• Journal of Chest Surgery
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• 제53권1호
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• pp.1-7
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• 2020

Background: The aim of this study was to evaluate the short-term and long-term results of surgical treatment for native valve endocarditis (NVE) and to investigate the risk factors associated with mortality. Methods: Data including patients' characteristics, operative findings, postoperative results, and survival indices were retrospectively obtained from Hallym University Sacred Heart Hospital. Results: A total of 29 patients underwent surgery for NVE (affecting the mitral valve in 20 patients and the aortic valve in 9) between 2003 and 2017. During the follow-up period (median, 46.9 months; interquartile range, 19.1-107.0 months), the 5-year survival rate was 77.2%. In logistic regression analysis, body mass index (p=0.031; odds ratio [OR], 0.574; 95% confidence interval [CI], 0.346-0.951), end-stage renal disease (ESRD) (p=0.026; OR, 24.0; 95% CI, 1.459-394.8), and urgent surgery (p=0.010; OR, 34.5; 95% CI, 2.353-505.7) were significantly associated with in-hospital mortality. Based on Cox proportional hazard regression analysis, the statistically significant predictors of long-term outcomes were hypertension, ESRD, and urgent surgery. Conclusion: Surgical treatment for NVE is associated with considerable mortality. The in-hospital mortality and 5-year survival rates of this study were 13.8% and 77.2%, respectively. Underlying conditions, including hypertension and ESRD, and urgent surgery were independent risk factors for unfavorable outcomes.

• Journal of Welding and Joining
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• 제28권5호
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• pp.75-79
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• 2010

The Remote welding system(RWS) using $CO_2$ laser equipment has focusable distance of laser beam longer than 800 mm from workpiece and can deflect the laser beam by the scanner mirrors very rapidly. In the case of normal welding system based on robot, there is a limit to move the shortest path in short time and this causes interference between robot and workpiece. On the other hand, RWS is the optimized equipment to get big merits with advanced sequence of welding and short cycle time. However, there is still a pending task such as the control of plasma in the welding process of thick sheets therefore, it requires high power laser beam because of the absence of assist gas equipment in itself. In this study, high-tensile steel plates were overlap welded with $CO_2$ RWS for the production of car body and the influence of penetration depth according to the existence of assist gas was analyzed. Excellent tensile strength with enough width of molten zone independent to penetration depth was observed under welding condition with 3.6 kW laser power and 2.8 m/min welding speed without assist gas. Finally, the proto-type automotive parts were produced by applying the deduced optimal welding condition.

• Molecules and Cells
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• 제28권1호
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• pp.13-17
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• 2009

Basic fibroblast growth factor (bFGF) plays an important role in angiogenesis. However, the underlying mechanisms are not clear. $Mg^{2+}$ is the most abundant intracellular divalent cation in the body and plays critical roles in many cell functions. We investigated the effect of bFGF on the intracellular $Mg^{2+}$ concentration ($[Mg^{2+}]_i$) in human umbilical vein endothelial cells (HUVECs). bFGF increased ($[Mg^{2+}]_i$) in a dose-dependent manner, independent of extracellular $Mg^{2+}$. This bFGF-induced $[Mg^{2+}]_i$ increase was blocked by tyrosine kinase inhibitors (tyrphostin A-23 and genistein), phosphatidylinositol 3-kinase (PI3K) inhibitors (wortmannin and LY294002) and a phospholipase $C{\gamma}$ ($PLC{\gamma}$) inhibitor (U73122). In contrast, mitogen-activated protein kinase inhibitors (SB202190 and PD98059) did not affect the bFGF-induced $[Mg^{2+}]_i$ increase. These results suggest that bFGF increases the $[Mg^{2+}]_i$ from the intracellular $Mg^{2+}$ stores through the tyrosine kinase/PI3K/$PLC{\gamma}$-dependent signaling pathways.

