• Title/Summary/Keyword: Human Similarity

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Multiplex PCR-aided Differential Diagnosis of Taeniid Species (Multiplex PCR을 이용한 조충류의 감별진단)

  • Lee, Hye-Jung;Seo, Min;Kwak, Sahng-June
    • Journal of Life Science
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    • v.20 no.6
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    • pp.955-959
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    • 2010
  • Differential diagnosis of the taeniid proglottids between Taenia asiatica and T. sagniata is a daunting task due to their close morphological similarity. However, to correctly diagnose them on time is important in managing infected patients, as well as for reducing serious complications such as cysticercosis. Currently, DNA-based methods for the dissection of genomic information of parasites are being employed to make accurate and rapid diagnoses in the field of parasitology. In this study, multiplex PCR was established and exploited to identify exact species of taeniid adult worms recovered from Korean people. To discriminate one from the other other, primers-Ta4978F, Ts5058F, Tso7421F, and Rev7915- were used for the multiplex PCR, which provided swift and precise identification of the taeniid worms being observed. Also,having instituted PCR methodology, we ascertained that easiness would be achieved to reassess and re-evaluate Korean endemic data on human taeniid cestodes.

Transient Diagnosis and Prognosis for Secondary System in Nuclear Power Plants

  • Park, Sangjun;Park, Jinkyun;Heo, Gyunyoung
    • Nuclear Engineering and Technology
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    • v.48 no.5
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    • pp.1184-1191
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    • 2016
  • This paper introduces the development of a transient monitoring system to detect the early stage of a transient, to identify the type of the transient scenario, and to inform an operator with the remaining time to turbine trip when there is no operator's relevant control. This study focused on the transients originating from a secondary system in nuclear power plants (NPPs), because the secondary system was recognized to be a more dominant factor to make unplanned turbine-generator trips which can ultimately result in reactor trips. In order to make the proposed methodology practical forward, all the transient scenarios registered in a simulator of a 1,000 MWe pressurized water reactor were archived in the transient pattern database. The transient patterns show plant behavior until turbine-generator trip when there is no operator's intervention. Meanwhile, the operating data periodically captured from a plant computer is compared with an individual transient pattern in the database and a highly matched section among the transient patterns enables isolation of the type of transient and prediction of the expected remaining time to trip. The transient pattern database consists of hundreds of variables, so it is difficult to speedily compare patterns and to draw a conclusion in a timely manner. The transient pattern database and the operating data are, therefore, converted into a smaller dimension using the principal component analysis (PCA). This paper describes the process of constructing the transient pattern database, dealing with principal components, and optimizing similarity measures.

Characterization and Expression Pattern of the Partial Myostatin cDNA in Shrimp, Fenneropenaeus chinensis

  • Lee, Sang Beum;Kim, Yong Soo;Yoon, Moongeun;Kim, Su-Kyoung;Jang, In Kwon;Lim, Hyun Jeong;Jin, Hyung-Joo
    • Journal of Marine Bioscience and Biotechnology
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    • v.2 no.4
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    • pp.224-229
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    • 2007
  • Muscle tissue expresses many muscle-specific genes, including myostatin (also known as GDF8) that is a member of the transforming growth factor-beta superfamily. Myostatin (MSTN) negatively regulates mammalian skeletal muscle growth and development by inhibiting myoblast proliferation. Mice and cattle possessing mutant MSTN alleles display a 'double muscling' phenotype characterized by extreme skeletal muscle hypertrophy and/or hyperplasia. In this study, we first have characterized partial cDNA of a MSTN gene from the muscle tissue in the F. chinensis and examined its expression pattern in various tissues. The partial MSTN gene (GenBank accession number EU 131093) in the F. chinensis was 1134 bp, encoding for 377 amino acids that showed 63-93% amino acid similarity to other vertebrate MSTNs, containing a conserved proteolytic cleavage site (RXRR) and conserved cysteine residues in the C-terminus. Based on a RT-PCR, the MSTN gene was expressed in the all tissues of F. chinensis used in this study.

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Iris Recognition Using the 2-D Gabor Filter (2-D Gabor 필터를 이용한 홍채인식)

  • Go, Hyoun-Joo;Lee, Dae-Jong;Chun, Myung-Geun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.13 no.6
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    • pp.716-721
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    • 2003
  • This paper deals with the iris recognition as one of biometric techniques which are applied to identify a person using his/her behavior or congenital characteristics. The iris of a human eye has a texture that is unique and time invariant for each individual. First, we obtain the feature vector from the 2D iris pattern having a property of size invariant and divide it into 24 sectors which are further through three types of 2D Gabor filters. At the recognition process, we compute the similarity measure based on the correlation values. Here, since we use three different matching values obtained from three different directional Gabor filters and select the maximum value among them, it is possible to minimize the recognition error rate. To show the usefulness of the proposed algorithm, we applied it to a biometric database consisting of 50 iris patterns extracted from 10 subjects and finally get more higher than 90% recognition rate.

