• Title/Summary/Keyword: Human volunteer

검색결과 119건 처리시간 0.024초

Knowledge, Attitudes and Beliefs about Cervical Cancer and Human Papilloma Virus Vaccination with Related Factors in Turkish University Students

  • Yilmazel, Gulay;Duman, Nuriye Buyukkayaci
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권8호
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    • pp.3699-3704
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    • 2014
  • Background: This study aimed to determine knowledge, attitudes and believes about cervical cancer and human papilloma virus (HPV) vaccination with related factors in Turkish university students. Materials and Methods: This descriptive and cross sectional study was conducted between June-July 2013 in Hitit University located in Corum, a rural area to the East of Ankara. The population consisted of 550 university students who were training in first and last year from Faculties of Economics, Theology and Health. We reached 463 volunteer students without selection. The study of data was collected with a 44 item questionaire covering socio-demographic features, knowledge, attitudes and beliefs about cervical cancer, HPV and vaccination. Also for this study ethic committee report was taken from Bozok University. Data were evaluated with the SPSS 17.0 programme using the Ki kare test with P<0.05 accepted as statistically significant. Results: It was seen that there was a statistically significant variation between classrooms and departments of students with knowledge about cervical cancer and human papilloma virus and vaccine (p<0.001; p<0.01; p<0.05). Also we found low attitudes to thinking about taking HPV vaccination of girls and their children in the future. Conclusions: In light of the study findings; it was concluded that knowledge levels, beliefs and attitudes of the university students about cervical cancer, HPV infection and HPV vaccination were low.

식품중 미생물 위해성평가 방법론 연구 (Study on the Methodology of the Microbial Risk Assessment in Food)

  • 이효민;최시내;윤은경;한지연;김창민;김길생
    • 한국식품위생안전성학회지
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    • 제14권4호
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    • pp.319-326
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    • 1999
  • 최근 국내에서는 Escherichia coli O157:H7, Listeria monocytogenes등의 미생물에 대한 건강위해성이 강조되면서 미생물 위해성평가에 대한 필요성이 제기되고 있고, U.S.FPA, U.S.DA, FAO/WHO를 비롯한 국제기구 및 외국 유관기관들에서도 미생물 위해성평가 방법을 식품관리에 활용하고자 방법론 연구에 주력하고 있다. 미생물 위험성은 화학물질과 달리 인체건강에 대한 영향이 즉각적이고, 심각하게 나타나 정량적인 위해성평가가 용이하지 않고 유해화학물질과는 다른 평가방법이 요구된다. 식품중 미생물의 위해성평가는 크게 4단계로 구분되는데, 미생물관련질환 추세파악 및 미생물 관련질병에 관한 역학조사 등을 활용하는 위험성확인 단계와 실제 식품원료, 식품가공, 수송, 포장단계 중 식품의 물리적, 화학적 조건에 따른 미생물 변화를 고려하여 식품중 미생물에 대한 노출을 정량화하는 노출평가 단계, 미생물의 용량에 따른 질병발생에 근거하여 용량-반응관계를 규명하는 용량-반응평가 단계, 규명된 모델을 활용하여 모든 평가결과를 통합함으로 위해 도치 예측과 불확실성 분석 등을 수행하는 위해도결정단계로 구성되어 있다. 미생물 용량-반응평가는 크게 비역치(Nonthreshold)와 역치(Threshold) 평가 방법론으로 구분되는데, 비역치 평가방법론은 단일 병원균이 감염을 일으킬 수 있다는 것과 감염을 일으킬 수 있는 확률이 독립적이라는 가정을 전제로 하고, 역치평가방법론은 미생물이 감염을 일으키기 위해서 각기 개별 역치가 존재하는데 어느 정도의 미생물수가 모여 서로 작용해야 독성유발물질을 만들어 낸다는 가정을 전제로 한다. 현재 받아들여지고 있는 비역치 모델로는 Exponential, Beta-poisson, Gompertz, Gamma-weibull 모델 등이 있으며, 역치모델로는 Log-normal, Log-logistic모델 등이 있다. 본 연구에서는 인체 volunteer자료를 활용하여 용량-반응자료를 입력하고 용량-반응자료를 토대로 적합한 수학적 모델을 찾아내어, 선별한 모델의 적합도 검정을 실시하는 방법론 연구를 실시하였으며, 노출평가 자료와 용량-반응평가 결과를 연계하여 위해도를 결정하는 과정에 대해 연구하였다 이 밖에도 모델(Food MicroModel)을 이용하여 식품의 염도, 수분활성도, 온도, pH등의 조건에 따른 미생물의 성장률, 사멸률 등 변화를 예측할 수 있는 방법론 연구를 통해 식품의 최적 보관 조건등을 찾아내는 방법을 습득하였다. 미생물 위해성평가는 외국에서도 아직 초기 연구단계에 있으며 현재로서 사후조사자료인 역학자료보다 건강한 성인남자를 대상으로 한 volunteer 자료를 우선적으로 활용하고 있으나 노약자나 민감그룹에 대한 실험은 현실적으로 불가능하여 동물실험을 이용한 평가방법을 연구중에 있다. 추후 연구방향으로는 국내 volunteer들을 대상으로 한 미생물별 용량-반응결과를 토대로 population sensitivity를 비교할 수 있는 기초자료를 확보함으로써 미생물에 대한 인구집단의 반응 민감성 차이를 비교하고 시료채취 후 즉각적인 실험실적 분석이 가능토록하여 정확한 인체노출평가를 수행함으로써 미생물 위해성평가방법론을 식품미생물관리에 적용하는 것이다.

