• Archives of Pharmacal Research
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• 제13권2호
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• pp.151-160
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• 1990

In order to develop a controlled-release oral drug delivery system (DDS) which sustains the plasma acetaminophen (AAP) concentration for a certain period of time, microporous membrane-coated tablets were prepared and evaluated in vitro. Firstly, highly water-soluble core tablet of AAP were prepared with various formulations by wet granulation and compression technique. Then the core tablets were coated with polyvinychloride (PVC) in which micronized sucrose particles were dispersed. Effect of formula compositions of core tablets and coating suspensions on the pharmaceutical characteristics such as drug release kinetics and membrane stability of the coated tablets was investigated in vitro. AAP was released from the coated tablets as a zero-order rate in a pH-independent manner. This independency of AAP release to pH change from 1.2 to 7.2 is favorable for the controlled oral drug delivery, since it will produce a constant drug release in the stomach and intestine regardless of the pH change in the GI tract. Drug release could be extended upto 10 h according to the coating condition. The release rate could be controlled by changing the formula compositions of the core tablets and coating suspensions, coat weight per each tablet, and especially PVC/sucrose ratio and particle size of the sucrose in the coating suspension. The coated tablets prepared in this study had a fairly good pharmaceutical characteristics in vitro, however, overall evaluation of the coated tablet should await in vivo absorption study in man.

• 전기학회논문지
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• 제57권6호
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• pp.924-931
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• 2008

This paper presents a buswise transmission loss allocation algorithm utilizing the transaction strategy. We prove that whatever calculated by any transaction strategy, the total of the allocated transmission losses of each bus, including no-load loss allocation, almost equals the total loss of AC power flow algorithm and the loss is perfectly slackbus-independent. In this paper, the allocated transmission losses of each bus is calculated by the method of integrating loss sensitivities using by the load level parameter ${\lambda}$. The performance of the proposed algorithm is evaluated by the case studies carried out on the WSCC 9-bus and IEEE 14-bus systems.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회B
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• pp.2558-2562
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• 2007

In the present work, flow characteristics analysis has been performed for steam turbine bypass control valve (single-path type). The numerical analysis is performed by solving three-dimensional Reynolds-averaged Navier-Stokes (RANS) equations. Shear stress transport (SST) model is used as turbulence closure. Symmetry condition is applied at the mid plane of the valve while adiabatic condition is used at the outer wall of the cage. Grid independency test is performed to find the optimal number of grid points. The pressure and temperature distributions on the outer wall of the cage are analyzed. Mass flow rate at maximum plug opening condition is compared with the designed mass flow rate.

• 교육시설
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• 제13권2호
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• pp.34-41
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• 2006

A multi-sected campus can be explained as an university to be consisted of several campuses, which are physically separate, but are functionally interconnected. The basic structure of university campuses started with a single-nuclei structure of which the facilities were layed out around a single campus core, and it has been changed to multi-nuclei layout, where a single campus core was subdivided into several service cores due to increased service demands. The limitation on the expansion of campuses due to urbanization of surroundings leads to the physical separation of the campuses, and the development of information technology made it possible to connect physically-separate campuses to form the multi-sected campus. The three general characteristics of multi-sected campuses were found; 1) the need for programatic specialization of each individual campus, 2) the need for representative imageability for each campus, 3) necessity for physical connectivity between campuses and functional independency for each campus.

• 대한음성학회지:말소리
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• 제52호
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• pp.111-120
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• 2004

This paper focuses on the DSP implementation of an HMM-based speech recognizer that can handle several hundred words of vocabulary size as well as speaker independency. First, we develop an HMM-based speech recognition system on the PC that operates on the frame basis with parallel processing of feature extraction and Viterbi decoding to make the processing delay as small as possible. Many techniques such as linear discriminant analysis, state-based Gaussian selection, and phonetic tied mixture model are employed for reduction of computational burden and memory size. The system is then properly optimized and compiled on the TMS320C6711 DSP for real-time operation. The implemented system uses 486kbytes of memory for data and acoustic models, and 24.5 kbytes for program code. Maximum required time of 29.2 ms for processing a frame of 32 ms of speech validates real-time operation of the implemented system.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2005년도 가을 학술발표논문집 Vol.32 No.2 (1)
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• pp.925-927
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• 2005

