• 제목/요약/키워드: IL-12A

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Evaluation of Reference Intervals of Some Selected Chemistry Parameters using Bootstrap Technique in Dogs (Bootstrap 기법을 이용한 개의 혈청검사 일부 항목의 참고범위 평가)

  • Kim, Eu-Tteum;Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.24 no.4
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    • pp.509-513
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    • 2007
  • Parametric and nonparametric coupled with bootstrap simulation technique were used to reevaluate previously defined reference intervals of serum chemistry parameters. A population-based study was performed in 100 clinically healthy dogs that were retrieved from the medical records of Kangwon National University Animal Hospital during 2005-2006. Data were from 52 males and 48 females(1 to 8 years old, 2.2-5.8 kg of body weight). Chemistry parameters examined were blood urea nitrogen(BUN)(mg/dl), cholesterol(mg/dl), calcium(mg/dl), aspartate aminotransferase(AST)(U/L), alanine aminotransferase(ALT)(U/L), alkaline phosphatase(ALP)(U/L), and total protein(g/dl), and were measured by Ektachem DT 60 analyzer(Johnson & Johnson). All but calcium were highly skewed distributions. Outliers were commonly identified particularly in enzyme parameters, ranging 5-9% of the samples and the remaining were only 1-2%. Regardless of distribution type of each analyte, nonparametric methods showed better estimates for use in clinical chemistry compare to parametric methods. The mean and reference intervals estimated by nonparametric bootstrap methods of BUN, cholesterol, calcium, AST, ALT, ALP, and total protein were 14.7(7.0-24.2), 227.3(120.7-480.8), 10.9(8.1-12.5), 25.4(11.8-66.6), 25.5(11.7-68.9), 87.7(31.1-240.8), and 6.8(5.6-8.2), respectively. This study indicates that bootstrap methods could be a useful statistical method to establish population-based reference intervals of serum chemistry parameters, as it is often the case that many laboratory values do not confirm to a normal distribution. In addition, the results emphasize on the confidence intervals of the analytical parameters showing distribution-related variations.

Growth Characteristics and Forage Productivity of New Forage Barley Variety, 'Miho' (청보리 신품종 '미호'의 생육특성과 수량성)

  • Oh, Young-Jin;Park, Tae-Il;Park, Hyoung-Ho;Han, Ouk-Kyu;Song, Tae-Hwa;Park, Jong-Chul;Kim, Yang-Kil;Park, Jong-Ho;Kang, Hyeon-Jung;Kang, Chon-Sik;Cheong, Young-Keun;Kim, Kyong-Ho;Kim, Bo-Kyeong;Yun, Geon-Sig;Hong, Gi-Heung;Bae, Jeong-Suk;Lee, Seong-Tae
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.4
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    • pp.370-375
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    • 2016
  • The purpose of development new variety 'Miho' (Hordeum vulgare L.) is a favorite with livestock feed and develop varieties resistant to disease and lodging. 'Miho' was carrying out the growth habit of group III with green and mid-wide leaf. Awn that is related to preference of livestock is a semi-smooth awn. This cultivar had 96 cm of culm length, 650 of spikes $per\;m^2$. Heading date of 'Miho' was April 27, and maturing date on May 30, which were later than cultivar 'Youngyang'. It also showed strong winter hardiness, and similar resistance to shattering and bariy yellow mosaic virus (BaYMV) compared with those of check one. The best thing among the traits of a good quality with the plant green at the latter growing period. The average forage dry matter yield in the regional yield trial was about 13.1, 12.1 MT per ha in upland and paddy field, respectively, which were 9%, 2% higher than that of the check cultivar. It's also showed 6.8% crude protein, 27.1% ADF (acid detergent fiber), and 67.5% TDN (total digestible nutrients), including higher silage quality for whole crop barley. This cultivar would be suitable for the area whose average minimum temperature was above $-8^{\circ}C$ January in Korean peninsula.

