• The Journal of Sustainable Design and Educational Environment Research
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• v.13 no.3
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• pp.15-22
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• 2014

Proceeded with a research with basic data about the qualification standard improvement scheme about the environment school architecture in which a comparison analyze the specialized field of BREEAM system of LEED of the hit environment building qualification standard G-SEED of the domestic and U.S Green Building Counci evaluated with the certification system of the world top class and Building Research Establish, essential item, and mark distribution and weight in this study at this and which I hit with a domestic afterward. The school facility with a hub among the equipment receiving the hit environmental qualification standard, and the range of this research does LEED of the domestic green building certification system February is revised in 2013 G-SEED and which US and BREEAM in UK with a range. The way of the research checked the environment school building certification system and situation hit home and abroad, and a comparison analyze the division of the specialized field of each country qualification standard, essential item, and mark distribution and weight.

• Journal of Communications and Networks
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• v.8 no.3
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• pp.330-338
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• 2006

Many web cache systems and policies concerning them have been proposed. These studies, however, consider large objects less useful than small objects in terms of performance, and evict them as soon as possible. Even if this approach increases the hit rate, the byte hit rate decreases and the connections occurring over congested links to outside networks waste more bandwidth in obtaining large objects. This paper puts forth a client-cluster approach for improving the web cache system. The client-cluster is composed of the residual resources of clients and utilizes them as exclusive storage for large objects. This proposed system achieves not only a high hit rate but also a high byte hit rate, while reducing outgoing traffic. The distributed hash table (DHT) based peer-to-peer lookup protocol is utilized to manage the client-cluster. With the natural characteristics of this protocol, the proposed system with the client-cluster is self-organizing, fault-tolerant, well-balanced, and scalable. Additionally, the large objects are managed with an index based allocation method, which balances the loads of all clients well. The performance of the cache system is examined via a trace driven simulation and an effective enhancement of the proxy cache performance is demonstrated.

• Journal of the Society of Naval Architects of Korea
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• v.59 no.6
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• pp.413-422
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• 2022

Blast Hardened Bulkheads (BHB) are used to suppress damage propagation by internal explosions to reduce ships'vulnerability. However, for this reason, the weight of the ship inevitably increased, and other functions such as the ships'mobility were bound to deteriorate. Therefore, it is essential in the initial design of the ship to optimize the dimensions of the bulkhead to minimize the weight while decreasing the vulnerability of the ship. Research on design optimization of BHB has been conducted, but it has not considered explosive load in various hit scenarios. This study proposed an optimal design method for the curtain plate type blast hardened bulkhead, which is currently frequently applied by the Korean Navy in consideration of various hit scenarios. Using genetic algorithms, multiobjective design optimizations that minimize weight increase as well as minimize damage to ships were obtained. By optimizing the dimensions of the BHB considering various hit scenarios, the ship's vulnerability was improved while maintaining its mobility due to weight reduction.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.5
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• pp.1040-1048
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• 2016

Recently, the studies of integrated reliability analysis for combat systems are actively progressing. Especially, the research of integrated reliability analysis is emphasized to overcome limitations of the previous studies. In this paper, we propose a calculation technique for integrated hit probability based on front and side hit probabilities that analyzed in previous studies to improve the time-effectiveness. Also, we find out the integrated reliability of each component based on the integrated hit probability which is calculated, and we propose the method which applied the reliability block diagram technique to analyze the whole combat system of the reliability by function kills. For verifying the proposed method, we applied the proposed method to armored fighting vehicle model. The proposed method considers crew which does not considered the element in the previous study and expects to enhance the accuracy of reliability analysis and the time-effectiveness compared with the previous study.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.3
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• pp.211-216
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• 2014

Endoplasmic reticulum (ER) stress, unfolded protein response (UPR), and mitochondrial biogenesis were assessed following varying intensities of exercise training. The animals were randomly assigned to receive either low- (LIT, n=7) or high intensity training (HIT, n=7), or were assigned to a control group (n=7). Over 5 weeks, the animals in the LIT were exercised on a treadmill with a $10^{\circ}$ incline for 60 min at a speed of 20 m/min group, and in the HIT group at a speed of 34 m/min for 5 days a week. No statistically significant differences were found in the body weight, plasma triglyceride, and total cholesterol levels across the three groups, but fasting glucose and insulin levels were significantly lower in the exercise-trained groups. Additionally, no statistically significant differences were observed in the levels of PERK phosphorylation in skeletal muscles between the three groups. However, compared to the control and LIT groups, the level of BiP was lower in the HIT group. Compared to the control group, the levels of ATF4 in skeletal muscles and CHOP were significantly lower in the HIT group. The HIT group also showed increased PGC-$1{\alpha}$ mRNA expression in comparison with the control group. Furthermore, both of the trained groups showed higher levels of mitochondrial UCP3 than the control group. In summary, we found that a 5-week high-intensity exercise training routine resulted in increased mitochondrial biogenesis and decreased ER stress and apoptotic signaling in the skeletal muscle tissue of rats.

