• Journal of Periodontal and Implant Science
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• 제53권5호
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• pp.347-361
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• 2023

Purpose: Exosomes are membrane vesicles that are present in body fluids and contain proteins, lipids, and microRNA (miRNA). Periodontal tissue examinations assess the degree of periodontal tissue destruction according to the probing depth (PD), clinical attachment loss (CAL), bleeding on probing, and X-ray examinations. However, the accurate evaluation of the prognosis of periodontitis is limited. In this study, we collected saliva from patients before and after initial periodontal therapy (IPT) and compared changes in the clinical parameters of periodontitis with changes in the components of salivary exosomes. Methods: Saliva was collected from patients with stage III and IV periodontitis at the first visit and post-IPT. Exosomes were purified from the saliva, and total protein and RNA were extracted. Changes in expression levels of C6, CD81, TSG101, HSP70, and 6 kinds of miRNA were analyzed by western blots and real-time polymerase chain reaction. Results: Patients with increased C6 expression after IPT had significantly higher levels of periodontal inflamed surface area (PISA), miR-142, and miR-144 before and after IPT than patients with decreased C6 expression after IPT. Patients with decreased and unchanged CD81 expression after IPT showed significantly higher PD, CAL, and PISA before IPT than after IPT. Patients with decreased and unchanged TSG101 expression after IPT had significantly higher PD before IPT than after IPT. Patients with increased HSP70 expression after IPT had significantly higher PD and PISA before and after IPT than patients with unchanged HSP70 after IPT. The expression levels of miR-142, miR-144, miR-200b, and miR-223 changed with changes in the levels of C6, CD81, TSG101, and HSP70 in the salivary exosomes of periodontitis patients before and after IPT. Conclusions: The expression levels of proteins and miRNAs in salivary exosomes significantly changed after IPT in periodontitis patients, suggesting that the components of exosomes could serve as biomarkers for periodontitis.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2011년도 제42회 하계학술대회
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• pp.1256-1257
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• 2011

유도급전용 변압기(Inductive Power Transformer, IPT)는 비접촉 전력전송장치이며, 그 응용범위는 전동칫솔용 충전기, 핸드폰용 충전기와 같은 소용량 시스템뿐만 아니라, 전기자동차, 산업용 이송장치, 철도 시스템과 같은 대용량 시스템에까지 확대되고 있다. 철도시스템과 같은 교통시스템에 적용되는 IPT 시스템의 경우, 소용량 시스템과 달리 큰 공극을 가지기 때문에 높은 에너지 전달 효율을 얻기 위하여 IPT 모듈의 주의 깊은 설계가 요구되기 때문에 본 논문에서는 철도차량에 적용하기 위한 U-U 타입 IPT와 U-I 타입 IPT의 등가회로 파라미터와 커플링 계수에 대한 특성을 해석적 방법을 통하여 분석하고, 실제 20[kW] 급 IPT 시제품 모듈의 실험을 통하여 등가회로 파라미터 검증 및 IPT 모듈의 효율 계측을 수행하였다.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2019년도 전력전자학술대회
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• pp.352-353
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• 2019

자기유도 무선전력 전송 (Inductive Power Transfer, IPT) 시스템에서 송 수신패드의 결합계수 k는 송신패드와 수신패드의 이격거리에 따라 가변된다. 송 수신패드의 결합계수에 따라 IPT 컨버터의 동작특성이 바뀌기 때문에, 일반적인 스위칭 주파수 제어 방법으로는 IPT 컨버터의 정상 동작 영역이 제한된다. 본 논문에서는 송 수신패드의 결합계수 계수에 따라 풀브릿지 구조의 IPT 컨버터 1차 측을 풀브릿지 또는 하프브릿지로 제어하여 동작 가능한 결합계수 범위를 확장할 수 있는 제어 방법을 제안하고, LCCL-S 구조의 IPT 컨버터에 적용하여 실험을 통하여 제어 방법의 타당성을 검증한다.

