• YAKHAK HOEJI
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• v.43 no.2
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• pp.150-159
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• 1999

Hollow type suppositories inserted polyvinyl alcohol (PVA) hydrogel capsule containing propranolol·HCI (PPH) were prepared using different bases, polyethylene glycol (PEG), Witepsol H-15 (WH-15) and Witepsol W-35 (WW-35) to improve the controlled release of PPH. The release of PPH from the hollow type suppository inserted PVA hydrogel capsule was retarded than that from PEG, WH-15, or WW-35 hollow type suppositories in rat rectal cavity. When the suppositories were administered to rats, the controlled release of PPH was proved by the plasma concentration-time-profiles of PPH. No significant difference (p〈0.05) among the three different hollow type suppositories was observed in terms of AUC and MRT of PPH. WH-15 hollow type suppository inserted 12% of PVA hydrogel capsule caused irritation to rat rectal mucosa. However, the WH-15 hollow type suppository inserted PVA hydrogel capsule caused no severe irritation on rectal mucosa. The application of the hollow type suppositories using PVA in sustained rectal delivery of drugs might be feasible.

• YAKHAK HOEJI
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• v.35 no.3
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• pp.197-202
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• 1991

In order to study drug release from the suppository, three types of hollow suppositories and one conventional suppository were prepared using indomethacin(IDM) as a model drug and Witepsol H-15 as a base. The 4 types of suppository prepared are as follows: type I, conventional suppository containing 50 mg of IDM powder, type II, hollow supository containing 50 mg of IDM powder in the cavity, type III, hollow suppository containing 25 mg of IDM powder in the base and IDM microcapsules (25 mg as IDM powder) in the cavity, and type IV, hollow suppository containing IDM microcapsules (25 mg as IDM powder) in the base and 0.5 ml of 5%(w/v) IDM-PEG 300 solution in the cavity. The drug amount released(%) from type II and I within 24 hrs was 46.7% and 66.9%, respectively. Comparing with the drug amount released from four types of suppository within initial 2 hrs and 24 hrs, that of type IV was high as 32.7% and 76.6%, respectively. IDM-ethycellulose microcapsules passed through 270 mesh sieve and the IDM content was 20.95%.

• Proceedings of the Korea Concrete Institute Conference
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• 2010.05a
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• pp.31-32
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• 2010

This paper presents the flexural capacities of one-way hollow slab with donut type hollow sphere. According to analytical studies, the hollow slab with donut type hollow sphere had good flexural capacities such as strength, stiffness and deflection. To verify the flexural capacities of this hollow slab, flexural tests were performed on the one-way hollow slabs.

• Korean Journal of Clinical Pharmacy
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• v.8 no.2
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• pp.143-146
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• 1998

Acetaminophen (APAP) suppositories with active ingredients, i.e., polyethylene glycol (PEG), Witepsol H-15 (WH), were prepared for hospital use and investigated on their drug release characteristics and pharmacokinetics. WH was employed as oil-soluble base with an aim of reducing fragility and mucosa irritancy that are common drawbacks found in PEG suppositories. Also hollow type suppository was tried as compared with conventional type suppository. Drug release tests revealed that in most formulations, more than $80\%$ of loaded APAP were released within 20 minutes, except for APAP-WH hollow type suppositories. Significant differences in the plasma concentration profile were observed among four type suppositories. $T_{max}$ of APAP-PEG and APAP-WH suppositories were 90 and 60 minutes, respectively, in hollow types. APAP-WH hollow type suppositories demonstrated fast absorption rates of APAP as compared with those of APAP-PEG suppositories. No burst effect was observed from APAP-WH suppository in contrast to APAP conventional type suppository, whereas AUCs of all the suppositories were similar. APAP-WH hollow type suppository may be an useful dosage form for hospital use.

• Proceedings of the Korean Nuclear Society Conference
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• 1998.05b
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• pp.427-432
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• 1998

중수속의 삼중수소 제거 공정인 액상 촉매 교환 반응에서 중수의 촉매 표면 응축에 의한 성능 저하가 큰 문제의 하나로서 성능 저하를 감소시키기 위한 여러 가지 형태의 촉매탑이 고안 되었다. 본 연구에서는 membrane을 사용하여 중수와 촉매를 분리시킴으로써 촉매 성능 저하를 감소시킬 수 있는 촉매탑의 설계를 시도하였다. 세 가지 촉매탑이 고안되었는데 sheet type의 membrane을 사용한 multilayered type 과 double spiral type, hollow fiber membrane을 사용한 hollow fiber cartridge type 등이다. multilayered type은 구조가 단순하여 scale-up이 용이하고 double spiral type은 다른 type보다 유로의 blocking 문제가 작고 hollow fiber cartridge type은 최대의 비표면적을 가질 수 있다.

