• 제목/요약/키워드: IME

검색결과 90건 처리시간 0.021초

실시간 박테리아 감지를 위한 정전용량방식의 MEMS 바이오센서 (MEMS based capacitive biosensor for real time detection of bacterial growth)

  • 서혜경;임대호;임미화;김종백;신전수;김용준
    • 센서학회지
    • /
    • 제17권3호
    • /
    • pp.195-202
    • /
    • 2008
  • A biosensor based on the measurement of capacitance changes has been designed and fabricated for simple and realtime detection of bacteria. Compared to an impedance measurement technique, the capacitance measurement can make additional measurement circuits simpler, which improves a compatability for integration between the sensor and circuit. The fabricated sensor was characterized by detecting Escherichia coli(E. coli). The capacitance changes measured by the sensor were proportional to E. coli cell density, and the proposed sensor could detect $1{\times}10^6$ cfu/ml E. coli at least. The real-time detection was verified by measuring the capacitance every 20 minutes. After 7 hours of E. coli growth experiment, the capacitance of the sensor in the micro volume well with $4.5{\times}10^5$ cfu/ml of initial E. coli density increased by 20 pF, and that in another wells with $1.5{\times}10^6$ cfu/ml and $8.5{\times}10^7$ cfu/ml initial E. coli density increased by 56 pF and 71 pF, respectively. The proposed sensor has a possibility of the real-time detection for bacterial growth, and can detect E. coli cells with $1.8{\times}10^5$ cfu in nutrient broth in 5 hours.

Therapeutic alternatives in painful diabetic neuropathy: a meta-analysis of randomized controlled trials

  • Vilar, Samuel;Castillo, Jose Manuel;Martinez, Pedro V. Munuera;Reina, Maria;Pabon, Manuel
    • The Korean Journal of Pain
    • /
    • 제31권4호
    • /
    • pp.253-260
    • /
    • 2018
  • Background: One of the most frequent problems caused by diabetes is the so called painful diabetic neuropathy. This condition can be treated through numerous types of therapy. The purpose of this study was to analyze, as a meta-analysis, different treatments used to alleviate painful diabetic neuropathy, with the aim of generating results that help making decisions when applying such treatments to tackle this pathology. Methods: A search was conducted in the main databases for Health Sciences, such as PUBMED, Web of Science (WOS), and IME biomedicina (Spanish Medical Reports in Biomedicine), to gather randomized controlled trials about treatments used for painful diabetic neuropathy. The analyzed studies were required to meet the inclusion criteria selected, especially those results related to pain intensity. Results: Nine randomized controlled trials were chosen. The meta-analysis shows significant positive effects for those treatments based on tapentadol [g: -1.333, 95% CI (-1.594; -1.072), P < 0.05], duloxetine [g: -1.622, 95 % CI (-1.650; -1.594), P < 0.05], pregabalin [g: -0.607, 95% CI (-0.980; -0.325), P < 0.05], and clonidine [g: -0.242, 95 % CI (-0.543; -0.058), P < 0.05]. Conclusions: This meta-analysis indicates the effectiveness of the treatments based on duloxetine, gabapentin and pregabalin, as well as other drugs, such as tapentadol and topic clonidine, whose use is better prescribed in more specific situations. The results provided can help increase the knowledge about the treatment of painful diabetic neuropathy and also in the making of clinical practice guidelines for healthcare professionals.

메타분석을 통한 학교 체육에서의 심상훈련 효과 분석 (Analysis on the Effects of Image Training in School Physical Education Using Meta-Analysis)

  • 김의재;강현욱
    • 한국응용과학기술학회지
    • /
    • 제36권4호
    • /
    • pp.1041-1049
    • /
    • 2019
  • 이 연구는 학교 체육 현장에서 적용한 심상훈련의 효과가 어느 수준인지 살펴보고, 그 효과에 영향을 미치는 변인을 파악하는데 목적이 있다. 이와 같은 연구 목적을 달성하기 위해 1995년부터 2018년까지 학교 체육 현장에서 심상훈련의 효과성을 검증한 선행연구 10편을 메타분석 대상으로 선정하였다. 이 연구의 주요 결과를 제시하면 다음과 같다. 첫째, 학교 체육에서의 심상훈련 전체효과크기는 큰 효과 크기(Cohen, 1988)를 나타내었다. 둘째, 종속변인에 대한 효과크기는 운동기능에서 상대적으로 크게 나타났다. 셋째, 조절변인에 대한 효과크기 분석 결과, 운동 학습의 유형, 연령, 성별, 훈련 기간, 훈련 빈도, 훈련 시간은 심상훈련의 효과를 조절하는 주요 변인으로 나타났다. 이러한 연구결과를 토대로 학교 체육 현장에서 심상훈련을 효율적으로 적용하기 위한 시사점과 후속 연구의 방향성을 제안하였다.

