• 한국철도학회:학술대회논문집
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• 한국철도학회 2006년도 추계학술대회 논문집
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• pp.1529-1535
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• 2006

Human error is one of the major contributors to the railway accidents or incidents. In order to develop an effective countermeasure to remove or reduce human errors, a systematic analysis should be preferentially performed to identify their causes, characteristics, and types of human error induced in accidents or incidents. This paper introduces a case study for human error analysis of the railway accidents and incidents. For the case study, more than 1,000 domestic railway accidents or incidents that happened during the year of 2004 have been investigated and a detailed error analysis was performed on the selected 90 cases, which were obviously caused by human error. This paper presents a classification structure for human error analysis, and summarizes the analysis results such as causes of the events, error modes and types, related worker, and task type.

• Journal of Microbiology and Biotechnology
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• 제23권5호
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• pp.689-698
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• 2013

The production and characterization of an active recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) in Escherichia coli BL21(DE3) has been previously reported. In this study, the effect of the signal peptide (SP), inducer concentration, process scale, and operational mode (batch and semi-continuous) on GALNS production were evaluated. When native SP was presented, higher enzyme activity levels were observed in both soluble and inclusion bodies fractions, and its removal had a significant impact on enzyme activation. At shake scale, the optimal IPTG concentrations were 0.5 and 1.5 mM for the strains with and without SP, respectively, whereas at bench scale, the highest enzyme activities were observed with 1.5 mM IPTG for both strains. Noteworthy, enzyme activity in the culture media was only detected when SP was presented and the culture was carried out under semi-continuous mode. We showed for the first time that the mechanism that in prokaryotes recognizes the SP to mediate sulfatase activation can also recognize a eukaryotic SP, favoring the activation of the enzyme, and could also favor the secretion of the recombinant protein. These results offer significant information for scaling-up the production of human sulfatases in E. coli.

• 대한안전경영과학회지
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• 제10권4호
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• pp.65-72
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• 2008

The Manchester Driver Behavior Questionnaire (DBQ) is the most commonly used frameworks for investigating the relationship between self-reported driving behavior and accident involvement. After Reason et al. introduced DBQ, there were many studies replicating the research of Reason et al. in many countries. There was, however, no study replication of the Reason's research in Korea. The aim of this study is to replicate the distinction among errors, lapses and violations, and to evaluate the relationship of these behaviors with road traffic accidents on Korean drivers. 223 Korean drivers completed the Korean version of original DBQ with questions regarding background information, such as age, gender, annual mileage and accident involvement. Participants answered self-assessment questions, also. Factor analysis revealed three factors like Reason et al. The three factors were dangerous errors, violations and relatively harmless errors.

• 대한인간공학회:학술대회논문집
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• 대한인간공학회 1996년도 추계학술대회논문집
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• pp.125-140
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• 1996

Human Factors Engineering(HFE) program should be developed from the early stage of the design process for Nuclear Power Plant. The HFE program is conducted in accordance with the guidance in the Standard Review Plan(SRP) NUREG 0800, Chapter 18. The major purpose of this program is to reduce the incidence of human error during the operating life of the plants. A comprehensive human factors program is prepared by KOPEC to assure that key elements of human factors involvement are not inadvertently overlooked and the early, complete, and continuing inclusion of HFE in the design process. This paper is to introduce engineering steps of the HF activities to verify that the HF involvements on man-machine interface are adequate to support safe and efficient operation of nuclear power plant. If systems are developed without sufficient consideration on the HFE in the design, such systems may cost a high price due to the malfunction of the plant induced by the human errors.

• Genomics & Informatics
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• 제12권4호
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• pp.136-144
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• 2014

Besides single-nucleotide variants in the human genome, large-scale genomic variants, such as copy number variations (CNVs), are being increasingly discovered as a genetic source of human diversity and the pathogenic factors of diseases. Recent experimental findings have shed light on the links between different genome architectures and CNV mutagenesis. In this review, we summarize various genomic features and discuss their contributions to CNV formation. Genomic repeats, including both low-copy and high-copy repeats, play important roles in CNV instability, which was initially known as DNA recombination events. Furthermore, it has been found that human genomic repeats can also induce DNA replication errors and consequently result in CNV mutations. Some recent studies showed that DNA replication timing, which reflects the high-order information of genomic organization, is involved in human CNV mutations. Our review highlights that genome architecture, from DNA sequence to high-order genomic organization, is an important molecular factor in CNV mutagenesis and human genomic instability.

