• Korean Journal of Clinical Pharmacy
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• v.32 no.3
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• pp.215-225
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• 2022

Background: Patients with hematologic cancers have a risk of drug-related problems (DRPs) from medications associated with chemotherapy and supportive care. Although the role of oncology pharmacists has been widely documented in the literature, few studies have reported its impact on cost reduction. This study aimed to describe the activities of oncology pharmacists with respect to hematologic diseases and evaluate the associated cost avoidance. Methods: From January to July 2021, patients admitted to the department of hemato-oncology at Seoul National University, Bundang Hospital were studied. The activities of oncology pharmacists were reported by DRP type following the Pharmaceutical Care Network version 9.1 guidelines, and the acceptance rate was calculated. The avoided cost was estimated based on the cost of the pharmacy intervention, pharmacist manpower, and prescriptions associated with the intervention. Results: Pharmacists intervened in 584 prescriptions from 208 patients during the study period. The most prevalent DRP was "adverse drug event (possibly) occurring" (32.4%), followed by "effect of drug treatment not optimal" (28.6%). "Drug selection" (42.5%) and "dose selection" (30.3%) were the most common causes of DRPs. The acceptance rate of the interventions was 97.1%. The total avoidance cost was KRW 149,468,321; the net profit of the avoidance cost, excluding labor costs, was KRW 121,051,690; and the estimated cost saving was KRW 37,223,748. Conclusion: Oncology pharmacists identified and resolved various types of DRPs from prescriptions for patients with hematologic disease, by reviewing the prescriptions. Their clinical service contributed to enhanced patient safety and the avoidance of associated costs.

• PNF and Movement
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• v.20 no.2
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• pp.189-201
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• 2022

Purpose: The purpose of this study was to investigate the effect of McConnell taping and Kinesio taping on pain and lower extremity joint angles when patients with patellofemoral pain syndrome (PFPS) ascend stairs. Methods: Fifty young adults who were experiencing anterior knee pain due to PFPS were selected as participants. Then, 25 patients were randomly assigned to the McConnell taping group and 25 to the Kinesio taping group. Pain and lower extremity joint angle were measured while ascending stairs before and after the intervention. A paired t-test was performed to evaluate the amount of change in the parameter values after the intervention within the groups, and an independent t-test was used to compare the results of the groups. Results: In the within-group comparisons, a statistically significant difference was found in both groups between the anterior knee pain scale scores recorded before and after the intervention (p < 0.05). A statistically significant difference was also found between the groups (p < 0.05). Comparison of the lower extremity joint angles at initial contact, loading response, terminal stance, and pre-swing within the groups showed that there were statistically significant differences in the hip, knee flexion, abduction, lateral rotation, and dorsiflexion angles in both the McConnell and Kinesio taping groups (p < 0.05). There was also a statistically significant difference in all angles between the groups during the following events (p < 0.05): (1) at initial contact, (2) at loading response (except hip flexion angle), (3) at terminal stance (except hip flexion and lateral rotation angles), and (4) at pre-swing (except hip, knee abduction, and inversion angles). Conclusion: McConnell taping and Kinesio taping both effectively improved the occurrence of knee pain and the lower extremity joint angles during stair ascent in patients with PFPS. However, McConnell taping had a significant impact on pain reduction and lower extremity joint angles compared to Kinesio taping.

• Journal of the Korean Association of Geographic Information Studies
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• v.26 no.2
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• pp.42-54
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• 2023

The population is concentrated in the metropolitan areas in Korea, and low-density residential areas are transforming into high density residential areas through redevelopment to meet this demand. However, large-scale redevelopment in a short period of time has a negative impact on the urban climate, such as generating a heat island effect due to the reduction of urban green areas. In this study, the change in surface temperature from 2013 to 2022 in the redevelpment areas of Godeok-dong and Dunchon-dong, Gangdong-gu, Seoul, was analyzed using Landsat 8 satellite images. In the Godeok-dong area, the difference in surface temperature was analyzed for the target redevelopment area, forest area, mixed forest and urban area, and low density residential area. In the Dunchon-dong area, the difference in surface temperature was analyzed for the target redevelopment area, forest area, and low density residential area. The difference in surface temperature was analyzed through multiple regression analysis conducted yearly over the three different stages in redevelopment period. The results from the multiple regression analysis show that in both areas, the land surface temperature of target redevelopment area was higher than that of the forest area and lower than low density residential area. It can be seen that these results occurred because the low-density residential area in Godeok-dong and Dunchon-dong had a lower green area ratio and a higher building-to-land ratio than the target redevelopment area. The results of this study suggest that even if low-density residential areas are transforming into high-density areas, adjusting the management of green areas and building-to-land ratio can contribute to lessen urban heat island effect.

