• Genomics & Informatics
• /
• v.10 no.2
• /
• pp.81-87
• /
• 2012

Large-scale copy number variants (CNVs) in the human provide the raw material for delineating population differences, as natural selection may have affected at least some of the CNVs thus far discovered. Although the examination of relatively large numbers of specific ethnic groups has recently started in regard to inter-ethnic group differences in CNVs, identifying and understanding particular instances of natural selection have not been performed. The traditional $F_{ST}$ measure, obtained from differences in allele frequencies between populations, has been used to identify CNVs loci subject to geographically varying selection. Here, we review advances and the application of multinomial-Dirichlet likelihood methods of inference for identifying genome regions that have been subject to natural selection with the $F_{ST}$ estimates. The contents of presentation are not new; however, this review clarifies how the application of the methods to CNV data, which remains largely unexplored, is possible. A hierarchical Bayesian method, which is implemented via Markov Chain Monte Carlo, estimates locus-specific $F_{ST}$ and can identify outlying CNVs loci with large values of FST. By applying this Bayesian method to the publicly available CNV data, we identified the CNV loci that show signals of natural selection, which may elucidate the genetic basis of human disease and diversity.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.5
• /
• pp.2133-2141
• /
• 2011

The environment of the health food in the world has been changed very rapidly. The world market volume of functional drinks in 2012 will be estimated at $ 26.9 billion, and Asia-Pacific market is expected to be $ 13.6 billion. The domestic market volume of bottled water in 2008 was 440 billion won, and "Jeju Samdasu" sales was 89.1 billion won. But the brand of "Jeju Samdasu" has the limits. As a solution, the comprehensive advertising of the excellence quality of Jeju water is required. To increase the likelihood of success in development of functional and mixed drinks by the water is necessary to develop a global integrated brand. In developing the functional and mixed drinks by the water, we apply the functionality of the Jeju agricultural products actively, and connect Jeju Water industry with Jeju agricultural industry, which promote the overproduction control and the high value- added agricultural products.

• Animal Bioscience
• /
• v.34 no.6
• /
• pp.941-948
• /
• 2021

Objective: In Japan, approximately 50 breeds of indigenous domestic chicken, called Japanese native chickens (JNCs), have been developed. JNCs gradually became established based on three major original groups, "Jidori", "Shoukoku", and "Shamo". Tosa-Jidori is a breed of Jidori, and archival records as well as its morphologically primitive characters suggest an ancient origin. Although Jidori is thought to have been introduced from East Asia, a previous study based on mitochondrial D-loop sequences demonstrated that Tosa-Jidori belongs to haplogroup D, which is abundant in Southeast Asia but rare in other regions, and a Southeast Asian origin for Tosa-Jidori was therefore suggested. The relatively small size of the D-loop region offers limited resolution in comparison with mitogenome phylogeny. This study was conducted to determine the phylogenetic position of the Tosa-Jidori breed based on complete mitochondrial D-loop and mitogenome sequences, and to clarify its evolutionary relationships, possible maternal origin and routes of introduction into Japan. Methods: Maximum likelihood and parsimony trees were based on 133 chickens and consisted of 86 mitogenome sequences as well as 47 D-loop sequences. Results: This is the first report of the complete mitogenome not only for the Tosa-Jidori breed, but also for a member of one of the three major original groups of JNCs. Our phylogenetic analysis based on D-loop and mitogenome sequences suggests that Tosa-Jidori individuals characterized in this study belong to the haplogroup D as well as the sub-haplogroup E1. Conclusion: The sub-haplogroup E1 is relatively common in East Asia, and so although the Southeast Asian origin hypothesis cannot be rejected, East Asia is another possible origin of Tosa-Jidori. This study highlights the complicated origin and breeding history of Tosa-Jidori and other JNC breeds.

• Journal of Advanced Navigation Technology
• /
• v.27 no.3
• /
• pp.247-254
• /
• 2023

GAIN in the US explained in its Pilot/Controller Collaboration Initiatives report that "pilots and air traffic controllers talk to each other all day long, but they rarely communicate." The starting point for the study was the question of whether differences in flight safety perceptions and culture between pilots and air traffic controllers, or other factors, could lead to mutual misunderstandings of procedures and instructions. Digest with The many processes that must be solved within tight deadlines increase the likelihood of accidents through cascading risk factors such as James Reason's Swiss Cheese Theory. Despite the fact that the pilot-air traffic controller complex, which is the subject of flight, occupies a considerable part, there is no integrated management for safe operation between the two groups. Therefore, this research aims to achieve integrated management of safety and education for safe operation between pilots and air traffic controllers through JCRM..

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.5
• /
• pp.3071-3080
• /
• 2015

The increased demand on the transport of both passengers and goods through rail systems implies higher traffic intensity and congestion on the railways, resulting in greater likelihood of accidents and also degraded passenger services. To cope with the issues, development of an integrated communication network for rails has attracted great deal of attention lately. GSM-R is such an example developed in Europe, which seems to have restrictions in providing various communication services due to network speed limit. For the reason, an LTE-based approach is under study in Korea. After the network development, operation management of the network is necessary. Design of operation management systems has been studied little and thus is the objective of this paper. To do so, a conceptual design has been carried out based on model-based approach. Specifically, a context model has first been created using the use case diagram. Then, SysML models of operational scenarios were developed for the management system. The SysML models have alternatively been expressed as EFFBD models to simulate and verify them. Consequently, the result of the conceptual system design for the operation management of the integrated wireless network is expected to be used as a basis for the detailed design later.

