin;Lee, Hui Young;Lee, Seung-Joon;Jung, Se-Hui;Yuk, Jong Seol;Ha, Kwon-Soo;Jung, Ki-Suck
    • Tuberculosis and Respiratory Diseases
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    • v.60 no.4
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    • pp.412-418
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    • 2006
  • Background; The diagnosis of chlamydial infection is based on serology. The current gold standard of diagnosis is MIF(microimmunofluorescence), but this modality is subjective and time-consuming. Protein microarray with using a SPR(surface plasmon resonance) sensor has recently been suggested as a method for detecting infection. For developing a protein chip to diagnose chlamydial infection, EBs(elementary bodies) were immobilized on a gold chip and the interaction between an antibody for Chlamydophila pneumoniae and the EBs(elementary bodies) immobilized on the surface of the gold chip was measured by using an SPR sensor. Methods; For the surface antigen, the EBs of Chlamydophila pneumoniae LKK1 were purified. Charged arrays were prepared by using PDDA(polydiallyldimethylammonium chloride) which has a positive charge. After immobilization of the chlamydial EBs on the PDDA surface, the investigation of the surface was done with using atomic force microscopy. After the antibody for C. pneumoniae was applied on chip, we monitored the SPR wavelength-shift to detect any antigen-antibody interaction with using a self-assembled SPR sensor. Results; The chlamydial EBs on the positively charged PDDA were visible on the surface with using atomic force microscopy. The SPR wavelength increased after interaction of antibody for C. pneumoniae with the EBs immobilized on charged gold surface. The wavelength-shift was correlated with the concentration of antigens. Conclusion; The surface immobilization of EBs on the gold surface with the charged arrays was identified and the antigen-antibody interaction on the gold chip was detected via the SPR sensor. Further investigations are needed to apply this technique to the clinical field.

About Quiet Pavement Technologies in Korean Highway (국내 고속도로의 저소음포장 기술 동향)

  • Mun, Sung-Ho;Hong, Seung-Ho;Cho, Dea-Seung;Kim, Chul-Hwan
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2008.04a
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    • pp.491-495
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    • 2008
  • The effects of vehicles and pavement surface types on noise have been investigated at the Korea Expressway Corporation's Test Road along the southbound side of the Jungbu Inland Expressway, South Korea. The study was conducted in 2005 and 2006 through field measurements at nine surface sections of asphalt concrete and Portland cement concrete pavements using eleven vehicles. For the road noise analysis, the sound power levels (PWLs) of combined noise (e.g., tire/pavement interaction noise and power-train noise together) and tire/pavement interaction noise using various vehicles were calculated based on the novel close proximity (NCPX) and pass-by methods. Then, the characteristics of the PWLs were evaluated according to surface type, vehicle type, and vehicle speed. The results show that the PWLs of vehicles are diversely affected by vehicle speed and the condition of the road surface.

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INTERACTION OF SURFACE WATER WAVES WITH SMALL BOTTOM UNDULATION ON A SEA-BED

  • Martha, S.C.;Bora, S.N.;Chakrabarti, A.
    • Journal of applied mathematics & informatics
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    • v.27 no.5_6
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    • pp.1017-1031
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    • 2009
  • The problem of interaction of surface water waves by small undulation at the bottom of a laterally unbounded sea is treated on the basis of linear water wave theory for both normal and oblique incidences. Perturbation analysis is employed to obtain the first order corrections to the reflection and transmission coefficients in terms of integrals involving the shape function c(x) representing the bottom undulation. Fourier transform method and residue theorem are applied to obtain these coefficients. As an example, a patch of sinusoidal ripples is considered in both the cases as the shape function. The principal conclusion is that the reflection coefficient is oscillatory in the ratio of twice the surface wave number to the wave number of the ripples. In particular, there is a Bragg resonance between the surface waves and the ripples, which is associated with high reflection of incident wave energy. The theoretical observations are validated computationally.