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Development of SD-OCT for Imaging the in vivo Human Tympanic Membrane

  • Cho, Nam-Hyun;Jung, Un-Sang;Kwon, Hyeong-Il;Jeong, Hyo-Sang;Kim, Jee-Hyun
    • Journal of the Optical Society of Korea
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    • 제15권1호
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    • pp.74-77
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    • 2011
  • We report a novel extension of 840 nm wavelength- based spectral domain optical tomography to in vivo/real-time human middle ear diagnosis. The system was designed to access the middle ear region with a specifically dedicated handheld probe. The real-time displaying feature was mandatory for in vivo imaging human subject with the handheld probe, and the system could provide about 20 frames per second for 2048 pixels by 1000 A-scans without using any graphics process units under the Labview platform. The inner ear structure of a healthy male volunteer was imaged with the developed system with the axial and lateral resolutions of $15\;{\mu}m$ and $30\;{\mu}m$, respectively. The application of the OCT technology to early diagnose otitis media(OM) is very promising and could be another extensive branch in the OCT field because it provides the depth resolved image including tympanic membrane (TM) and structures below TM whereas the conventional otoscope technique only gives asurface image of the TM.

저속 후방 추돌 자원자 실험을 통한 두부와 경부의 동작분석 (Motion Analysis of Head and Neck of Human Volunteers in Low-Speed Rear Impact)

  • 홍성우;박원필;박성지;유재호;공세진;김한성
    • 자동차안전학회지
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    • 제4권2호
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    • pp.37-43
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    • 2012
  • The purpose of this research is to obtain and analyze dynamic responses from human volunteers for the development of the human-like mechanical or mathematical model for Korean males in automotive rear collisions. This paper focused on the introduction to a low-speed rear impact sled test involving Korean male subjects, and the accumulation of the motion of head and neck. A total of 50 dynamic rear impact sled tests were performed with 50 human volunteers, who are 30-50 year-old males. Each subject can be involved in only one case to prevent any injury in which he was exposed to the impulse that was equivalent to a low-speed rear-end collision of cars at 5-8 km/h for change of velocity, so called, ${\Delta}V$. All subjects were examined by an orthopedist to qualify for the test through the medical check-up of their necks and low backs prior to the test. The impact device is the pendulum type, tuned to simulate the crash pulse of a real vehicle. All motions and impulses were captured and measured by motion capture systems and pressure sensors on the seat. Dynamic responses of head and T1 were analyzed in two cases(5 km/h, 8 km/h) to compare with the results in the previous studies. After the experiments, human subjects were examined to check up any change in the post medical analysis. As a result, there was no change in MRI and no injury reported. Six subjects experienced a minor stiffness on their back for no more than 2 days and got back to normal without any medical treatment.

