• Title/Summary/Keyword: Human Body Information

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cDNA microarray gene expression profiling of melittin and mast cell degranulation peptide in human mast cell strain (봉독의 주요성분인 Melittin과 MCDP이 비만세포주에서 유전자 발현에 미치는 영향에 대한 microarray 분석)

  • So, Jae-jin;Woo, Hyun-su;Kim, Chang-hwan
    • Journal of Acupuncture Research
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    • v.22 no.3
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    • pp.37-51
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    • 2005
  • Mast cell is a cell that functions mainly in our body with a respect to inflammation and allergic response. Bee venom has been progressed in a study as a model related to mechanism in alleviation of pain until now, but it is being progressed in a study relevant to immunocyte in anti-inflammation or anti-allergic response. The present study is aimed to present the basis related to a future study of gene, by researching the influence of melittin and MCD Peptide, which are major ingredients in Bee venom, upon the expression of gene in the mast cell strain. In this study, it dealt with melittin and MCD Peptide respectively, in the effective concentration after passing though the experiment of cytotoxicity by using human mast cell strain. Also, with the respect in the aspect of expression in gene that changes at this time, information was obtained through the technique of analyzing microarray. Through experimental statistics, when regarding a case that global M is significant in more than 1 or -1, in melittin, all 7 genes were accelerated, and 8 inhibited. In MCDP, 7 genes were accelerated and 17 genes inhibited. The function in the body to which these genes are related, was associated with the protein binding within a cell, the activation in the function of lymphocyte, the acceptor related to macrophage antigen. In cell nucleus, substance related to GABA A receptor, protein associated with cAMP reactive element, substance related to complement system No.8 and to B-cell, protein substance related to polycystic kidney disease, substance related to inflammation, and the protein substance of influencing coagulation of blood. Through these results of analysis, it could obtain more useful materials in clarifying the mechanism of action in melittin and MCD peptide, which are in charge of mainly medical action in the abdomen. Also, it is thought that an in-depth study on the influence of main ingredients in Bee venom, the wholly honey bee venom aqua upon anti-allergic response or anti-inflammation are further required.

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Development of Passive Millimeter-wave Security Screening System (수동 밀리미터파 보안 검색 시스템 개발)

  • Yoon, Jin-Seob;Jung, Kyung Kwon;Chae, Yeon-Sik
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.7
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    • pp.138-143
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    • 2016
  • The designed and fabricated millimeter-wave security screening system receives radiation energy from an object and a human body. The imaging system consist of sixteen array antennas, sixteen four-stage LNAs, sixteen detectors, an infrared camera, a CCD camera, reflector, and a focusing lens. This system requires high sensitivity and wide bandwidth to detect the input thermal noise. The LNA module of the system has been measured to have 65.8 dB in average linear gain and 82 GHz~102 GHz in bandwidth to enhance the sensitivity for thermal noise, and to receive it over a wide bandwidth. The detector is used for direct current (DC) output translation of millimeter-wave signals with a zero bias Schottky diode. The lens and front-end of the millimeter-wave sensor are important in the system to detect the input thermal noise signal. The frequency range in the receiving sensitivity of the detectors was 350 to 400 mV/mW at 0 dBm (1 mW) input power. The developed W-band imaging system is effective for detecting and identifying concealed objects such as metal or plastic.

Exploring the Problem and Solution in Curriculum Development of School-based Program for the Gifted in the Arts (단위학교 예술영재학급 교육과정 개발의 문제점 및 개선 방안 탐색)

  • Lee, Kyungjin;Kim, Sunghye;Kang, Byoungjik
    • Journal of Gifted/Talented Education
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    • v.25 no.2
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    • pp.299-320
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    • 2015
  • This study aimed to explore the problem in curriculum development in school-based gifted program in the arts and suggest the way to solve that. For this study, we surveyed 28 teachers and guest instructors, furthermore interviewed 6 teachers (4 in music and 2 visual arts). The study results indicated that not only curriculum development of school-based program for the gifted in the arts was not systemic, but also most teacher depended excessively on guest instructors due to the lack of expertise and information for curriculum development. Also, They did not understand specific meaning of the giftedness and gifted curriculum in arts nor recognize the unique role of school-based gifted program. In addition, most teachers simply attempted to solve lack of knowledge and experience on a personal level. Their research condition were inadequate to plan curriculum. To solve these problems in curriculum development in school-based gifted program in arts, we suggested some solutions: differentiated teacher in-service program, the achievement criteria for fundamentals of curriculum, system for connecting materials, information and human resources, as well as consultative body for improving the present condition of school-based gifted program.