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Finite Element Analysis for Eddy Current Signal of Aluminum Plate with Surface Breaking Crack (알루미늄 평판의 표면결함에 대한 와전류 신호의 유한요소해석)

  • Lee Joon-Hyun;Lee Bong-Soo;Lee Min-Rae
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.29 no.10 s.241
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    • pp.1336-1343
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    • 2005
  • The detection mechanism of the flaw for the nondestructive testing using eddy current is related to the interaction of the induced eddy currents in the test specimen with flaws and the coupling of these interaction effects with the moving test probe. In this study, the two-dimensional electromagnetic finite element analysis(FEM) fur the eddy current signals of the aluminum plate with different depth of surface cracks is described and the comparison is also made between experimental and predicted signals analyzed by FEM. In addition, the characteristics of attenuation of the eddy current density due to the variation of the depth of a conductor are evaluated. The effective parameters for the application of eddy current technique to evaluate surface cracks are discussed by analyzing the characteristics of the eddy current signals due to the variation of crack depths.

Hydrodynamic analysis of a floating body with an open chamber using a 2D fully nonlinear numerical wave tank

  • Uzair, Ahmed Syed;Koo, Weon-Cheol
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.4 no.3
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    • pp.281-290
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    • 2012
  • Hydrodynamic analysis of a surface-piercing body with an open chamber was performed with incident regular waves and forced-heaving body motions. The floating body was simulated in the time domain using a 2D fully nonlinear numerical wave tank (NWT) technique based on potential theory. This paper focuses on the hydrodynamic behavior of the free surfaces inside the chamber for various input conditions, including a two-input system: both incident wave profiles and forced body velocities were implemented in order to calculate the maximum surface elevations for the respective inputs and evaluate their interactions. An appropriate equivalent linear or quadratic viscous damping coefficient, which was selected from experimental data, was employed on the free surface boundary inside the chamber to account for the viscous energy loss on the system. Then a comprehensive parametric study was performed to investigate the nonlinear behavior of the wave-body interaction.

Improvement of the Wear Resistance of PP using Montmorillonite

  • Kim, Jae June;Ryu, Sung Hun;Oh, Jin Young
    • Elastomers and Composites
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    • v.57 no.2
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    • pp.40-47
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    • 2022
  • The effects of maleic-anhydride-grafted polypropylene (PP-g-MAH) and montmorillonite (MMT) on the wear resistance of polypropylene (PP) were investigated. The surface of MMT was modified with 3-aminopropyltriethoxysilane, and the interfacial interaction between PP and MMT was improved using PP-g-MAH. Fourier-transform infrared spectroscopy was used to confirm that silane was grafted on the surface of MMT. The Taber abrasion test and scanning electron microscopy were used to determine the wear resistance and observe the surface morphology of PP, respectively, after wear testing. Energy-dispersive X-ray spectroscopy was used to compare the effects of PP-g-MAH and silane modification of MMT on the dispersion of MMT. The results indicated that silane was successfully grafted onto the surface of MMT. Moreover, the wear resistance of PP was improved by the addition of MMT. The wear resistance of PP composites comprising silane-modified MMT and PP-g-MAH was higher than those of other PP composites. This was attributed to silane improving the interfacial interaction between MMT and PP.

Mechanical Properties of Acrylonitrile Functionalized Emulsion SBR/silica Compounds (아크릴로니트릴이 극성기로 도입된 유화중합 SBR/실리카 컴파운드의 기계적 물성)

  • Kim, Dong-Won;Seo, Byeong-Ho;Kim, Hee-Jeong;Paik, Hyun-Jong;Kang, Jong-Won;Kim, Won-Ho
    • Elastomers and Composites
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    • v.47 no.1
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    • pp.54-64
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    • 2012
  • Acrylonitrile was introduced in the emulsion SBR to increase compatibility between silica and rubber. AN-SBR/silica compounds showed faster vulcanization time and higher delta torque values than SBR 1721/silica compounds because interaction between nitrile group of AN-SBR and silanol group on the silica surface could make hydrogen bond that prevented adsorption of the accelerator on the silica surface, which improved the vulcanization reaction efficiency and enhanced the degree of crosslinking. AN-SBR/silica compound showed higher values in minimum torque than SBR 1721/silica compound during the vulcanization because AN-SBR has higher molecular weight than SBR 1721 in the raw material. When PEG was added to the SBR 1721 and AN-SBR compounds, vulcanization time was faster than SBR 1721 and AN-SBR compounds without PEG because PEG has a large number of ether linkages which show high compatibility with silanol group on the silica surface that prevented the adsorption of the accelerator and the ingredients on the silica surface, which improved the vulcanization reaction efficiency. In the mechanical properties, AN-SBR compounds showed higher modulus values at 100%, 300% than SBR 1721 compounds because interaction between nitrile group of AN-SBR and silanol group on the silica surface enhanced the degree of crosslinking. In the dynamic properties, AN-SBR compounds showed lower tan ${\delta}$ values at $0^{\circ}C$ than SBR 1721 compounds in accordance with the $T_g$ values. AN-SBR compounds showed lower tan ${\delta}$ values at $60^{\circ}C$ than SBR 1721 compounds because interaction between acrylonitrile and silica caused strong filler-rubber interaction that induced low energy dissipation by the filler-filler interaction.

