• 제목/요약/키워드: Human Capability

검색결과 688건 처리시간 0.033초

Molecular Cloning, Identification and Characteristics of a Novel Isoform of Carbamyl Phosphate Synthetase I in Human Testis

  • Huo, Ran;Zhu, Hui;Lu, Li;Ying, Lanlan;Xu, Min;Xu, Zhiyang;Li, Jianmin;Zhou, Zuomin;Sha, Jiahao
    • BMB Reports
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    • 제38권1호
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    • pp.28-33
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    • 2005
  • A gene coding a novel isoform of carbamyl phosphate synthetase I (CPS1) was cloned from a human testicular library. As shown by cDNA microarray hybridization, this gene was expressed at a higher level in human adult testes than in fetal testes. The full length of its cDNA was 3831 bp, with a 3149 bp open reading frame, encoding a 1050-amino-acid protein. The cDNA sequence was deposited in the GenBank (AY317138). Sequence analysis showed that it was homologous to the human CPS1 gene. The putative protein contained functional domains composing the intact large subunit of carbamoyl phosphate synthetase, thus indicated it has the capability of arginine biosynthesis. A multiple tissue expression profile showed high expression of this gene in human testis, suggesting the novel alternative splicing form of CPS1 may be correlated with human spermatogenesis.

감성 상호작용을 갖는 교육용 휴머노이드 로봇 D2 개발 (Design and implement of the Educational Humanoid Robot D2 for Emotional Interaction System)

  • 김도우;정기철;박원성
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 제38회 하계학술대회
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    • pp.1777-1778
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    • 2007
  • In this paper, We design and implement a humanoid robot, With Educational purpose, which can collaborate and communicate with human. We present an affective human-robot communication system for a humanoid robot, D2, which we designed to communicate with a human through dialogue. D2 communicates with humans by understanding and expressing emotion using facial expressions, voice, gestures and posture. Interaction between a human and a robot is made possible through our affective communication framework. The framework enables a robot to catch the emotional status of the user and to respond appropriately. As a result, the robot can engage in a natural dialogue with a human. According to the aim to be interacted with a human for voice, gestures and posture, the developed Educational humanoid robot consists of upper body, two arms, wheeled mobile platform and control hardware including vision and speech capability and various control boards such as motion control boards, signal processing board proceeding several types of sensors. Using the Educational humanoid robot D2, we have presented the successful demonstrations which consist of manipulation task with two arms, tracking objects using the vision system, and communication with human by the emotional interface, the synthesized speeches, and the recognition of speech commands.

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가금인플루엔자 바이러스의 인체 감염 가능성 (The Possibility of Avian Influenza Virus Infection in Human)

  • 모인필;하봉도;송창선;김재홍
    • 한국가금학회지
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    • 제31권2호
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    • pp.109-118
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    • 2004
  • Avian influenza(AI) is an epizootic disease of variable severity caused by type A influenza viruses of the orthomyxovirus group. Chickens were the most frequently affected avian species with AI viruses. There were many outbreaks of fowl plague, now known as highly pathogenic AI(HP AI), throughout the world since Perroncito described the fowl plague in 1978 in Italy. In recent years HPAI viruses of different serotypes such as H5, H7 and H9 has been isolated from humans on several occasions either related with outbreak of HPAI in birds or not. In 1997, one of the most noteworthy events in AI history was the human mortality with H5N1 HPAI virus infection in Hong Kong. Six persons of total 18 persons with clinical signs of influenza were died. Recently the human cases with mortality related with HP AI outbreaks in poultry industry has been increased such as outbreaks of HP AI throughout Asia countries including Korea, Japan, China, Vietnam, Thailand and others in 2003. Although these outbreaks revealed the capable of spreading from birds to human, the capability for transmission between people was not clear. Therefore, this report will review the possibility of HP AI infection in human associated with HPAI outbreak in poultry industry.

