• Title/Summary/Keyword: ITS II

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Mission Design for a Lunar Orbiter Launched by KSLV-II (한국형발사체를 사용한 달궤도선의 임무 설계)

  • Song, Eun-Jung;Park, Chang-Su;Cho, Sang-Bum;Roh, Woong-Rae
    • Aerospace Engineering and Technology
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    • v.8 no.1
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    • pp.108-116
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    • 2009
  • This paper considers the trajectory design problem for a lunar orbiter when launched by KSLV-II. KSLV-II puts its kick motor stage and lunar orbiter into a low earth orbit, and then the kick motor stage performed the translunar injection. To simulate more realistic situations, TLI (Trans-Lunar Injection) and LOI (Lunar Orbit Injection) maneuvers are modeled as finite burns. The feasibility of the lunar mission by KSLV-II are confirmed by the numerical results that show the reasonable required-velocity and propellant usage.

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Catalytic Hydrolysis of Phosphate Diesters as DNA Model with Tetranuclear Nickle (II) Complex

  • Sung, Nack-Do;Kim, Tae-Young
    • Journal of Applied Biological Chemistry
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    • v.49 no.3
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    • pp.86-89
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    • 2006
  • The novel tetranuclear nickel (II) complex is a high rate accelerator in promoting hydrolysis of phosphate diesters. Nickel-bound bis-nitrophenyl phosphate (BNPP) can be $10^4$ times more reactive than the unbound BNPP. The large rate of enhancements by the complex slightly under basic condition has shown high catalytic activity in phosphate diester cleavage. The bell-shaped pH-rate profile indicated that the nickel-oxide form of the tetranuclear complex or its kinetic equivalent was the active species for cleaving BNPP. The catalytic hydrolysis between tetranuclear nickel (II) complex and phosphate diester proceeds via the formation of bidentate coordination of the anionic phosphate to the Ni (II) atom. This reveals that the complex has the possibility as artificial nuclease.

Anti-hepatotoxic Activity of Icariside II, a Constituent of Epimedium koreanum

  • Cho, Nam-Jin;Sung, Sang-Hyun;Lee, Heum-Sook;Jeon, Mee-Hee;Kim, Young-Choong
    • Archives of Pharmacal Research
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    • v.18 no.4
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    • pp.289-292
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    • 1995
  • Icariside II, a flavonol glycoside, was isolated from the aerial part of Epimedium Koreanum Nakai by the anti-hepatotoxic acitivity guided fractionation technique employing $CCl_4-in-toxicated$ primary cultured rat hepatocytes as an assay system. Its anti-hepatotoxic activity was evaluated by measuring activity of glutamic pyruvic transaminase released from the $CCl_4-in-toxicated$ primary cultured rat hapatocytes. Icariside II significantly reduced the activity of glutamic pyruvic transaminase released from the $CCl_4-in-toxicated$ primary cultured rat hepatocytes and resulted in 78% recovery of the toxicity at the concentration of $200{\;}\mu\textrm{m}$. The anti-hepatotoxic activity of icariside II on the $CCl_4-in-toxicated$ primary cultured rat hepatocytes was as potent as that of silybin.

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Origin of the Multiple Type II Solar Radio Bursts Observed on December 31 2007

  • Cho, Kyung-Suk;Bong, Su-Chan;Kim, Yeon-Han;Kwon, Ryun-Young;Park, Geun-Seok;Moon, Yong-Jae;Park, Young-Deuk
    • Bulletin of the Korean Space Science Society
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    • 2009.10a
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    • pp.37.1-37.1
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    • 2009
  • Solar type II radio burst is regarded as a signature of coronal shock. However its association with coronal mass ejections (CMEs)-driven shock and/or flare blast waves remains controversial. On December 31 2007, SOHO/LASCO and STEREO/COR observed a CME that occurred on the east limb of the Sun. Meanwhile, two type II bursts were observed sequently by KASI/E-Callisto and the Culgoora radio observatory during the CME apparence time. In this study, we estimate kinematics of the two coronal shocks from dynamic spectrum of the multiple type II bursts and compare with the kinematics of the CME derived from the space observations. An origin of the multiple type II bursts is inspected and discussed briefly.