• 한국의류산업학회지
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• 제10권6호
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• pp.955-965
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• 2008

This study used the method that measure the participants' responds on the experiment, and the measurement means is a survey. The primary factor plan is $5{\times}2{\times}3{\times}2$. The independent variable are neckline(5), trousers or skirt style(2), somatotype(3), culture(2), and the dependant variables are physical visual effect and the favor of clothe design. In cases of Korean, thin somatotype had better were V-neckline suit for looking shoulders wide because they have too narrow shoulders, and were pants suit than skirt suit for looking pelvis major. thin somatotype person who wants to look tall should wear china collar or tailored collar suit with pants. If she wears round neckline suit with skirt, the lower part of body and the height look tall. Pants suit with V neckline and skirt suit with china collar make standard somatotype looked having wide shoulders. Standard somatotype person with wide shoulder should avoid this style. The size of waist and pelvis was looked thick in round neckline and was looked thin in V neckline. So it will be better to find the right suit for one's weakness. Obesity had better wear V neckline to look neck slim and not wear stand and tailored collar. When obesity person wears pants suit, she is looked having slim waist than skirt suit. In case of American, thin somatotype in pants suit looks much taller than in skirt suit when she wears round neckline and stand collar suit. Standard somatotype has no difference because it is the basic shapes. Generally, it goes with all kinds of suit design. The belly and pelvis of American's obesity look fatter and bigger than Korean's obesity. The same with Korean, round neckline suit makes obesity looked belly and pelvis fat and big.

• 대한물리의학회지
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• 제6권2호
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• pp.153-163
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• 2011

Purpose: This study was conducted to compare the effect of visual feedback training using mirror and the training without mirror on the balance in people with hemiplegic paralysis. Methods: A total of 26 stroke patients were enrolled in this study. The participants were allocated randomly to 2 groups : visual feedback training group(n=13) and control group(n=13). Both groups received PNF(proprioceptive neuromuscular facilitation) for 5 times(each 30 minutes) per week over 6 weeks period. The group, which is enrolled in visual feed back training, performed additional exercise in front of mirror for 30 minutes. The control group performed same exercise without mirror. The data was analyzed using a paired t-test and independent t-test to determine the statistical significance. Results: The visual feedback training group showed significantly increased foot pressure and total pressure compared to the control group(p<.05) and significantly decreased body sway compared to the control group (p<.05). Also, visual feedback training group showed significant increase on the Berg Balance Scale(BBS), Timed Up and Go test(TUG) compared to the control group(p<.05). Conclusion: These results support the perceived benefits of visual feedback training using mirror to augment the balance of stroke patients. Therefore, visual feedback training using mirror is feasible and suitable for stroke patients.

• Journal of Preventive Medicine and Public Health
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• 제25권1호
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• pp.44-52
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• 1992

This study was conducted to evaluate the relations between alcohol intake and blood lipid level in a group of 1,138 Korean adult men, ages 20 to 69 years. Total number of each of a variety of drinks in the previous two weeks was obtained by questionnaire and converted into grams of alcohol consumed in a week. The levels of blood lipid such as Cholesterol, HDL-Cholesterol, Triglyceride and LDL-Cholesterol were examined by enzyme method. We also observed the effects of various variables such as age, body mass index, smoking, exercise and blood pressure on blood lipid level. The results obtained were as follows : 1. Average weekly alcohol intake was $129.0{\pm}167.4gm$ and that of 30-39 age group was the highest as $149.3{\pm}170.4gm$. 2. Levels of Cholesterol Triglyceride and LDL-Cholesterol tended to increase with increasing age, but level of HDL-Cholesterol showed no significant relationship with age. 3. The positive linear regressions of alcohol intake on HDL-Cholesterol and Triglyceride were noted statistically significant. 4. Multiple regression analysis demonstrated that the effect of alcohol on HDL-Cholesterol and Triglyceride was statistically significant and the contribution rates were 5.0% and 0.8%, respectively. And, in the case of HDL-Cholesterol, the alcohol intake was the most significant independent variable.

• The Journal of Korean Physical Therapy
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• 제16권3호
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• pp.161-175
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• 2004

The purpose of this study was to determine the effect of HPAFO(Hinged Plastic Ankle Foot orthosis) and SPAFO(Solid Plastic Ankle Foot Orthosis) on standing balance and step moving in hemiplegia patients. Twenty hemiplegic patients were either inpatient or outpatient at the Rehabilitation medicine, MokPo J General Hospital and JeonJu J Medical Center from July 15, 2002 to September 15, 2002. Patients were able to ambulate independently for at least 10 meters and to stand independently for at least 10 minutes with balance measurement tool. The static balance and dynamic activity measurement was determined by SAKAI active balancer(Japan) with wearing HPAFO and wearing SPAFO. The static balance and dynamic activity analysis was analyzed by independent t-test. The results were as follows: 1. There were no significant difference in body weight bearing percent between wearing HPAFO and wearing SPAFO(p>0.05). 2. There were significant difference in whole path length between wearing HPAFO and wearing SPAFO(p<0.05). 3. There were significant difference in Effective Value Area between wearing HPAFO and wearing SPAFO(p>0.001). 4. There were significant difference in repeated functional time between wearing HPAFO and wearing SPAFO(p>0.001). 5. There were significant difference in cadence between wearing HPAFO and wearing SPAFO(p>0.001). The result of this study showed that wearing HPAFO and wearing SPAFO gave fair amount of improvement to static standing balance and dynamic movement ability of hemiplegic patients. The comparison result showed significant differences in between HPAFO and SPAHFO. The result of this study had a general limitation due to the restricted number of cases. The future study needs more detailed research and comparison with various variance between these two orthoses.

