• Title/Summary/Keyword: IT Complex

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Discrimination between RNAP IIA and IIO in Preinitiation Complex Assembly and Tyrosine Phosphorylation of the Carboxy Terminal Domain

  • Lee, Sang-Soo
    • BMB Reports
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    • v.30 no.5
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    • pp.362-369
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    • 1997
  • Multiple phosphorylation of the carboxy-terminal domain (CTD) of the largest subunit in RNA polymerase II (RNAP II) is thought to play an important role in the transcription cycle. The preinitiation complex in a partially purified complete transcription system suggested that RNA polymerase IIA containing unphosphorylated CTD is involved in complex assembly, whereas RNA polymerase IIO containing Ser and Thr phosphorylated CTD is not involved in preinitiation complex assembly. Recently a minimal transcription system was developed which requires chemically defined minimal components for its transcription: TBP, TFIIB, TFIIF, RNAP II and a supercoiled adenovirus-2 major late promoter (Ad-2 MLP). It would be using interesting to determine the consequence of CTD phosphorylation on preinitiation complex formation using the minimal transcription system. Contrary to the results from the partially purified complete transcription system, both RNA polymerase IIA and IIO are equally recruited in the preinitiation complex formation. The discrepancy may result from the two different assays used to determine complex formation, the use of chemically undefined complete and defined minimal transcription systems. This implicates that some factors in the complete transcription system are involved in the distinction between RNAP IIA and IIO in complex assembly. In addition multiple tyrosine phosphorylation of the CTD of RNAP II was prepared with c-Abl kinase and its recruiting ability in the preinitiation complex was examined. Compare with Ser and Thr phosphorylated RNAP IIO, Tyr phosphorylated RNAP IlOy forms a stable preinitiation complex in both the minimal and complete transcription systems. Based on these results, it seems that tyrosine phosphorylation of the CTD is important in the transcription cycle on the special subset of class-II promoter or has a different role in the transcription process.

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A Study on the Present Condition's Facilities and Program of School Facilities Complex as Public Facilities Complex : Based on the Cases of the Elementary Schools in Seoul (공동체 복합지원시설로서 학교시설의 복합화 시설 및 프로그램 실태에 관한 연구 : 서울시 초등학교시설복합화 사례를 중심으로)

  • Shin, Hwa-Kyoung;Jo, In-Sook;Lee, Joon-Min
    • Journal of Families and Better Life
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    • v.28 no.2
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    • pp.39-50
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    • 2010
  • The aims of this study are to present the basic data of a school facilities complex and to analyze the necessity of a school facilities complex, school facilities characteristics and program characteristics. In the study, there can be found an analysis of the present conditions of the school facilities complex by literature research and the analysis of school facilities characteristics and program characteristics by case study. The results of this study are as follows: First, the elementary school facilities are mixed with the gym, swimming pool, culture center and convenient facility(parking lot). Second, the school facilities complex is not connected with the number of elementary school students. As the number of elementary school students decrease, it is possible to apply the generated surplus space of the school facilities to the community facility. Third, the school facilities complex is not connected to the reliance ratio of local finance. It is necessary for the central government to provide active financial and to build a financial support model. Fourth, most of the time, the entrance of the facility complex is divided from the entrance of the school facility. Fifth, the programs of many school facility complexes are composed of swimming and physical fitness programs.

Development of Real-time QRS-complex Detection Algorithm for Portable ECG Measurement Device (휴대용 심전도 측정장치를 위한 실시간 QRS-complex 검출 알고리즘 개발)

  • An, Hwi;Shim, Hyoung-Jin;Park, Jae-Soon;Lhm, Jong-Tae;Joung, Yeun-Ho
    • Journal of Biomedical Engineering Research
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    • v.43 no.4
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    • pp.280-289
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    • 2022
  • In this paper, we present a QRS-complex detection algorithm to calculate an accurate heartbeat and clearly recognize irregular rhythm from ECG signals. The conventional Pan-Tompkins algorithm brings false QRS detection in the derivative when QRS and noise signals have similar instant variation. The proposed algorithm uses amplitude differences in 7 adjacent samples to detect QRS-complex which has the highest amplitude variation. The calculated amplitude is cubed to dominate QRS-complex and the moving average method is applied to diminish the noise signal's amplitude. Finally, a decision rule with a threshold value is applied to detect accurate QRS-complex. The calculated signals with Pan-Tompkins and proposed algorithms were compared by signal-to-noise ratio to evaluate the noise reduction degree. QRS-complex detection performance was confirmed by sensitivity and the positive predictive value(PPV). Normal ECG, muscle noise ECG, PVC, and atrial fibrillation signals were achieved which were measured from an ECG simulator. The signal-to-noise ratio difference between Pan-Tompkins and the proposed algorithm were 8.1, 8.5, 9.6, and 4.7, respectively. All ratio of the proposed algorithm is higher than the Pan-Tompkins values. It indicates that the proposed algorithm is more robust to noise than the Pan-Tompkins algorithm. The Pan-Tompkins algorithm and the proposed algorithm showed similar sensitivity and PPV at most waveforms. However, with a noisy atrial fibrillation signal, the PPV for QRS-complex has different values, 42% for the Pan-Tompkins algorithm and 100% for the proposed algorithm. It means that the proposed algorithm has superiority for QRS-complex detection in a noisy environment.

