• Genomics & Informatics
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• v.4 no.1
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• pp.45-47
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• 2006

D2GSNP is a web-based server for the selection of single nucleotide polymorph isms (SNPs) within genes related to human diseases. The D2GSNP is based on a relational database created by downloading and parsing OMIM, GAD, and dbSNP, and merging it with positional information of UCSC Golden Path. Totally our server provides 5,142 and 1,932 non-redundant disease genes from OMIM and GAD, respectively. With the D2GSNP web interface, users can select SNPs within genes responding to certain diseases and get their flanking sequences for further genotyping experiments such as association studies.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.3
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• pp.825-829
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• 2004

This study was carried out to differentiate the origins of Astragalus membranaceus Bunge and A. membranaceus Bunge var. mogholicus Nakai. To identify the variation of the RAPD patterns between domestic and foreign Astragalus species, 40 random primers were applied to ten accessions of A. membranaceus and six accessions of A. membranaceus var. mogholicus genomic DNA, respectively, Ten primers of 40 primers could be used to discriminate the origins and 33 polymorph isms among 44 scored DNA fragments (33 fragments are specific for A. membranaceus and A. membranaceus var. mogholicus) were generated using these primers, 75.0 % of which were polymorphic. Especially, three primers of ten primers, OPA17, OPA11 and OPB11, were useful to differentiate between domestic and foreign Astragalus species. RAPD data from the 10 primers were used for cluster analysis and cluster analysis of RAPD markers showed that the two groups are distinct genetically. Consequently, RAPD analysis was a useful method to discriminate between A. membranaceus and A. membranaceus var. mogholicus.

• Journal of Information Technology Services
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• v.15 no.3
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• pp.33-50
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• 2016

In a dynamic IT environment, employees often utilize external IT resources to work more efficiently and flexibly. However, the use of external IT resources beyond its control may cause difficulties in the company. This is known as "Shadow IT." In spite of efficiency gains or cost savings, Shadow IT presents problems for companies such as the outflow of enterprise data. To address these problems, appropriate measures are required to maintain a balance between flexibility and control. Therefore, in this study, we developed a new information security management system called AIIMS (Advanced IT service & Information security Management System) and the Shadow IT Evaluation Model. The proposed model reflects a Shadow IT's attributes such as innovativeness, effectiveness, and ripple effect. AIIMS consists of five fields: current analysis; Shadow IT management plans; management process; education and training; and internal audit. There are additional management items and sub-items within these five fields. Using AIIMS, we expect to not only mitigate the potential risks of Shadow IT but also create successful business outcomes. Now is the time to draw to the Light in the Shadow IT.

• Parasites, Hosts and Diseases
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• v.45 no.1 s.141
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• pp.59-63
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• 2007

Merozoite surface protein-1(MSP-1) and merozoite surface protein-2(MSP-2) were used to develop vaccines and to investigate the genetic diversity in Plasmodium falciparum malaria in Iran. Nested polymerase chain reaction amplification was used to determine polymorph isms of block 2 of the MSP-1 and the central domain of MSP-2 genes. A total of 67 microscopically positive P. falciparum infected individuals from a major endemic region, southeast Iran, were included in this trial. Nine alleles of MSP-1 and 11 alleles of MSP-2 were identified. The results showed that amplified product from these surface antigen genes varied in size and there was specific pattern for each isolate. Besides, regarding this pattern, 23 multiple infections with at least 2 alleles were observed. While the endemic regions of malaria in Iran is classified in low to moderate group, but extensive polymorphism was observed for each marker and the MSP-2 central repeat was the most diverse that could be considered in designing malaria vaccine.

• Toxicological Research
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• v.22 no.2
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• pp.69-74
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• 2006

Hypertension leads to major health problems in many industrialized countries, and multiple etiologic factors are involved in the pathogenesis of this disorder. The genetic components of the natriuretic peptide system might be involved in the pathogenesis of hypertension. In this regard, the atrial natriuretic peptide (ANP) gene has been proposed as a candidate hypertension gene. Therefore, we investigated the G1837A and C-664G polymorphisms of the ANP gene in 143 Korean normotensives and 118 hypertensives. There were no significant differences in the genotype and allele frequencies between the two groups. Although the frequencies in each of these polymorph isms were not significantly different between normotensives and hypertensives, our results provide additional ethnic information for linkage analysis and associated studies of this disorder with cardiovascular disease.

