• 대한기계학회논문집A
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• 제20권9호
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• pp.2800-2811
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• 1996

The deformation of a structure shall be called homologous, if a given geometrical relation holds, for a given number of structural points, before, during, and after the deformation. Some researchers have utilized the idea on structural design with finite element method. The approaches use the decomposition of the FEM equation or equality of eqality equations to obtain homologous deformation. However, weight reduction and response constraints such as stress, displacement or natural frequency cannot be considered by those theories. An optimization method solving the above problems is suggested to gain homologous deformation. Homology constraints can be considered under multiple loadindg conditions as well as a single loading condition. Homology index is defined for the multiple loading conditions Examples are solved to present the performances of the method.

• 대한수학회지
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• 제36권5호
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• pp.911-921
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• 1999

We define the coincidence index of pairs of maps p, f : $\widetilde{X}$ $\rightarrow$ X where p is a covering of a polyhedron X. We use a polyhedral transversality Theorem due to T. Plavchak. When p=identity we get the classical fixed point index of self map of polyhedra without using homology.

• Journal of Animal Science and Technology
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• 제57권12호
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• pp.44.1-44.9
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• 2015

Background: Heat shock proteins play an important role in protection from stress stimuli and metabolic insults in almost all organisms. Methods: In this study, computational tools were used to deeply analyse the physicochemical characteristics and, using homology modelling, reliably predict the tertiary structure of the blunt snout bream (Ma-) Hsp70 and Hsc70 proteins. Derived three-dimensional models were then used to predict the function of the proteins. Results: Previously published predictions regarding the protein length, molecular weight, theoretical isoelectric point and total number of positive and negative residues were corroborated. Among the new findings are: the extinction coefficient (33725/33350 and 35090/34840 - Ma-Hsp70/ Ma-Hsc70, respectively), instability index (33.68/35.56 - both stable), aliphatic index (83.44/80.23 - both very stable), half-life estimates (both relatively stable), grand average of hydropathicity (-0.431/-0.473 - both hydrophilic) and amino acid composition (alanine-lysine-glycine/glycine-lysine-aspartic acid were the most abundant, no disulphide bonds, the N-terminal of both proteins was methionine). Homology modelling was performed by SWISS-MODEL program and the proposed model was evaluated as highly reliable based on PROCHECK's Ramachandran plot, ERRAT, PROVE, Verify 3D, ProQ and ProSA analyses. Conclusions: The research revealed a high structural similarity to Hsp70 and Hsc70 proteins from several taxonomically distant animal species, corroborating a remarkably high level of evolutionary conservation among the members of this protein family. Functional annotation based on structural similarity provides a reliable additional indirect evidence for a high level of functional conservation of these two genes/proteins in blunt snout bream, but it is not sensitive enough to functionally distinguish the two isoforms.

• Kyungpook Mathematical Journal
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• 제55권1호
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• pp.169-180
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• 2015

We study the braid indices of the Kanenobu knots. It is known that the Kanenobu knots have the same HOMFLYPT polynomial and the same Khovanov-Rozansky homology. The MFW inequality is known for giving a lower bound of the braid index of a link by applying the HOMFLYPT polynomial. Therefore, it is not easy to determine the braid indices of the Kanenobu knots. In our previous paper, we gave upper bounds and sharper lower bounds of the braid indices of the Kanenobu knots by applying the 2-cable version of the zeroth coefficient HOMFLYPT polynomial. In this paper, we give sharper upper bounds of the braid indices of the Kanenobu knots.

• 대한수학회지
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• 제54권5호
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• pp.1411-1440
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• 2017

We study free actions of finite groups on 3-dimensional nil-manifolds with the first homology ${\mathbb{Z}}^2{\oplus}{\mathbb{Z}}_p$. By the works of Bieberbach and Waldhausen, this classification problem is reduced to classifying all normal nilpotent subgroups of almost Bieberbach groups of finite index, up to affine conjugacy.

• 한국정보과학회논문지:데이타베이스
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• 제33권3호
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• pp.251-260
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• 2006

단백질 일차 구조(아미노산 배열)에 대한 상동 검색은 유전자나 단백질의 기능과 진화 과정을 유추하기 위한 필수 연산이다. 그러나 진화 단계가 멀리 떨어진 경우 단백질 일차 구조는 보존되지 않기 때문에 단백질의 공간적 구조에 대한 유사 검색을 통해서만 진화 단계를 유추할 수 있다. 따라서 본 논문에서는 단백질의 공간적 구조를 표현하는 단백질 이차 구조를 대상으로 하여 RDBMS상에 쉽게 구현이 가능한 인덱싱 방안을 제안한다. 제안된 인덱싱 방안은 클러스터링 기법과 LookAhead 개념을 활용하여 Exact Match, Range Match, Wildcard Match 질의를 신속하게 처리한다. 제안된 방법의 우수성을 검증하기 위하여 실제의 단백질 데이타를 대상으로 성능 평가를 수행하였다. 실험 결과에 의하면, 제안된 방법은 기존의 방법과 비교하여 Exact Match의 경우 6.3배까지, Range Match의 경우 3.3배까지, Wildcard Match의 경우 1.5배까지의 개선된 검색 성능을 가지는 것으로 나타났다.

