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Natural Convection Heat Transfer in Rectangular Air Enclosures With Adiabatic and Isothermal Horizontal Boundary Conditions (단열 및 등온수평 경계조건을 갖는 직각 밀폐용기내 공기의 자연대류 열전달)

  • 이진호;김무현;모정하
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.14 no.1
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    • pp.207-213
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    • 1990
  • Natural convection heat transfer in rectangular air enclosure was studied interferometrically and numerically for the use of adiabatic and constant temperature horizontal boundary conditions. In the isothermal horizontal boundary case with the temperature difference ratio, .DELTA. $T_{v/}$.DELTA. $T_{H}$ .simeq. 1 temperature distribution in the enclosure is strongly stratified and the average Nusselt Number is higher than that of adiabatic horizontal boundary case.ase.

Effects of Caprylic Acid and Cyclodextrin Complex on In vitro Fermentation Characteristics and Methane Production (Caprylic Acid와 Cyclodextrin 복합물이 In vitro 반추위 발효성상 및 메탄 생성에 미치는 영향)

  • Kim, K.H.;Seol, Y.J.;Lee, S.S.;Oh, Y.G.;Nam, I.S.;Kim, D.H.;Choi, C.W.
    • Journal of Animal Science and Technology
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    • v.49 no.5
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    • pp.657-666
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    • 2007
  • This study was conducted to evaluate the effects of dietary addition of caprylic acid(CA)-cyclodextrin (CD) complex on in vitro fermentation characteristics, total gas and methane production. Experiment was done with six treatment groups; 1) no CA-CD complex(control), 2) CA 20 mg(T1), 3) CD 830 mg(T2), 4) CA-CD complex 425 mg(T3), CA-CD complex 850mg(T4), CA-CD complex 1,700 mg(T5). Ruminal pH, ammonia and total VFA concentrations of T2, T3, T4 and T5 were lower(P<0.05) than those of control and T1 for the 12h incubation. The increase in molar percentage of propionate was observed in T4 and T5 compared with control and T2 for the 8h incubation(P<0.05), however, the ratio of acetate to propionate was unchanged in all treatments. Total gas of T1 was lower than that of control, but T2, T3, T4 and T5 were higher compared with control for 12h incubation(P<0.05). If the methane ratio (as %) to total gas for all treatments was compared, T3, T4 and T5(CA-CD supplemented groups) averaged 2.7% whereas control, T1 and T2 showed 3.4, 2.8 and 5.1%, respectively. Therefore, according to these results, it might be concluded that supplementation of CA-CD complex could reduce methane production without disrupting ruminal fermentation.

Heterogeneity of Human γδ T Cells and Their Role in Cancer Immunity

  • Hye Won Lee;Yun Shin Chung;Tae Jin Kim
    • IMMUNE NETWORK
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    • v.20 no.1
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    • pp.5.1-5.15
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    • 2020
  • The γδ T cells are unconventional lymphocytes that function in both innate and adaptive immune responses against various intracellular and infectious stresses. The γδ T cells can be exploited as cancer-killing effector cells since γδ TCRs recognize MHC-like molecules and growth factor receptors that are upregulated in cancer cells, and γδ T cells can differentiate into cytotoxic effector cells. However, γδ T cells may also promote tumor progression by secreting IL-17 or other cytokines. Therefore, it is essential to understand how the differentiation and homeostasis of γδ T cells are regulated and whether distinct γδ T cell subsets have different functions. Human γδ T cells are classified into Vδ2 and non-Vδ2 γδ T cells. The majority of Vδ2 γδ T cells are Vγ9δ2 T cells that recognize pyrophosphorylated isoprenoids generated by the dysregulated mevalonate pathway. In contrast, Vδ1 T cells expand from initially diverse TCR repertoire in patients with infectious diseases and cancers. The ligands of Vδ1 T cells are diverse and include the growth factor receptors such as endothelial protein C receptor. Both Vδ1 and Vδ2 γδ T cells are implicated to have immunotherapeutic potentials for cancers, but the detailed elucidation of the distinct characteristics of 2 populations will be required to enhance the immunotherapeutic potential of γδ T cells. Here, we summarize recent progress regarding cancer immunology of human γδ T cells, including their development, heterogeneity, and plasticity, the putative mechanisms underlying ligand recognition and activation, and their dual effects on tumor progression in the tumor microenvironment.

T Cell Immune Responses against SARS-CoV-2 in the With Corona Era

  • Ji-Eun Oh
    • Biomedical Science Letters
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    • v.28 no.4
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    • pp.211-222
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    • 2022
  • After more than two years of efforts to end the corona pandemic, a gradual recovery is starting in countries with high vaccination rates. Easing public health policies for a full-fledged post-corona era, such as lifting the mandatory use of outdoor mask and quarantine measures in entry have been considered in Korea. However, the continuous emergence of new variants of SARS-CoV-2 and limitations in vaccine efficacy still remain challenging. Fortunately, T cells and memory T cells, which are key components of adaptive immunity appear to contribute substantially in COVID-19 control. SARS-CoV-2 specific CD4+/CD8+ T cells are induced by natural infection or vaccination, and rapid induction and activation of T cells is mainly associated with viral clearance and attenuated clinical severity. In addition, T cell responses induced by recognition of a wide range of epitopes were minimally affected and conserved against the highly infectious subsets of omicron variants. Polyfunctional SARS-CoV-2 specific T cell memory including stem cell-like memory T cells were also developed in COVID-19 convalescent patients, suggesting long lasting protective T cell immunity. Thus, a robust T-cell immune response appears to serve as a reliable and long-term component of host protection in the context of reduced efficacy of humoral immunity and persistent mutations and/or immune escape.