QTL Analysis of Concerned on Ideal Plant Form in Rice (벼의 이상적인 초형에 관여하는 QTL 분석)

  • Chung, Il Kyung;Kim, Kyung-Min
    • Korean Journal of Plant Resources
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    • v.30 no.2
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    • pp.213-218
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    • 2017
  • Rice is the staple food of at least half of the world's population. Due to global warming, the weather is difficult to forecast nowadays. Therefore, it is necessary to breed various breeding to respond to such changes in the environment. This study was conducted to analyze the QTL about plant form, culm length, ear number and ear length by using 120 lines by anther culture, a cross between the Indica variety Cheongcheong and Japonica variety Nagdong. DNA marker was selected on the QTLs gene, and the following results were obtained. CNDH (Cheongcheong Nagdong Doubled Haploid) lines frequency distribution table curves about culm length, ear number and ear length exhibited showed a continuous variation close to a normal distribution. QTL analysis result, on culm length qPlL1-1 and qPlL1-2 were detected on the chromosome 1 and qPlL5 was detected on the chromosome 5. However, on ear length qPL2, qPL3 and qPL10, were detected on the chromosome 2, 3 and 10, while on ear number qPN1-1 and qPN1-2 were detected on the chromosome 1, qPN9 was detected on the chromosome 9. The QTLs related to culm length was found to chromosomes 5 and LOD scores were 3.81. The QTLs related to ear length was found to chromosomes 2 and 3 LOD scores were 7.13 and 3.20. The QTLs related to ear number was found to chromosome 9 and LOD scores were 4.27. Twenty two (22) Japonica cultivars and 12 Indica cultivars were analyzed polymorphisms, using selected 9 markers from the result about plant form analysis. RM5311, RM555 and RM8111 about the culm length, the ear length and number of ear were selected on the standard of Cheongcheong and Nagdong. Each rate of concordances about the culm length, the ear length and number of ear are 44.11%, 41.17% and 44.11%.

Chemical Composition Characteristics of Dustfall in Nakdong River Area (낙동강 하류역 강하먼지의 화학적 조성 특성)

  • Jeon, Byung-Il;Hwang, Yong-Sik
    • Journal of the Korean earth science society
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    • v.25 no.6
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    • pp.428-442
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    • 2004
  • Dustfall samples were collected by the modified American dust jar (bulk type) at 5 sampling sites in the Nakdong river area from lune 2002 to May 2003. Nineteen chemical species (Al, Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, Si, V, Zn, $Cl^-$, $NO_3^-$, $SO_4^{2-}$, and $NH_4^+$) were analyzed via the combination of ICP/AES, AAS, IC and UV. The purposes of this study were to qualitatively evaluate the chemical composition of dustfalls by examining their regional and seasonal distribution patterns. Computation of the enrichment factor showed that well-defined anthropogenic sources, particularly in Pb were found in the order Gamjeondong (industrial area), Wondong, Silla University, Samrangiin and Mulgum. The seasonal mean of soil contribution showed its highest value (16.3%) during the winter with an annual mean of 11.2%. The concentration ratio of [$SO_4^{2-}/NO_3^-$] was found to be highest (5.12) during the winter, while the lowest ratio value (3.30) was seen during the all. fall, Also regional equivalent ratios of [$SO_4^{2-}/NO_3^-$] were found in the order: Silla University (6.78), Gamjeondong (4.98), Mulgum (3.95), Wondong (3.85), and Samrangjin (2.87). Seasonal distribution of water soluble components for total dustfall were found in the order: spring (71.6%), summer (61.2%), fall (49.2%) and winter (48.6%) with a mean ratio of 57.6%. Regional contribution of sea salts of water soluble ions were found in the order: Silla university (34.5%), Gamjeondong (28.3%), Wondong (17.3%), Samrangiin (17.2%) and Mulgum (13.8%), the total mean contribution rate was 22.1%. As for the chemical composition of dustftll on the lower Nakdong river, there is a decreased influence of sea salt and artificial anthropogenic sources and increased influence of soil particle inland. Also, the total amount of deposition on the lower Nakdong river has decreased, with the river's surface serving as a confounding factor in resuspending dusts.

