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Osteosarcoma of the Proximal Humerus in a Dog  

김정은 (경북대학교 수의과대학)
엄기동 (경북대학교 수의과대학)
배재성 (경북대학교 수의과대학)
강한샘 (경북대학교 수의과대학)
이문학 (경북대학교 수의과대학)
이해운 (경북대학교 수의과대학)
성윤상 (경북대학교 수의과대학)
이정민 (경북대학교 수의과대학)
장광호 (경북대학교 수의과대학)
Publication Information
Journal of Veterinary Clinics / v.20, no.2, 2003 , pp. 259-262 More about this Journal
Abstract
A 13-year old male dog with right forelimb lameness, invisible swelling, anorexia and mild depression was referred to Veterinary leaching Hospital, College of Veterinary Medicine, Kyungpook National University. On forelimb radiographic views, periosteal and endosteal proliferation and cortical lysis and extremely aggressive and amorphous periosteal reactions were located along the metaphyseal region of the proximal humerus. Cytologic and histopathologic examinations after amputation showed anaplastic mesenchymal cells that produced osteoid changes, poorly differentiated osteoblast and osteoclast. And also, it included the neoplastic cells with large nucleoli, multiple nucleoli that differ in size and cytoplasm with several clear vacuoles. Based on the physical examination and laboratory, radiolographic, cytologic and histopathologic findings, this case was diagnosed as osteosarcoma of the proximal humerus.
Keywords
humerus; amputation; osteoblast; osteoclast; osteosarcoma; dog;
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1 High-dose methotrexate and leucovorin rescue in dogs with osteogenic sarcoma /
[ Cotter,S.M.;Parker,L.M. ] / Am J Vet Res
2 Results of surgical treatment in 65dogs with osteosarcoma /
[ Brodey,R.S.;Abt,D.A. ] / J Am Vet Med Assoc
3 Limb-sparing treatment for osteosarcoma in dogs /
[ LaRue,S.M.;Withrow,S.J.;Powers,B.E.;Wrigley,G.H.;Gillette,E.L.;Schwarz,P.D.;Straw,R.C.;Richter,S.L. ] / J Am Vet Med Assoc
4 Osteogenic sarcoma and cisplatin chemotherapy in dogs: 16 cases(1986-1989) /
[ Kraegel,S.A.;Madewell,B.R.;Simonson,E.;Gregory,C.R. ] / J Am Vet Med Assoc
5 Prognosis for dogs with appendicular osteosarcoma treated by amputation alone:162 cases(1978-1988) /
[ Spodnick,G.J.;Berg,J.;Rand,W.M.;Schelling,S.H.;Couto,G.;Harvey,H.J.;Henderson,R.A.;MacEwen,G.;Mauldin,N.;McCaw,D.L. ] / J Am Vet Med Assoc
6 Evaluation of single-agent chemotherapy for treatment of clinically evident osteosarcoma metastasis in dogs:45 cases(1987-1991) /
[ Ogilvie,G.K.;Strqw,R.C.;Jameson,V.J.;Walters,L.M.;Lafferty,M.H.;Powers,B.E. ] / J Am Vet Med Assoc
7 Bone sarcomas associated with multifocal medullary bone infarction in dogs /
[ Dubielzig,R.R.;Biery,D.N.;Brodey,R.S. ] / J Am Vet Med Assoc
8 Extraskeletal osteosarcomas in dogs:A retrospective study of 169 cases(1986-1996) /
[ Langenbadh,A.;Anderson,M.A.;Dambach,D.M.;Sorenmo,K.U. ] / J Am Anim Hosp Assoc
9 Resection of pulmonary metastasis in canine osteosarcoma:36 Cases(1983-1992) /
[ O'brien,M.G.;Straw,R.C.;Withrow,S.J.;Powers,B.E.;Jameson,V.J.;Lafferty,M.;Ogilvie,G.K.;LaRue,S.M. ] / Vet Surg   DOI   ScienceOn
10 Canine axial skeletal osteosarcoma: A retrospective study of 116 cases(1986-1989) /
[ Heyman,S.J.;Diefenderfer,D.L.;Goldschmidt,M.H.;Newton,C.D. ] / Vet Surg   DOI   ScienceOn
11 Fracture-associated sarcoma in the dog /
[ Steven,S.;Holm,R.B.;Pohler,O.E.M.;Fetter,A.W.;Olmscead,M.L.;Wind,A.P. ] / J Am Vet Med Assoc
12 Tumors of the skeletal system /
[ Dornell,W.S.;Straw,R.C.;Withrow,S.J. ] / Small animal clinical oncology(3rd ed.)
13 Osteosarcoma in dogs:A study of previous trauma, fracture and fracture fixation /
[ Knecht,C.D.;Priester,W.A. ] / J Am Anim Hosp Assoc
14 Evaluation of survival times after limb amputation, with and without subsequent administration of cisplatin, for treatment of appendicular osteosarcoma in dogs: 30cases(1979-1990) /
[ Thompson,J.P.;Fugent,M.J. ] / J Am Vet Med Assoc
15 Treatment of dogs with osteosarcoma by administration of cisplatin after amputation or limb-sparing surgery:22 cases(1987-1990) /
[ Berg,J.;Weinstein,M.J.;Schelling,S.H.;Rand,W.M. ] / J Am Vet Med Assoc
16 Other diseases of bones and joints /
[ Hedlund,C.S.;Hulse,D.A.;Johnson,A.L.;Seim,H.B.;Willard,M.D.;Carroll,G.L. ] / Small animal surgery(2nd ed.)
17 Bone tumors versus bone infections /
[ Thrall,D.E. ] / Texbook of veterinary diagnostic radiology(4th ed.)
18 Use of cisplatin for treatment of appendicular osteosarcoma in dogs /
[ Shapiro,W.;Fossum,T.W.;Kitchell,B.E.;Couto,C.G.;Theilen,G.H. ] / J Am Vet Med Assoc