이산화탄소 포집 시스템 개념설계 개발을 위한 시스템 엔지니어링 기반 접근방법 (Systems Engineering-based Approach In Developing Concept Design Of Carbon Capture System)

  • 이창환;홍대근;윤수철;서석환;서활원
    • 시스템엔지니어링학술지
    • /
    • 제9권2호
    • /
    • pp.23-36
    • /
    • 2013
  • Plant industry is one of technology-intensive and most prosperous industries in Korea because of its recent prosperity and promising outlook in export. However, no Korean EPC company has yet been well prepared in lifting their capacity sufficient enough to get the upstream conceptual or basic design and engineering orders for sizable plant projects which are known as the more value-added. If systems engineering, a methodology which developed complex systems such as airplanes and has been justified its effectiveness in Defense and NASA projects, can be integrated with plant engineering which should be developed and applied based on the requirements of so many stakeholders, conditions, lifecycle concepts, and constraints of the projects, huge synergic effect is expected particularly in developing a specific upstream design, which is a conceptual or basic design. The notion of integration with each other between systems engineering and plant engineering can be really the crux of EPC's success in any plant projects. This paper suggests an approach showing a methodology how to dig out, analyze, evaluate, verify and implement the stakeholders' requirements into a plant design in conceptual phase using the theory and skills of systems engineering. ISO/IEC 15288 well known systems engineering standards is used. Carbon capture system is used for a case study, for it is an emerging technology in reducing emissions of carbon dioxide causing global warming from flue gas after combustion. Here systems engineering was proven to play a substantial role in enhancing the capability of designers in developing a conceptual design of whole plant or certain part of crucial plant systems.

The Decarbonization of Sea Water by LD Slag

  • Han, Ki-Hyun;Kim, Hyung-Suek;M. S. Oh;Byeon, Tae-Bong
    • 대한전자공학회:학술대회논문집
    • /
    • 대한전자공학회 2001년도 The 6th International Symposium of East Asian Resources Recycling Technology
    • /
    • pp.532-536
    • /
    • 2001
  • LD slag, that is, a by-product of steel making process, has been mainly used as land construction materials. Recently, the seashore application of LD slag was tried in Japan and Korea but the reaction between LD slag and seawater was not studied yet. We tried to clarify the leaching reaction and/or mechanism of LD slag and the reaction between seawater and LD slag. We tried to apply these results to the decarbonization of seawater for seawater magnesia process. The high pH solution(over 12) was injected into the sea water and the pH of mixed liquid was adjusted to 9.8. This mixed solution was aged for 8 hours and the 104ppm of CO$_3$$^{-2}$ in the sea water was decreased to 23ppm with the negligible loss of $Mg^2$$^{+}$. The slag particle was directly inserted into the seawater fur practical application. The 0.5~1mm particles were suitable for decarbonization when 5 grade slags mentioned above were reacted with sea water. In this case, the content of CO$_3$$^{-2}$ in the sea water was 53 ppm with the negligible loss of $Mg^2$$^{+}$ after 8 hours aging. The direct application of slag particle fur the decarbonization of seawater takes more reaction time.ime.

  • PDF

한우 송아지의 이두이안체 (Derodidymus in Korean-Native Calf)

  • 강문일;박영석;한동운
    • 한국가축번식학회지
    • /
    • 제23권1호
    • /
    • pp.69-73
    • /
    • 1999
  • 머리와 목이 두 개인 이두이경체인 한우 송아지를 해부학적으로 관찰하였다. 이 한우 기형 송아지의 외형적 특정은 2 개의 완전한 머리와 목이 형성되어 있었으며 두 개의 경부는 흉강에서 유합되어 한 개의 몸통을 이루고 있었다. 두 개의 두부는 우측의 두부가 좌측의 두부에 비해 크기가 작고 상악과 하악의 비틀림이 심하게 나타나는 편측성 하악골 형성부전을 보였다. 두 개의 경부는 비슷한 길이로 흉부에서 유합되어 있었으며 2 개의 두부와 경부 외에 흉근 내부에 유착되어져 있는 흉골이 1 쌍으로 존재하고 있었다. 전지골격은 외부에 노출된 1 쌍의 완전한 골격과 매몰되어 있는 비교적 완전한 l 쌍의 전지골격외에 견갑부가 소실되고 상완골이 불완전한 l 쌍의 불완전한 전지 골격구조가 흉근과 늑골 사이에서 발견되었다. 그러나 기형적 전지와는 달리 후지는 정상적인 1 쌍의 다리만 보이었다. 경추의 부분적인 유합과 흉추 전반부가 심한 유합으로 척추가 뒤틀려져 있었다. 두개골은 정상적으로 2개의 눈과 귀, 비공과 1개의 업을 가지고 있었으며, 좌측이 우측 두부에 비해 크기가 작았고 하악도 더 심히 뒤틀려져 있었다. 뇌실은 위축되어 대뇌가 작았다. 기관과 식도는 흉강에서 유합되어 1개의 폐와 위로 이어지고 있었다. 흉강내 장기와 복강내 장기는 대부분 정상적인 구조를 유지하고 있었으나 대장의 직장 부분은 항문으로부터 5cm 떨어진 부분에 협착되어 있었으며 항문은 보이지 않았다.

