• Korean Journal of Clinical Laboratory Science
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• v.56 no.1
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• pp.10-20
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• 2024

RNA-sequencing (RNA-seq) is a technique used for providing global patterns of transcriptomes in samples. However, it can only provide the average gene expression across cells and does not address the heterogeneity within the samples. The advances in single-cell RNA sequencing (scRNA-seq) technology have revolutionized our understanding of heterogeneity and the dynamics of gene expression at the single-cell level. For example, scRNA-seq allows us to identify the cell types in complex tissues, which can provide information regarding the alteration of the cell population by perturbations, such as genetic modification. Since its initial introduction, scRNA-seq has rapidly become popular, leading to the development of a huge number of bioinformatic tools. However, the analysis of the big dataset generated from scRNA-seq requires a general understanding of the preprocessing of the dataset and a variety of analytical techniques. Here, we present an overview of the workflow involved in analyzing the scRNA-seq dataset. First, we describe the preprocessing of the dataset, including quality control, normalization, and dimensionality reduction. Then, we introduce the downstream analysis provided with the most commonly used computational packages. This review aims to provide a workflow guideline for new researchers interested in this field.

• Journal of Advanced Technology Convergence
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• v.3 no.3
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• pp.17-27
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• 2024

This study focuses on the development and evaluation of a chatbot system based on the International Classification of Functioning, Disability, and Health (ICF) framework to enhance community participation among elderly individuals with mild dementia in South Korea. The study involved 12 elderly participants who were living alone and had been diagnosed with mild dementia, along with 15 caregivers who were actively involved in their daily care. The development process included a comprehensive needs assessment, system design, content creation, natural language processing using Transformer Attention Algorithm, and usability testing. The chatbot is designed to offer personalized activity recommendations, reminders, and information that support physical, social, and cognitive engagement. Usability testing revealed high levels of user satisfaction and perceived usefulness, with significant improvements in community activities and social interactions. Quantitative analysis showed a 92% increase in weekly community activities and an 84% increase in social interactions. Qualitative feedback highlighted the chatbot's user-friendly interface, relevance of suggested activities, and its role in reducing caregiver burden. The study demonstrates that an ICF-based chatbot system can effectively promote community participation and improve the quality of life for elderly individuals with mild dementia. Future research should focus on refining the system and evaluating its long-term impact.

• The Journal of Korean Society for School & Community Health Education
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• v.25 no.3
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• pp.39-49
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• 2024

Purpose: This study aims to analyze the current status of research related to infants and school-age-child published in the journal of Korean society for school & community health education from 2000 to 2023, with the goal of contributing to the future development and enhancement of the journal. Method: From 2000 to 2023, 52 papers were analyzed, comparing and classifying their journal topic, research types, data collection methods, and data analysis methods. Results: The results shows that the highest publication trend occurred between 2008 and 2012, with most studies focusing on school-age children. In terms of research topic, 'health behavior and health education' was the most frequent with 14 papers (26.9%), followed by oral health with 9 papers (17.3%), safety management with 7 papers (13.5%), and sexual awareness with 6 papers (11.5%). Quantitative research was the most common research type, with surveys being the primary data collection method. Descriptive statistics and t-test were the most frequently used data analysis methods. Conclusion: To enhance the quality of the journal of Korean society for school & community health education, there should be an expansion of evidence-based research focusing on infants and school-age children. Additionally, there is a need for greater diversity in research design, data collection, and analysis methods.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• v.26 no.1
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• pp.1-10
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• 2024

Objective: Endovascular coil embolization is the primary treatment modality for intracranial aneurysms. However, its long-term durability remains of concern, with a considerable proportion of cases requiring aneurysm reopening and retreatment. Therefore, establishing optimal follow-up imaging protocols is necessary to ensure a durable occlusion. This study aimed to develop guidelines for follow-up imaging strategies after endovascular treatment of intracranial aneurysms. Methods: A committee comprising members of the Korean Neuroendovascular Society and other relevant societies was formed. A literature review and analyses of the major published guidelines were conducted to gather evidence. A panel of 40 experts convened to achieve a consensus on the recommendations using the modified Delphi method. Results: The panel members reached the following consensus: 1. Schedule the initial follow-up imaging within 3-6 months of treatment. 2. Noninvasive imaging modalities, such as three-dimensional time-of-flight magnetic resonance angiography (MRA) or contrast-enhanced MRA, are alternatives to digital subtraction angiography (DSA) during the first follow-up. 3. Schedule mid-term follow-up imaging at 1, 2, 4, and 6 years after the initial treatment. 4. If noninvasive imaging reveals unstable changes in the treated aneurysms, DSA should be considered. 5. Consider late-term follow-up imaging every 3-5 years for lifelong monitoring of patients with unstable changes or at high risk of recurrence. Conclusions: The guidelines aim to provide physicians with the information to make informed decisions and provide patients with high-quality care. However, owing to a lack of specific recommendations and scientific data, these guidelines are based on expert consensus and should be considered in conjunction with individual patient characteristics and circumstances.