• Fisheries and Aquatic Sciences
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• v.11 no.3
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• pp.133-139
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• 2008

Molecular techniques, including restriction fragment length polymorphism(RFLP) and polymerase chain reaction-single strand conformational polymorph isms(PCR-SSCP), were developed to identify salted, dried threadfin(Eleutheronema tetradactylum) and white herring(Ilisha elongata) fish. Using PCR with universal primers, conserved 367-bp fragments of the cytochrome b gene were amplified from fresh fish samples and sequenced. The sequences were then searched for specific restriction sites. The digestion of the PCR products with the endonucleases AvaI, FokI, MboII, and MspI generated RFLP, which was used to identify the commercial products. Similarly, the amplified PCR-SSCP products were developed and the products tested. Overall, similar patterns were found in the majority of the fresh and processed products. Based on the results, both RFLP and PCR-SSCP were useful in determining and validating the authenticity of the fish species used to prepare the commercial salted, dried products. A similar approach can be applied to other species.

• Convergence Security Journal
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• v.16 no.4
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• pp.53-61
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• 2016

A number of countries have been developing and implementing national cybersecurity strategy to prevent damages caused by cyber threats and to minimize damages when they happened. However, there are a lot of differences and disparities in respective strategies with their own background and needs. A vulnerability in some places can be a global problem, so various guidelines have been developed by relevant organizations including international organizations to support the establishment of national cybersecurity strategies and improvement of them. In this paper, with analysis on the guidelines for the establishment of national cybersecurity strategies, reference model consisting of common elements of strategies was suggested. And several recommendations for the improvement measures for Korean national cybersecurity strategies were explained with a comparison of the reference model.

• Convergence Security Journal
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• v.16 no.4
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• pp.3-15
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• 2016

Business data means data of all the documents and electronically generated on / off-line form, storage, use, and transfer the company work process. Business, organization, sales, marketing, means any data related to shipping. Many companies are investing in privacy. But not so for business data. In most companies, secret, confidential rating already exists, the basis is insufficient to establish that decisions can be analyzed in detail to reflect the actual business data in use. In this paper we want to present the criteria that can offer ways to design your business data decision matrix to establish the qualitative and quantitative criteria (evaluation indicators) that can be classified business data and protected by each class.

• The Korean Journal of Malacology
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• v.3 no.1
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• pp.3-14
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• 1987

The electrophoretic and innunological cnalyses of organic matrices in the shells of freshwater bivalves were made in order to dlucidate the biochemical characteristics and species-specific differinces of the applied shells, The water-soluble and insoluble matrices of four species of freshwater bivalves, Andodonta fukudai, Unio douglasiae, Lanceolaria and Chrbicula fluminea, were used as analytical materials, There was non-identity in immuno affinity between anti soluble matrix(anti-Sm) and anti insoluble matrix(anti-ISM)sera against the organic matrix of Andodnta fukudai. The SMs of four species (S. fukudai, U.douglasiae, L. acrorhyncha, and C. fluminea) showed the differences in the precipitate arcs at the level of family, though ISMs did mot show differences. In the electrophoretic analysis, all foru species had two SDS-electrophoretic bands of SM, of which molecular wights appeared to be lower than 55,000, shereas the native organic matrices of foru speceis had higher molecular weighrs than those from SDS-dldctrophoresis. Only calcium ion among many ions in extrapallial fluid(EPF) caused SM to change into insoluble molecules, thus the EPF pretreated with Ca++did not form the precipitate arc when did the immuno diffusion whth anti SM serum. ISM precursor may be polymerized into macromolecules like periostracin, a precusor of periostracum, judging from the similat polymerization patterns in 0.1M Tris formate buffer(pH 3); they may be made insoluble macromolecules due to their strong natrue of hydrophobicity.

• Journal of Information Technology Applications and Management
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• v.26 no.4
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• pp.31-39
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• 2019

The 129 public institutions in Korea are subject to Information Security Management Condition Evaluation (ISMCE) as a part of the government management evaluation system by the Ministry of Economy and Finance. ISMCE is started in 2006 with the central government institutions, and applied to the all public institutions in 2009. This evaluation is annually conducted by the National Intelligence Service through the site visits, and the number of the evaluated institutions is increasing year by year. However, the process of ISMCE - identifying existing vulnerabilities in the information system - is conducted manually. To improve this inconvenience, this paper introduces the various evaluation system in the major countries, especially in the United States, and analyzes the Security Content Automation Protocol (SCAP) by NIST. SCAP is automation protocol for the system vulnerability management (in technical fields) and security policy compliance evaluation. Based on SCAP, this paper suggests an improvement plan for the ISMCE of Korea.