• Toxicological Research
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• 제6권2호
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• pp.167-182
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• 1990

Dietary restriction (caloric restriction) is the only intervention which has been reliably shown to extend the maximum life span of warm-blooded animals and delay the many phenomena associated with aging. It is also one of the most effective modulators of toxicity, especially cancer endpoints. In spite of the known modulator effects of caloric restriction, the biological mechanisms responsible for these effects had not been in vestigated until recently. The National Center for Toxicological Research (NCTR), in a collaborative effort with the National Institute of Aging (NIA), initiated a project whereby nine (9) combinations of rodent species/strains and diets were fed both restricted and ad libitum. The NIA's initiative was to identify biomarkers of aging whereas NCTR's initiative was to identify the biological effects associated with the profound effects caloric restriction has in protecting against both spontaneous (age-related) and chemically-induced toxic endpoints. Independent of sex or species, caloric restriction has similar effects on body temperature, oxygen consumption and $CO_2$production. Caloric restriction also decreased lipid glycolysis and metabolism in rats and mice, which suggest decreased production of metabolites which could lead to fatty acid epoxide formation. The age-associated loss of ciradian regulation of intermediate enzymes is also significantly reduced. Moreover, caloric restriction reduced the age-associated feminization of sexually dimorphic liver isozymes, increased several glucocorticoid responsive isozymes, elevated glucagon/insulin ratios, produced less microsomal superoxide and enhanced the capacity for utilzing detoxicating metabolic pathways. Calorically restricted rats have less than half the number of aflatoxin ($AFB_1$)-DNA adducts than ad libitum animals and urinary excretion of $AFB_1$ was increased significantly. Finally, DNA repair mechanisms are enhanced and oncogene expression is decreased in calorically restricted animals.

• 한국임상수의학회지
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• 제37권2호
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• pp.82-87
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• 2020

The purpose of this study is to evaluate the azygos vein to aorta diameter ratio (AV/AO ratio) in healthy dogs and dogs with diseases that may cause azygos vein dilation. The normal groups included eleven healthy beagle dogs and eleven small breed dogs. The abnormal group included 43 dogs that had diseases with high right atrial pressure (RA group), obstruction of cranial or caudal vena cava (CVC group) and porto-azygos shunt group (PSS group). The diameter of AV and AO were measured at three sites on thoracic CT images; the level of the cranial endplate of 12^th thoracic vertebra (TV level), the tracheal bifurcation (TB level) and the insertion to the cranial vena cava (CrVC level). The AV/AO ratio at the CrVC level had significantly higher values than those at the TV and TB levels in the normal groups. The AV/AO ratios of TV and TB levels in the CVC group and the values at all measurement sites of the PSS group were significantly higher than the normal groups. AV/AO ratio will be a useful factor for the evaluation of various clinical conditions that change the AV diameter with respect independent to the body weight in dogs.

• 대한토목학회논문집
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• 제38권1호
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• pp.103-112
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• 2018

수도권지역의 교통행정운영의 문제점을 해결하기 위해서 현재 새로운 수도권 광역교통행정기구의 설립이 가시화되고 있다. 본 연구는 수도권 광역교통행정기구의 성공적인 설립과 운영을 위해서는 어떠한 행정구조와 업무기능을 가져야 하는지를 고찰해 보았다. 이를 위하여 전문가설문을 이용한 AHP기법을 적용하여 최선의 적용가능한 대안을 제시하였다. 본연구의 분석결과는 수도권교통기구설립 대안을 평가할 때, 실제교통 행정의 운영주체 또는 그 운영비용보다는 전체 교통서비스의 질적 향상, 개인교통복지 증진, 그리고 이를 추진할 수 있는 강력한 정치 행정력에 더 높은 의미와 중요성을 강조하고 있다. 이러한 관점에서 본연구는 수도권광역교통청을 중앙정부내 별청형태로 신설하여 수도권내 장기종합교통체계를 통합관리하도록 제안하였다.