• Journal of Korean Physical Therapy Science
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• v.21 no.1
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• pp.65-77
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• 2014

Purpose : This research is to understand the academic self-efficacy of trainees receiving the 4 category-union education of HIT(Health Integrated Technic) Methods : A self-administered questionnaire survey was conducted in 450 health-related college students in Daegu city from April to July. A statistical analysis was performed using SPSS 17.0 for window version. Results : First, satisfaction to education of HIT was higher in vocational consciousness program than patient care programme educational deepening program. Second, academic self-efficacy to education of HIT was higher in educational deepening program than patient care programme vocational consciousness program. Conclusion : Systemic education is needed to develop vocational consciousness, patient care and educational deepening that suit the characteristics of college students in order to establish an environment for revitalizing satisfaction and academic self-efficacy to 4 category-union education

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.1
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• pp.31-35
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• 2010

This study was designed to evaluate anti-diabetes effect of Helianthus tuberosus extract (HT) in HIT-T15 cells. There were 5 experimental groups according to treatment NC (0 ${\muL/mL$), HT2 (1.1 ${\muL/mL$), HT3 (1.5 ${\muL/mL$), IN2 (1.8 ${\muL/mL$), IN3 (2.5 ${\muL/mL$). Inulin (IN) was used as a positive control for the Helianthus tuberosus extract groups. Cell viability was significantly increased in the HT3 (1.5 ${\muL/mL$), IN2 (1.8 ${\muL/mL$), IN3 (2.5 ${\muL/mL$) groups, compared with the NC group. There was no significant difference in cytotoxicity among all groups. Cell survival by MTT assay with alloxan was significantly increased in the HT2 (1.1 ${\muL/mL$), HT3 (1.5 ${\muL/mL$) groups, compared with the NC group. Insulin secretion and NAD+/NADH ratio were significantly increased in the HT3 group, compared with the NC group. We found that Helianthus tuberosus extract increased cell viability, had a protective effect on $\beta$-cells, and increased insulin secretion level and $NAD^+$/NADH ratio in HIT-T15 cells. These results suggest that Helianthus tuberosus extract improves the diabetes-related factors.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.4B
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• pp.783-787
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• 2000

A microprocessor, which is used as a CPU for state-of-the-art personal computers, adopts 256KB or 512KB L2(Level 2) cache memory. This cache hires Direct Mapping Procedure, 32B Line Size, and no Write Allocation. In this cache architecture, we can expert about 2.5% hit ratio improvement by using 8-way Set Associative Mapping instead of Direct Mapping, 128B Line Size instead of 32B, and Write Allocation.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.35 no.6
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• pp.408-411
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• 2013

After radical excision of a tumor in the maxillofacial area, functional and esthetic reconstruction is needed, including flap surgery. Among the many etiologies of flap failure, venous thrombosis is one of the most frequent. Heparin is used routinely in the effort to avoid development of venous thrombosis. In rare cases, heparin-induced thrombocytopenia (HIT) type II occurs due to exposure to heparin. Heparin attached to platelet factor 4 forms a PF4/heparin-immunoglobulin G immune complex on platelet surfaces. This complex activates platelets, which leads to multiple coagulation in venous and arterial blood. We report here on a rare occurrence of HIT type II following fibula free flap surgery.

• Biomedical Science Letters
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• v.15 no.2
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• pp.105-112
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• 2009

The screening of the anti-cancer activity of the chemical library provided 2-thio-4-aminopyrimidine as the initial hit. The confirmation of structure and biological effect of hit was performed by synthesis and biological evaluation. The optimization of hit was performed by derivatization of substituents while keeping the core structure. The evaluation of growth inhibitory activity was carried out using SRB assay against 6 human cancer cell lines and human fibroblast. The growth inhibitory activity of compounds showed substituent dependency and more than 5 compounds showed complete growth inhibition of cancer cell lines at 10 ${\mu}M$ concentration. Chemical library screening followed by synthetic modification provided possibility that 2-thio-4-aminopyrimidine can be used as a new scaffold for the development of anti-cancer agent.