• Journal of the Korea Concrete Institute
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• v.25 no.2
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• pp.155-163
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• 2013

This study investigated the bond characteristics of embedded deformed steel bar in donut type biaxial hollow slabs. The donut type hollow sphere make concrete inner cover formed between steel bar and hollow sphere due to the hollow shape and arrangement. Generally, inner cover was thinner than outer cover, and some part of donut type biaxial hollow slab has smaller inner cover thickness than $2.5d_b$. It was affected to the bond condition of deformed bar. Furthermore, inner cover thickness changes along the longitudinal deformed bar due to hollow shape. Therefore, donut type hollow slab was divided 3 regions according to the hollow shape such as insufficient region, transition region, sufficient region. Pull-out test were performed to find out the effect of bond condition by the region. Main parameters are inner cover thickness, embedded length and bond location. Bond characteristics of donut type biaxial hollow slab were confirmed through comparison of bond stress-slip relationship, maximum bond strength and bond stress distribution of each regions. And the calculation method of bond strength of donut type biaxial hollow slab was suggested based on the test results.

• Journal of Environmental Health Sciences
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• v.27 no.3
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• pp.27-34
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• 2001

This paper discussed the shape effect of ceramic support carrier in order to facilitate biomass immobilization. The shape of ceramic support carrier was modified hollow pipe type into hollow gear type. After seeding, microorganisms were attached in crevices where protection from shear forces or surfaces where easy to contact with support carrier surface. In case of hollow gear type carrier, initial attachment rate was faster than that of hollow pipe type and obtained thick biofilm. Synthetic wastewater(COD:75~880 mg/L, organic loading rate:0.36~4.22 kgCOD/㎥.d) was treated aerobic fixed bed biofilm reactor where 100% of the volume was filled with the ceramic carrier. COD removal efficiency of reactor filled with gear type support carrier was a little high withing 70 days, and then showed similar removal efficiency. It was found that highly loaded operation with up to 4.22 kgCOD/㎥.d was possible in both reactor. Total biomass amounts of pipe type was higher than gear type, however, attached biomass of gear type was higher than that of pipe type.

• Journal of Chest Surgery
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• v.25 no.5
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• pp.451-457
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• 1992

The hollow fiber oxygenator is the most advanced one for the cardiopulmoanry bypass. They have two different types of the hollow fiber systems according to the way how the blood go through the fibers. One is inside blood flow type and the other outside type. In order to find out which is better to prevent blood cell destruction, we selected 40 valve replacing patients and divided them into 2 groups prospectively. In group I [n=20], inside blood flow type[BCM-7a], CO2 excretion is more effective than group II, that is partly because of the relative large surface area of the BCM-7. In group II [n=20], outside blood flow type [MAXIMAa], they have better quality to preserve platelet count. We also studied about several other items such as SaO2, Hemoglobin and RBC, WBC, fibrinogen, LDH, plasma hemoglobin, haptoglobulin and so on. But we cannot find any differences between two groups with any statistical meanings [p<0.05]. We conclude that both of two oxygenators are excellent in the aspects of gas exchange and blood cell preservation.

• Journal of the Korean Institute of Gas
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• v.20 no.3
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• pp.73-77
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• 2016

This paper presents the displacement behavior safety of hollow shafts with an equivalent volume for various cross sectional area using a finite element method. The FEM results indicate that the hollow shafts with X-type or Y-type columns between outer tube, middle tube and inner tube may reduce a maximum displacement at the middle length of hollow shafts. Especially, the load-bearing column of X-type or Y-type hollow shaft is directly connected between outer tube and inner tube without a shift for reducing the vertical displacement. And increased thickness of a load-bearing column is recommended for reducing the vertical displacement and increasing the displacement behavior safety for an equivalent volume of a hollow shaft.

• Journal of the Semiconductor & Display Technology
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• v.11 no.2
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• pp.23-26
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• 2012

The monodispersed polystyrene spheres were prepared by emulsion polymerization in aqueous alcohol system. They coated with silver by reduction of silver ion percolated on the surface of them. The spherical hollow type silver has been prepared by dissolving polystyrene with toluene. Epoxy resin compositions with spherical hollow type silver were manufactured, which were composed of a bisphenol F type epoxy resin (RE-304S), amine type hardener (Kayahard AA), and 1-benzyl 2-methyl imidazole (1B2MI) as catalyst. The electrical conductivity with silver content ratio were investigated after cure, the percolation threshold weight ratio for conductance in this epoxy resin system was obtained above the 70 wt% of silver.