• Genomics & Informatics
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• v.12 no.3
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• pp.98-104
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• 2014

Approximately 45% of the human genome is comprised of transposable elements (TEs). Results from the Human Genome Project have emphasized the biological importance of TEs. Many studies have revealed that TEs are not simply "junk" DNA, but rather, they play various roles in processes, including genome evolution, gene expression regulation, genetic instability, and cancer disposition. The effects of TE insertion in the genome varies from negligible to disease conditions. For the past two decades, many studies have shown that TEs are the causative factors of various genetic disorders and cancer. TEs are a subject of interest worldwide, not only in terms of their clinical aspects but also in basic research, such as evolutionary tracking. Although active TEs contribute to genetic instability and disease states, non-long terminal repeat transposons are well studied, and their roles in these processes have been confirmed. In this review, we will give an overview of the importance of TEs in studying genome evolution and genetic instability, and we suggest that further in-depth studies on the mechanisms related to these phenomena will be useful for both evolutionary tracking and clinical diagnostics.

• Laser Solutions
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• v.12 no.3
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• pp.14-17
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• 2009

The laser welding was performed for the flange joint of two overlapped coaxial circular pipes which serve as the inlet and connector pipes of STS 316L. The laser welding test finally resulted in a good penetration depth of 1.8 to 2.0 mm. On the way to get the good welding quality, two important parameters were found to be optimized. One is the focal positioning which is the offset of the laser beam focus to the exact welding seam line, which is more critical in the inner flange laser welding. When the beam spot size was deviated more than $200\;{\mu}m$ from the seam line, welding of two pipes is failed. The other is a gap size since a certain amount of gap is inevitable due to fabrication tolerance, or artificial allowances for smooth insertion of a pipe. However, it is required to restrict the gap allowance within 0.2mm to avoid undesirable undercut on a welding bead.

• Journal of Biomedical Engineering Research
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• v.26 no.5
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• pp.265-270
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• 2005

A new Computer Integrated Surgical Robot system is composed of a surgical robot, a surgical planning system, and an optical tracking system. The system plays roles of an assisting surgeon and taking the place of surgeons for inserting a pedicle screw in spinal fusion. Compared to pure surgical navigation systems as well as conventional methods for spinal fusion, it is able to achieve better accuracy through compensating for the portending movement of the surgical target area. Furthermore, the robot can position and guide needles, drills, and other surgical instruments or conducts drilling/screwing directly. Preoperatively, the desired entry point, orientation, and depth of surgical tools for pedicle screw insertion are determined by the surgical planning system based on CT/MR images. Intra-operatively, position information on surgical instruments and targeted surgical areas is obtained from the navigation system. Two exemplary experiments employing the developed image-guided surgical robot system are conducted.

• The Journal of the Acoustical Society of Korea
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• v.9 no.3
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• pp.24-30
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• 1990

In this paper, meander line type EMAT(Electro-Magnetic Acoustic Transducer) has been designed and fabricated with effective properties for detecting flaw existing within one wavelength in depth, and its characteristics have been analyzed. For the purpose of getting effective dynamic and static magnetic intensity, the coil has been arrayed using wire with interval of 0.75 mm and width of 0.65 mm and permanent magnets with 1500 Gauss have been constructed respectively. The center frequency and fractional bandwidth of the fabricated EMAT was 2 MHz and 36% respectively and its impulse response has been measured by non-contacting technique(the distance between the conducting media and the coil was 0.15mm). In the measuring results, it has been shown that Insertion Loss(IL) was 45.46dB and it was good agreement with theoretical result.

• Journal of Acupuncture Research
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• v.37 no.4
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• pp.224-232
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• 2020

The purpose of this study was to assess the quality of the case reports in the Journal of Acupuncture Research (JAR). All case reports were retrieved from November 2017 to June 2020. There were 19 case reports included in this assessment based on the case report (CARE) guidelines and case report and standards for reporting interventions in clinical trials of acupuncture (STRICTA) guidelines. The overall quality of reporting was relatively high (83.08% on Case Report guidelines and 77.78% on Standards for Reporting Interventions in Clinical Trials of Acupuncture guidelines), but several crucial items remained substantially underreported, such as identifying as a case report (keywords), patient information and perspective, clinical findings, diagnostic assessment, and intervention information. In 18 out of 19 included case reports of acupuncture-related interventions, several items remained considerably underreported such as acupuncture regimen variation, depth of needle insertion, response sought, and experience of acupuncturists. In the classification by disease, condition, or syndrome, 13 out of 19 included case reports were for musculoskeletal disorders (68.4%), which is the main clinical medical field of Korean medicine services. The results of this study may help develop more appropriate reporting guidelines for case reports published in JAR.