Hidden Object Detection System using Parametric Array (파라메트릭 배열을 이용한 은폐 물체 탐지 시스템)

  • Lee, Kibae;Lee, Jaeil;Bae, Jinho;Lee, Chong Hyun;Cho, Jung Hong
    • Journal of the Institute of Electronics and Information Engineers
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    • v.54 no.3
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    • pp.78-86
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    • 2017
  • In this paper, we propose hidden object detection system using parametric array based on acoustic signal that is harmless to human body. A transmit signal of the proposed detection system uses a high directive chirp signal generated from parametric array phenomenon, which uses technique to improve a signal to noise (SNR) of a received signal and a distance resolution trough the dechirp processing. The transmit sensor array is constructed as $8{\times}2$ and has a horizontal beam width of $7^{\circ}$ and vertical beam width of $26^{\circ}$. To verify the detection and visualization of the proposed system, a 2-axis driving control system based on linear stage was constructed, and A-scan, B-scan, and C-scan experiments was addressed for hidden object. From experimental results, we detected and visualized the hidden bronze plate and pipe by cloth and the visualized shapes was confirmed. Especially, the obtained errors was $0.015m^2$ for bronze plate, and $0.046m^2$ for pipe.

Legal Issues on Pharmacopunture (약침의 한방의료행위성에 대한 검토)

  • Jung, Kyu Won
    • The Korean Society of Law and Medicine
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    • v.19 no.1
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    • pp.3-20
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    • 2018
  • Pharmacopunture is a new combined method of acupunture and oriental drugs. Recently, this method is widely used to treat traffic accident patients in oriental medicine. However, there is no evidences of treatment, no information of effects and side-effects of this method, and no information of drugs used. In South Korea, western medicine and oriental medicine are regulated differently. When a new technology is invented in the area of western medicine, that method should pass several stages of clinical trials. After that processes, that method can be done as a medical practice. However, in the area of oriental medicine, there is no process like that. According to in South Korea, medical practice without license are composed of two behaviors. First type is that medical practice is done by a person who has no medical license. Second type is that medical practice is done by a person who has a medical license but the area of the license is different. Because of this reason, the distinction between the western medical practices and the oriental medical practices is very important. Medical practices are protected by license mainly because they can harm human life or body. When we invented new medical practice and try to practice it to the patients, we should consider the risk of that method whether it is western medical practice or oriental medical practice. It is not clear that the pharmcopunture which has been done is satisfied the standard of medical treatment.

A Study on Rehabilitation Treatment Using Radiofrequency Treatment (고주파 통증치료기를 이용한 재활 치료에 대한 연구)

  • Jo, Jae-Hyun;Lee, Sang-Yong;Lee, Geun-Yong;Yoon, Se-Jin;Cheong, Ha-Young;Lee, Sang-Sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.13 no.3
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    • pp.212-218
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    • 2020
  • When Radiofrequency energy is applied to the human body, the vibration width is very short. Therefore, the electrolyte burn generated when using the direct current does not occur. Ion molecules, polarized molecules, etc., vibrate more than 40,000 times per second, converting them into frictional heat to generate deep heat. The blood flow of capillaries increases 4-5 times more than at rest, increasing the supply of oxygen, nutrients, antibodies, and white blood cells. In addition, the electrochemical reaction does not occur because the vibration width and the pulsation period are very short. It is a physical factor treatment method that does not stimulate the sensory nerves and motor nerves. In this study, an isotonic exercise is performed in a young normal adult using a Radiofrequency pain treatment device. The purpose of this study is to integrate rehabilitation therapy by measuring electromyography data during isotonic exercise and confirming the effect on changes in motor neuron response. The EMG data generated when isotonic exercise of the forearm biceps muscle and the EMG data measured after the use of a Radiofrequency pain treatment device after exercise were RMS, respectively, and verified through t-test. It was confirmed that there was a significant difference in both men and women because the t-value was smaller than the significance level p (<.05).