급속도로 IT 산업이 발전하면서, 리소스가 제한된 소형 기기들의 사용이 비약적으로 증가하는 추세이다. 자바는 플랫폼 독립성(Platform Independency), 보안성(Security), 이동성(Mobility) 등의 장점을 가지고 있기 때문에 성능을 극대화하고 안정된 서비스를 제공해야 하는 소형기기들에게 핵심 소프트웨어 플랫폼으로 많이 사용되고 있다. 임베디드 장치나 모바일 시스템과 같은 제한된 리소스를 사용하는 기기들은 자바 어플리케이션 수행을 위해 자바의 소프트웨어 플랫폼중의 하나인 K 가상 머신(K Virtual Machine: KVM)을 탑재하여 사용한다. 본 논문에서는 KVM 가비지 컬랙션의 지연 시간(Pause-Time)과 Tracing 의 수행 빈도수를 줄여 임베디드 환경에서 성능 향상을 위한 가비지 컬랙션을 설계하고 구현한 내용을 기술한다.

• 산업공학
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• 제25권1호
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• pp.79-86
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• 2012

Traditional business process management systems provide verification tools of process models to deploy and automate the models. However, there are not so many studies on how to maintain systematically collaborative process models such as supply chain processes when companies are willing to change and update the collaborative process models. In this paper, we analyze change patterns of collaborative processes and declare 19 change patterns. In addition, we apply the change patterns to the process interoperability patterns in order to identify the change problems in case of independent process changes of collaborative processes. As a result, we devise an independency checking algorithm of process changes in collaborative processes.

• Journal of international Conference on Electrical Machines and Systems
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• 제2권4호
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• pp.429-435
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• 2013

This paper proposes a sensorless speed control based on a novel extension of the torque producing flux (active flux) observer for the surface mounted permanent magnet synchronous machines (SPMSM) without additional high frequency signal injection. From the estimated torque producing flux, the rotor position and speed can be calculated at low speed due to their independency. Therefore, no rotor position sensor is required. Two approaches of the torque producing flux observer are presented and compared. The results show the stability and robustness of the expansion of the torque producing flux observer at low speed for the SPMSM.

• 로봇학회논문지
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• 제12권3호
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• pp.258-262
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• 2017

In this paper, we propose a new collision detection algorithm for human-robot collaboration. We use an IMU sensor located at the tip of the manipulator and the kinematic behavior of the manipulator to detect the unexpected collision between the robotic manipulator and environment. Unlike other method, the developed algorithm uses only the kinematic relationship between the manipulator joint and the end effector. Therefore, the collision estimation signal is not affected by the error of the dynamics model. The proposed collision detection algorithm detects the collision by comparing the estimated acceleration of the end effector derived from the position, velocity and acceleration trajectories of the robot joints with the actual acceleration measured by the sensor. In simulation, we compare the performance of our method with the conventional Residual Observer (ROB). Our method is less sensitive to the load variation because of the independency on the dynamic modeling of the manipulator.

• 대한기계학회논문집B
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• 제24권1호
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• pp.85-92
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• 2000

Easy measurement method of orthogonal triple-sensor hot-wire anemometer is developed. Advantages of the new method is that it does not require either the exact orthogonality of the installed wires which cannot be kept during the probe manufacture and repair, nor the knowledge of the wire installation angles and the yaw and pitch coefficient of the wires. The new method introduced yaw and pitch calibration coefficients which are designed to increase monotonically with yaw and pitch angles. So the resulting calibration network is simple to recognize compared with that of the previously suggested calibration method. Verification experiments showed good accuracy and independency of the directional calibration on velocity.