• Environmental and Resource Economics Review
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• v.31 no.4
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• pp.777-799
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• 2022

This study examined the latest EU regulatory strengthening trends for refrigerant gases with very large global warming potential (GWP) and derived implications for carbon neutrality. The European Commission recently unveiled an amendment that significantly strengthens the F-gas Regulation. This study presented the meaning of the main contents related to refrigerants in the amendment by comparing them with the current regulations. The main contents of the amendment include drastically reducing the maximum amount of HFCs that can be placed on the market, strengthening regulations related to HFCs allocation, adding products and equipment that use high GWP refrigerants, adding regulated F-gas and updating the GWP of existing gases, and other stricter regulatory designs. This movement of the EU will affect the policy stance of advanced countries such as the United States and Japan, and Korea's policy will also be further strengthened. Therefore, it will be inevitable for related industries to change to next-generation refrigerant gas. Meanwhile, this study also analyzed the latest policy trends related to per- and polyfluoralkyl substances (PFAS) regulation, which were not noted in previsou studies on refrigerants and F-gas. If PFAS's registration of REACH restricted substances, which are being promoted by five European countries, is made, it will have a very big impact on the industry regarding refrigerant gas. In addition, it will be inevitable to thoroughly review each country's greenhouse gas reduction strategies related to F-gas materials, including refrigerants.

• Korean Chemical Engineering Research
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• v.61 no.2
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• pp.258-264
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• 2023

The greenhouse gas (GHG) emission assessment of kenaf pellet, produced from locally generated kenaf residues in South Korea, has been studied based on the EU RED-II methodology for calculating GHG impact of biomass fuels. Based on the production pathway of kenaf residue pellet and emission coefficients from EU JRC report, the life cycle GHG emission of kenaf residue pellet is assessed as 3.0 gCO₂eq/MJ_pellet and the life cycle GHG emission of electricity generated from kenaf residue pellet is assessed as 11.9 gCO₂eq/MJ when electrical efficiency of final conversion is 25%. The potential GHG emission reduction of electricity produced from kenaf pellet is 90.3% compared to the domestic electricity emission factor 42.8 kgCO₂eq/MWh. Also, the electricity produced from kenaf pellet can reduce at least 59.6% of GHG emission compared to the electricity produced from imported wood pellets.

• Journal of the Korean Applied Science and Technology
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• v.40 no.2
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• pp.290-300
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• 2023

This study was understood the risk mechanism of falls in the elderly and reviewed previous research data to see if the principle of Pilates rehabilitation exercise could have a positive effect on balance ability and postural stabilization in the elderly, and the purpose of this study is to present literature-based data on the fall prevention effect of rehabilitation Pilates exercise. First, the rehabilitation Pilates exercise makes it available for strengthening the center of the body to stabilize the spine and pelvis and stimulates the nerve root, thereby having an effect on the balance and the joint stabilization. Second, a proprioceptive sensory impairment and a musculoskeletal degenerative disease due to aging increase the loss of balance ability and the instability in posture maintenance, thereby coming to raise the risk of a fall damage caused by the difficulty in performing motor functions and by the gait disturbance. Third, the rehabilitation Pilates exercise leads to improving the core muscle strength in older adults, resulting in being capable of expecting the betterment in the balance and the reaction time motor function. And there is a positive impact on the improvement in body imbalance and on the stability in movement involved in the fall prevention, resulting in being able to suggest the possibility of likely contributing to a reduction in a fall risk rate. In conclusion, the rehabilitation Pilates as the elderly exercise program showed effects on the improvement in the body's muscular strength, on the upgrade in a sense of balance, and on the stabilization of core. Thus, it was considered to diminish the risk factors for a fall damage caused by musculoskeletal degeneration and to be capable of preventing a serious disorder of activity due to a chronic senile disease.

• Journal of Korean Medicine for Obesity Research
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• v.23 no.1
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• pp.1-9
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• 2023

Objectives: Noni fruit juice (NFJ) is liquor extracted from Morinda citrifolia (noni) fruit and has been used as an herbal remedy in many countries. However, the NFJ's anti-adipogenic and anti-inflammatory effects on adipocytes are poorly understood. The purpose of this study was to explore the commercially standardized NFJ effects on lipid accumulation throughout 3T3-L1 preadipocytes differentiation and interleukin-1β (IL-1β)-mediated inducible nitric oxide synthase (iNOS) expression in 3T3-L1 preadipocytes. Methods: Cellular lipid accumulation and triglyceride (TG) content in differentiating 3T3-L1 preadipocytes were assessed subsequently via the Oil Red O staining and AdipoRed assay. MTS assay was used to examine NFJ cytotoxicity in (differentiating) 3T3-L1 preadipocytes. Immunoblotting and reverse transcriptase polymerase chain reaction analysis were used to measure the expression levels of target protein and mRNA in (differentiating) 3T3-L1 preadipocytes, respectively. Results: NFJ treatment at 150 μL/mL led to a substantial reduction of fat accumulation and TG content during 3T3-L1 adipogenesis with no discernable impact on the cell viability. Of note, while NFJ treatment (150 μL/mL) largely inhibited the CCAAT/enhancer-binding protein-α (C/EBP-α) and peroxisome proliferator-activated receptor-β (PPAR-β) protein expressions, it did not influence PPAR-γ in differentiating 3T3-L1 preadipocytes. Of interest, treatment with IL-1β at 20 ng/mL for 4 hours elicited in firm induction of iNOS mRNA expression in 3T3-L1 preadipocytes. However, NFJ treatment at 100 or 200 μL/mL greatly attenuated the IL-1β-induced iNOS mRNA expression in 3T3-L1 preadipocytes. Conclusions: NFJ has anti-adipogenic and anti-inflammatory effects on (differentiating) 3T3-L1 preadipocytes which are in part intervened via control of the expression of C/EBP-α, PPAR-β, and iNOS.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.19 no.1
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• pp.157-174
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• 2008