• 농업생명과학연구
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• 제46권4호
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• pp.9-20
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• 2012

Eugenol은 많은 식물에서 eugenol synthase에 의해 생합성되는 phenylpropene 계통의 휘발성 화합물이다. 그러나, 토마토 과실에서의 특징은 밝혀져 있지 않다. 이에 따라 토마토 'Micro-Tom'으로부터 RACE 기법을 이용하여 완전장 cDNA를 클로닝 하여, SlEGS라 명명하였다. SlEGS의 open reading frame은 921bp로, 307개의 아미노산 서열을 갖는 단백질로 번역되었다. BLAST 결과에 따라 SlEGS는 PhEGS1 및 CbEGS2와 각 67.1, 69.4%의 높은 상동성을 갖는 것으로 나타났다. CLC genomics workbench 프로그램을 이용하여 SlEGS의 아미노산 구성을 분석하였고, Swiss-PDB viewer 프로그램에서 homology modeling 기법으로 SlEGS의 3차원 단백질 구조를 구축한 후 ProSA-web 툴로 3차원 구조의 안정성을 확인 하였다. 또한 ExPASy의 ProtParam 툴을 이용하여 SlEGS의 생리화학적 특성을 분석 하였다. SlEGS의 추정 분자량은 33.93kDA이고 등전점(pI)은 5.85로 산성인 것으로 나타났다. 이와 더불어 SlEGS의 흡광 계수(EC), 불안정성 지수(II), alipathic 지수(AI), GRAVY값 등의 생리화학적 특성에 대한 분석을 실시 하였다.

• Journal of Plant Biotechnology
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• 제5권4호
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• pp.201-207
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• 2003

Tissue culture techniques arguably are an important approach for ex situ conservation of rare and endangered plant species. However, there is utmost importance on maintaining the genetic integrity of the introduced plants especially in tree species. To examine the genetic integrity of the micropropagated plants, we randomly screened few hardened plants of Syzygium travancoricum, a critically endangered tree taxon, using Randomly Amplified Polymorphic DNA (RAPD) markers. Twenty-three random. primers were tried and twenty-five polymorphic loci were identified. The dendrogram based on the Unweighted Pair-Group Method Arithmetic Average and Nei's similarity index depicted about 97% homology between the mother plants and micropropagated plants. Further, an attempt was made to reintroduce the micropropagated plants in the wild. Over three hundred small trees could be successfully established.

• 한국치위생학회지
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• 제19권3호
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• pp.375-385
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• 2019

Objectives: The purpose of this study was to provide basic data for gingivitis management programs by dental hygienists by evaluating the effect of oral health education, oil pulling, and professional toothbrushing on gingivitis. Methods: A total of 38 subjects were divided into three groups: control group (12 subjects), experimental group 1 (13 subjects), and experimental group 2 (13 subjects). The control and experimental groups were instructed to brush using the rotating method. Distilled water was provided to the control group after training. Coconut oil was provided every morning for about 10 minutes. In the experimental group 2, a professional brushing method was used at each visit. Results: There were no significant differences in oral health among the three groups, and there was homology between patient hygiene performance (PHP) index (p=0.144) and bleeding rate (p=0.213). The PHP index showed a significant interaction between the group and measurement time. The control and experimental groups showed changes in the PHP index with time (F=3.711; p=0.013). The bleeding rate showed a significant interaction between the group and measurement period. The control and experimental groups showed changes in the bleeding rate with time (F=6.707; p<0.001). Conclusions: Oral health education, professional toothbrushing, and oil pulling specialists in oral care of gingivitis were effective in managing gingivitis. It is necessary to educate people on self-management methods for oral health promotion using gingivitis management programs by dental hygienists.

• Molecules and Cells
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• 제24권3호
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• pp.437-440
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• 2007

$OGL-20P^T$-358 is a novel 66 amino acid residue protein from the hyperthermophile Thermococcus thioreducens sp. nov., strain $OGL-20P^T$, which was collected from the wall of the hydrothermal black smoker in the Rainbow Vent along the mid-Atlantic ridge. This protein, which has no detectable sequence homology with proteins or domains of known function, has a calculated pI of 4.76 and a molecular mass of 8.2 kDa. We report here the backbone $^1H$, $^{15}N$, and $^{13}C$ resonance assignments of $OGL-20P^T$-358. Assignments are 97.5% (316/324) complete. Chemical shift index was used to determine the secondary structure of the protein, which appears to consist of primarily ${\alpha}$-helical regions. This work is the foundation for future studies to determine the three-dimensional solution structure of the protein.