Effect of Biofertilizers on Vegetative Growth of Okra

  • Ashrafuzzaman, M.;Nuruzzaman, M.;Islam, M.Zahurul;Islam, M.Rafiqul
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.48 no.2
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    • pp.73-80
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    • 2003
  • An experiment was carried out at the Field Laboratory of the Department of Crop Botany, Bangladesh Agricultural University, Mymensingh from March to July, 2001 to investigate the effect of biofertilizers on morpho-physiological characters of okra. The experiment was laid out in a randomized complete block design with four replications. There were nine treatments such as $\textrm{T}_0$ (control), $\textrm{T}_1$ (Azotobacter biofertilizer), $\textrm{T}_2$ (Azospirillum biofertilizer), $\textrm{T}_3$ (Azotobacter+Azospirillum biofertilizers), $\textrm{T}_4$ (Azotobacter+Cowdung 5 ton $\textrm{ha}^{-1}$), $\textrm{T}_5$ (Azospirillum+Cowdung 5 ton $\textrm{ha}^{-1}$), $\textrm{T}_6$(Azotobacter+Azospirillum+Cowdung 5 ton $\textrm{ha}^{-1}$), $\textrm{T}_7$ (Cowdung 5 ton $\textrm{ha}^{-1}$) and $\textrm{T}_8$ (60% Nitrogen). The experimental results revealed that significant variations exist among the treatments regarding morphological characters e.g. plant height, number of leaves/plant, stem base diameter, tap root length, and physiological characters like, root dry weight, leaf area index and crop growth rate. Number of leaves/plant, stem base diameter, root length, root dry weight, leaf area index and crop growth rate were found higher in $\textrm{T}_4$, $\textrm{T}_5$, $\textrm{T}_6$ and $\textrm{T}_8$ than the others. In all the parameters, $\textrm{T}_8$ gave the similar result with biofertilizers in combination with cowdung treatments and $\textrm{T}_7$ showed identical with $\textrm{T}_0$ (control). Biofertilizer treatments had insignificant effect on 1000-seed weight(g). Experimental results mentioned above revealed that morpho-physioligical characters of okra could be modified by the application of biofertilizer+cowdung. However, biofertilizers+Cowdung treatments were comparable to $\textrm{T}_8$(60% Nitrogen) in this study. This suggests that $\textrm{T}_4$ or $\textrm{T}_6$ or $\textrm{T}_5$ were more benificial in environmentally friendly okra cultivation and may be used as an alternative of inorganic nitrogen by saving cost of production and sustaining productivity.

Development of an IoT Smart Home System Using BLE (BLE통신을 이용한 IoT 스마트홈 모니터링 시스템 개발)

  • Duong, Cong Tan;Kim, Myung Kyun
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.6
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    • pp.909-917
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    • 2018
  • Recently, the Internet of Thing (IoT) technology is expanding explosively in the number of devices and applications in many application areas. In IoT systems, sensors and actuators are connected to the Internet and cooperate to do some applications by exchanging information. In this paper an IoT smart home system is developed to monitor and control home devices easily. Our system consists of sensor devices, IoT gateways, and an IoT server. Sensor devices developed using Rfduino sense the physical world and transmit their data using BLE to the IoT server thru the IoT gateway. We implemented the IoT gateway using Raspberry Pi and the IoT server using ARTIK cloud. We installed our system and made a test in our lab, which showed that our system can be installed and managed easily and extended its functionality in an easy way. By taking advantage of the rule mechanism and action messages of ARTIK cloud, we implemented the control of device parameters easily by sending action messages to the ARTIK cloud.

Effects of Supplementary Chinese Milk Vetch Silage and Rapeseed Meal on the Performance and Rumen Fermentation of Lambs Given Ammoniated Rice Straw Based Diet