Development and Performance Evaluation of an Animal SPECT System Using Philips ARGUS Gamma Camera and Pinhole Collimator (Philips ARGUS 감마카메라와 바늘구멍조준기를 이용한 소동물 SPECT 시스템의 개발 및 성능 평가)

  • Kim, Joong-Hyun;Lee, Jae-Sung;Kim, Jin-Su;Lee, Byeong-Il;Kim, Soo-Mee;Choung, In-Soon;Kim, Yu-Kyeong;Lee, Won-Woo;Kim, Sang-Eun;Chung, June-Key;Lee, Myung-Chul;Lee, Dong-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.6
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    • pp.445-455
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    • 2005
  • Purpose: We developed an animal SPECT system using clinical Philips ARGUS scintillation camera and pinhole collimator with specially manufactured small apertures. In this study, we evaluated the physical characteristics of this system and biological feasibility for animal experiments. Materials and Methods: Rotating station for small animals using a step motor and operating software were developed. Pinhole inserts with small apertures (diameter of 0.5, 1.0, and 2.0 mm) were manufactured and physical parameters including planar spatial resolution and sensitivity and reconstructed resolution were measured for some apertures. In order to measure the size of the usable field of view according to the distance from the focal point, manufactured multiple line sources separated with the same distance were scanned and numbers of lines within the field of view were counted. Using a Tc-99m line source with 0.5 mm diameter and 12 mm length placed in the exact center of field of view, planar spatial resolution according to the distance was measured. Calibration factor to obtain FWHM values in 'mm' unit was calculated from the planar image of two separated line sources. Te-99m point source with i mm diameter was used for the measurement of system sensitivity. In addition, SPECT data of micro phantom with cold and hot line inserts and rat brain after intravenous injection of [I-123]FP-CIT were acquired and reconstructed using filtered back protection reconstruction algorithm for pinhole collimator. Results: Size of usable field of view was proportional to the distance from the focal point and their relationship could be fitted into a linear equation (y=1.4x+0.5, x: distance). System sensitivity and planar spatial resolution at 3 cm measured using 1.0 mm aperture was 71 cps/MBq and 1.24 mm, respectively. In the SPECT image of rat brain with [I-123]FP-CIT acquired using 1.0 mm aperture, the distribution of dopamine transporter in the striatum was well identified in each hemisphere. Conclusion: We verified that this new animal SPECT system with the Phlilps ARGUS scanner and small apertures had sufficient performance for small animal imaging.

Breeding of the Scab-Resistant Pear Cultivar 'Greensis' (배 검은별무늬병 저항성 품종 '그린시스' 육성)

  • Kim, Yoon-Kyeong;Kang, Sam-Seok;Won, Kyung-Ho;Shin, Il-Sheob;Cho, Kwang-Sik;Ma, Kyeong-Bok;Kim, Myung-Su;Choi, Jang-Jeon;Choi, Jin-Ho
    • Horticultural Science & Technology
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    • v.34 no.4
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    • pp.655-661
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    • 2016
  • To develop scab-resistant pear (Pyrus spp.) varieties with fruits that are as crisp and juicy as Asian pears, a cross was made between 'Whangkeumbae' and 'Bartlett' varieties (P. pyrifolia ${\times}$ P. communis) at the Pear Research Institute of the National Institute of Horticultural & Herbal Science, Rural Development Administration, in 1994. Among the 285 seedlings, 'Greensis' was first selected in 2006 for its good eating quality and named in 2012 after regional adaptation tests in nine regions and ten experimental plots from 2007 to 2012. The tree showed a vigorous growth habit and semi-spreading characteristics, like 'Whangkeumbae'. The optimum fruit harvest date was also around Sept. 26 and fruit was round in shape and green in skin color at maturity. Average fruit weight was 470g, and the soluble solids content was $12.4^{\circ}Brix$. The flesh was very crisp and juicy, and had good eating quality. Its' leaf size was similar with 'Bartlett' and smaller than 'Whangkeumbae'. The average of full bloom date of 'Greensis' was determined as Apr. 26, which was six days later than 'Whangkeumbae' and similar with 'Bartlett'. S genotypes of 'Greensis' were identified as $S_4S_e$ by S-allele PCR product sequencing analysis. It seems that the $S_4$ allele was inherited from 'Whangkeumbae' and the Se allele from 'Bartlett'. 'Greensis' displayed strong resistance to scab disease caused by Venturia nashicola, similar to European pear cultivars like 'Beurre Hardy' and, 'Conference'. 'Greensis' was also highly resistant to black leaf spot (Alternaria kikuchiana) in the field

