Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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Conservative surgical approach to aggressive benign odontogenic neoplasm: a report of three cases

  • Kumar, Vijay (Department of Oral and Maxillofacial Surgery, R. D. Dental Hospital & Research Center)
  • Received : 2014.08.03
  • Accepted : 2014.09.03
  • Published : 2015.02.28
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Abstract

Aggressive benign odontogenic neoplasms have substantial potential to grow to an enormous size with resulting bone deformities, and they often invade adjacent tissues and spread beyond their normal clinical and radiographic margins; as such, they have a high rate of recurrence. Historically, management (conservative versus aggressive) on the basis of clinical, radiographic and/or histopathologic characteristics has been controversial. However, recent advances in the understanding of the biological features of these lesions may provide greater evidence of the benefits of conservative management. Three patients with different complaints and final histopathologic diagnoses were enrolled in the study. All three cases were treated by a single operator with similar conservative surgical procedures. During follow-up, the patients had uneventful secondary healing and bone regeneration, less packing time than previously reported, no clinical or radiographic evidence of recurrence and no apparent deformity. The aggressive behavior of these lesions requires long clinical and radiographic follow-up. Conservative surgical management may be an option to reduce recurrence and morbidity and increase the probability of uneventful secondary healing and bone regeneration.

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References

  1. Gupta N, Saxena S, Rathod VC, Aggarwal P. Unicystic ameloblastoma of the mandible. J Oral Maxillofac Pathol 2011;15:228-31. https://doi.org/10.4103/0973-029X.84511
  2. Abdullah WA. Surgical treatment of keratocystic odontogenic tumour: a review article. Saudi Dent J 2011;23:61-5. https://doi.org/10.1016/j.sdentj.2011.01.002
  3. Yildirim G, Ataoglu H, Kalayci A, Ozkan BT, Kucuk K, Esen A. Conservative treatment protocol for keratocystic odontogenic tumour: a follow-up study of 3 cases. J Oral Maxillofac Res 2010;1:e7.
  4. Hasegawa T, Imai Y, Takeda D, Yasuoka D, Ri S, Shigeta T, et al. Retrospective study of ameloblastoma: the possibility of conservative treatment. Kobe J Med Sci 2013;59:E112-21.
  5. Kahairi A, Ahmad RL, Islah LW, Norra H. Management of large mandibular ameloblastomas: a case report and literature reviews. Arch Orofac Sci 2008;3:52-5.
  6. Giuliani M, Grossi GB, Lajolo C, Bisceglia M, Herb KE. Conservative management of a large odontogenic keratocyst: report of a case and review of the literature. J Oral Maxillofac Surg 2006;64:308-16. https://doi.org/10.1016/j.joms.2005.10.013
  7. Zhou H, Hou R, Ma Q, Wu K, Ding Y, Qin R, et al. Secondary healing after removal of large keratocystic odontogenic tumor in the mandible: enucleation followed by open packing of iodoform gauze. J Oral Maxillofac Surg 2012;70:1523-30. https://doi.org/10.1016/j.joms.2011.12.021
  8. Hellstein J, Hopkins T, Morgan T. The history and mystery of Carnoy's solution: an assessment of the need for chloroform. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:e24.
  9. Kalaskar R, Unawane AS, Kalaskar AR, Pandilwar P. Conservative management of unicystic ameloblastoma in a young child: report of two cases. Contemp Clin Dent 2011;2:359-63. https://doi.org/10.4103/0976-237X.91804
  10. Mizokami F, Murasawa Y, Furuta K, Isogai Z. Iodoform gauze removes necrotic tissue from pressure ulcer wounds by fibrinolytic activity. Biol Pharm Bull 2012;35:1048-53. https://doi.org/10.1248/bpb.b11-00016
  11. Freedman M, Stassen LF. Commonly used topical oral wound dressing materials in dental and surgical practice--a literature review. J Ir Dent Assoc 2013;59:190-5.
  12. Maria A, Sharma Y, Chabbria A. Marsupialization as a treatment option of a large odontogenic keratocyst: a case report with the review of literature. People's Journal of Scientific Research 2012;5:46-51.
  13. Dolanmaz D, Etoz OA, Pampu A, Kalayci A, Gunhan O. Marsupialization of unicystic ameloblastoma: a conservative approach for aggressive odontogenic tumors. Indian J Dent Res 2011;22:709-12. https://doi.org/10.4103/0970-9290.93461
  14. Ramesh RS, Manjunath S, Ustad TH, Pais S, Shivakumar K. Unicystic ameloblastoma of the mandible--an unusual case report and review of literature. Head Neck Oncol 2010;2:1. https://doi.org/10.1186/1758-3284-2-1
  15. Park SH, Kim NK, Kim KH, Kang SH, Park HS, Kim HJ, et al. Postoperative recurrences of odontogenic keratocyst: the behavior and proposal of critical follow-up period. J Korean Assoc Oral Maxillofac Surg 2008;34:456-9.
  16. Shin MY, Lee HK, Choi JW, Shin SS, Park YH, Park JW. Literature review and case report: the conservative treatment of unicystic ameloblastoma. J Korean Assoc Oral Maxillofac Surg 2005;31:70-3.
  17. Guler N, Sencift K, Demirkol O. Conservative management of keratocystic odontogenic tumors of jaws. ScientificWorldJournal 2012;2012:680397.
  18. Lee PK, Samman N, Ng IO. Unicystic ameloblastoma--use of Carnoy's solution after enucleation. Int J Oral Maxillofac Surg 2004;33:263-7. https://doi.org/10.1006/ijom.2003.0496
  19. Carneiro JT, Guerreiro Rodrigues Couto AP, Dias Carreira AS. Use of gas combination cryosurgery for treating ameloblastomas of the jaw. J Craniomaxillofac Surg 2012;40:e342-5. https://doi.org/10.1016/j.jcms.2012.01.017
  20. Hadziabdic N, Sulejmanagic H, Selimovic E, Sulejmanagic N. Therapeutic approach to large jaw cysts. HealthMed 2011;5:1793-9.

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