온열요법이 면역활성의 변화에 미치는 효과 (Effects of the Heat Therapy on Changes of Immune Activities in Human Body)

  • 이상빈
    • 한국콘텐츠학회논문지
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    • 제9권1호
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    • pp.285-292
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    • 2009
  • 본 연구는 온열요법, 그 중 습열(moist heat)과 건열(dry heat)의 적용이 면역 활성의 변동에 미치는 효과를 알아보기 위한 것이다. 건강에 이상이 없는 연령 23${\sim}$32세, 신장 171.0${\pm}$1.2cm, 체중 68.0${\pm}$2.2kg의 남성 15명과 연령 22${\sim}$24세, 신장 159.5${\pm}$1.2cm, 체중 54.6${\pm}$2.4kg의 여성 15명을 대상으로 인체에 온열침수 (핫팩(KRS 12P, Karis Co., Korea))와 적외선 (발광 적외선등(Infrared, Ilshin Co., Korea))을 적용하여 보체와 같은 면역-활성 물질의 추이를 살펴보았다. 연구의 결과로써, 온열침수와 적외선을 적용한 결과 온열침수와 적외선 적용으로 보체 성분의 변동은 온열침수 적용으로 C1q의 유의한 감소와 C3(여성의 경우) 및 C4의 감소가 나타남을 확인할 수 있었다. 그러나 적외선의 경우 C1q와 C3 및 C4의 증감에 별다른 영향을 미치지 못하였다. 이러한 연구의 결과로 미루어 온열침수의 적용으로 보체계의 활성을 확인할 수 있었으며 이러한 면역-활성의 증가는 선택적 경로(alternative pathway)가 아닌 고전적 경로(classical pathway)를 통해 이루어짐을 추정할 수 있었다. 따라서 본 연구의 결과는 극히 부분적 결과를 나타내지만, 온열침수와 적외선 적용으로 면역-증강효과가 다소 존재하는 것으로 사료된다.

일부 지역 대학생들의 의료봉사 프로그램 개발 (Development directions of voluntarism in University students)

  • 김창규;김미란
    • 한국융합학회논문지
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    • 제2권2호
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    • pp.57-65
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    • 2011
  • 이 연구는 김천대학교 보건계열의 의료봉사 교과목의 운영과 보건복지 임상센터의 물적 인적자원의 효율을 높일 수 있는 방안을 제시하여 의료봉사를 체계적이며 예측가능하게 운영하는데 기여하고자 시도하였다. 이러한 연구결과로부터 얻은 결론은 아래와 같다. 1) 사회봉사 교과목의 운영은 1학점 이상을 교양필수 또는 전공필수로 2학년에 개설하여 학습과 봉사의 혼합 형태로 개설 운영하여야 한다. 2) 의료봉사 활동대상은 독거노인, 고아원 아동, 독거 장애인, 소년소녀가장, 양노원 노인 등이어야 한다. 3) 다양한 프로그램 개발과 봉사학생에 대한 인센티브 제공이 필요하며, 보건복지임상센터는 주 1회 지역소외 계층을 대상으로 운영하여야 한다.

중년1인가구의 혼인상태별 여가시간사용 결정요인 분석 (A study on the determinants of leisure time use by marital status of middle-aged one-person households)

  • 서지원;양진운
    • 가족자원경영과 정책
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    • 제21권3호
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    • pp.77-95
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    • 2017
  • The purpose of this study is to examine the factors related to leisure time to understand middle-aged one-person households. Data are from the recent survey of lifetime use in 2014 by Statistics Korea(N=1,138). Middle-aged one-person households aged 40-59 years were categorized into four groups by marital status (unmarried/married/widowed/divorced). Major results were found as follows: First, the total leisure time per day was 238 min in the middle-aged one-person households. The majority of the total leisure time was spent on 'fellowship & leisure activities'(204 min on weekdays, 283 min on weekends). Especially, time spent on real-time TV watching hours was the longest, as long as 89 min on weekday and 150 min on weekends. Second, gender differences were significant in terms of leisure time use in the middle-aged one-person households. Females spent less time on leisure than their male counterparts on both weekdays and weekends. In addition, gender differences related to marital status were significant. Third, on weekdays, the determinants of leisure time use among the middle-aged one-person households were health and type of employment for 'participation & volunteer activities', and gender, age, marital status, and type of employment variables for 'fellowship & leisure activities.' On weekends, time spent on 'participation & volunteer activities' were influenced by marital status, residential area, and type of employment, while time spent on 'fellowship & leisure activities' were significantly related to gender, type of employment, type of job, holiday system, and income.

