• Journal of the Korean Applied Science and Technology
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• v.37 no.3
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• pp.571-581
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• 2020

The purpose of this study was to investigate the effect of endurance and resistance exercise by using different intensity on diabetic-related blood profiles in impaired glucose tolerance mice. 54 C57BL/6 mice were divided into (1) Control group (CO, n=9), (2) impaired glucose tolerance group (IGT, n=9), (3) IGT + 50% of VO_2max endurance exercise group (IGT50A, n=9), (4) IGT + 75% of VO_2max endurance exercise group (IGT75A, n=9), (5) IGT +50% of 1RM resistance exercise group (IGT50R, n=9), 그리고 (6) IGT + 75% of 1RM resistance exercise group (IGT75R, n=9). Endurance exercise program was performed 40 min/day, 5 days a week for 8 weeks on treadmill. Resistance exercise program was consisted in ladder-climbing 8 set/day, 5 days a week for 8 weeks. After completed the exercise program, there was no different insulin level in the groups. The fasting glucose was significantly lower in CO than in other groups, and it was not different among the exercised groups. However, IGT75R was statistically lower than IGT. HOMA-IR was only different between CO and IGT. HbA1c was higher in IGT than in other groups. As compared with exercised groups, IGT 75A was lower than IGT50R. TC was lower in CO than in other groups, but there was no different in TG. Endurance exercise groups showed higher than CO and IGT in HDL-C level. LDL-C was lower in CO than other groups. In addition, IGT75A was lower than IGT and IGT50R in LDL-C level. In conclusion, 75% of 1RM resistance exercise had more positive effect on fasting glucose, and 75% of VO_2max endurance exercise improved HbA1c and LDL-C level. In addition, endurance exercise had more effective in HDL-C improvement as compared with resistance exercise.

• Journal of the Korean Applied Science and Technology
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• v.36 no.3
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• pp.804-812
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• 2019

The purpose of this study was to investigate the effects of different types of exercise training on neurodegeneration and cognitive function in mice with impaired glucose tolerance (IGT). Thirty-six male C57BL/6 mice were randomly assigned to the control (CO, n = 9) and impaired glucose tolerance (IGT, n = 27) groups. The IGT group consumed 45% high fat diet for 4 weeks and received 40 mg/kg of streptozotocin twice in the lower abdomen to induce IGT. After the IGT induction period, the IGT group was subdivided into IGT + sedentary (IGT, n = 9), IGT + endurance exercise (IGTE, n = 9), and IGT + resistance exercise (IGTR, n = 9). The IGTE and IGTR groups performed treadmill and ladder climbing exercises 5 times per week for 8 weeks, respectively. Fasting glucose and glycated hemoglobin (HbA1c) levels were significantly higher in IGT group than in CO, IGTE, and IGTR groups (p < 0.05). HOMA-IR was significantly higher in IGT group than CO group (p < 0.05). Hippocampal catalase (CAT) was significantly lower in IGT group than in CO group (p < 0.05), while beta-amyloid ($A{\beta}$) was significantly higher in IGT group than in CO group (p < 0.05). Hippocampal tau was significantly higher in IGT group than in CO, IGTE, and IGTR groups (p < 0.05). The Y-maze test performance for cognitive function was significantly lower in IGT group than in CO, IGTE, and IGTR groups (p <0.05). These results suggest that IGT induces neurodegeneration and negatively affects cognitive function, while regular exercise may be effective in alleviating neurodegeneration and cognitive decline regardless of exercise type.

• Physical Therapy Rehabilitation Science
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• v.5 no.2
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• pp.63-69
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• 2016

Objective: To evaluate the effects of sit-to-stand (STS) imagery group training (IGT) on STS movement and balance performance for chronic hemiparetic stroke. Design: Randomized controlled trial. Methods: A total of 30 people with chronic hemiparetic stroke (15 for STS-IGT group and 15 for control) were recruited in this study. The STS-IGT group participated in a videotape-based STS-IGT for 30 minutes a day, five days a week for six weeks, while the control group watched a documentary on television for the same period. The STS-IGT focused on a five-stage protocol. Specifically, external imagery was used during the four phases of the STS movement from the seat of the chair to standing up. All of the participants also participated in a regular rehabilitation program. STS movement and balance performance were assessed using three clinical measures. Results: After training, time to perform the 5-repetition STS test significantly increased in the STS-IGT group (change value, $4.0{\pm}2.0$ sec) compared with the control group (change value, $0.9{\pm}0.7$ sec) (p<0.05). There was a greater improvement in Berg balance scale scores in the STS-IGT group (change value, $0.2{\pm}4.1$ points) compared with the control group (change value, $0.3{\pm}0.9$ points) (p<0.05). There was a greater improvement in Timed Up and Go scores in the STS-IGT group (change value, $2.6{\pm}1.5$ sec) compared with the control group (change value, $0.9{\pm}1.0$ sec) (p<0.05). Conclusions: STS-IGT can be considered as a useful option for restoration of STS movement and balance performance for individuals with chronic hemiparetic stroke who are unable to fully participate in physical activities.