EVA Sheet and Butyl Rubber based Waterproofing·Anti-Corrosion Sheet for Corrosion Maintenance and Repairing in the Interior Side of the Large Steel Pipes in Water Treatment Facilities (상수도용 대구경 녹 발생 강관 내부의 보수 및 성능 유지를 위한 EVA 시트와 부틸고무를 합지한 자착식 방수방식 시트의 부착성능 평가)

  • An, Ki-Won;Kim, Byoung-Il;Oh, Sang-Keun
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.5 no.3
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    • pp.267-274
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    • 2017
  • This study discusses the applicability of environmental friendly EVA based butyl rubber self-adhesive waterproof sheet designed to prevent corrosion of large scale pipes used in the water treatment facilities during th water treatment process. The experiments conducted tested the waterproofing sheet's adhesion strength on the steel surface of the pipes and checked for whether the material has the proper response properties against the various environmental conditions. In addition, it the sheet adhered to the steel pipe was to see if the adhesion hold against the water pressure due to the ingress of inflow water. Finally, the waterproofing sheet's adhesion strength was tested on a rusted steel surface to confirm whether the material has the necessary properties to secure stable adhesion strength and prevent corrosion of steel pipes at the same time during the process of installation or maintenance. As a result, the self-adhesive waterproof sheets showed that all attachments in the untreated, long term pressuring, immersion in chemical substance (hydrochloric acid, hypochlorous acid, sodium hydroxide), low temperature ($-20^{\circ}C$) conditions showed a adhesion performance of higher than 1.5N/mm, which is the performance standard of KS F 4934. Also, in the testing to check for the adhesion property against inverse water pressure, it was observed that the adhesion failure did not occur even up to $3.0N/mm^2$ pressure. Also, in the process of assessing the adhesion performance on rusted steel surface, specimens after 12 hours of corrosion treatment was shown to have 2.1N/mm, and specimens after 168 hours of corrosion treatment was shown to have 2.0N/mm adhesion strength performance.

The State and Problem of the Soft Contact Lens Wearer (소프트 콘택트렌즈 착용자의 실태와 문제점)

  • Kim, Douk-Hoon;Hwang, Sun-Young
    • Journal of Korean Ophthalmic Optics Society
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    • v.3 no.1
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    • pp.249-258
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    • 1998
  • This study was researched the state and problem of the soft contact Lens wear by the history and inverted microscopy. The results was as follows; 1. The first use of contact lens wear was the 15 years and the last use was the 26 years. The first age of most contact lens wear was the 19 years. 2. In the almost contact lens wearers, the first visual test was the optical shop. 3. At present, almost soft contact lens purchase the optical shop 4. At present, most contact lens wearer like a soft type. 5. At present, most soft contact lens were a domestic production, and some subjects were foreign country production, but some subjects were unknown. 6. After contact lens wear, most subjects don't known the corrected visual acuity, especially, almost people don't known the binocular visual acuity. 7. At present, on soft contact lens color, the teens like the non-color contact lens, twenties like the color contact lens, but thirties was not known. 8. On the advantage of soft contact lens knowledge, most teens and twenties were only one, thirties was unknown. 9. On the disadvantage of soft contact lens knowledge, most teens and thirties were only one, twenties were two. 10. On the side effect of soft contact lens wearer, teens was one, and twenties and thirties don't known. 11. On the main symptoms of soft contact lens wearer, total kinds were seven, On these kinds, most subjects were not symptoms, the next order was unknown on the symptom. But, On the symptoms, the main symptoms was the pain and dry eye. 12. At present, the research on the surface morphology of soft contact lens by inverted microscope, the lens repture, lens folding, foreign body immersion and etc were present. Above the study, most contact lens was soft lens, and the purchase was the optical shop, on the other hand, the knowledge of soft contact lens and visual acuity was few. As a results, On the practical problems of soft contact lens wear, the optician have to the soft contact lens treatment and aftercare by law and educational supporting.