• Journal of Navigation and Port Research
• /
• v.34 no.7
• /
• pp.587-594
• /
• 2010

The positive and negative opinion to cargo demand of Incheon's SAMT in the near future remains cloudy. Considering port and shipping environmental changes and the logistics situation of China which explains the lack of facilities in Chinese airports, the creating of SAMT cargoes of the Incheon region could catches a favorable opportunity to be a logistics hub in the North-East Asia. On the other hand, as open-sky policy and direct-call service has been carried out between China and N.A.(North America), Incheon could cause a loss of competitiveness in SAMT because the enhancement in the aspect of the connectivity of Chinese airlines and shipping lines makes customer sent to last destination their cargoes whenever they want. In the same context, this paper analyses on conditions of domestic and international SAMT and proposes in this uncertainty future forecasting of SAMT of Incheon by scenario planning according to changes in integrated SAMT, measuring the likelihood of final scenario. This study shows the Sea & Air multi-transport volume will have either slight increase or decrease from the current condition. Consequently, RFS expansion and system & service improvement through strong ties with major cities in China will be required in a short run aspect. Nonetheless, we also need to take domestic & international transportation environment into account in the long run.

• Journal of Forest and Environmental Science
• /
• v.36 no.1
• /
• pp.7-16
• /
• 2020

Tree size distribution modelling is an integral part of forest management. Most distribution yield systems rely on some flexible probability models. In this study, a simple finite mixture of two components two-parameter Weibull distribution was compared with complex four-parameter distributions in terms of their fitness to predict tree size distribution of teak (Tectona grandis Linn f) plantations. Also, a system of equation was developed using Seemingly Unrelated Regression wherein the size distributions of the stand were predicted. Generalized beta, Johnson's SB, Logit-Logistic and generalized Weibull distributions were the four-parameter distributions considered. The Kolmogorov-Smirnov test and negative log-likelihood value were used to assess the distributions. The results show that the simple finite mixture outperformed the four-parameter distributions especially in stands that are bimodal and heavily skewed. Twelve models were developed in the system of equation-one for predicting mean diameter, seven for predicting percentiles and four for predicting the parameters of the finite mixture distribution. Predictions from the system of equation are reasonable and compare well with observed distributions of the stand. This simplified mixture would allow for wider application in distribution modelling and can also be integrated as component model in stand density management diagram.

• Journal of the Korean Society of Safety
• /
• v.32 no.5
• /
• pp.88-95
• /
• 2017

As the safety fields are expanding to a variety of industrial fields, safety technology has been developed by convergence between industrial safety fields such as mechanics, ergonomics, electronics, chemistry, construction, and information science. As the technology convergence is facilitating recently advanced safety technology, it is important to explore the trends of safety technology for understanding which industrial technologies have been integrated thus far. For studying the trends of technology, the patent is considered one of the useful sources that has provided the ample information of new technology. The patent has been also used to identify the patterns of technology convergence through various quantitative methods. In this respect, this study aims to identify the convergence patterns and fields of safety technology using association rule mining(ARM)-based patent co-classification(co-class) analysis. The patent co-class data is especially useful for constructing convergence network between technological fields. Through linkages between technological fields, the core and hub classes of convergence network are explored to provide insight into the fields of safety technology. As the representative method for analyzing patent co-class network, the ARM is used to find the likelihood of co-occurrence of patent classes and the ARM network is presented to visualize the convergence network of safety technology. As a result, we find three major convergence fields of safety technology: working safety, medical safety, and vehicle safety.

• Journal of Information Technology Services
• /
• v.7 no.3
• /
• pp.1-30
• /
• 2008

This paper proposes an integrated model of customer loyalty in the context of Internet shopping based on a review of two competing perspectives - transactional and relational views. The research model suggests that the usability and trust associated with an Internet shopping site are key determinants of customer loyalty. In this paper, factors such as promotion, ease of use/navigation, and purchase facilitation are posited as major determinants of usability. Trust, on the other hand, is assumed to be influenced by the quality of communication, social shopping service, and safety level associated with an Internet shopping site. This paper also asserts that the lack of consideration for individual differences is one of the key reasons for the inconsistent and mixed research findings in user acceptance literature. In this regard, the elaboration likelihood model (ELM) is considered to be appropriate referent theory as it may theoretically explain why a particular information technology (IT) related message has varying influences on different adopters. The research model comprising 11 hypotheses was derived from and validated through a survey involving 271 university students. The partial least square(PLS) method was used to test the suitability of the research model and its hypotheses. Overall, the results suggest that the usability and trust associated with an Internet shopping site play an important role in acquiring loyal customers. In particular, the user's Internet shopping involvement is found to moderate the relationship between trust and customer loyalty.

• Korean Journal of Agricultural Science
• /
• v.47 no.3
• /
• pp.567-576
• /
• 2020

One of the main challenges receiving much attention in the Rwandan agriculture and food industry in recent decades is the increases in maize prices. Indeed, a rise in maize prices causes higher living expenses for households because maize, which is a major staple food crop, constitutes a significant share of total food consumption among households in Rwanda. The aim of this study was to assess the extent of integration and how prices are transmitted between retail and wholesale markets of domestic maize in Rwanda. This study used monthly data of retail and wholesale prices of maize from January 1995 to December 2019. This empirical investigation was based on a linear cointegration approach and an asymmetric error correction model framework. Using the augmented dickey-fuller residual-based test and the Johansen Maximum Likelihood cointegration test, the results revealed that the retail and wholesale markets of maize are integrated. Hence, prices in these markets do not drift apart in the long run. The results of the Granger causality test revealed that there is a unidirectional causal relationship flowing from wholesale prices to retail prices, i.e., wholesale prices influence retail prices. Accordingly, the results from the asymmetric error correction model confirmed the presence of a positive asymmetric price transmission between wholesale and retail prices of maize in Rwanda. Thus, we suggest that policymakers take a critical look at the causes and factors that may influence asymmetry price transmission.