Establishment and Characterization of Immortalized Human Dermal Papilla Cells Expressing Human Papillomavirus 16 E6/E7

  • Seonhwa Kim;Kyeong-Bae Jeon;Hyo-Min Park;Jinju Kim;Chae-Min Lim;Do-Young Yoon
    • Journal of Microbiology and Biotechnology
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    • 제34권3호
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    • pp.506-515
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    • 2024
  • Primary human dermal papilla cells (HDPCs) are often preferred in studies on hair growth and regeneration. However, primary HDPCs are limited by their reduced proliferative capacity, decreased hair induction potential, and extended doubling times at higher passages. To overcome these limitations, pTARGET vectors containing human papillomavirus16 (HPV16) E6/E7 oncogenes were transfected into HDPCs and selected using G-148 to generate immortalized cells here. HPV16 E6/E7 oncogenes were efficiently transfected into primary HDPCs. Immortalized HDPC showed higher proliferative activity than primary HDPC, confirming an increased proliferation rate. Expression of p53 and pRb proteins was downregulated by E6 and E7, respectively. E6/E7 expressing HDPC cells revealed that cyclin-dependent kinase (CDK) inhibitor p21 expression was decreased, while cell cycle-related genes and proteins (CDK2 and cyclin E) and E2F family genes were upregulated. Immortalized HDPCs maintained their responsiveness to Wnt/β-catenin pathway and hair follicle formation capability, as indicated by their aggregative properties and stemness. E6/E7 immortalized HDPCs may facilitate in vitro hair growth and regeneration studies.

SW 공학수준과 SW 프로젝트 납기성과와의 관계 (Evaluation on the Relationship between Software Engineering Level and Schedule Deviation in Software Development)

  • 김승권;고병선
    • 한국IT서비스학회지
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    • 제10권4호
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    • pp.191-204
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    • 2011
  • Recently, many software companies are trying to improve the software quality and project outcome with more costs and efforts in development time. In the software convergence and integration environments, it is required efforts to gain high quality of software. In other words, it is required to utilize software engineering knowledge and technology for higher software quality and better software project productivity. The Software development productivity can be varied by software process capability according to building a framework for software development, selection and use of appropriate technology, human resource management. Software process capability will influence software project outcome which is the general opinion. This study provides empirical evidence about software engineering efforts and investment approach to lead software project performance. We measured the software engineering efforts by SW engineering level and analyzed the corelation between software engineering level and schedule deviation. And, we verified that this performance is affected by the size of software company. As a result, software process capability is important to build a infrastructure and develop systematically software project. The higher software engineering level can lead to improved software project performance.

포화 저항망을 이용한 광적응 윤곽 검출용 시각칩 (A light-adaptive CMOS vision chip for edge detection using saturating resistive network)

  • 공재성;서성호;김정환;신장규;이민호
    • 센서학회지
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    • 제14권6호
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    • pp.430-437
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    • 2005
  • In this paper, we proposed a biologically inspired light-adaptive edge detection circuit based on the human retina. A saturating resistive network was suggested for light adaptation and simulated by using HSPICE. The light adaptation mechanism of the edge detection circuit was quantitatively analyzed by using a simple model of the saturating resistive element. A light-adaptive capability of the edge detection circuit was confirmed by using the one-dimensional array of the 128 pixels with various levels of input light intensity. Experimental data of the saturating resistive element was compared with the simulated results. The entire capability of the edge detection circuit, implemented with the saturating resistive network, was investigated through the two-dimensional array of the $64{\times}64$ pixels

Analysis of the Changes in the Perceived Important Capabilities of Construction Project Managers after the Global Financial Crisis

  • Lee, Na-Kyung;Bae, Ju-Lee;Jang, Hyoun-Seung
    • Journal of Construction Engineering and Project Management
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    • 제2권3호
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    • pp.8-16
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    • 2012
  • After the 2008 global financial crisis, the construction environment in South Korea continued change in the construction environment. Construction orders in 2011 have shown a downward trend compared with the previous year. Along with these changes in the construction market, the professional capabilities of construction project managers that are perceived as important also changed after the global financial crisis. Accordingly, this study was conducted to identify the major business capabilities of the current construction project managers and to determine which of these capabilities have undergone changes in terms of the importance accorded to them after the global financial crisis, and ultimately, to derive the construction project manager capability areas that need to be strengthened according to the changes in the construction environment. The capabilities of construction project managers were surveyed at two different time points: in 2007 and in 2010. The results show that the year 2010, after the global financial crisis, an increase in the perceived important capabilities of construction project managers compared with 2007. This results the impact of the changes in the construction environment on the importance of construction project managers. This study derived the ramifications of the early identification of systems and prospects according to the changes in the construction circumstances on more efficient onsite and human resources management, by considering the appropriate capabilities of the construction project managers.