• Journal of Power Electronics
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• 제18권5호
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• pp.1434-1447
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• 2018

The control design of inductive power transfer (IPT) systems has attracted a lot of attention in the field of wireless power transmission. Due to the high-order resonant networks and multiple loads in IPT systems, a simplified model of an IPT system is preferred for analysis and control design, and a controller with strong robustness is required. Hence, an active disturbance rejection control (ADRC) for IPT systems is proposed in this paper. To realize the employment of ADRC, firstly a small-signal model of an LC series-compensative IPT system is derived based on generalized state-space averaging (GSSA), then the ADRC is implemented in the designed IPT system. The ADRC not only provides superior robustness to unknown internal and external disturbances, but also requires few knowledge of the IPT system. Due to the convenient realization of ADRC, the designed IPT system retains its simple structure without any additional circuits. Finally, a frequency domain analysis and experimental results have validated the effectiveness of the employed ADRC, especially its robustness in the presence of frequency drifts and other common disturbances.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 추계학술대회 논문집 전기기기 및 에너지변환시스템부문
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• pp.223-225
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• 2007

The contact-less inductive power transformer (IPT) uses principle of electromagnetic induction. Generally, there were many methods to improve the transfer performance of traditional transformer. But, though the principle of IPT is similar to that of general transformer, it is impossible to apply the methods because of large air-gap. Consequently, many linear numerical formulas for analysis of performance and design of traditional transformer cannot be used in development of IPT. The concept of the IPT for vehicle like PRT(Personal Rapid Transit) system is suggested and some suggestions for power collector(core & winding) design of IPT to improve power transfer performance arc presented in this paper. The characteristic of power delivery with these novel methods in design is presented by simulation and examination.

• 전기학회논문지
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• 제61권8호
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• pp.1210-1215
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• 2012

Traction motors for driving and power conversion devices using semiconductor switch are equipped with a transportation systems such as an electrical railway system. Power conversion devices have the possibility of malfunction by external electromagnetic waves. As a result, these could affect the safe operation of the railway. Moreover, the electromagnetic waves above safe limits will be harmful to the passengers inside the railway vehicles or anyone working around the rail-track. For this reason, the importance and need about the reliability check and complement of electromagnetic waves generated from the IPT(Inductive Power Transfer) system have been suggested for the safe application of the IPT system to the railway system. In this study, prediction for the electromagnetic wave properties was conducted through FEM(Finite Element Method) analysis of 5kW-class IPT system design model. Next, the 5kW IPT system prototype was made and then the small-scaled railway vehicle was made to mount the IPT system and the energy management system. Finally, the electromagnetic waves generated from the real small-scaled IPT system were measured and analyzed, and then the reliability check of predictions by FEM analysis were carried out.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2018년도 전력전자학술대회
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• pp.81-83
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• 2018

본 논문에서는 inductive power transfer (IPT) 시스템 2차측 semi-bridgeless 정류기에 pulse density modulation (PDM) 제어를 적용하기 위한 시스템 설계 방안을 제안한다. LCCL-S 토폴로지를 사용한 IPT 시스템에 PDM 제어를 적용하였을 때 나타나는 출력특성을 기존의 SS 토폴로지를 사용한 시스템의 출력특성과 비교 분석한다. 분석 결과를 바탕으로, 실제 전기자동차 배터리 충전사양을 고려하여 3.3 kW 급 IPT 시스템을 설계하고 설계 결과를 시뮬레이션을 통해 검증한다.

• 전력전자학회논문지
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• 제22권5호
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• pp.423-430
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• 2017

This paper proposes a control methodology for a high efficiency operation of an inductive power transfer (IPT) converter by combining full bridge (FB) and half bridge (HB) controls. To apply the proposed control to the IPT converter, the characteristics of each control method are analyzed. By examining the output voltages of the IPT converter and a theoretical loss analysis, the control shifting points between FB and HB controls are evaluated in accordance with the coupling coefficients and the load. Based on the control shifting points, the FB-HB control algorithm is implemented. By applying FB-HB control, high efficiency operation at the light load condition can be achieved.

