• Journal of Veterinary Clinics
• /
• v.20 no.2
• /
• pp.259-262
• /
• 2003

A 13-year old male dog with right forelimb lameness, invisible swelling, anorexia and mild depression was referred to Veterinary leaching Hospital, College of Veterinary Medicine, Kyungpook National University. On forelimb radiographic views, periosteal and endosteal proliferation and cortical lysis and extremely aggressive and amorphous periosteal reactions were located along the metaphyseal region of the proximal humerus. Cytologic and histopathologic examinations after amputation showed anaplastic mesenchymal cells that produced osteoid changes, poorly differentiated osteoblast and osteoclast. And also, it included the neoplastic cells with large nucleoli, multiple nucleoli that differ in size and cytoplasm with several clear vacuoles. Based on the physical examination and laboratory, radiolographic, cytologic and histopathologic findings, this case was diagnosed as osteosarcoma of the proximal humerus.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.23 no.1
• /
• pp.15-20
• /
• 2001

For the earlier diagnosis and treatment of delayed wound healing in extraction socket, we investigated the clinical, radiographic and histopathologic features of 106 patients with delayed wound healing diagnosed by biopsy. The patients were enrolled at the Department of Oral Pathology, Chosun University Dental Hospital. Among 106 delayed wound healing diagnosed by biopsy, cysts showed most significant 25 cases (23%), osteomyelitis showed 13 cases (12%), chronic maxillary sinusitis and squamous cell carcinoma showed 12 (11%) and 11 (10%) cases, respectively. We have analyzed these lesions through relevant literatures.

• The Journal of the Korean dental association
• /
• v.58 no.5
• /
• pp.293-303
• /
• 2020

Biopsy is a critical method for disease diagnosis and treatment planning. It can be applied from simple inflammatory lesions to malignant tumors. But many general dental practitioners are unfamiliar with the basic knowledge and skills required for biopsy. Moreover, biopsy indications and contraindications for certain diseases may differ depending on the type of dental practice environment and the specialty of the dentist. Biopsy education can increase the choices a dentist has during disease diagnosis. Here we will discuss details on biopsy needed to the general dentist.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.19 no.3 s.31
• /
• pp.60-67
• /
• 2006

Objective : Allergic rhinitis is an allergic reaction characterized by sneezing, coughing, itchy nose, mouth and throat, congestion and/or nasal discharge. We aim to observe effect of Sinichengpae-um on protective effects of nasal mucosal tissue in th allergic rhinitis. Method : For this purpose, we oberserved number of leukocyte and erythrocyte in blood, ratio of neutrophil and lymphocyte in leukocyte, activity of GOT and GPT, and histopathologic change of nasal mucose. Result and Conclusion : Sinicheogpae-um showed effects on immune reaction with no harms liver. And in histopathologic change of nasal mucosal tissue, Sinichengpae-um showed significant protective effet against allergic rhinitis.

• Biomolecules & Therapeutics
• /
• v.3 no.3
• /
• pp.229-232
• /
• 1995

In order to study if Glycyrrhizae Radix (GR) has protective effects on hepatotoxicity of acetaminophen in mouse, one of the species which are sensitive to acetaminophen-induced hepatotoxicity, effects of GR on liver weight to body weight ratio, serum alanine and aspartate transaminase (ALT and AST) activities, hepatic UDP-GT2 activity, and histopathologic changes were determined in acetaminophen-treated mice. Liver weight to body weight ratio and UDP-GT2 activity in mouse liver were not altered by GR. However, GR pretreatment lowered serum ALT and AST activities by 77% and 90% respectively, and diminished the degree of centrilobular necrosis caused by acetaminophen in liver as determined by histopathologic observation. These results suggest a possible protective effect of GR against the acetaminophen-induced hepatotoxicity in mice.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.41 no.1
• /
• pp.37-42
• /
• 2015

Aggressive benign odontogenic neoplasms have substantial potential to grow to an enormous size with resulting bone deformities, and they often invade adjacent tissues and spread beyond their normal clinical and radiographic margins; as such, they have a high rate of recurrence. Historically, management (conservative versus aggressive) on the basis of clinical, radiographic and/or histopathologic characteristics has been controversial. However, recent advances in the understanding of the biological features of these lesions may provide greater evidence of the benefits of conservative management. Three patients with different complaints and final histopathologic diagnoses were enrolled in the study. All three cases were treated by a single operator with similar conservative surgical procedures. During follow-up, the patients had uneventful secondary healing and bone regeneration, less packing time than previously reported, no clinical or radiographic evidence of recurrence and no apparent deformity. The aggressive behavior of these lesions requires long clinical and radiographic follow-up. Conservative surgical management may be an option to reduce recurrence and morbidity and increase the probability of uneventful secondary healing and bone regeneration.

• Investigative Magnetic Resonance Imaging
• /
• v.20 no.2
• /
• pp.136-139
• /
• 2016

Clear cell sarcoma is rare and difficult to diagnose. Herein, we present a case of clear cell sarcoma in the dorsum of the wrist with MRI findings, including diffusion-weighted imaging, and histopathologic correlation, which was initially diagnosed as giant cell tumor of tendon sheath.

• The Journal of the Korean dental association
• /
• v.19 no.9 s.148
• /
• pp.789-804
• /
• 1981

• The Journal of the Korean dental association
• /
• v.21 no.9 s.172
• /
• pp.741-753
• /
• 1983

• The Journal of the Korean dental association
• /
• v.13 no.4
• /
• pp.319-328
• /
• 1975