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Inhibitory Effects of Ethanol Extract from Angelica tenuissima Root on Oxidative Stress and Melanogenesis

  • Koo, Hyun Jung;Lee, Sung Ryul;Park, Yuna;Lee, Jin Woo;So, Gyeongseop;Kim, Sung Hyeok;Ha, Chang Woo;Lee, Sang Eun;Bak, Jong Phil;Ham, Su Ryeon;Lim, Hyosun;Kim, Youn Kyu;Sohn, Eun-Hwa
    • Korean Journal of Plant Resources
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    • v.31 no.4
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    • pp.312-321
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    • 2018
  • Angelica tenuissima, also known as Ligusticum tenuissimum, is classified as a food-related plant and has been used as traditional medicines treating headache and anemia in Asia. However, its anti-melanogenic effect has not been reported in detail. When the extract of Angelica tenuissima (ATE) was prepared by the extraction with 70% EtOH at $80^{\circ}C$ (final yield = 22%), the contents of decursin and Z-ligustilide in ATE were determined 0.06% and 8.43%, respectively. Total flavonoid and phenolic content in mg ATE were $5.52{\pm}0.07{\mu}g$ quercetin equivalents and $237.27{\pm}13.24{\mu}g$ gallic acid equivalents, respectively. Antioxidant capacity of ATE determined by DPPH and ABTS assay was increased with a dose dependent manner up to $1000{\mu}g/m{\ell}$. The amount of melanin synthesis followed by ${\alpha}-melanocyte$ stimulating hormone on B16F10 cells were significantly reduced in the presence of ATE (250 to $1000{\mu}g/m{\ell}$, p<0.05). ATE (125 to $1000{\mu}g/m{\ell}$, p<0.05) suppressed the tyrosinase activity but did not show any significant effect on ${\alpha}-glucosidase$ activity at the same condition. Taken together, ATE possesses tyrosinase inhibitory potential with significant antioxidant capacities. These effects of ATE might be involved in suppression of melanin synthesis, at least, in B16F10 cells. The anti-melanogenic potential of ATE will provide an insight into developing a new skin whitening product.

Basic Study on the Recycling of a Waste MgO-C Refractory Material as a Flux for EAF Steelmaking (전기로 폐 MgO-C계 내화재의 제강원료 활용 가능성 연구)

  • Wang, Jei-Pil;Kim, Hang-Goo;Go, Min-Seok;Lee, Dong-Hun
    • Resources Recycling
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    • v.30 no.6
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    • pp.53-60
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    • 2021
  • In EAF steelmaking industries, MgO content in slag increases due to the addition of dolomite flux to protect refractory lines of furnaces and improve the desulfurization capability of slag. In addition, coal powder is injected in the molten steel bath to increase the energy efficiency of the process. In this regard, the utilization of waste MgO-C refractory material as a flux was examined because it has high amounts of MgO (>70%) and graphite carbon (>10%). A series of experiments were carried out using industrial EAF slag with added light burnt dolomite and waste MgO refractory material from a Korean steel company. The results for the addition of the two fluxes were similar in terms of slag basicity; therefore, it is expected that waste MgO-C refractory material can successfully replace dolomite flux. In addition, when the waste MgO-C refractory material was added as flux, slag foaming phenomenon was demonstrated because of the reaction between the graphite from the refractory material and iron oxides in the slag.

Usability Evaluation of Knitting Customizing Website Using Knitting Machine (니팅머신을 이용한 니트 커스터마이징 웹 사이트 사용성 평가)

  • Jeong, Je-Yoon;Seo, Ji-Young;Lee, Saem;Nam, Won-Suk
    • Journal of the Korea Convergence Society
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    • v.12 no.10
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    • pp.19-25
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    • 2021
  • This study contains the results obtained after two and a half years of developing a knitting customization website using a knitting machine. Recently in the fashion world, various services using customization are being provided, and devices that users can design directly using knitting machines are being developed. However the existing website for knitting machine does not provide a certain usability or layout, so it is difficult for users to use open source and custom design. Therefore, this study was conducted for the purpose of developing a website that provides ease of use to users who will use the knitting customizing service using a knitting machine. As a research method, the first usability evaluation was conducted by synthesizing the studies conducted for the knit customization website development work. As a result of the study, found the problems of the initial custom screen and the initial output screen were found, and convenience, intuition, and readability were improved. Secondary usability evaluation was conducted on the modified website and it was confirmed that the problem was corrected. Through the website finally derived from this study, it is expected that the new platform in the domestic knit market will be popularized and the usability of the custom website will be improved.

