• Journal of the Optical Society of Korea
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• v.14 no.1
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• pp.42-48
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• 2010

We used video-rate Confocal Laser Scanning Microscopy (CLSM) to observe the motion of blood cells in a micro-channel. Video-rate CLSM allowed us to acquire images at the rate of 30 frames per second. The acquired images were used to perform Particle Image Velocimetry (PIV), thus providing the velocity profile of the blood in a micro-channel. While previous confocal microscopy-assisted PIV required exogenous micro/nano particles as the tracing particles, we employed blood cells as tracing particles for the CLSM in the reflection mode, which uses light back-scattered from the sample. The blood flow at various depths of the micro-channel was observed by adjusting the image plane of the microscope. The velocity profile at different depths of the channel was measured. The confocal micro-PIV technique used in the study was able to measure blood velocity up to a few hundreds ${\mu}m/sec$, equivalent to the blood velocity in the capillaries of a live animal. It is expected that the technique presented can be applied for in vivo blood flow measurement in the capillaries of live animals.

• Journal of Cardiovascular Imaging
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• v.30 no.4
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• pp.279-289
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• 2022

BACKGROUND: In many cardiovascular disorders, the contractile performance of the right ventricle (RV) is the primary determinant of prognosis. For evaluating RV volumes and function, 4 dimensional (4D)-echocardiography has become common. This research used 2D and 4D modalities to assess RV contractile performance in hypertensive patients. METHODS: A total of 150 patients with essential hypertension were enrolled in this study, along with 75 age and sex-matched volunteers. Clinical evaluation and echocardiographic examination (including M-mode, tissue Doppler imaging, and 2D speckle tracking) were conducted on all participants. RV volumes, 4D-ejection fraction (EF), 4D-fractional area change (FAC), 4D-tricuspid annular plane systolic excursion (TAPSE), 4D-septal and free wall (FW) strain were all measured using 4D-echocardiography. RESULTS: Hypertensive patients showed 2D-RV systolic and diastolic dysfunction (including TAPSE, 2D-right ventricular global longitudinal strain, RV-myocardial performance index and average E/EaRV) and 4D-RV impairment (including right ventricular EF, FAC, RV strain and TAPSE, right ventricular end-diastolic volume and right ventricular end-systolic volume) compared to the control group. We verified the prevalence of RV systolic dysfunction in hypertension patients using the following parameters: 1) 15% of them had 2D-TAPSE < 17 mm vs. 40% by 4D-TAPSE; 2) 25% of them had 2D-GLS < 19% vs. 42% by 4D-septal strain and 35% by 4D FW strain; 3) 35% of hypertensive patients had 4D-EF < 45%; and finally; 4) 25% of hypertensive patients had 2D-FAC < 35% compared to 45% by 4D-FAC. CONCLUSIONS: The incidence of RV involvement was greater in 4D than in 2D-modality trans-thoracic echocardiography. We speculated that 4D-echocardiography with 4D-strain imaging would be more beneficial for examining RV morphology and function in hypertensive patients than 2D-echocardiography, since 4D-echocardiography could estimate RV volumes and function without making geometric assumptions.

• Steel and Composite Structures
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• v.19 no.5
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• pp.1095-1113
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• 2015

In order to determine the mechanical behavior of the curved laminates in practical applications, three right-angled composite brackets with different lay-ups were investigated both experimentally and numerically. In the experimental, quasi-static tests on both unidirectional and multidirectional curved composite brackets were conducted to study the progressive failure and failure modes of the curved laminates. In the numerical modeling, three-dimensional finite element analysis was used to simulate the mechanical behavior of the laminates. Here, a strength-based failure criterion, namely the Ye criterion, was used to predict the delamination failure in the composite curved laminates. The mechanical responses of the laminate subjected to off-axis tensile loading were analyzed, which include the progressive failure, the failure locations, the load-displacement relationships, the load-strain relationships, and the stress distribution around the curved region of the angled bracket. Subsequently, the effects of stacking sequence and thickness on the load carrying capacity and the stiffness of the laminates were discussed in detail. Through the experimental observation and analysis, it was found that the failure mode of all the specimens is delamination, which is initiated abruptly and develops unstably on the symmetric plane, close to the inner surface, and about $29^{\circ}$ along the circumferential direction. It was also found that the stacking sequence and the thickness have significant influences on both the load carrying capacity and the stiffness of the laminates. However, the thickness effect is less than that on the curved aluminum plate.