• Journal of Preventive Medicine and Public Health
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• 제55권5호
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• pp.428-435
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• 2022

Objectives: The Indonesian Ministry of Health launched isoniazid preventive therapy (IPT) in 2016, with general practitioners (GPs) at the frontline of this program. However, the extent to which GPs have internalized this program remains uncertain. The aim of this study was to identify the knowledge and attitudes of GPs towards the IPT program in Indonesia. Methods: This study used an online, self-administered questionnaire distributed via e-mail and social messaging services. A logistic regression model was employed to identify the explanatory variables influencing the level of knowledge and attitudes toward IPT among GPs in Indonesia. An empirical analysis was conducted separately for each response variable (knowledge and attitudes). Results: Of the 418 respondents, 128 (30.6%) had a good knowledge of IPT. Working at a public hospital was the only variable associated with good knowledge, with an adjusted odds ratio (aOR) of 1.69 (95% confidence interval [CI], 1.02 to 2.81). Furthermore, 279 respondents (66.7%) had favorable attitudes toward IPT. In the adjusted logistic regression analysis, good knowledge (aOR, 0.55; 95% CI, 0.34 to 0.89), 1-5 years of work experience (aOR, 2.09; 95% CI, 1.21 to 3.60), and having experienced IPT training (aOR, 0.48; 95% CI, 0.25 to 0.93), were significantly associated with favorable attitudes. Conclusions: In general, GPs in Indonesia had favorable attitudes toward IPT. However, their knowledge of IPT was limited. GPs are an essential element of the IPT program in the country, and therefore, adequate information dissemination to improve their understanding is critical for the long-term viability and quality of the IPT program in Indonesia.

• Nuclear Medicine and Molecular Imaging
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• 제43권2호
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• pp.100-106
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• 2009

목적: 파킨슨병은 비교적 흔한 운동장애질환으로 흑질(substantia nigra)의 도파민성 신경세포와 해당되는 기저핵의 도파민 함유 신경말단의 퇴행성 변화에 의하여 선조체에서의 도파민 운반체 농도도 감소하는 것으로 알려져 있다. 본 연구는 I-123 IPT SPECT에서 선조체의 도파민 특이결합과 후두염 뇌피질의 비특이 결합비를 이용하여 초기 및 진행된 파킨슨병 환자군과 본태성 진전 등의 다른 운동장애 질환군, 정상 대조군에서 도파민 운반체 영상을 비교하였다. 대상 및 방법: 정상 대조군 50명과 초기 파킨슨병 환자군 20명, 진행된 파킨슨병 환자군 30명, 본태성 진전환자군 20명을 대상으로 I-123 IPT를 정맥 주사후 20분과 2시간 후에 SPECT 영상을 획득하고 재구성하였다. 후두염에 배후방사능 관심영역을 그리고 선조체의 I-123 IPT의 특이/비특이 결합비를 구하여 각 군간의 차이를 정량적 및 정성적으로 비교하여 보았다. 결과: 선조체의 I-123 IPT의 특이/비특이 결합비는 진행된 파킨슨병 환자군과 정상 대조군에서는 평균값의 차이가 유의하였다. 그러나 초기 파킨슨병 환자군과 본태성 진전 환자군 사이에는 특이/비특이 결합비가 중첩됨이 관찰되었다. 정상 대조군과 본태성 진전환자군에서는 2시간 영상이 20분 영상에 비하여 특이/비특이 결합비도 높게 나타났고 표준 편차도 적었다. 진행된 파킨슨병 환자에서는 20분 영상과 2 시간 영상의 특이/비특이 결합비는 차이가 없었고 그 값도 낮았다. 편측 파킨슨병 환자에서 I-123 IPT의 특이/비특이 결합비는 증상이 나타난 반대측 선조체뿐만 아니라 같은쪽 선조체에서도 감소되어 있었다. 초기 파킨슨 환자20명 중 편측 증상을 보인 7명의 환자에서 I-123 IPT SPECT상의 좌우측 선조체간의 특이/비특이 결합비 간의 차이를 이용한 편측화 결과는 임상 증상의 편측화와 일치하였다. 결론: I-123 IPT SPECT는 진행된 파킨슨병의 진단과 치료에 따른 임상경과 진행의 객관적인 지표로서의 역할을 할 수 있을 것으로 생각되며 임상 증상이 발현되기 전단계의 초기 파킨슨병의 진단이나 파킨슨병과 유사한 운동증상을 보일 수 있는 다른 운동질환군과의 감별진단에 있어서는 각 군간의 중첩되는 비율이 있으므로 적용에 신중을 기해야 하겠다.