Development of Livestock Traceability System Based on Implantable RFID Sensor Tag with MFAN (MFAN/RFID 생체 삽입형 센서 태그 기반 가축 이력 관리 시스템 개발)

  • Won, Yun-Jae;Kim, Young-Han;Lim, Yongseok;Moon, Yeon-Kug;Lim, Seung-Ok
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37C no.12
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    • pp.1318-1327
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    • 2012
  • With the recent increased risk of livestock disease spread and human infection, livestock disease control has become very important. Consequently, there has been an increased attention on an implantable real-time monitoring and traceability system for individual cattle. Therefore, we have developed a robust monitoring and traceability system based on an implantable MFAN/RFID sensor tag. Our design combines the MFAN technology that is capable of robust wireless communication within cattle sheds and the 900MHz RFID technology that is capable of wireless communication without battery. In MFAN/RFID implantable sensor tag monitoring system, UHF sensor tag is implanted under the skin and accurately monitors the body temperature and biological changes without being affected by external environment. In order to acquire power needed by the tag, we install a MFAN/RFID tranceiver on the neck of cattle. The MFAN coordinator passes through the MFAN node and the RFID-reader-combined MFAN/RFID transceiver and transmits/receives the data and power for the sensor tag. The data stored in the MFAN coordinator is transmitted via the internet to the livestock history monitoring system, where it is stored and managed. By developing this system, we hope to alleviate the problems related to livestock disease control.

Localizing Head and Shoulder Line Using Statistical Learning (통계학적 학습을 이용한 머리와 어깨선의 위치 찾기)

  • Kwon, Mu-Sik
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.2C
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    • pp.141-149
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    • 2007
  • Associating the shoulder line with head location of the human body is useful in verifying, localizing and tracking persons in an image. Since the head line and the shoulder line, what we call ${\Omega}$-shape, move together in a consistent way within a limited range of deformation, we can build a statistical shape model using Active Shape Model (ASM). However, when the conventional ASM is applied to ${\Omega}$-shape fitting, it is very sensitive to background edges and clutter because it relies only on the local edge or gradient. Even though appearance is a good alternative feature for matching the target object to image, it is difficult to learn the appearance of the ${\Omega}$-shape because of the significant difference between people's skin, hair and clothes, and because appearance does not remain the same throughout the entire video. Therefore, instead of teaming appearance or updating appearance as it changes, we model the discriminative appearance where each pixel is classified into head, torso and background classes, and update the classifier to obtain the appropriate discriminative appearance in the current frame. Accordingly, we make use of two features in fitting ${\Omega}$-shape, edge gradient which is used for localization, and discriminative appearance which contributes to stability of the tracker. The simulation results show that the proposed method is very robust to pose change, occlusion, and illumination change in tracking the head and shoulder line of people. Another advantage is that the proposed method operates in real time.

Experimental Research for Traction force Sensor Development on Drawing Exercise Medical Instrument (재활 및 교정을 위한 견인운동치료기의 견인측정센서 개발에 관한 실험적 연구)

  • Lee, Sang-sik;Park, Won-yeop;Lee, Choong-ho
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.2 no.2
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    • pp.3-8
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    • 2009
  • The traction system has been mainly used for rehabilitation and correction of patients with spine or gait diseases in orthopedics or at home. Some problems could occur in human body when patients forced their training using the traction system. So it needs to measure a traction force and control the training time. However, most of products on market have no sensor measuring traction force. Thus we designed and made a sensor detecting traction force using strain gauge, amplifier for transition to output signal and experiment devices for performance test. We carried out experiment of a sensor detecting a traction force and measured electric responses of it with respect to traction loads. Maximum error was within about 1% for experiments in static condition and the average error was about 0.7% for experiments in dynamic condition. We concluded that it is possible to use the developed sensor for measurement of traction force since the maximum output variation of a sensor detecting a traction force was about 0.3% in $0^{\circ}C-60^{\circ}C$ temperature condition.

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A New Locomotor Evaluation System for Mouses Based on Continuous Shooting Images (연속 촬영 이미지를 이용한 Mouse의 운동 능력 평가 시스템)

  • Kwak, Ho-Young;Huh, Jisoon;Lee, Won Joo
    • Journal of the Korea Society of Computer and Information
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    • v.20 no.1
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    • pp.153-161
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    • 2015
  • In this paper, we propose a locomotor evaluation System for mouse based on continuous shooting images. In the field of veterinary medicine and animal studies are subjected to using the mouse for the quality of human life. In particular, during the experiments using the artificially created mice injury, through a variety of scoring and a lot of experiments to measure the extent of recovery from the injury. The traditional method of measuring the quantity of exercise while in this experiment was made of a method for directly observing person. The proposed system performs the continuous shooting per unit of time specified by the movement of the mouse is extracted from a continuous image shooting with the outline of a mouse point cloud. And using the extracted point cloud to extract again the inner contour of the body of the mouse. So using the new point cloud obtained its center, Then, using the center point calculated by accumulating the distance between two points on locomotor evaluation system design and implement to obtain the total distance the mouse moves over a unit of time.