The Details and Outlook of Three Data Acts Amendment in South Korea: With a Focus on the Changes of Domestic Financial and Data Industry (데이터 3법 개정안의 내용과 전망: 국내 금융 및 데이터 산업계의 변화를 중심으로)

  • Kim, Eun-Chan;Kim, Eun-Young;Lee, Hyo-Chan;Yoo, Byung-Joon
    • Informatization Policy
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    • v.28 no.3
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    • pp.49-72
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    • 2021
  • This study analyzes the major content, significances, and future outlook of Three Data Acts amendment enacted in August 2020 in South Korea, with the focus on their impact on the financial and data industries. It seems that the revision of the Credit Information Act will enable the specification of a business which had previously only been regulated as the business of credit inquiry, and also enable the domestic data industry to activate the MyData industry, data trading and platforms, and specify data pseudonymization and trading procedures. For the rational and efficient implementation of the amendments to the Three Data Acts, the Personal Information Protection Committee must be as transparent and lawful in its activities as possible, and fairness must be guaranteed. Even in the utilization of personal information, the development or complementation of the related data processing technologies is essential, and clear data processing methods and areas must be regulated. Furthermore, the amendments must be supported with guarantees and the systematization of a fair competitive system in the data market, stricter regulations on penalties for illegal acts related to data, establishment and strengthening of the related security systems, and reinforcement of the system of cooperation for data transfer.

A Study on Colors through Regeneration Design for Abandoned Factory Buildings - The Color of Buildings in the Port Area of Bongnae-dong, Yeongdo, Busan as an Example - (폐공장 건물 재생디자인에 대한 색채 관한 연구 - 부산 영도 봉래동 항만지역 건축물 색채를 중심으로 -)

  • Li, XinTong;Zhang, Ning;Cho, Joung-Hyung
    • Journal of the Korea Convergence Society
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    • v.12 no.10
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    • pp.177-188
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    • 2021
  • In South Korea, with the advancement of the 'Port' project, the regeneration industry adapted to the modern economic development has been promoted, leading to construction around the port was also redefined. Therefore, through regeneration, the problem of image construction of buildings around the port has been re-examined, in which color is an important content of image construction. In this study, the exterior walls of abandoned factory buildings in the port area of Bongnaedong, Pusan were selected as the color research object and evaluated according to the characteristics of the regenerated factory buildings combined with the building color function. Technically, KSCP color analysis system is used for color analysis. In this way, the color plan for the exterior walls of the factory buildings is proposed to visually enhance the image of abandoned factory buildings and attract more attention, thus driving the regional economic development. The results of this study show that in order to adapt to the regional, industrial and commercial characteristics of the regenerated port space, the color hue, lightness, chroma and use area of the building can be changed to enhance the aesthetic value and enhance the inductivity and security.

Thermal Conductivity Enhancement of Polyimide Film Induced from Exfoliated Graphene Prepared by Electrostatic Discharge Method (정전기 방전에 의해 제조된 흑연박리 그래핀 첨가 폴리이미드 막의 열전도 향상)

  • Lim, Chaehun;Kim, Kyung Hoon;An, Donghae;Lee, Young-Seak
    • Applied Chemistry for Engineering
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    • v.32 no.2
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    • pp.143-148
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    • 2021
  • A thermally conductive 200 ㎛ thick polyimide-based film was made from a polyamic acid (PAA) precursor containing graphene prepared from graphite rod using an electrostatic discharge method in order to improve the thermal conductivity and expand the applicability of polyimide (PI) film. Properties of graphene produced by electrostatic discharge were measured by Raman spectroscopy, transmission electron microscopy and X-ray photoelectron spectroscopy (XPS). As a result of Raman spectrum and XPS analyses of as-prepared graphene, the ID/IG ratio was 0.138 and C/O value was 24.91 which are excellent structural and surface chemical properties. Moreover, thermal conductivities of polyimide films increased exponentially according to graphene contents but when the graphene content exceeded 40%, the polyimide film could not maintain its shape. The thermal conductivity of carbonized PI film made from PAA containing 40 wt% of graphene was 51 W/mK which is greatly enhanced from the pristine carbonized PI film (1.9 W/mK). This result could be originated from superior properties of graphene prepared from the electrostatic discharge method.

Quality Characteristics of Fish Paste Prepared with Astragalus membranaceus Powder (황기분말을 첨가한 어묵의 품질특성)

  • Kim, Dong-Ho
    • Food Engineering Progress
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    • v.15 no.4
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    • pp.362-369
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    • 2011
  • This study was conducted to investigate the physicochemical and sensory characteristics of the fish paste prepared with Astragalus membranaceus powder (0-2.0%). The pH of the samples ranged from 6.75 to 6.86 and the moisture content ranged from 77.19 to 80.18%. Increasing amount of Astragalus membranaceus powder in the fish paste tended to increase the redness and yellowness in Hunter color value. Textural property analysis indicated that the strength of the sample paste increased and its springiness decreased with an increasing amount of Astragalus membranaceus powder. The fish paste prepared with Astragalus membranaceus powder (2.0%), especially, showed the highest values in cohesiveness, brittleness, and gumminess. In addition, all the samples had good flexibility. In sensory evaluation, the addition of 1.0% Astragalus membranaceus powder had the best score in color, texture, taste, and overall preference. Therefore, this results suggest that 1.0% Astragalus membranaceus powder can be applied to produce fish paste with high functionality and sensory preference.