• Journal of Korean Society of Forest Science
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• v.99 no.1
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• pp.47-51
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• 2010

The purpose of this study was to analyze the effect of acute forest walking exercise on blood glucose of IGT (impaired glucose tolerance), NIDDM (non-insulin dependent diabetes mellitus) in the elderly. There were four groups (n=60): forest walking exercise with IGT group (n=15; $66.21{\pm}4.16$ yrs), forest walking exercise with NIDDM group (n=15; $64.85{\pm}3.23$ yrs), field walking exercise with IGT group (n=15; $67.44{\pm}1.78$ yrs), field walking exercise with NIDDM group (n=15; $65.55{\pm}8.21$ yrs). They were tested on blood glucose levels at the beginning and at the end of each walking exercise. While the forest walking groups (interval + resistance exercise) worked for 40minutes with HRmax 50~60% level, the field walking groups (only aerobic exercise) worked for 40 minutes with HRmax 50~60% level. For data analysis, mean and standard deviation scores were calculated, and paired t-test and ANCOVA test were used. This study resulted in as follows. First, both walking groups showed the significant decrease of blood glucose in impaired glucose tolerance (IGT) after completing each exercise. Second, while the forest walking group showed the significant decrease of blood glucose in insulin dependent diabetes mellitus (NIDDM) after completing the forest exercise, the field walking group did not present any decrease of blood glucose in NIDDM after the field walking exercise. Therefore, the present findings suggest that the forest walking exercise as an interval and resistance exercise may be more effective to decrease blood glucose for IGT and NIDDM peoples in comparison to the field walking exercise as an aerobic exercise.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3389-3393
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• 2015

Background: Chronic inflammation could affect the occurrence and development of malignant tumors. To explore the levels of tumor necrosis factor ${\alpha}$ (TNF-${\alpha}$) and C-reactive protein (CRP) in patients accompanied by impaired glucose tolerance (IGT) and their clinical significance. Materials and Methods: A total of 210 patients hospitalized in Affiliated Hospital of Taishan Medical University from Jun., 2013 to Dec., 2014 were selected, in which 92 cases were accompanied by IGT. Meanwhile, 80 randomly-selected healthy people by physical examination were as the control. The levels of routine biochemical indexes, plasma TNF-${\alpha}$ and CRP in all subjects were measured. Results: Both systolic and diastolic pressures in hypertension group and hypertension plus IGT group were significantly higher than in control group (p<0.01), but there was no statistical significance between these two groups (p>0.05). The levels of fasting plasma glucose (FPG) and blood glucose 2 h after taking glucose in hypertension plus IGT group were markedly higher than other groups (p<0.01). Homeostasis model assessment-insulin resistance (HOMA-IR), TNF-${\alpha}$ and CRP contents were on the progressive increase in control, hypertension and hypertension plus IGT groups, but significant differences were presented among each group (P<0.01). Hypertension accompanied by IGT had a significantly-positive association with CRP, TNF-${\alpha}$, FPG and blood glucose 2h after taking glucose. Conclusions: The levels of plasma TNF-${\alpha}$ and CPR in patients with hypertension accompanied by IGT increase significantly, indicating that inflammatory reaction in these patient increases, thus suggesting that these patients should be focused regarding cancer prevention.