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Control of Microorganisms in School Refectories and Kitchens Using Ozone Water and Ozone Gas (오존수 및 오존가스를 이용한 학교급식에서의 미생물 제어)

  • Choi, Jin-Kyung;Shin, Il-Shik;Kim, Dae Uk;Kim, Hee-Yun
    • Korean Journal of Food Science and Technology
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    • v.47 no.5
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    • pp.586-592
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    • 2015
  • This study was performed to determine optimum approaches for control of microorganisms in school refectories and kitchens. A reduction of more than 5.0 log CFU/mL was noted for Escherichia coli O157:H7, Salmonella Typhimurium, Listeria monocytogenes, Staphylococcus aureus, and Streptococcus mutans after treatment with 5 ppm ozone water for 60 s. Treatment of different vegetables with ozone water for 5 min showed bactericidal effects with 2-4 log reduction of viable cell number; the bactericidal effects differed according to the kinds of vegetables. The viable cell number on kitchen apparatus and tableware was not detected by ozone water treatment for 60 s. In addition, the count of the bacteria floating in the air in refectories and kitchens decreased 2.0 log CFU/1,000 L air to 0-1 CFU/1,000 L air on treatment with 45 ppm ozone gas for 12 hr. Therefore, ozone water and ozone gas may be good candidates as antimicrobial agents that can be used to improve sanitary conditions in school refectories and kitchens.

Dietary Effect of Agaricus bisporus Feeds on Characteristics of Eggs (계란의 품질특성에 미치는 양송이 사료의 식이효과)

  • Shin, Kyung-Ok;Kim, Dae-Gon;Lee, Sang-Il;Oh, Seung-Hee;Kim, Soon-Dong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.9
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    • pp.1195-1201
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    • 2009
  • Dietary effects of Agaricus bisporus powder (ABP) on the quality characteristic of eggs from hens (Hy-Line) were investigated. Experimental groups (100 hens/group) were divided into normal control group (Control), 0.3% ABP supplemented diet group (M-0.3) and 0.6% ABP supplemented diet group (M-0.6), then fed for 12 weeks. There were no significant differences in shell thickness, while Haugh unit in M-0.3 and M-0.6 groups were 18.3$\sim$27.6% higher than that of control groups. Color $L^*$ and $b^*$ values of egg albumen and yolk in the M-03 and M-0.6 groups were lower whereas $a^*$ values were higher than those of NC group. In the yolk of M-03 and M-0.6 groups compared with control groups, the levels of total phospholipids and HDL-cholesterol were 4.5$\sim$13.9% and 86.1$\sim$87.0% higher, respectively, while the levels of total cholesterol, triglyceride and LDL-cholesterol were 29.4$\sim$31.9%, 51.9$\sim$52.4% and 49.1$\sim$53.5% lower than those of control groups, respectively. There were no significant differences in fatty acids. In the result of sensory evaluation, gory odor of raw eggs in the M-03 and M-0.6 groups was slightly lower compared with control groups. These results suggest that the feed containing mushroom of Agaricus bisporus can be used to reduce the egg yolk cholesterol content and gory odor from raw egg, and also to increase the phospholipids as a functional feed. Further studies on the mechanism are required.