• The Korean Journal of Zoology
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• v.33 no.3
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• pp.322-329
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• 1990

The effects of retinoic acid (RA) on the regenerating limbs of Korean newt (Hynobius leechii) larvae have been studied. Intraperitoneal injection of RA at 4 days post-amputation caused the proximalization of regenerate structures in the proximodistal (PD) axis of the limbs amputated through either the distal zeugopodium or the distal stylopodium. The mean level of proximalization (MLP) increased as a dose-dependent manner, and the MLP was also dependent on the level of amputation at a given dose of RA. At the dose of 150 $\mu$ g/g body wt., MLP's in either amputation level reached close to a peak value, and an increasing number of inhibition of regeneration or duplication in the transverse plane occurred at the dose of 200 $\mu$ g/ g body wt. and above. The changes induced by RA treatment suggest that positional values in the cells of the regenerating limbs have been modified in the three cardinal axes including PD and transverse axes in a graded mode. Furthermore, from the comparison of data in two different amputation levels, it can be speculated that the sensitivity of cells to RA effect along the PD axis might not be linear.

• Journal of the Korean Geotechnical Society
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• v.28 no.7
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• pp.5-16
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• 2012

Soil-nailing is the most popular method of reinforcing for slope stability. In general, two factors are considered as failure modes during the soil-nailing design stages: pullout failure mode and shear failure mode that will occur on the most probable failure plane. In many cases, however, shallow failure can also occur when the ground near the slope face is swept away by the horizontal stress release during the staged top-down excavation. In this paper, an optimized soil-nailing design methodology is proposed by considering the three failure modes mentioned above: pullout failure; shear failure; and shallow failure. The variables to be optimized include the bonded length and number of soil-nailings, and the confining pressure that should be applied at the slope face. The procedure to obtain the optimized design variables is as follows: at first, optimization of soil-nailings, i.e. bonded length and number, against pullout and shear failure modes; and then, optimization of confining pressure at each excavation stage that is needed to prevent shallow failure. Since the two processes are linked with each other, they are repeated until the optimized design variables can be obtained satisfying all the constrained design requirements in both of the two processes.

• The Journal of the Acoustical Society of Korea
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• v.30 no.7
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• pp.361-367
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• 2011

Propagating waves (flexural, longitudinal and shear waves) travelling with constant amplitudes and evanescent waves decaying exponentially are generated on a cylindrical shell. Evanescent waves are generally generated in the vicinity of an vibration excitation point and near ends of the shell. But the evanescent waves can generates strong axial vibration at the ends of the cylindrical shell. The strong end axial vibration due to those evanescent waves has been observed in an author's previous paper dealing with measurements of the in-plane axial vibration of a finite cylindrical shell. In this paper the strong end axial vibration due to the evanescent waves has been theoretically analyzed. In order to analyze the vibration of the cylindrical shell, wave propagation approach has been implemented. Comparison between theoretical and experimental results for the axial vibration of the shell showed that the strong evanescent wave can be generated due to mode conversion (conversion from flexural wave to evanescent wave) at the ends of cylindrical shell. It also showed that the evanescent wave can generate the strong axial vibration near the ends of the cylindrical shell and that it can have effect even on 1/3 of the total length of the shell.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.11 no.5
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• pp.89-100
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• 2001

The Ritz method Is applied In a three-dimensional (3-D) analysis to obtain accurate frequencies for thick. linearly tapered. annular plates. The method is formulated for annular plates haying any combination of free or fixed boundaries at both Inner and outer edges. Admissible functions for the three displacement components are chosen as trigonometric functions in the circumferential co-ordinate. and a1gebraic polynomials in the radial and thickness co-ordinates. Upper bound convergence of the non-dimensional frequencies to the exact values within at least four significant figures is demonstrated. Comparisons of results for annular plates with linearly varying thickness are made with ones obtained by others using 2-D classical thin place theory. Extensive and accurate ( four significant figures ) frequencies are presented 7or completely free. thick, linearly tapered annular plates haying ratios of average place thickness to difference between outer radius (a) and inner radius (b) radios (h$_{m}$/L) of 0.1 and 0.2 for b/L=0.2 and 0.5. All 3-D modes are included in the analyses : e.g., flexural, thickness-shear. In-plane stretching, and torsional. Because frequency data liven is exact 7o a\ulcorner least four digits. It is benchmark data against which the results from other methods (e.g.. 2-D 7hick plate theory, finite element methods. finite difference methods) and may be compared. Throughout this work, Poisson\`s ratio $\upsilon$ is fixed at 0.3 for numerical calculations.s.