  • PDF

이식형 인공중이 시스템을 위한 고효율 차동 전자 트랜스듀서의 설계 (Design of High Efficiency Differential Electromagnetic Type Transducer for Implantable Middle Ear System)

  • 송병섭;노철균;김명남;조진호
    • 센서학회지
    • /
    • 제11권3호
    • /
    • pp.171-182
    • /
    • 2002
  • 이식형 인공중이에 사용되는 일반적인 전자기 방식의 진동 트랜스듀서에 비하여 두 개의 소형 영구자석을 같은 극끼리 접착한 후 코일내부에 위치시킨 차동 전자 트랜스듀서는 효율이 높고 코일-영구자석간의 공극조정이 필요 없으며 외부의 자기장에 대하여 영향을 받지 않는 특성을 가진다. 본 논문에서는 이러한 차동 전자 트랜스듀서를 이식형 인공중이 시스템에 사용하기 위하여 입력전류에 대하여 진동력의 크기를 최대화시킬 수 있는 효율적인 구조를 제안, 해석하였다. 유한요소 해석을 통하여 가장 효율적인 코일과 자석의 길이 비를 도출하였고 소리신호 전달을 위한 트랜스듀서의 필요 진동력을 산출한 후 트랜스듀서 발생 진동력을 해석하였다. 그리고 실제 이소골에 이식할 수 있는 크기의 트랜스듀서를 제작하기 위한 설계상수를 추출하였다. 계산된 설계상수를 이용하여 이식 가능한 크기로 트랜스듀서를 구현한 후 무부하 실험과 사체 부하 실험을 실시하여 제작된 트랜스듀서가 실제 중등이상 고도난청자를 위한 이식형 인공중이 시스템에 사용될 수 있음을 증명하였다.

신기술 제품의 ASL 추정-솔라셀 사례 중심으로 (A Study on the Estimation of Average Service Life for New Technology Products-in Case of Solor-cell)

  • 조진형;이세재;오현승;백성선;김옥재;김병극;정경수;박상훈;권대철;고재호;유지현;심성철
    • 산업경영시스템학회지
    • /
    • 제37권4호
    • /
    • pp.106-115
    • /
    • 2014
  • Until now, because a new product (or facility) launched in market has been retired from one year of age, we can have had ASL by stub-curve method by Iowa curve. Recently, many innovative products with important role in market like display and solar-cell etc. are more durable and, what are better, they have the constant variance in ASL because of their good quality. Of course, there are some ones like smart mobile phone with relatively big dispersion in ASL. Estimating ASL of products like display and solar-cell etc., the new approach is needed. In this paper a new method applied traditional Iowa curve with accelerated reliability test (indoor/outdoor) etc. is proposed.

제한적 시장을 가지는 천연자원의 가격예측 모형에 관한 연구 (A Model on Price Forecasting of Natural Resources with Restricted Market)

  • 심성철;이세재;오현승;김병극;김옥재;신동원;신승남;조명호;정연학;송인철;조진형
    • 산업경영시스템학회지
    • /
    • 제37권4호
    • /
    • pp.82-89
    • /
    • 2014
  • Recently, the mineral resource protection policies and regulations in production countries of natural resources including rare metals are becoming more stringent. Such environment makes which market has malfunction. In other word, those are not perfect or pure market. Therefore because each market of natural resources have special or unique characters, it is difficult to forecast their market prices. In this study, we constructed several models to estimate prices of natural resources using statistical tools like ARIMA and their business indices. And for examples, Indium and Coal were introduced.

휴대폰 애프터서비스 품질이 고객만족과 고객충성도에 미치는 영향 (The Influence of After-Sales Service Quality on Customer Satisfaction and Loyalty in Mobile Phone)

  • 이재준;유지현;이세재;오현승;조진형
    • 산업경영시스템학회지
    • /
    • 제40권4호
    • /
    • pp.87-95
    • /
    • 2017
  • This study aims to configure what dimensions make up for smart phone after service quality, and how this service quality affects customer satisfaction and customer loyalty. Smart phone market is a market of the device leading the digital convergence as well as positioning itself as one of the national growth driving industry. To survive in this matured market, companies should have to respond actively to radical changes and customers needs in the so-called Smart Revolution environment. Lately, however, the smart phone market is prospected to move from growth phase to mature phase by the scholars. In order to proactively respond to the change in such market condition, companies need to provide absolute advantage in customer loyalty over their competitors by revolutionizing the after-sales service quality. Qualified A/S will lead to service satisfaction and achieve customer loyalty. The empirical analysis results obtained through A/S quality are as follows : First, human quality (attitude, expertise, problem-solvability), environment quality (handling agility, convenience, comfort), service policy quality (quality guarantee, additional service operation) are dimensions that make up for A/S quality. Second, A/S quality dimension showed a significant positive influence on service satisfaction and A/S satisfaction showed a positive influence on customer loyalty as well. Based on this empirical study, we propose some implications for A/S quality improvement. First, human quality dimension has relatively higher influence on A/S satisfaction in case of free A/S, so companies need to solve the product problem completely when consumer's first visit by continual employee education. Second, in case of paid A/S, the service policy quality-especially A/S Warranty period- has higher influence on A/S satisfaction.