Information Technology is making a lot of changes in the library. Especially the library computerization made the business of librarians convenient and made an impact in outsourcing and job reduction. The number of library users is decreasing because they can find information easily in the internet instead of library. But librarians are suspended in traditional business; they are not carrying out new role in changed environment. So, their identity is shaken. If a job does not have their identity, the job can not but disappears. This paper wished to find the identity of librarians in digital environment. For research the author examined literatures about new role of librarians and compared with librarian's opinions. To collect librarian's opinions, the author took e-mail survey to librarians who are working more than 20 years at libraries. Questionnaire consists of open-ended question. As a result, librarians are feeling their professional rewarding in public service. But they do not have much opportunity to service as professional. In some case librarians have opportunity to secure their expert area in reading education, information literacy and computer program teaching. This means the information education and medium education. The information education means to and necessary information. The medium education means to approach at information. The ability that can utilize information and medium is very important in lifelong learning society. Librarians can achieve the role of information and medium education. Librarians can find their identity in information and medium education which make users as intellectual person.

• Korean Journal of Ichthyology
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• v.34 no.4
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• pp.262-269
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• 2022

A distribution survey was conducted from 2018 to 2020 to evaluate the distribution status, habitat characteristics, and extinction threat of the short ninespine stickleback Pungitius kaibarae (Gasterosteidae). Literature reports of P. kaibarae distribution have been sorted by each period, 1980~1996, 1997~2005, and 2007~2017, and the samples were collected in 32, 43, and 64 stations for each period. Among the 75 streams and 193 sampling sites investigated during the study period, 1,400 P. kaibarae individuals were collected from 26 streams at 39 sites. The main habitat of P. kaibarae was downstream or brackish water zones with a low altitude, slow water velocity, and many aquatic plants. The main reasons for the decline in population size were assumed to be drought and flood, river work for flood restoration and river maintenance, bridges construction, and predation by the exotic fish species Micropterus salmoides. Previous evidence reported a 42.6% reduction in occupancy within 10 years, a decline in habitat quality, and the spread and impact of the exotic fish species Micropterus salmoides. Therefore, P. kaibarae is now considered a Vulnerable (VU A2ace) species based on the IUCN Red List categories and criteria. Therefore, P. kaibarae should be redesignated as an endangered species by the Ministry of Environment and systematically managed.

• Smart Media Journal
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• v.12 no.5
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• pp.36-45
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• 2023

Recently, in digital agriculture, the types and utilization of greenhouses based on IoT are spreading, and greenhouses are being modernized, enlarged, and even factoryized using smart technology. However, a specific standardization plan has not been proposed according to the equipment for data collection in the smart greenhouse and the size or shape of the greenhouse. In other words, there is a lack of standard data for facility equipment, such as the type and number of sensors and equipment according to the size of the greenhouse, the type of greenhouse construction film and materials suitable for crops and carbon neutrality. Therefore, in this study, the suitability of the implementation, installation and quantity of IoT equipment for data collection was tested, and some standard technologies were presented through the implementation of data collection and communication methods. In addition, impact strength, tensile, tear, elongation, light transmittance, and lifespan issues for PE, PVC, and EVA, which account for about 90% of existing greenhouses, were presented, and the shape, size, and environmental problems of greenhouses made of films were presented. presented in the text. In this research paper, a standardized carbon-neutral modular smart greenhouse using nano-material film was implemented as a solution to environmental problems such as greenhouse size, farm crop type, greenhouse lifespan, and film, and its performance with existing greenhouses was analyzed and presented. Through this, we propose a modularized greenhouse that can be expanded or reduced freely without distinction in the size of the greenhouse or the shape of farmhouse crops, and the lifespan is extended and standardized. Finally, the average characteristics of greenhouses using existing PE, PVC, and EVA films and the characteristics of greenhouses using new carbon-neutral nanomaterials are compared and reviewed, and a plan to implement an expandable IoT greenhouse that supports carbon neutrality is proposed.