• Smart Structures and Systems
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• v.4 no.2
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• pp.209-220
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• 2008

A methodology for the seismic vulnerability assessment of historical monuments is presented in this paper. The ongoing work has been conducted in Tunisia within the framework of the FP6 European Union project (WIND-CHIME) on the use of appropriate modern seismic protective systems in the conservation of Mediterranean historical buildings in earthquake-prone areas. The case study is the five-century-old Zaouia of Sidi Kassem Djilizi, located downtown Tunis, the capital of Tunisia. Ambient vibration tests were conducted on the case study using a number of force-balance accelerometers placed at selected locations. The Enhanced Frequency Domain Decomposition (EFDD) technique was applied to extract the dynamic characteristics of the monument. A 3-D finite element model was developed and updated to obtain reasonable correlation between experimental and numerical modal properties. The set of parameters selected for the updating consists of the modulus of elasticity in each wall element of the finite element model. Seismic vulnerability assessment of the case study was carried out via three-dimensional time-history dynamic analyses of the structure. Dynamic stresses were computed and damage was evaluated according to a masonry specific plane failure criterion. Statistics on the occurrence, location and type of failure provide a general view for the probable damage level and mode. Results indicate a high vulnerability that confirms the need for intervention and retrofit.

• Plant Journal
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• v.4 no.3
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• pp.66-72
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• 2008

The vibration of steam turbine is caused by Mass unbalance, Shaft misalignment, Oil whip and rubbing etc. But in turbine which is normally operated and maintained, the Mass unbalance component possesses the greatest portion. Our power plant has two steam turbines in capacity of 200 MW and 135 MW respectively and each turbine is supported by 6 journal bearings. However, we had many difficulties because the vibration amplitude of #3 and #4 Bearings was high during the start-up and operation mode change of steam turbine. But, with this study, we completely solved the vibration problem caused by the mass unbalance of #1 steam turbine. Until a recent date, #3 and #4 bearings which support high pressure turbine for #1 steam turbine had shown about $135{\mu}m$ in vibration amplitude (sometimes it increased to $221{\mu}m$ maximum. alarm: 6 mils, trip: 9 mils) at base load. After applying the study, they decreased to about $45{\mu}m$ maximum. It is a result from that we did not change the setting value of bearing alignment and only changed the assembly position of internal parts in Synchro clutch coupling rachet wheel which links between high pressure turbine and low pressure turbine, and increased the internal gap and machining of the Pawl cage surface. In the operation of steam turbine, if the vibration value increases by 1X, we should reduce the vibration of bearing by weight balancing. However, unless the vibration of bearing is declined by the balancing, we will have to disassemble and check the component and find the cause. In this study, we researched the way to lower mass unbalance that is 1X vibration component which has the greatest portion of vibration generated by steam turbine and we got good result by applying the findings of this study.

• Journal of Korean Society of Steel Construction
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• v.14 no.5 s.60
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• pp.657-664
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• 2002

This paper described the ultimate strength and deformation limit of the new uniplanar T-joints in cold-formed square hollow sections. In the configuration of the new T-joint, only a branch member is orientated to a chord member at 45 degrees in the plane of the truss. This study focused on the branch-rotated T-joints that were governed by chord flange failure in previous studies. Test results of the T-joint in cold-formed square hollow sections revealed a deformation limit of 3%B for $16.7{\leq}2{\gamma}(=B/T){\leq}33.3$ and $0.27{\leq}{\beta}(=b1/B){\leq}0.6$. The existing strength formulae for traditional T-joint were determined and a new yield-line model for the branch-rotated T-joint proposed. Finally, the strength formula on the yield-line analysis was compared with test results and the application range of the proposed formula recommended.