• Journal of Korean Medical classics
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• v.24 no.6
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• pp.131-133
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• 2011

비단은 비만을 기초로 한 당뇨병의 초기상태이며, 당내량 손상(IGT)은 당대사가 정상과 당뇨병 사이에 있는 아건강 상태를 말한다. 비단의 병인병기와 임상특징은 당내량 손상과 기본적으로 일치한다. 당내량 손상은 비만환자가 비단을 거쳐 당뇨병으로 발병되는 자연발전과정으로 비단과 당내량 손상의 공통적인 발병인소는 비만이며, 그 병리중심은 비위(脾胃)기능실조로 인한 당내량 이상으로 중의(中醫) 증형(證型)에 있어 허실(虛實)변화가 있다. 비단과 비만형 IGT 증후, 병리방면에서의 발생과 발전의 작용을 탐구하여 조기에 중약(中藥)을 사용하면 체중을 감소시키고 더 나아가 당뇨병을 예방하는데 중요한 임상의의가 있다.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.5
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• pp.677-682
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• 2013

Impaired glucose tolerance(IGT) & Impaired fasting glucose(IFG) were standardized in 1979 by the National Diabetes Data Group and the World Health Organization as a risk factor for type 2 diabetes. The main clinical significance of IGT & IFG shows some risk factors on type 2 diabetes, cardiovascular disease and component of the metabolic syndrome. In 1997, the American Diabetes Association(ADA) proposed the new classification and diagnostic criteria for diabetes, which wss striction on the diagnostic baseline of Diabetes from 140 mg/dl to 126 mg/dl. This is because that the early diagnosis and treatments can prevent chronic complications. In the oriental medicine, Gamiyookmigihwang-tang has been using for the treatments of Diabetes including IGT & IFG; however, there have not been enough studies about the effect of the glycemic control objectively. So clinical studies have been performed on a mild DM(Diabetes Mellitus) patient with IGT and IFG in order to investigate whether there is hypoglycemic effect of Gamiyookmigihwang-tang. Prior to the study, for two weeks fasting blood sugar(FBS) and postprandial 2hrs(PP2hrs) glucose were checked. in addition ECG, T-cholesterol, TG, HbA1c levels were measured; then, Gamiyookmigihwang-tang has administrated for 4 weeks. and FBS, PP2hrs, T-cholesterol, TG, HbA1c were measured again after the herb medicine treatment. FBS, PP2hrs glucose levels and other measuring levels (T-cholesterol, TG, HbA1c) were decreased by the administration of Gamiyookmigihwang-tang. Gamiyookmigihwang-tang has hypoglycemic effects on a mild DM patient with IGT and IFG.

• Journal of the Korea Society of Computer and Information
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• v.25 no.2
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• pp.31-39
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• 2020

In this paper, we introduce a technique for generating synthetic benchmarks based on time series data. Many of the data measured on IoT devices have a time series characteristic that measures numerical changes over time. However, there is a problem that it is difficult to model the data measured over a long period as generalized time series data. To solve this problem, this paper introduces the BST-IGT model. The BST-IGT model separates the entire data into sections that can be easily time-series modeled, collects the generated data into templates, and produces new synthetic benchmarks that share or modify characteristics based on them. As a result of making a new benchmark using the proposed modeling method, we could create a benchmark with multiple aspects by mixing the composite benchmark with the statistical features of the existing data and other benchmarks.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.38 no.1 s.113
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• pp.27-33
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• 2006

Newsprint is quantitatively the most important printing paper. The demands for its printability are continuously increasing. It is well known that the relationship between the physically tested paper properties and newspaper printability is unsatisfactory. In order to improve the printing quality of Korean newsprint, the printability coefficients such as maximum ink requirement(Ymax), print through were investigated. Kinds of newspapers and black printing ink were tested by IGT printability tester. Experiment condition of IGT printability tester was 14 steps between $0.2{\sim}2.8g/m^2$ of ink requirement, printing pressure was 200 N and printing velocity was 1 m/sec. The properties of newspaper samples (basis weight, bulk density, roughness, smoothness, porosity, i. e.) were examined in accordance with KS and TAPPI standard testing methods. The result of this study are respected for usefulness printing quality management of Korean newsprint.

• Investigative Magnetic Resonance Imaging
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• v.13 no.2
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• pp.127-136
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• 2009

Purpose : Functional magnetic resonance imaging (fMRI) was used to assess the temporal response of neural activation in healthy subjects while they performed the Iowa Gambling Test (IGT), which utilizes decisions involving ambiguity and risk. The IGT was divided into five blocks of 20 trials; analysis showed that activity in the medial prefrontal cortex (mPFC) moves gradually from the dorsal to the ventral mPFC over the course of the IGT. These findings suggest that cognitive division of the mPFC, including the dorsal portion of the anterior cingulated cortex (ACC), plays a major role in ambiguous decision making and that the aspect of the IGT corresponding to risky decision making is associated with significant activity within the corticolimbic network strongly implicated in emotion and reinforcement. Our results also suggest that decisions made under ambiguity and decisions made under risk situations can be further divided into sub-phases based on the neural network involved.