Interaction between Particle with Dual Ligand and Cell under Flow (유동장내 길이가 다른 두 개의 리간드가 부착된 입자-세포간 상호작용)

  • Yoon, Jung Hyun;Lee, Sei Young
    • Journal of Biomedical Engineering Research
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    • v.43 no.2
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    • pp.71-80
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    • 2022
  • The interaction between dual-ligand decorated particle-based delivery system and target cell under shear flow is predicted using probability model developed. We assumed the two kinds of ligand are decorated on the surface of the particle with 10% length difference. Fixed with other biophysical parameters, a study on the particle-cell interaction for the different non-specific interaction parameter is performed. To induce the firm adhesion, short ligand-receptor should be engaged. Also, it is shown that the rational design of ligand-receptor interaction, including receptor number, specific interaction parameter, kinds of ligand-receptor, etc., should be considered.

Use of Cationic PAM as a Surface Sizing Additive to Improve Paper Properties

  • Seo, Man-Seok;Lee, Hak-Lae;Youn, Hye-Jung
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2006.06b
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    • pp.245-250
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    • 2006
  • This study was focused on the use of cationic PAM (Polyacrylamide) as a surface sizing additive to improve the surface sizing properties of paper. Effects of the ionic property, viscosity and charge density of PAM on bending stiffness of surface sized papers were investigated. Use of cationic PAM as a surface sizing additive improved bending stiffness while addition of anionic PAM did not show any effect. Increase of starch holdout with the addition of cationic PAM was attributed as a prime reason of stiffness increase. Viscosity of PAM was one of the most important factors affecting surface sizing due to its influence on the interaction between cationic PAM and oxidized starch solution. Greater improvement of bending stiffness of paper was obtained when high charged PAM was used as an additive. The order of addition was found to have significant influence on the effect of additives since it influences the formation of network structure among starch, cationic PAM, and SA (styrene acrylic acid copolymer). Investigation on the penetration of starch solution was carried out with CLSM (Confocal Laser Scanning Microscopy), and it was shown that the addition of cationic PAM to oxidized starch solution made starch molecules stay on the paper surface rather than penetrating into the paper structure because of the electrostatic interaction between negatively charged fibers and positively charged cationic PAM.

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Interaction Between an Unstabilized Turbulent Boundary Layer and an Incident Oblique Shock Wave (不安定化된 亂流境界層 과 斜角入射衝擊波 와의 相互作용)

  • 이덕봉
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.9 no.2
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    • pp.158-173
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    • 1985
  • An experimental investigation has been made to study the interaction between and incident oblique shock wave and an unstabilized turbulent boundary layer on a solid surface downstream of a porous surface with air injection through the porous surface. The boundary layer upstream of the interaction is unstabilized by the injection and provokes a shock wave which eventually interacts with the unstabilized boundary layer after reflecting from the upper wall of the test section. Three cases having diferent upstream Mach numbers and different shock strengthes are studied. According to the level of the unstabilization, two cases are of attached boundary layers and the other one is of a separated boundary layer. The result shows that the reflected wavey system is composed of the compression wave, expansion wave fan, and recompression wave like the ordinary interaction while the separated boundary layer strengthens the reflected expansion waves. The interactions of the attached boundary layers show a similar tendency of the upstream wall pressure distribution as that of the ordinary interacton but the pressure rise rather decays in the downstream region. In case of the separated boundary layer, the wall pressure continues to rise in the downstream as opposed ot the former cases. This indicates that the interaction region spreads out widely adn the viscous effect of the separated boundary layer smoothens the abrupt pressure increase due to the shock inpingement.