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Easy, Efficient Class II composite resin restoration technique (쉽고 효율적인 클래스 II 복합레진수복테크닉)

  • Lee, Changhoon
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.27 no.2
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    • pp.66-74
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    • 2018
  • Composite resin restoration on class II cavities is a challenging procedure since it is tough to replicate proper contact, the natural shape of the tooth, etc. Moreover, it is not familiar with the procedure and tools for this specific situation, neither. Nowadays the patients, however, request more and more composite restorations which are relatively quick and more esthetic. In this case report, the class II composite resin restoration procedure is illustrated step by step. Every step must be considered its final consequence thoroughly. In this approach, we can minimize the finishing procedure and save our effort and time.

Localization of Angiotensin II in Korean Bovine Follicles and Its Effects on IVM/IVF of Oocytes (한우 난소 내 Angiotensin II의 분포와 이의 첨가가 체외성숙 및 수정에 미치는 영향에 관한 연구)

  • Quen, J. H.;M. H. Lee;S. K. Kim
    • Reproductive and Developmental Biology
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    • v.28 no.1
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    • pp.59-63
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    • 2004
  • 1. The concentrations of Ang. II were 7.20.91 ${\times}$ $10^3$ , 3.80.34 ${\times}$ $10^3$, 3.50.30 ${\times}$ $10^3$, 2.80.22 ${\times}$ $10^3$ pg/ml in bovine follicular fluids from 1∼3 mm, 3∼5 mm, 5∼7 mm and 8∼10 m follicles, respectively. The concentrations of Ang. II decreased in follicular fluids from large follicles. 2. When oocytes were cultured in media containing various concentrations of Ang. II, a higher proportion of oocytes developed to MII stage in medium with 100 ng/ml (79.5%) Ang II compare to that without Ang. II (58.8%). When oocytes from different sizes of follicles were separately cultured in media containing 100 ng/ml Ang. II, maturation rates were higher in oocytes from small and medium follicles those from controls. 3. GSH content in oocytes cultured for 24 hrs in TCM-199 medium containing 10 and 100 ng/ml of Ang. II was also higher than that of oocytes cultured in medium containing 0 or 10 ng/ml Ang. II. When oocytes were cultured in media containing 0, 10, 100, 1,000 ng/ml of Ang. II, the concentrations of GSH were 5.1M, 5.5M, 7.2M, 8.7M, respectively. 4. When oocytes were cultured in media containing various concentrations of 10, 100, 1,000 ng/ml Ang. II, in vitro maturation and developmental rates were 84.0%, 90.0%, 78.0% and 28.0%, 36.0%, 20.0%, respectively. When oocytes were cultured with an addition of Ang. II in media, in vitro maturation rates higher than that of their controls (76.0%).

Preparation of a Liquid Membrance Type Ion-Selective Electrode and Its Application to the Potentiometric Titration (액체막형 구리이온 선택성 전극의 제작과 전위차적정에의 응용)

  • Heung Lark Lee;Seung Tae Yang
    • Journal of the Korean Chemical Society
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    • v.29 no.2
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    • pp.137-143
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    • 1985
  • Construction of a liquid membrane type of cupric ion selective electrode and its application to the potentiometric titration have been studied. A liquid ion-exchange membrance was prepared by extracting Cu(II) in aqueous solution into 1-(2-pyridylazo)-2-naphthol/nitrobenzene. A Ag/AgCl internal reference electrode was dipped into the aqueous reference solution of $1.00 {\times} 10^{-3}M\;Cu(NO_3)_2$ buffered with HAc-NaAc buffer solution, which was in contact with the nitrobenzene extract. The electrode showed the nernstian response to Cu(II) in the concentration range from $1.00{\times} 10^{-6}$ to $1.00{\times} 10^{-3}$M. The most suitable ion-exchanger concentration in the liquid membrane was $1.00{\times} 10^{-4}$M. The selectivity coefficients of the electrode for the various metal cations were investigated. The electrode was applied to the potentiometric titration of Cu(II) with EDTA.