• 대한인간공학회지
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• 제20권2호
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• pp.1-28
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• 2001

This paper deals with the selection of the important Influencing Factors (IFs) under accident management situations in nuclear power plants for use in the assessment of human errors. In order to achieve this goal, we collected two types of IF taxonomies, one is the full set IF list mainly developed for human error analysis. and the other is the IFs for human reliability analysis (HRA) in probabilistic safety assessment (PSA). Five sets of IF taxonomy among the full set IF list and ten sets of IF taxonomy among HRA methodologies were collected in the study. From the review and analysis of BRA IFs, we could obtain some insights for the selection of HRA IFs. By considering the situational characteristics of the accident management domain, candidate IFs are chosen. Finally, those IFs are structured hierarchically to be appropriate for the use in the assessment of human error under accident management situation. Three nuclear accidents such as TMI. Chernobyl and JCO were analysed to validate the proposed taxonomy.

• 대한인간공학회지
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• 제30권1호
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• pp.87-98
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• 2011

In this study, we investigated and identified criterial human factors(errors), most of which lead to terrible ship accidents such as collisions, sinking, fire and explosions resulting both in human lives and physical damages to ships as well as surrounding environments. To this end, we went through the accident reports of 413 cases over 2005~2009 period and classified the human factors into 6 major factors with 19 sub ones which were constructed in hierarchical order. The relative importance of major factors was calculated and among others the lack of awareness turned out to be the most important factor with the weight of 0.391. The contributions of the results in the research are two fold: it will help (i) identify the root causes of ship accidents and prevent further potential ship related incidents, (ii) analyze the degree of the risk associated with the ship accidents, when risk analysis is performed.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2006년도 추계학술대회 논문집
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• pp.1082-1087
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• 2006

Human factors still plays a significant role in railway accidents. The accidents often resulted from multiple causes of hardware failures and human errors. So to ensure the safety of railway operations, human error should be effectively prevented and managed. Among several factors influencing human performance, task load (or task complexity) is well known as a major contributor to human error. In order to reduce the potential of human error, a systematic analysis should be undertaken to evaluate task load and to reduce it by modifying task process and/or education&training. In this paper, we proposed a systematic framework for railway industry to perform task analysis and to evaluate task load, and applied it to KTX operational tasks. According to the application study, we identified 14 generic task types of KTX operation. And also this paper shows the quantitative task load of those generic tasks which were analyzed by NASA-TLX method.

• 한국항해학회지
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• 제23권4호
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• pp.29-42
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• 1999

In the recent past, maritime safety research has been applied primarily to technological requirements and progression of regulations on standards of safety from which the ISM Code has resulted. Despite the engineering and technological innovations, significant marine casualties continue to occur, which indicates that human factors are an area requiring more focused attention. This paper aims to study the clear concept and its details of human factors in ship operating system through the investigation of researches presented so far. The purpose of studying human factors is to identify how the crew, the owners, the classification societies, and the regulatory bodies can work together to sever the chain of errors which are associated with every marine casualty. The human factors in ship operating system may be defined as the study and analysis of the interaction between the operator and system variables composing the system, most importantly the procedures and the crew and management follow.

• 한국컴퓨터정보학회논문지
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• 제25권9호
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• pp.143-150
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• 2020

본 연구는 다중위해사례를 중심으로 경호임무수행 간 출입통제 활동을 실시하는 과정에서 유발되는 경호원의 휴먼에러가 무엇인지 규명하고 그에 따른 대책을 제시하는데 목적이 있다. 이를 검증하고자 사건의 순서를 시계열로 배열한 뒤 변동노드를 중심으로 문제점을 파악할 수 있는 'VTA 기법'과 'Why-Why 분석 기법'을 활용하였으며, 추가적으로 'M-SHEL Matrix'를 통하여 휴먼에러를 유발하는 환경요인과 개인요인을 추출하였다. 분석결과, 출입통제 사고를 유발하는 경호환경요인으로는 시간부족(조급함), 방문자에 대한 편견, 편중된 근무방법, 보안 관리미흡, 무사안일주의, 익숙한 분위기(긴장이완), 형식적인 근무활동, 편의제공, 과소평가 등으로 조사되었다. 그리고 경호원 개인적 측면에서 유발되는 휴먼에러는 낮은 경계의식, 형식적인 근무, 검측소홀, 안일한 대처 등으로 조사되었다.