• The Journal of the Convergence on Culture Technology
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• v.10 no.4
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• pp.121-132
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• 2024

This study attempted to determine the effects of job stress, nursing problem-solving ability, nursing work performance, and job stress and nursing problem-solving ability on nursing work performance according to the MBTI type of nurses. The study subjects were 141 nurses working at a medical institution in G Province, and data collection was conducted from March 01 to March 31, 2024. The collected data were analyzed using correlation and multiple regression analysis. Among the psychological function types of MBTI, the SF type (sympathetic and friendly type) was the most common, and among the psychological temperament types, the SP type (sensuous and open type) was the most common. Nursing work performance had a negative correlation with job resource stress, a positive correlation with nursing problem-solving ability, and a positive correlation with problem recognition, information collection, planning ability, and evaluation. The variable that had a significant impact on nursing work performance was job resources, and problem recognition, a subfactor of nursing problem-solving ability, was found to be the best predictor of nursing work performance, followed by planning ability. The explanatory power was 17.8%. The results of this study are expected to be used as basic data to develop efficient nursing management guidelines by not only improving understanding of the personality of nurses but also investigating factors related to nurses' work performance. Through the development of programs and measures to improve nursing performance, it is necessary to revitalize programs, provide educational opportunities, and provide institutional support from hospital organizations to enable high-quality nursing care through skilled nursing work.

• Journal of The Korean Society of Integrative Medicine
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• v.12 no.3
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• pp.37-47
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• 2024

Purpose : Cancer survivors often suffer from postoperative sequelae. the diagnosing and provision of manual therapy using spiral taping significantly improves the quality of life of cancer patients. The aim of this case study is to investigate the immediate effects of spiral taping on pain, range of motion (ROM), chemotherapy-induced peripheral neuropathy (CIPN), and lymphedema following breast cancer surgery. Methods : The taping techniques were performed as follows by spiral taping. The measurements were taken before, in the middle, and after taping using a mobile phone camera, tape measure, and a numerical rating score (NRS). The evaluation employed a single-group pre-post design based on a primitive experimental design. Results : Out of four patients, all four exhibited Reverse circle flow energy (RCFE), Passive cervical right (Rt) rotation test, anterior-posterior movement pattern, nerve type (+), cold energy (CE), sangcho acupuncture point, blood clot, hwal point. Comparing before and after treatment, almost all values were reduced to zero after treatment in terms of pain complaints. The lack of range of motion (ROM) caused by the shortened tissue after surgery did not increase. The range of motion (ROM) lost due to pain returned to normal. The circumference of lymphedema did not show a tendency. The symptoms of CIPN improved. Conclusion : There was a significant change in joint range of motion, with pain decreasing, but there were structural limitations in the tissue due to total resection, and the chemotherapy-induced peripheral neuropathy scale. It was effectively treated surgical site pain, axillary membrane syndrome-induced pain, and unexplained pain. While there was a treatment effect for lymphedema in the evaluation of circumference values, there was no significant change in circumference. There was a significant effect on chemotherapy-induced peripheral neuropathy, particularly in treating numbness in the feet, which is a side effect of TC anticancer drugs. This case study found that spiral balance taping provides a rapid therapeutic effect for most side effects in patients who have undergone total breast cancer resection. However, the generalization is limited due to the small sample size, and further research is needed to determine the extent to which the effects of one treatment are maintained.

