• The Plant Pathology Journal
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• 제38권5호
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• pp.432-448
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• 2022

Planthopper infestation in rice causes direct and indirect damage through feeding and viral transmission. Host microbes and small RNAs (sRNAs) play essential roles in regulating biological processes, such as metabolism, development, immunity, and stress responses in eukaryotic organisms, including plants and insects. Recently, advanced metagenomic approaches have facilitated investigations on microbial diversity and its function in insects and plants, highlighting the significance of microbiota in sustaining host life and regulating their interactions with the environment. Recent research has also suggested significant roles for sRNA-regulated genes during rice-planthopper interactions. The response and behavior of the rice plant to planthopper feeding are determined by changes in the host transcriptome, which might be regulated by sRNAs. In addition, the roles of microbial symbionts and sRNAs in the host response to viral infection are complex and involve defense-related changes in the host transcriptomic profile. This review reviews the structure and potential functions of microbes and sRNAs in rice and the associated planthopper species. In addition, the involvement of the microbiota and sRNAs in the rice-planthopper-virus interactions during planthopper infestation and viral infection are discussed.

• 한국전자통신학회논문지
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• 제10권4호
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• pp.461-467
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• 2015

119 긴급구조시스템은 화재, 구조, 구급 등 각종 사건사고로부터 인명과 재산을 보호하기 위하여 구축된 소방 신고접수시스템이다. 119 긴급구조시스템을 활용한 상황관제요원들의 사건사고신고 접수능력은 사건사고로부터 소중한 생명과 재산을 보호하고 대처할 수 있는 능력과 직결된다. 119 종합상황실에 투입되는 신규인력과 재배치되는 인력들에 대하여 상황실에서 운용되고 있는 시스템과 동일한 시스템을 이용한 교육훈련이 절실하게 요구되나, 긴급구조시스템은 고가이고 소방본부에서 상시 운용되고 있는 유일한 시스템으로 공동 활용이 불가능하다. 따라서 적은비용으로 다양한 종류의 재해/재난에 대한 사건접수/출동지령/상황관제 등의 훈련을 수행할 수 있는 119 종합상황실 교육훈련시뮬레이터 시스템을 개발하였다.

• 한국전산구조공학회논문집
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• 제16권4호
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• pp.345-351
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• 2003

자동차 산업에서 안전에 대한 법적인 요구 및 시장 수요의 증가에 따라 강도와 경량화라는 안전과 환경에 대한 상반된 목적을 만족시켜야 하기 때문에 일체형 시트의 설계는 점점 더 중요성이 부각되고 있다. 본 연구에서는 미국시험규정 FMVSS210에 따라 외연적 유한 요소해석 프로그램인 LS-Dyna를 사용하여 시트 충돌해석을 수행하였다 하지만 충돌해석은 많은 해석시간을 요구하기 때문에 효율적이고 신뢰성 있는 최적설계기법이 요구된다. 따라서 통계적 기법인 실험계획법과 반응표면모델을 적용하여 많은 해석시간을 요구하는 LS-Dyna해석을 가능한 줄이고 비선형 최적설계 알고리즘을 적용하여 강도와 경량화를 동시에 최적화하고자 한다. 본 연구에서는 실험계획법을 사용하여 최대 변위 및 총중량에 대한 설계영역을 탐색하고 반응표면모델을 구성하여 최적설계를 수행하였다.

• 한국축산식품학회지
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• 제43권4호
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• pp.594-611
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• 2023

Whey protein (WP) has nutritional value, but the presence of β-lactoglobulin (β-LG) and α-lactalbumin (α-LA) cause allergic reactions. In this study, hypoallergenic whey protein hydrolyate (HWPH) was prepared by decomposing β-LG and α-LA of WP using exo- and endo-type proteases. The enzyme mixing ratio and reaction conditions were optimized using response surface methodology (RSM). Degradation of α-LA and β-LG was confirmed through gel electrophoresis, and digestion, and absorption rate, and immunostimulatory response were measured using in vitro and in vivo systems. Through RSM analysis, the optimal hydrolysis conditions for degradation of α-LA and β-LG included a 1:1 mixture of Alcalase and Prozyme reacted for 10 h at a 1.0% enzyme concentration relative to substrate. The molecular weight of HWPH was <5 kDa, and leucine was the prominent free amino acid. Both in vitro and in vivo tests showed that digestibility and intestinal permeability were higher in HWPH than in WP. In BALB/c mice, as compared to WP, HWPH reduced allergic reactions by inducing elevated Type 1/Type 2 helper T cell ratio in the blood, splenocytes, and small intestine. Thus, HWPH may be utilized in a variety of low allergenicity products intended for infants, adults, and the elderly.

• ETRI Journal
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• 제34권3호
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• pp.361-368
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• 2012

A complete high-frequency small-signal circuit model of a 40 Gb/s butterfly electroabsorption modulator integrated laser module is presented for the first time to analyze and optimize its electro-optic (E/O) response and reflection characteristics. An agreement between measured and simulated results demonstrates the accuracy and validity of the procedures. By optimizing the bonding wire length and the impedance of the coplanar waveguide transmission lines, the E/O response increases approximately 5% to 15% from 20 GHz to 33 GHz, while the signal injection efficiency increases from approximately 15% to 25% over 18 GHz to 35 GHz.

