• 국제물리치료학회지
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• 제10권2호
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• pp.1768-1773
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• 2019

Background: Aging reduces cognitive abilities, including visual memory (VM) and visual discrimination (VD). Since common cortical networks subserve eye movement and attention, voluntary eye movement may improve visual attention. Visual selective attention was major role for memory, and visual memory and visual attention are intimately related. Objective: To identify the improvement in VD and VM, after implementing the eye movement program consisting of saccadic eye movement (SEM) and pursuit eye movement (PEM) in the institutionalized healthy elderly. Design: Randomized controlled trial. Methods: The study involved a sample of 36 participants, and the mean age was 79.03 years (range 76~84 years). They were randomly allocated to the experimental group (n=16) and control group (n=20). Participants in the experimental group performed SEM 5 times per week for 4 weeks: twice daily at the same time in the morning and afternoon. The program was carried out for 3 minutes, and it consisted of SEM and PEM. The target's moving frequency was set at 0.5 Hz. VM and VD at the baseline and post-intervention were measured using Motor-Free Visual Perception test-4 (MFVPT-4). Results: VM significantly improved in the experimental group (p < .01), and significant differences were observed compared to the control group (p < .01). There was no significant change in VD. Conclusion: The eye movement program consisting of SEM and PEM increased VM more than VD. Therefore, eye movement program was feasible interventions for improving VM in institutionalized elderly persons.

• Journal of Ginseng Research
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• 제48권1호
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• pp.59-67
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• 2024

Background: Alzheimer's disease (AD) has memory impairment associated with aggregation of amyloid plaques and neurofibrillary tangles in the brain. Although anti-amyloid β (Aβ) protein antibody and chemical drugs can be prescribed in the clinic, they show adverse effects or low effectiveness. Therefore, the development of a new drug is necessarily needed. We focused on the cognitive function of Panax ginseng and tried to find active ingredient(s). We isolated panaxcerol D, a kind of glycosyl glyceride, from the non-saponin fraction of P. ginseng extract. Methods: We explored effects of acute or sub-chronic administration of panaxcerol D on cognitive function in scopolamine- or Aβ_25-35 peptide-treated mice measured by several behavioral tests. After behavioral tests, we tried to unveil the underlying mechanism of panaxcerol D on its cognitive function by Western blotting. Results: We found that pananxcerol D reversed short-term, long-term and object recognition memory impairments. The decreased extracellular signal-regulated kinases (ERK) or Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) in scopolamine-treated mice was normalized by acute administration of panaxcerol D. Glial fibrillary acidic protein (GFAP), caspase 3, NF-kB p65, synaptophysin and brainderived neurotrophic factor (BDNF) expression levels in Aβ_25-35 peptide-treated mice were modulated by sub-chronic administration of panaxcerol D. Conclusion: Pananxcerol D could improve memory impairments caused by cholinergic blockade or Aβ accumulation through increased phosphorylation level of ERK or its anti-inflammatory effect. Thus, panaxcerol D as one of non-saponin compounds could be used as an active ingredient of P. ginseng for improving cognitive function.

• 정보과학회 논문지
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• 제43권2호
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• pp.177-185
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• 2016

본 논문에서는 NVRAM과 DRAM으로 구성된 SSD의 쓰기 버퍼 구조 및 제안된 쓰기 버퍼 구조에 적합한 이중 쓰기 버퍼 알고리즘을 제안한다. 읽기/쓰기 작업이 혼합된 일반적인 워크로드에서 저장 장치의 성능을 향상시키기 위해서 읽기 작업에 의해 참조되는 페이지 또한 고려하였다. 그리고, NVRAM에 저장되는 쓰기 작업에 의해 참조된 페이지를 효율적으로 관리하여 낸드 플래시 메모리에서 발생하는 삭제 연산의 횟수를 감소시켜 SSD의 수명을 연장하였다. 우리는 실험을 통해 제안하는 쓰기 버퍼 알고리즘이 버퍼 적중률을 최대 116.51% 향상시켰으며, 낸드 플래시 메모리에서의 삭제 연산의 횟수를 최대 56.66% 감소시킬 수 있었다.