• Journal of the Korean Society of Earth Science Education
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• v.17 no.2
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• pp.181-193
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• 2024

Summative assessment provides information on how well students have achieved learning objectives, making the development of high-quality assessment items essential for accurate evaluation. This is one of the competencies that teachers must possess. This study aims to analyze summative assessment items created by pre-service elementary teachers, examining their intentions and the difficulties encountered in the item development process. The study involved 45 second-year students enrolled in an elementary teacher training university. They were grouped into teams of three and tasked with developing ten items, documenting the purpose of each item, the answer key, and the challenges faced during item creation. The collected summative assessment items were analyzed using a two-dimensional purpose classification table that includes Klopfer's taxonomy of educational objectives. The intentions behind the summative assessments and the difficulties faced during item development were inductively organized and analyzed through qualitative data analysis. The results revealed that pre-service elementary teachers adequately reflected scientific content elements but did not evenly cover assessment domains. The most challenging aspect for them was adjusting the difficulty level. Although they considered most factors that should be taken into account during item development, these considerations were not reflected in the actual items. These findings suggest that knowledge and experience are crucial in developing summative assessment items, and systematic lectures are necessary for pre-service elementary teachers.

• Korean Journal of Culture and Social Issue
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• v.30 no.3
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• pp.267-298
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• 2024

Childcare support for working mothers is crucial for women's smooth transition into society, career development, and well-being. Based on interviews with 10 Korean working mothers with children aged 0-2, this paper explores the process of utilizing childcare support services, psychological experiences, and plans for work-life balance using the grounded theory analysis method. The analysis revealed three categories: the decision-making process before using the childcare services (past), experiences during the use of childcare support (present), and future plans for work-life balance (future). The decision-making process before using childcare support services consisted of the following categories: seeking information about childcare support services, having family discussions during the decision-making process, the proposer and decision-maker of the services, and the final decision on childcare support services. Experiences during the use of services included economic burdens, changes in postnatal career paths, disparities between expectations and the reality of pre- and post-childbirth, discrepancies between expectations and reality in work-family balance, factors affecting of quality of life, and the division of household and childcare responsibilities with husbands. Plans for future work-life balance included categories such as the desire for career advancement, the desire to maintain a career, the desire for temporary or reduced career commitment, and uncertainty regarding future career plans. Finally, the study investigated whether there were differences in the past and present service usage processes and experiences based on plans for future work-life balance. This research suggests the need for multidimensional support for working mothers' work-family balance and well-being, and highlights the need to reduce uncertainty about women's future careers.

• Health Policy and Management
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• v.34 no.3
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• pp.309-318
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• 2024

Background: Sleep disorders in menopausal women can act as a factor that lowers the quality of life. This study aims to understand the effects of mental health, such as depression, generalized anxiety disorder, and stress, on sleep duration in menopausal women to contribute to the management of their mental health. Methods: Using data from the 2021 Korea National Health and Nutrition Examination Survey, we conducted a study on 549 naturally menopausal women aged 50-64 years. We applied frequency and weighted percentages, Rao-Scott chi-square tests, and logistic regression. Results: It was found that women with a university degree or higher had appropriate sleep duration (odds ratio [OR], 0.33; p=0.004). Women with mild depression were less likely to have appropriate sleep compared to those without depression (OR, 2.13; p=0.025). Additionally, women who experienced high levels of stress were less likely to have appropriate sleep compared to those with minimal stress (OR, 2.73; p=0.041). Conclusion: Depression and stress are related to sleep duration, and these mental health issues can lead to physiological problems due to their complex experiences. Therefore, individual attention and management of mental health are crucial, and it seems necessary to develop community-based treatment and prevention strategies.

• Convergence Security Journal
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• v.21 no.4
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• pp.109-115
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• 2021

Currently, with the development of 5G and IoT technology, it is being used in connection with the things used in real life through a network. However, attempts to use networked computers for malicious purposes are increasing, and attacks using malicious codes that infringe the confidentiality and integrity of user information are becoming more intelligent. As a countermeasure to this, research is being conducted on a method of detecting malicious packets using a security control system and AI technology, supervised learning. The cyber security control system is being operated inefficiently in terms of manpower and cost. In addition, in the era of the COVID-19 pandemic, remote work has increased, making it difficult to respond immediately. In addition, malicious code detection using the existing AI technology, supervised learning, does not detect variant malicious code, and has an inaccurate malicious code detection rate depending on the quantity and quality of data. Therefore, in this study, by converging malicious packet detection technologies through various machine learning and deep learning models, the accuracy of malicious packet detection is increased, the false positive rate and the false positive rate are reduced, and a new type of malicious packet can be efficiently detected when intrusion. We propose a malicious packet detection technology.