Validation of HPLC Methods for Ascorbic Acid and Its Derivatives in Foods (식품 중 아스코르빈산 유래 산화방지제의 HPLC 분석법 검증 및 개선)

  • Jeong, Min Kyu;Park, Chan Uk;Park, Min Hee;Yeo, JuDong;Park, SeungKwan;Kim, SoHee;Shin, Tae-Sun;Baek, Hyung Hee;Lee, JaeHwan
    • Food Engineering Progress
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    • v.15 no.1
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    • pp.75-79
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    • 2011
  • Analytical methods for food antioxidants including ascorbic acid, erythorbic acid, ascorbyl palmitate (AP), and ascorbyl stearate (AS), were validated using high performance liquid chromatography. Validation parameters such as linearity, limit of detection (LOD), limit of quantification (LOQ), and recovery were tested using lard and cider as food model systems. Linearity of ascorbic acid and erythorbic acid were both higher than ($R^2$> 0.99), LOD of these compounds were 0.46 and 0.48 ${\mu}g/mL$, respectively and LOQ were 1.39 and 1.45 ${\mu}g/mL$, respectively. The recovery rates of these compounds were 86.35-94.78% and 84.76-95.02%, respectively. However, the concentration of AP and AS decreased in methanol stock solution. Four other solvents including ethanol, acetonitrile, mixture of methanol and acetonitrile, and mixture of ethanol and acetonitrile were tested to increase the stability of AP and AS under room temperature and refrigerated temperature. Ethanol provided better stability of AP and AS under both room and refrigerated temperature. This study can help to accurately analyze the content of ascorbic acid and its derivatives in processed foods.

Functional Investigation of Ogaza Extract (오가자 추출물의 기능성 검정)

  • Jung, Sung-Keun;Lee, Hyong-Joo
    • Food Engineering Progress
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    • v.14 no.2
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    • pp.183-187
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    • 2010
  • Multiple lines of study have shown that Acanthopanax species have anti-oxidant and chemopreventive effect. However, the suitability of Acanthopanax sessilifloru fruit (Ogaza) as a functional food source remains to be investigated. Therefore, we have investigated the effect of Ogaza as an anti-oxidant and anti-inflammatory substance. The phenolic content of Ogaza is 56.1${\pm}$5.2 mg gallic acid equivalents (GAE) per 1 g of Ogaza. The 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical scavenging effects of Ogaza extract at 0.25, 0.5, 1, or 2 mg/mL were 34.0, 73.0, 194.3, or 339.7 $\mu g$/mL vitamin C equivalent antioxidnat capacity (VCEAC), respectively. Ogaza extract (1 or 2 mg/mL) inhibited LPS-induced TNF-$\alpha$ production (decrease of 22${\pm}$2% or 19${\pm}$6%, respectively). It also inhibited LPS-induced IL-6 production (decrease of 18${\pm}$2% or 24${\pm}$3%, respectively). In addition, Ogaza extract (0.25, 0.5, 1, or 2 mg/mL) inhibited COX-2 luciferase activity (decrease of 80${\pm}$1%, 83.${\pm}$7%, 96${\pm}$4%, or 98${\pm}$2%, respectively). Overall, these results indicated that Ogaza is promising as a functional food source due to its antioxidant and anti-inflammatory effects.

The Optimization of Thermal Conditions and Evaluation of Storage for Heated Chunbok-jang (전복장의 열처리 공정의 최적화 및 저장성 평가에 관한 연구)

  • Moon, Chang-Yong;Baek, Moo-Yeul;Kim, Hae-Kyung;Hahm, Young-Tae;Kim, Byung-Yong
    • Food Engineering Progress
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    • v.15 no.3
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    • pp.230-234
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    • 2011
  • The objective of this study was to optimize the thermal condition and determine the shelf life of heated Chunbokjang product. The optimum thermal condition of heated Chunbok-jang product was determined by sensory test, and heat penetration curve was obtained by Thermal Microprocessor. Sterilization time was a 21~23 min until $F_0$ value reached 9 min, depending upon the number of abalone. As solid content was reduced and temperature of sterilization was increased, the thermal death time was decreased. The score of sensory test indicated that there was no significant difference in flavor of heated Chunbok-jang product made at different sterilization temperatures (110, 121.1, 125, and $130^{\circ}C$). Heated Chunbok-jang product, however, sterilized at $125^{\circ}C$ showed the highest score in texture and taste values. Salinity and pH were not changed during seven month storages, but texture became firmer, and any microorganism had not been detected from the heated chunbok-jang product during these periods. As a result of storage experiment, the shelf-life of heated Chunbok-jang product was 3-month at room temperature.