  • Wu, Yueming;Liu, Jian Xin;Chen, Zhenming
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.4
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    • pp.455-461
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    • 1998
  • This study was proposed to investigate effects of inclusion of Chinese milk vetch silage (MVS) and rapeseed meal (RSM) on the growth and rumen fermentation of Hu-sheep. Fifty weanling lambs were randomly divided into five equal groups and offered ammoniated rice straw (ABRS) ad libitum along with 100 g concentrate (Trial 1). The animals in $T_0$, $T_1$, $T_2$, $T_3$ and $T_4$ group were respectively supplemented with MVS at levels of 0, 0, 7, 14 or 21% and with RSM at levels of 0, 15, 10, 5 or 0%. Daily gain of lambs was significantly (p<0.05) higher in $T_1$, $T_2$ and $T_3$ group than that in $T_0$ and $T_4$ group. Feed conversion ratio was greatly reduced in supplemented groups as compared with $T_0$ group. In trial 2, five sheep with rumen cannulae were used in a $5{\times}5$ Latin square design. The experimental treatments were as described in Trial 1, but without concentrate. The intake of AVRS was significantly (p<0.05) lower in $T_4$ group than that in $T_0$ group, and also significantly (p<0.05) lower than those in $T_1$ and $T_2$ group. Little difference among all treatments was found in 48h DM degradability of ABRS, MVS and RSM, and in rumen pH value and microbial protein concentration. Rumen concentrations of individual and total VFA tended to be higher in supplemented groups than those in $T_0$ group.These rusults suggest that supplementation with RSM or RSM plus MVS can effectively improve the performance of lambs, and may fail to influence markedly the rumen digestion of ABRS and rumen environments.

Institutional Improvements for Security of IoT Devices (IoT 기기의 보안성 확보를 위한 제도적 개선방안)

  • Lee, Donghyeok;Park, Namje
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.27 no.3
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    • pp.607-615
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    • 2017
  • Recently, IoT products with various functions are being developed. Through the combination of objects and information technology, convenient services that have not been imagined before are emerging. For a secure IoT environment, product security must be considered. However, the existing IoT products have various problems such as security vulnerability. In order to secure the security of IoT products, technical countermeasures as well as policy responses are needed. However, the legislation related to current IoT products has a limit to guarantee safety in IoT environment. In this paper, we analyze the limitations of the current legal system of IoT, and suggests ways to improve it.

Implementation of crypto key-based IoT network security system (암호키 기반 IoT 네트워크 보안 시스템 구현)

  • Jeon, Ji-Soo;Kang, Dong-Yeon;Han, Sung-Hwa
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.10a
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    • pp.349-350
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    • 2022
  • As research on IT convergence continues, the scope of IoT (Internet of Things) services continues to expand. The IoT service uses a device suitable for the purpose. These IoT devices require an authentication function. In addition, in IoT services that handle important information such as personal information, security of transmission data is required. In this study, we implement a crypto key-based IoT network security system that can authenticate devices for IoT services and securely transmit data between devices. Through this study, IoT service can authenticate the device itself and maintain the confidentiality of transmitted data. However, since it is an IoT service, additional research on the application efficiency of the encryption algorithm is required.

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A Study on Changes of Serum $fT_3\;and\;rT_3$ Concentration in Nonthyroidal Critical Illness (비갑상선 중증 질환에서 혈청 $fT_3$$rT_3$의 변화에 관한 연구)

  • Lee, Jong-Wha;Kim, Ju-Ock;Yu, Cheol-Jae;Moon, Youn-Sung;Shin, Young-Tae;Ro, Heung-Kyu
    • The Korean Journal of Nuclear Medicine
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    • v.19 no.1
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    • pp.103-111
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    • 1985
  • Recently changes in thyroid physiology during acute and chronic medical illness were demonstrated. The serum $fT_3,\;rT_3,\;T_4,\;T_3,\;fT_4$, and TSH concentration were measured by radioimmunoassay method in 49 patients with critical illness and 10 normal subjects to assess the change of thyroid function in critical illness. The results were as follows; 1) The mean serum $fT_3$ concentration was $6.68{\pm}1.05pmol/ml$ in normal subjects while in patients with critical illness the serum $fT_3$ concentration was significantly lowered to $1.55{\pm}1.15pmol/ml$(p<0.001). 2) The mean serum $rT_3$ concentration was $0.22{\pm}0.44ng/ml$ in normal subjects and $0.42{\pm}0.37ng/ml$ in patient with critical illness. There was increment in critically ill patients as compared to normal subjects but no statistically significant difference(p>0.05). 3) The mean serum $T_3$ concentration was $1.24{\pm}0.25ng/ml$ in normal subjects and $0.56{\pm}0.56ng/ml$ in patients with criticial illness and there was significant difference in each other(p<0.005). 4) The mean serum $T_4,\;fT_4$, and TSH concentrations were $7.80{\pm}1.02{\mu}g/dl,\;1.26{\pm}0.39ng/dl,\;1.87{\pm}0.45{\mu}U/ml$ in normal subjects respectively and $6.02{\pm}3.06{\mu}g/dl,\;1.46{\pm}0.80ng/dl,\;1.74{\pm}0.79{\mu}U/ml$ in patients with critical illness and there was no significant difference between critically ill patients and normal subjects. 5) The ratio of mean serum concentration of $fT_3$ and $rT_3(fT_3/rT_3)$, $30.42{\pm}5.58$ in normal subjects was significantly higher(p<0.005) than the coresponding patients with critical illness. 6) The mean serum $fT_3$ concentration in expired cases(n=12) during admission was significant difference between expired and survived cases(p<0.005). The mean serum $rT_3$ centration was $0.67{\pm}0.58ng/ml$ in expired cases and $0.34{\pm}0.22ng/ml$ in survived cases with significant difference(p<0.005). Half of the cases who showed less than $3{\mu}g/dl$ of serum $T_4$ level were expired.

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