A Study on the Tattoo Represented in the Modern Western Costumes (현대 서양복식에 나타난 TATTOO에 관한 연구)

  • 이효진
    • The Research Journal of the Costume Culture
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    • v.7 no.4
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    • pp.52-68
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    • 1999
  • The purpose of this study was to be inquired inner contemplation of the tattoo expressed in the modern costumes. For this study, related documentaries and pictures or photos were analyzed in terms of the theretical background for the history of tattoo, the relation between tattoo and the modern western costumes. The primary source of pictures or photos are Vogue, Collections, Collezioni, Harper\`s Bazaar, Modain, Model et Mode etc. The human\`s needs of body decoration had constantly pursued on the body and costumes from the first until lately. Especially in the recents, as the tattoo is implicated a dynamic and charming method of all kinds of body decoration, it\`s used a motive of modern western costumes. The original tattoo means a picture, word etc. that was put permanently onto their skin using a needle and coloring matter. But, these days tattoo is an expression of street style for something new in the subculture. The results were as a follows : The inner meaning of tattoo represented in the modern costumes was classified into two categories. First, the tattooing was a very important factor to complete fashion design through the history of modern costumes, and also the elaborate tattoo of the body was displayed unrestricted formativeness as the skinhead\`s tattoo, raceless\`s ambiguity of street style and artistic decoration, because that can be faded easily. Second, Tattoo Look was expressed as tattoo prints of the see-through, elastic textiles in the modern costumes. That is, the tattoo enhanced the effect of dramatic atmosphere other formative arts as well as the modern costumes by Tattoo Look. Similarity, Tattoo Look could be interpreted as the change of the aesthetic consciousness by the influence of the subculture. Accordingly, in the end of a this century, many experimental designers had applied tattoo to modern costumes. So this study will stand as an important clue to foresee the future costume\`s style and change.

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In silico Analysis on hERG Channel Blocking Effect of a Series of T-type Calcium Channel Blockers

  • Jang, Jae-Wan;Song, Chi-Man;Choi, Kee-Hyun;Cho, Yong-Seo;Baek, Du-Jong;Shin, Kye-Jung;Pae, Ae-Nim
    • Bulletin of the Korean Chemical Society
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    • v.32 no.1
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    • pp.251-262
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    • 2011
  • Human ether-a-go-go related gene (hERG) potassium channel blockade, an undesirable side effect which might cause sudden cardiac death, is one of the major concerns facing the pharmaceutical industry. The purpose of this study is to develop an in silico QSAR model which uncovers the structural parameters of T-type calcium channel blockers to reduce hERG blockade. Comparative molecular similarity indices analysis (CoMSIA) was conducted on a series of piperazine and benzimidazole derivatives bearing methyl 5-(ethyl(methyl)amino)-2-isopropyl-2-phenylpentanoate moieties, which was synthesized by our group. Three different alignment methods were applied to obtain a reliable model: ligand based alignment, pharmacophore based alignment, and receptor guided alignment. The CoMSIA model with receptor guided alignment yielded the best results : $r^2$ = 0.955, $q^2$ = 0.781, $r^2_{pred}$ = 0.758. The generated CoMSIA contour maps using electrostatic, hydrophobic, H-bond donor, and acceptor fields explain well the structural requirements for hERG nonblockers and also correlate with the lipophilic potential map of the hERG channel pore.

The Basic Study of Integration for Family Welfare Delivery System : Focused on Healthy Family Support Centers and Multicultural Family Support Centers (가족복지전달체계 통합을 위한 기초연구 : 건강가정지원센터와 다문화가족지원센터를 중심으로)

  • Lee, Seong-Mie;Song, Hyerim;Ra, Hui-Mun;Park, Jeong-Yoon
    • Journal of Families and Better Life
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    • v.30 no.5
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    • pp.1-15
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    • 2012
  • The purpose of this study is various discussion and alternatives focusing on integration of center for enhancing family policy delivery system and family support service the long term. The subject is managers who work at Healthy Family Support centers and Multicultural Family Centers. And they are responded non-structural questionnaire. The results were follows: First, 82.4% respondents of healthy support center and 50% respondents were in favor of integration. Second, reason of integration are conformance for social integration, the efficiency of center operations, the adequacy of program for various family, doing program with the goal of both centers of the similarity, complementary, and user convenience, prevent duplication and missing of services and so on, If the amount charged against the project of the center dissimilarity of institutions, including the operating direction was different. Third, the Center for the meaning of integration are name, organization, reorganization or consolidation of functions, was regarded as entrusted to corporate consolidation. Fourth, the consolidation that occurs during problem solving to ensure the succession of budgeting and human resources and program alternative for dressing up, commissioning center was the difference as problem solving.