• Nuclear Engineering and Technology
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• v.52 no.7
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• pp.1367-1379
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• 2020

The small modular sodium-cooled fast reactor (SMSFR) is an important component of Generation-IV reactors. The objective of this work is to improve the reactivity control in SMSFR by using innovative systems, including burnable poisons and optimized control rods. SMSFR with MOX fuel usually exhibits high burnup reactivity loss that leads to high excess reactivity and potential fuel melting in control rod withdrawal (CRW) accidents, which becomes an important constraint on the safety and economic efficiency of SMSFR. This work applies two types of burnable poisons in a SMSFR to reduce the excess reactivity. The first one homogenously loads minor actinides in the fuel. The second one combines absorber and moderators in specific assemblies. The influence of burnable poisons on the core characteristics is discussed and integrated into the analysis of CRW accidents. The results show that burnable poisons improve the safety performance of the core in a significant way. Burnable poisons also lessen the demand for the number, absorption ability, and insertion depth of control rods. Two optimized control rod designs with rare earth oxides (Eu₂O₃ and Gd₂O₃) and moderators are compared to the conventional design with natural boron carbide (B₄C). The optimized designs show improved neutronic and safety performance.

• Earthquakes and Structures
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• v.14 no.3
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• pp.241-248
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• 2018

To study the mechanical properties of joints in ancient timber buildings in depth, the force mechanism of the through-tenon joints was analyzed, also the theoretical formulas of the moment-rotation angles of the joints with different loosening degrees were deduced. To validate the rationality of the theoretical calculation formulas, six joint models with 1/3.2 scale ratio, including one intact joint and five loosening joints, were fabricated and tested under cyclic loading. The specimens underwent the elastic stage, the plastic stage and the destructive stage, respectively. At the same time, the moment-rotation backbone curves of the tenon joints with different looseness were obtained, and the theoretical calculation results were validated when compared with the experimental results. The results show that the rotational moment and the initial rotational stiffness of the tenon joints increase gradually with the increase of the friction coefficient. The increase of the tenon section height can effectively improve the bearing capacity of the through-tenon joints. As the friction coefficient of the wood and the insertion length of the tension increase, the embedment length goes up, whereas it decreases with the increase of section height. With the increase of the looseness, the bearing capacity of the joint is reduced gradually.

• Journal of the Korean Chemical Society
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• v.38 no.3
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• pp.194-199
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• 1994

The solubilization sites of some phenyl alkanols such as phenol, benzyl alcohol, phenethyl alcohol, 3-phenyl-1-propanol solubilized in 0.2 M aqueous sodium dodecylsulfate micelle solution was studied by two dimensional heteronuclear correlation spectroscopy (2D C-H COSY). The results show more quantitative and clear solubilization sites in the SDS micelle than previous results using $^1H$-NMR spectrum integration. We found that most of the phenyl alkanols penetrate into the core of SDS micelle, and the insertion depth was 6.5∼7.0 methylene units from ${\alpha}$-methylene.

• Korean Chemical Engineering Research
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• v.54 no.2
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• pp.274-277
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• 2016

Effects of interlayer insertion between multi-quantum well and electron blocking layer of green light emitting diode on diode performances were studied by device simulation. Dependence of Mg doping depth on characteristics of current-voltage, emitting wavelength, leakage current, and external quantum efficiency was investigated, and the optimum diode structure was presented. Device structures with interlayers doped in entire region and up to 30 nm showed remarkable reduced leakage current and effectively relieved efficiency droop which is one of the biggest challenges in green light emitting diode. Furthermore, the most improved characteristics in current-voltage and electroluminescence was obtained by the latter structure.

• The Journal of Korean Medical History
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• v.18 no.1
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• pp.103-126
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• 2005

1) Objective This research is a process of examining the Traditional Acupunctural Methods left in our documents. The objectives of this paper are explaining the process of researching documents and reporting several points revealed in this process. 2) Process This study was done through the following steps: (1) We located the Acupunctural Methods in the original text database on the web. (2) We sorted them according to criterion. (3) We set up some standard clauses in order to organize the selected information. (4) We re-organized the information following the standards within the categories. (5) As for clauses that were not fully explained in the documents, we tried to restore them through other documents. 3) Results (1) 11 standard clauses were set up in order to organize the Traditional Acupunctural Methods. (2) Traditional Acupunctural Methods were extracted from 22 documents, (3) 24 Traditional Acupunctural Methods were extracted and organized by standards. (4) We learned of similar methods with resembling ways of drawing blood and methods with deep interest in the depth of needle insertion. Also, we were able to gain a clue to the exchange of Acupunctural Methods among the three Asian countries and the possibility of research using the Korean Medicine Database.