• 센서학회지
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• 제24권2호
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• pp.79-82
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• 2015

This paper proposes a novel complementary metal oxide semiconductor (CMOS) active pixel sensor (APS) and presents its performance characteristics. The proposed APS exhibits a linear-logarithmic response, which is simulated using a standard $0.35-{\mu}m$ CMOS process. To maintain high sensitivity and improve the dynamic range (DR) of the proposed APS at low and high-intensity light, respectively, two additional nMOSFETs are integrated into the structure of the proposed APS, along with a photogate. The applied photogate voltage reduces the sensitivity of the proposed APS in the linear response regime. Thus, the conversion gain of the proposed APS changes from high to low owing to the addition of the capacitance of the photogate to that of the sensing node. Under high-intensity light, the integrated MOSFETs serve as voltage-light dependent active loads and are responsible for logarithmic compression. The DR of the proposed APS can be improved on the basis of the logarithmic response. Furthermore, the reference voltages enable the tuning of the sensitivity of the photodetector, as well as the DR of the APS.

• BMB Reports
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• 제54권9호
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• pp.439-450
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• 2021

Translating ribosomes accompany co-translational regulation of nascent polypeptide chains, including subcellular targeting, protein folding, and covalent modifications. Ribosome-associated quality control (RQC) is a co-translational surveillance mechanism triggered by ribosomal collisions, an indication of atypical translation. The ribosome-associated E3 ligase ZNF598 ubiquitinates small subunit proteins at the stalled ribosomes. A series of RQC factors are then recruited to dissociate and triage aberrant translation intermediates. Regulatory ribosomal stalling may occur on endogenous transcripts for quality gene expression, whereas ribosomal collisions are more globally induced by ribotoxic stressors such as translation inhibitors, ribotoxins, and UV radiation. The latter are sensed by ribosome-associated kinases GCN2 and ZAKα, activating integrated stress response (ISR) and ribotoxic stress response (RSR), respectively. Hierarchical crosstalks among RQC, ISR, and RSR pathways are readily detectable since the collided ribosome is their common substrate for activation. Given the strong implications of RQC factors in neuronal physiology and neurological disorders, the interplay between RQC and ribosome-associated stress signaling may sustain proteostasis, adaptively determine cell fate, and contribute to neural pathogenesis. The elucidation of underlying molecular principles in relevant human diseases should thus provide unexplored therapeutic opportunities.

• International Journal of Advanced Culture Technology
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• 제11권4호
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• pp.34-41
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• 2023

The purpose of this paper is to consider the expansion of non-traditional security threats and the national-level response to the emergence of emerging security threats in ultra-uncertain VUCA situations. As a major research method for better analysis, the theoretical approach was referred to papers published in books and academic journals, and technical and current affairs data were studied through the Internet and literature research. The instability and uncertainty of the international order and security environment in the 21st century brought about a change in the security paradigm. Human security emerged as the protection target of security was expanded to individual humans, and emerging security was emerging as the security area expanded. Emerging security threatsthat have different characteristicsfrom traditionalsecurity threats are expressed in various ways, such as cyber threats, new infectious disease threats, terrorist threats, and abnormal climate threats. First, the policy and strategic response to respond to emerging security threats is integrated national crisis management based on artificial intelligence applying the concept of Foresight. Second, it is to establish network-based national crisis management smart governance. Third, it is to maintain the agile resilience of the concept of Agilience. Fourth, an integrated response system that integrates national power elements and national defense elements should be established.

• 정보처리학회논문지A
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• 제15A권1호
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• pp.17-26
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• 2008

본 논문에서는 WSN(wireless sensor networks)과 RFID(radio frequency identification) 시스템을 통합하여 이용할 수 있는 통합 RFID 미들웨어에서의 효과적인 캐슁 기법을 제시한다. 통합 RFID 미들웨어가 운영되는 환경은 연결된 RFID리더로부터 대규모의 데이터가 입력되고, 다수의 무선 센서로부터 끊임없이 데이터가 입력되는 상황을 가정하고 있으며 또한 특정 목적을 위해 과거에 센서로부터 입력되어 분산 저장되어 있는 히스토리 데이터도 활용될 수 있음을 가정하고 있다. 따라서 캐슁 기능을 구비한 특정 미들웨어 레이어에서 센서 노드로부터 수신되는 연속 데이터와 분산 저장되어 있는 히스토리 데이터에 대한 신속한 질의 및 응답을 위한 효율적 데이터 처리가 절실히 요구된다. 이를 위하여 본 논문에서 제안되는 캐슁 기법은 기존의 캐슁 기법 기반으로 통합 RFID 미들웨어에 특화하여 데이터 처리의 효율을 높이기 위하여 두가지 방법을 제시하고 있으며, 이는 처리 데이터의 유형에 따라 DSC(data stream cache)와 HDC(history data cache) 로 구분된다. 제안된 캐슁 기법은 다양한 파라미터를 이용한 실험을 통하여 신속한 질의 및 응답이 이루어짐을 보여주고 있다.

• 한국방재학회 논문집
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• 제9권5호
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• pp.39-46
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• 2009

본 논문은 대규모 재난발생시 재난을 수습하는 재난현장 대응조직인 재난안전대책본부, 긴급구조통제단, 비상지원본부, 현장지휘대(현장지휘소)를 비교분석한 결과, 지역 재난현장 대응조직의 문제점으로 첫째, 재난현장 대응조직간 역할범위가 모호하고, 둘째, 재난대응기관간 조직구조가 다르며, 셋째, 재난현장 대응조직간 총괄 조정기능이 중복되어 있고, 넷째, 총괄지휘권자의 미지정을 지적하였다. 이를 개선하기 위해서는 첫째, 지역 재난현장 대응조직별로 명확한 업무범위 지정과 사전에 재난대응기관간 업무협정을 체결하여야 하고, 둘째, 원활한 의사소통을 위해 재난대응 조직간 동일한 조직구조설계가 필요하며, 셋째, 각 재난현장 대응조직별로 총괄 조정기능 업무를 분담하고, 넷째, 신속한 의사결정을 위하여 재난유형별 재난대응 책임기관과 총괄지휘권자를 미리 지정하여야 할 것이다.