Food Consumption Patterns of First Generation Korean-Americans in Hawaii

  • Han, ji-Sook
    • Preventive Nutrition and Food Science
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    • v.3 no.1
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    • pp.77-84
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    • 1998
  • To evaluate food consumption patterns of first generation Korean-American in Hawaii, questionnaires were developed using sociodemographic questions and food frequency questionnaire, which included 139 food items most often consumed among Korean foods and American foods. The questionnaires surveyed 157 first generation Korean-Americans in Hawaii. Mean daily servings for the first generation Korean-Americans were calculated for 139 food items combined into 41 food groups based on similarity in nutrient composition and serving size. The food groups which were consumed in amounts over one serving per day for all subjects were rice, Kimchi , non-citrus fruit , vegetables, organge/green vegetables. oil. margarine and coffee/tea. All subjects consumed less than one serving of hotdogs, hamburgers, pizza and pancakes per week(0.14 serving per day). The most notable characteristic of food consumption for first generation Korean-Americans was that they consumed more Korean food such as rice, Kimchi, soybean paste(Deenjang), soybean curd and seaweed than American foods. Compared with other groups based on age and gender, younger men showed significantly(p<0.05) more frequent consumption of beef/pork, sausages /hams /bacons and hambergers. Older men were significantly(p<0.05) more likely to consume Doenjang and less likely to consume pizza and hamburgers. Daily servings were below the recommended level for thegrains /bread/cereals group and fats/oils/sweets group for all subjects . Fruits/vegetables group servings exceeded the recommeded 5 daily servings for younger men. In correlations of daily servings of selected foods among Korean foods and American food with sociodemographic characteristics, this study showed that the older the subjects and the shorter the stay in Hawaii, subjects were more likely to consume Kroean foods.

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Phylogeny of Mite Taxa (Acari : Sarcoptiformes) Based on Small Subunit Ribosomal RNA Sequences (리보솜 Small unit RNA 염기서열을 이용한 진드기류(Acari:Sarcoptiformes)의 분류)

  • Lee Keun Hee;Yu Hak Sun;Park Sang Kyun;Lee Sun Joo;Lee Kyeong Ah;Kim Sun Mee;Ock Mee Sun;Jeong Hae Jin
    • Journal of Life Science
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    • v.16 no.1
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    • pp.71-75
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    • 2006
  • We analyzed the phylogenic relationships of 23 partial 18S rDNA sequences of 22 species (1 species has 2 strains) belonging to Sarcorptiforms include 4 new sequences, using several tools. Although geographic distributions are quite far from, sequence similarity of two strains of Dermatophygoides pteronyssinus isolated from Japan and New Zealand were very high. This result suggests that mite migration by animals including human occurred in the two continents. We investigated the Endeostigmata taxonomic relationship between the Prostigmata and Oribatida subgroups using small fragments (340-400 bp) of their 185 rDNA sequences. But Endeostigmata was not grouped with Oribatida or Prostigmata. In conclusion, it is first reported phylogenic relationship for classified mites included in Sarcoptiformes using 185 rDNA sequence analysis and its system is a very powerful tool for classification of mites.

Phytosociological Studios on Natural Vegetation in Hoo-Won, Changduk Palace (창경궁 후원 자연식생의 식물사회학적 연구)

  • 오구균;이경재
    • Journal of the Korean Institute of Landscape Architecture
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    • v.14 no.2
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    • pp.27-42
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    • 1986
  • The vegetation structure in the Hoo - Won, Changduk Palace in Seoul was analysed on 10 sites sampled for understanding structure of natural vegetation. The main vegetational survey was conducted during July, 1985 and actual vegetaion and degree of natural vegetaion types were surveyed additionally. The result summarized of this research are as follows. 1) The physical - chemical conditions of soil showed middle class. This might be derived by short succession period from Pine forest to decidious broadleaf forest and artificial impact by human intervention. 2) When considering dominance species by crown story, Quercus aliena was a dominant species over all site and Castanea crenata, Prunus sargentii and Quercus variabilis appeared as a dominant species locally at upper story. Styrax story and Rhododendron mucronulatum, Styrax japonica, Stephanandra incisa and Lespedeza spp. at lower story. 3) The distances kept by trees per crown story are as follows. The mean distances between trees were 4.5-5.5m at upper story, 2.8-3.3m at middle story. On the other hand, the mean distances between dominant species were 6-8m at upper story, 5-9m at middle story. 4) The vegetation in this area was not developed yet into dominant species community according to the similarity analysis. The natural vegetation was dominated by Quercus spp. especially Quercus aliena according to the analysis of species diversity, relative dominance by story and DBH class. On the orther hand, succession to climax stage dominated by shade tolerent species will take a long time due to little appearance of shade tolerence species by previous heavy artificial impacts on understory species. 5) Quercus forest took possesion of 71.3%(27.37ha) of total forest area when considering the actual vegetation and especially Quercus aliena community covered 53.2%(15.21ha). Carpinus laxiflora community, one of the climax species in temperate zone, took possesion of 1.0%(0.3ha) and Pine densiflora was almost disappeared due to species competition. 6) According to the degree of natural vegetation types, the possession of degree of 6-9 was 60.6% and degree of 7-8, substitute vegetation, was 15.5%. The possesion of degree of 9 which consists of over 50 years old trees simliar to natural vegetaion was the highest, 43.1% in this area. Therefore continuous protection in this area of degree of 9 should be recommended.

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