영국 풍경식 정원가 의 스타일에 관한 연구 - 설계 특성과 미적 평가를 중심으로 - (Capability Brown and His Landscape Gardening Style-with reference to the character in design and aesthetics-)

  • 방경란;최기수
    • 한국조경학회지
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    • 제26권3호
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    • pp.267-277
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    • 1998
  • The background of this study is to provide meaning of landscape history and to find out landscape origines which were strongly concerned with the nature through breaking out the form of conventional adapting elements from an exterior. And the purpose of this study is to review Brown's philosophy as picturesque landscape architectur and to provide useful Brown's characteristics to contemporary landscape by epitomizing his design elements. Brown estiablished a foundation of the English landscape garden of the eighteenth century. And the concept, the beauty of nature, is considered as a beginning point of modernism study. The study of the Brownian style as profoundity theme is conversion view to the development of the history of garden. These days, the restoration of the Brownian style at the public or garden design in England is based on the nature recourse of the original character of human. And also his style can be understood to seek the progressive transformation as to perfectly known the possibility of the place, to get clues to the solutions, and to be able to iprove the quality of environment. Therefore, Brown's efforts for seeding the essence of landscape architecture escaping from Englands old-fashioned landscape design skills might be considered in high worth.

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The Urgency of Business Agility During COVID-19 Pandemic: Distribution of Small and Medium Business Products and Services

  • BONGSO, Gromyko;HARTOYO, Rachmat
    • 유통과학연구
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    • 제20권6호
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    • pp.57-66
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    • 2022
  • Purpose: Business agility is an important key to survival for SMEs in Indonesia, especially during the COVID-19 pandemic. Indonesian local product distribution and service distribution are mostly served by SMEs. Agile businesses will be able to assist them in the proper distribution of products and services. This research examines how the direct and indirect influence of IT capabilities on business agility through organizational learning and business intelligence for small and medium enterprises in the distribution of Indonesian products and services. Research design, data and methodology: This research uses SEM method with SmartPLS tool. The sample of this research was conducted on small and medium enterprises in the distribution of Indonesian products and services. The sample obtained in this study was 202 SME owners or managers (strategic level). Results: Business intelligence plays a key role in improving business agility. The results of IT capability can directly and indirectly affect business agility through organizational learning. Conclusions: Business intelligence has the biggest role in increasing business agility in SMEs in Indonesia. IT capability has an indirect effect on business agility through organizational learning. The findings of this study prove that IT capabilities do not indirectly affect business agility through business intelligence.

실시간 주관적 감성 평가시스템을 이용한 긍정 및 부정 시각자극에 대한 연구 (A Study on Positive and Negative Visual Stimuli using the Real-Time Human Sensibility Assessment System)

  • 민병찬;정순철;민병운;신미경;정학기;김철중
    • 대한인간공학회지
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    • 제20권1호
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    • pp.31-43
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    • 2001
  • The present study the feasibility of the new subjective assessment devise; Real-Time Subjective Assessment Digitizer (RTSAD). The subjects were instructed to evaluate their sensibility during the presentation of the positive and the negative visual stimuli using RTSAD. After the presentation of each of the stimulus, a questionnaire was used for comparing the results with those from RTSAD. It was argued that the biggest utility of the RTSAD is the capability of measuring and figuring out the trends of the subjective assessment in real time. The results from the questionnaires unlike the results from RTSAD, reflects only the averaged human sensibility for the entire time of the presentation of the stimulus.

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