• 약학회지
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• 제51권6호
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• pp.409-414
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• 2007

Acetylcholinesterase (AChE) plays a role in the progression of Alzheimer's disease (AD). In this study, we examined the improving effect of L-theanine, a major amino acid in Japanese green tea (Camellia sinensis) on the scopolamine (1 mg/kg/mouse)-induced memory dysfunction in mice. Treatment with L-theanine (2, 4 mg/kg/mouse p.o.) in the drinking water for 7 days reversed the scopolamine-induced latency time and distance in the water maze test, latency time in the passive avoidance test, and inhibited AChE activity. This study suggests that L-theanine may be a useful agent for prevention of progression of AD.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 ITC-CSCC -2
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• pp.715-718
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• 2000

Although shared memory parallel programs are designed to be deterministic both in their final results and intermediate states, the races that occur when different processes access a common memory location in an order not guaranteed by synchronization could result in unintended non-deterministic executions of the program. So, Detecting races, particularly first data races, is important for debugging explicit shared memory parallel programs. It is possible that all data races reported by other on-the-fly algorithms would disappear once the first races were removed. To detect races parallel programs with nested loops and inter-thread coordination, it must guarantee the order of synchronization operations in an execution instance. In this paper, we propose an improved restructuring method that guarantee ordering execution instance and preserve the semantics of original program. This method requires O(np) time and (s + up) space, where n is the number of total operations, s is the number of synchronization operations and p is the number of parallelism in the execution. Also, this method makes on-the-fly detection of parallel program with nested loops and inter-thread coordination more easily in space and time complexity.

• 한국진공학회지
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• 제22권3호
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• pp.131-137
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• 2013

본 연구에서는 유기소자의 절연박막을 습식 공정이 아닌 건식 공정인 플라즈마 중합법을 이용하여 Styrene 유기물을 사용하여 절연박막을 제작하였다. 안정적인 플라즈마 형성을 위해 버블러와 써큐레이터를 활용하여 정량적인 모노머 주입을 가능하게 하였다. 본 연구에서는 플라즈마 중합된 Styrene 박막을 30, 60 nm 터널링층으로 활용하였고, Styrene 절연층의 두께를 430 nm, Au 메모리층의 두께를 7 nm, 활성층의 두께를 40 nm, 소스와 드레인 전극의 두께를 50 nm로 유기 메모리 소자를 제작하여 특성을 평가하였다. 40/-40 V의 double sweep시 45 V의 히스테리시스 전압을 얻을 수 있었고, 이는 MMA를 터널링층으로 활용한 유기 메모리 소자의 히스테리시스 전압이 27 V인 것과 비교하였을 때 60% 상승한 효과로 히스테리시스 전압이 18 V 이상 높은 결과이다. 이와 같은 결과로부터 플라즈마 중합된 Styrene 유기 박막의 높은 전하 포집 특성을 활용하여 전체층을 유기 재료로 제작한 유연한 메모리 소자의 응용 가능성을 기대한다.

• 대한본초학회지
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• 제22권2호
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• pp.137-146
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• 2007

Objectives : Investigation of the anitstress effects of Lycii Radicis Cortex. Methods : Behavior was measured in PAT and FST after applying stress to rats. Also, TH expression-degree in the regions of VTA and LC was measured, respectively. Results : The memory was improved in the LH 50mg/kg treated group in the passive avoidance test(P<0.01). The duration of immobility in the forced swimming test was significantly decreased in the LR 50mg/kg and 400mg/kg treated groups(P<0.0l). Stress-induced TH increases were meaningfully suppressed in the LR 100mg/kg and 400mg/kg treated group(P<0.001). Conclusion : Lycii Radicis Cortes has the effect of memory improving and antidepressant.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.187-190
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• 2005

There have been many studies to improve the performance of a database system focused on modifying data structure, data partitioning, and materializing strategy. The main contribution of this study is to propose a new alternative towards improving database performance by designing single table schema or processing queries virtually in main memory space. Material Requirement Planning(MRP) part explosion process has shown almost 2 times shorter under DB schema we suggested, and even more than 10 times shorter when separating and filtering policy of DB archiving process are assumed. Several experimental results are shown to illustrate the excellence of our solution.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 추계종합학술대회
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• pp.768-771
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• 2007

낸드 플래시 메모리는 최근 많은 디지털 기기에서 사용되고 있으며 그 용량과 성능면에서의 발전이 급격이 이루어지고 있다. 낸드 플래시 메모리는 읽고 쓰기 회수에 제한이 있어 이 수명이 다하면 데이터의 신뢰성을 보장하기 어렵다. 이 때문에 낸드 플래시 데이터의 오류를 검출하는 ECC(Error Correction Code) 알고리즘의 적용이 필수적이다. 기존에는 ECC 알고리즘을 논리 게이트로 구현하였으나 본 논문에서는 룩업 테이블 방식을 사용하여 신뢰성과 데이터 처리 시간을 향상시키고자 한다.

• 열처리공학회지
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• 제17권6호
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• pp.342-345
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• 2004

In this work, a new method of measuring volume fraction of deformation-induced ${\varepsilon}$ martensite is proposed using endothermic heat on reverse transformation. As grain size increases, the amount of ${\varepsilon}$ martensite forming on cooling increases. However, with a decrease in grain size, more ${\varepsilon}$ is induced by deformation, improving shape memory effect.