The Effects of Heat Application on the Immune Activities of the Human Body

  • Lee, Sang-Bin;Park, Joo-Hyun;Kim, Yong-Nam;Lee, Byoung-Hee;Yoon, Jung-Gyu;Yoo, Kyoung-Tae;Lee, Suk-Hee;Kim, Sung-Joong;Lee, Mi-Joung
    • 국제물리치료학회지
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    • 제1권1호
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    • pp.19-25
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    • 2010
  • The purpose of this study was to determine the effects of heat application on the immune activities of the human body. To exam, furthermore, the immune effect from the healthy volunteer(male:15, female:15) by monitoring changes of immune substances such as various leukocytes[total white blood cell(WBC), eosinophil, neutrophil, basophil, monocyte, and lymphocyte], a comparative study with warm water immersion($40.8{\pm}0.3^{\circ}C$) and infrared(250W) was carried out. The plasma analysis showed that the count of white blood cell, eosinophil, and neutrophil were elevated in warm water immersion- or infrared. stimulated group compared with control group. However, the count of basophil was decreased in both warm water immersion- and infrared-stimulated group than control group. Therefore, these results suggest that the thermostimulation improved immune activity.

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한국 학생의 로봇에 대한 태도: 국제비교 및 태도형성에 관하여 (Korean Students' Attitudes Towards Robots: Two Survey Studies)

  • 신나민;김상아
    • 로봇학회논문지
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    • 제4권1호
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    • pp.10-16
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    • 2009
  • This paper is concerned with Korean students' attitudes towards robots, presenting two survey studies. The first study was concerned with a group of college students, taking the perspective of international comparison. Data were collected by administering an online survey, where 106 volunteer students had participated. In the survey, the Negative Attitude towards Robot Scale(NARS) was adopted to compare the Korean students' scores with those of multi-national groups (U.S.A, Germany, Netherland, Japan, Mexico, and China) who responded to the same scale in Bartneck et al.'s research. The analysis of the data reveals that Korean students tend to be more concerned about social impacts that robots might bring to future society and are very conscious about the uncertain influences of robots on human life. The second study investigated factors that may affect K-12 students' attitudes towards robots, with survey data garnered from 298 elementary, middle, and high school students. The data were analyzed by the method of multiple regression analysis to test the hypothesis that a student's gender, age, the extent of interest in robots, and the extent of experiences with robots may influence his or her attitude towards robots. The hypothesis was partially supported in that variables of a student's gender, age, and the extent of interest in robots were statistically significant with regard to the attitude variable. Given the results, this paper suggests three points of discussions to better understand Korean students' attitudes towards robots: social and cultural context, individual differences, and theory of mind.

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은퇴한 노인의 생활시간 사용에 관한 연구 (A Study on the Time Usage of the Retired Elderly)

  • 이신숙
    • 한국생활과학회지
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    • 제20권2호
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    • pp.311-325
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    • 2011
  • The purpose of this study was to analyze patterns of time usage of the retired elderly so as to improve their quality of life. The subjects of this study were 225 elderly people in Jeonnam Province. The statistics used for data analysis were frequency, percentage, mean, standard deviation, t-test, and multiple regression. The major findings were as follows : (1) The retired elderly spend more time in physiological activities and leisure, and there was no day difference in time use. (2) On weekdays, the variables affecting labor time were age, former job, health state, and education. On the weekends, education, health state, and former job had significant effects on the amount of time spent on labor. (3) The variables affecting participation and volunteer time were: monthly living expenses, age, spouse, former job, and house, on weekdays, and on the weekends, significant factors were spouse, age, and former job. (4) The variables affecting leisure time were education, age, monthly living expenses, religion, and economic state, on the weekdays, and on weekends, the significant factors were education, economic state, house, religion, and former job.