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SH 2-128, AN H II AND STAR FORMING REGION IN AN UNLIKELY PLACE

  • BOHIGAS JOAQUIN;TAPIA MAURICIO
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.285-288
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    • 2004
  • Near-infrared imaging photometry supplemented by optical spectroscopy and narrow-band imaging of the H II region Sh 2-128 and its environment are presented. This region contains a developed H II region and the neighboring compact H II region S 128N associated with a pair of water maser sources. Midway between these, the core of a CO cloud is located. The principal ionizing source of Sh 2-128 is an 07 star close to its center. A new spectroscopic distance of 9.4 kpc is derived, very similar to the kinematic distance to the nebula. This implies a galactocentric distance of 13.5 kpc and z = 550 pc. The region is optically thin with abundances close to those predicted by galactocentric gradients. The $JHK_s$ images show that S 128N contains several infrared point sources and nebular emission knots with large near-infrared excesses. One of the three red Ks knots coincides with the compact H II region. A few of the infrared-excess objects are close to known mid- and far-infrared emission peaks. Star counts in J and $K_s$ show the presence of a small cluster of B-type stars, mainly associated with S 128N. The $JHK_s$ photometric properties together with the characteristics of the other objects in the vicinity suggest that Sh 2-128 and S 128N constitute a single complex formed from the same molecular cloud, with ages ${\~}10^6$ and < $3 {\times} 10^5$ years respectively. No molecular hydrogen emission was detected at 2.12 ${\mu}m$. The origin of this remote star forming region is an open problem.

The Implementation of uClinux Device Driver of Nios II Embedded Processor System for Multimedia Application (멀티미디어 응용을 위한 Nios II 임베디드 프로세서 시스템의 uClinux 디바이스 드라이버 구현)

  • Kim, Dong-Jin;Park, Young-Seak
    • Journal of the Institute of Convergence Signal Processing
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    • v.10 no.4
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    • pp.245-255
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    • 2009
  • Recently, embedded processor systems have been widely used in the field of information communication devices and increased its use range and influence. The embedded systems are offered variety of functions, and its operating systems have been developed to make them easy to repair and maintain. Especially embedded linux is very cheap and provide a lot of equipment drivers. Also we can set up our own system because the source code is opened. In this paper, we describe the implementation of Touch panel and TFT-LCD device driver that are widely used for multimedia application. We designed the system hardware by using Altera Nios II embedded system. And we implemented the device drivers of frame buffer, touch panel and i2s based on uClinux for multimedia application, and tested actual operations of the integrated system.

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Activating transcription factor 4 aggravates angiotensin II-induced cell dysfunction in human vascular aortic smooth muscle cells via transcriptionally activating fibroblast growth factor 21

  • Tao, Ke;Li, Ming;Gu, Xuefeng;Wang, Ming;Qian, Tianwei;Hu, Lijun;Li, Jiang
    • The Korean Journal of Physiology and Pharmacology
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    • v.26 no.5
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    • pp.347-355
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    • 2022
  • Abdominal aortic aneurysm (AAA) is a life-threatening disorder worldwide. Fibroblast growth factor 21 (FGF21) was shown to display a high level in the plasma of patients with AAA; however, its detailed functions underlying AAA pathogenesis are unclear. An in vitro AAA model was established in human aortic vascular smooth muscle cells (HASMCs) by angiotensin II (Ang-II) stimulation. Cell counting kit-8, wound healing, and Transwell assays were utilized for measuring cell proliferation and migration. RT-qPCR was used for detecting mRNA expression of FGF21 and activating transcription factor 4 (ATF4). Western blotting was utilized for assessing protein levels of FGF21, ATF4, and markers for the contractile phenotype of HASMCs. ChIP and luciferase reporter assays were implemented for identifying the binding relation between AFT4 and FGF21 promoters. FGF21 and ATF4 were both upregulated in Ang-II-treated HASMCs. Knocking down FGF21 attenuated Ang-II-induced proliferation, migration, and phenotype switch of HASMCs. ATF4 activated FGF21 transcription by binding to its promoter. FGF21 overexpression reversed AFT4 silencing-mediated inhibition of cell proliferation, migration, and phenotype switch. ATF4 transcriptionally upregulates FGF21 to promote the proliferation, migration, and phenotype switch of Ang-II-treated HASMCs.