A CHARACTERIZATION OF HOROSPHERES AND GEODESIC HYPERSPHERES IN A COMPLEX HYPERBOLIC SPACE IN TERMS OF RICCI TENSORS

  • Ahn, Seong-Soo
    • Bulletin of the Korean Mathematical Society
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    • v.35 no.3
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    • pp.503-514
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    • 1998
  • We want to treat this problem for real hypersurfaces in a complex hyperbolic space $J_n(C)$. Thus it seems to be natural to consider some problems concerned with the estimation of the Ricci tensor for real hypersurfaces in $H_n(C)$. In this paper we will find a new tensorial formula concerned with the Ricci tensor and give it a characterization of horospheres and geodesic hyperspheres in a complex hyperbolic space $H_n(C)$.

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A REMARK ON GENERALIZED COMPLEX ELLIPSOIDS WITH SPHERICAL BOUNDARY POINTS

  • Kodama, Akio
    • Journal of the Korean Mathematical Society
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    • v.37 no.2
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    • pp.285-295
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    • 2000
  • It is well-known that there is no analogue to the Riemann mapping theorem in the higher dimensional case. Therefore, it would be an interesting question to find sufficient conditionsl for domains to be biholomorphically equivalent to the unit bal. In this paper, we investigate this questionin the case where the given domains are generalized complex ellipsoids with spherical boundary points.

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수도권 동북부 지역 물류단지 건설에 관한 연구(양회단지를 중심으로)

  • Kwon Yong-Jang;Kim Hyun-Woong;Yoo Jae-Kyun
    • Proceedings of the KSR Conference
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    • 2004.10a
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    • pp.1652-1661
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    • 2004
  • It is essential to our economy that preserve the cement industry which has contributed to the growth of construction industry. However, it has not been easy to come up with constructing Silo complex in downtown area due to the opposition of residents, and lack of the supply base aroused the troubles in provision of cement. The main objective of this paper lies in making plans for constructing Silo complex and estimating logistics costs affected by the alternative complex.

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A Study on the Mixed Use Complex Design (Mixed Use Complex 디자인에 관한 연구 -업무/상업/문화오락/주거기능 복합의 사례분석을 중심으로-)

  • 이혜진
    • Archives of design research
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    • v.21
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    • pp.207-217
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    • 1997
  • Mixed Use Area (Multifaceted Integration) is getting increasingly demanded since it has several merits such as preventing CBD from being emptied during night time, making daily life comfortable and utilizing the land more efficiently. However, the characteristic of Mixed Use Area -as advantages of it-, which is that it combines residence, retail, office, cultural, entertainment facilities altogether could be regarded as a weakness when it is viewed from each functions' original purposes such as residential and retail areas'. Accordingly, it is needed to do basic research and develop design guidelines of the Mixed Use Area to prepare its another take-off. The purpose of this research is to study theoretical background of Mixed Use Area's birth, understand its status quo by examining examples overseas and presented possible standardized ways of developing it.

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Analysis on Accuracy and Indigenity of Landscape Plants Species in Planting Design and Construction (식재설계 및 시공시 조경수종 사용에 있어서의 정확성과 자생성 분석)

    • Journal of the Korean Institute of Landscape Architecture
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    • v.26 no.2
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    • pp.251-258
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    • 1998
  • The purposes of this study was to investigate accuracy and indigenity of landscape plant species in planting design and construction at housing complex and offer basic data for improving precision of planting construction. The scientific name of landscape plant species was described in planting drawings at only two sites among twelve survey sites. According to analysis on indigenity of plant species in planting drawings, it was found that the component ratio of foreign species was the highest and the component ratio of native species at public housing complex was the lowest. The component ratio of landscape plant species in planting construction was severely differed to that of planting drawings. Also the component ratio of cultivar was higher than that of planting drawings due to planting of sevveral cultivars for one species in planting drawings. In the result of accuracy analysis on landscape plant species in planting construction, it was found that mean ratio of inacccurate species was 33.2% at public housing complex, 29.6% at local company housing complex and 26.4% at nationwide company housing complex. It was found that several cultivars were planted for one species in planting drawings. The representative species which were planted by several cultivars were Camellia japonica, Rododendron spp., Prunus spp. and Magnolia spp. and so on. In order to promote the precision and speciality of planting design and construction, scientific and cultivar name of plants should be described in planting drawings.

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A Study on the Characteristic Analysis of Housing Complex planning by Regional Characteristic (지역성을 고려한 주거단지계획의 특성분석을 위한 사래연구 -대구광역시 'U 대회 선수촌 단지'를 중심으로 -)

  • Seo Ji-Eun;Park Eui-Jeong
    • Journal of the Korean housing association
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    • v.17 no.3
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    • pp.31-40
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    • 2006
  • The purpose of this study is to grasp the present state of a outdoor space planning and to analysis plan characteristics in based on regional characteristics in Housing complex plan. The analysis result of this study is as follows : first, we know that the right of regional characteristics is appearing variously every research workers. also an analysis about regional characteristics that should be considered in housing complex plan was insufficient. Second, regional characteristics can be classified into 5 factors. These are classified as a context of location, city link, life atmosphere, needs of locals and creation of image. Third, it has originality against other housing complex to graft items connected with 'U contest' on outdoor space planning. Also, it has affirmatively effected on image of Buk-gu and recognition of Dong beyn-dong and Seo beyn-dong. It is get out of the uniform design by a planning based on land and surrounding environment in arrangement and forms. Also residents have the satisfaction and pride in arrangement considering the climate of a region and security of the green space.