• 한국식품영양과학회지
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• 제23권4호
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• pp.568-571
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• 1994

This study was conducted to investigate the effect of Platycodi radix Saponin(PRS) on the reduction of lipid status in rats fed on high fat diet for 6 weeks after which lipid contents were measured in serum , liver and feces. The results obtained from this study are as follows : That the levels of total lipid, total cholesterol and triglyceride in serum and liver were significantly lower in the PRS group as compared with the control group. The contents of total lipid and total cholesterol excreted in the feces were tended to be slightly increase in PRS group compared to the control group, which were not significant.

• 전자공학회논문지B
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• 제31B권5호
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• pp.12-25
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• 1994

A two dimensional constant geometry FFT algorithms and architectures with shuffled inputs and normally ordered outputs are presented. It is suitable for VLSI implementation because all buterfly stages have identical, regular structure. Also a methodology using shuffled FFT inputs and outputs to halve the number of butterfly stages connected by a global interconnection which requires much area is presented. These algorithms can be obtained by shuffling the row and column of a decomposed FFT matrix which corresponds to one butterfly stage. Using non-recursive and recursive pipeline, the degree of serialism and parallelism in FFT computation can be adjusted. To implement high performance high radix FFT easily and reduce the amount of interconnections between stages, the method to build a high radix PE with lower radix PE 's is discussed. Finally the performances of the present architectures are evaluated and compared.

• 대한한의학회지
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• 제18권1호
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• pp.411-429
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• 1997

Recent survey shows that chronic liver disease such as chronic hepatitis, liver cirrhosis and hepatoma is the third leading causes for death in Korea. In oriental medicine, viral hepatitis is related to Hwangdal(黃疸) and alcoholic liver disease is related to Joosang(酒傷). ARTEMISIAE HERBA and PUERARIAE RADIX have long been used in treating those symptoms. This study was done to evaluate the effect of AR1EMISIAE HERBA and PUERARIAE RADIX on viral and alcoholic hepatitis. ARTEMISIAE HERBA and PUERARIAE RADIX were decocted respectively with water and followed by vaccum evaporation. The solution was diluted to adequate concentration. Sprague-Dawley rats were used in this experiment. Each group was given PUERARIAE RADIX or ARTEMISIAE HERBA solution orally and CCl4, d-galactosamine or alcohol was given orally 30 minutes later. After 24 hours of starvation, blood samples were taken to check serum GOT, GPT, LDH and ALP activities, TC, TG, glucose and BUN levels. These results show that ARTEMISIAE HERBA has better effect on liver injury induced by d-Galactosamine than PUERARIAE RADIX and that both ARTEMISIAE HERBA and PUERARlAE RADIX have good effect on acute alcoholic liver disease while in the liver injury induced by $CCl_{4}$, PUERARIAE RADIX has better inhibitory effect on serum AST, ALT and ALP levels and ARTEMISIAE HERBA has better inhibitory effect on serum total cholesterol and triglyceride. And the result that high concentration group has better effect shows these effects are concentration-dependent. Further study on the mechanism of these herbs is still required.

• 대한본초학회지
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• 제33권2호
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• pp.29-43
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• 2018

Objectives : Araliae Continentalis Radix(AC) is a medicinal herb belonging to the drug efficacy group treating musculoskeletal disorders(MSD) with anti-inflammatory, analgesic and antipyretic action. However, due to morphologic and onomastic similarity, adulterants(Angelicae Pubescentis Radix: AP, Gypsophilae Oldhamianae Radix: GO, Levistici Officinalis Radix: LO) have been included or replaced the standard. Methods : Multilateral methods were carried out on the identification of AC and its adulterants. Macroscopic and microscopic characteristics were observed by using stereoscope and microscope. For the comparison of chromatogram pattern, standard compounds were analyzed simultaneously using high performance liquid chromatography. Results : 1. The macroscopic identification of original plants was determined by the phyllotaxis type, the inflorescence type, the leaf margin and the color of flowers. The macroscopic identification of herbal materials was examined by oil spots, the cambium, heteromorphic vascular bundles, and the pholem. 2. For the microscopic identification, the fact whether its xylem ray is proliferated or not was first determined. Then medicinal herbs were secondly divided by cellular inclusions, fiber bundles, the distribution of secretary canals and the shape of cambium. 3. AC and its adulterants showed different chromatographic fingerprints. AC was containing continentalic acid and kaurenoic acid. AP was containing osthole and columbianadin. LO was containing osthole and falcarindiol. None of the compounds were found in GO. Conclusions : This recent identification keys of might be helpful to discriminate the pharmacopoeia standard and its adulterants for the right usage in clinics.

• 혜화의학회지
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• 제23권1호
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• pp.93-104
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• 2014

Glycyrrhizae Radix et Rhizoma has been extensively used by human beings as a medicinal herb as well as natural sweetener. In this study, we performed quantification analysis of three major constituents including liquiritin, glycyrrhizin, and glycyrrhetinic acid in the 70% ethanol extracts of non-processed Glycyrrhizae Radix et Rhizoma and processed Glycyrrhizae Radix et Rhizoma using a high-performance liquid chromatography coupled with photodiode array detector. The analytical column for separation of the 3 constituents used a Gemini C18 column kept at $40^{\circ}C$ by the gradient elution of two mobile phase. The amounts of liquiritin, glycyrrhizin, and glycyrrhetinic acid in non-processed Glycyrrhizae Radix et Rhizoma were 2.57%, 3.52%, and not detected. After processing by roasting, the best roasting temperature and time of iquiritin, glycyrrhizin, and glycyrrhetinic acid were $160^{\circ}C$-15 min (2.46%), $160^{\circ}C$-15 min (3.67%), and $240^{\circ}C$-15 min (0.76%), respectively.

• JSTS:Journal of Semiconductor Technology and Science
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• 제15권1호
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• pp.77-84
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• 2015

This paper presents the design of a low-power, low area 256-radix 16-bit crossbar switch employing a 2D Hyper-X network topology. The Hyper-X crossbar switch realizes the high radix of 256 by hierarchically combining a set of 4-radix sub-switches and applies three modifications to the basic Hyper-X topology in order to mitigate the adverse scaling of power consumption and propagation delay with the increasing radix. For instance, by restricting the directions in which signals can be routed, by restricting the ports to which signals can be connected, and by replacing the column-wise routes with diagonal routes, the fanout of each circuit node can be substantially reduced from 256 to 4~8. The proposed 256-radix, 16-bit crossbar switch is designed in a 65 nm CMOS and occupies the total area of $0.93{\times}1.25mm^2$. The simulated worst-case delay and power dissipation are 641 ps and 13.01 W when operating at a 1.2 V supply and 1 GHz frequency. In comparison with the state-of-the-art designs, the proposed crossbar switch design achieves the best energy-delay efficiency of $2.203cycle/ns{\cdot}fJ{\cdot}{\lambda}2$.

• 생약학회지
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• 제46권4호
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• pp.295-302
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• 2015

Cynanchi wilfordii Radix roots have been utilized as traditional medicine for variety of diseases including diabetes mellitus, aging progression and scavenging free radicals, enhancing immunity, reducing high serum cholesterol, and anti-tumor activity. However, the mechanisms underlying this effect remain poorly understood. The principal objective of this study was to determine the effect of cynandione A on osteoclast cells. Thus, we was isolated cynandione A from Cynanchi wilfordii Radix roots and evaluated the effect of cynandione A on receptor activator of nuclear factor-${\kappa}B$ ligand (RANKL)-induced osteoclast differentiation. We found that cynandione A significantly inhibited osteoclast differentiation stimulated-RANKL in RAW 264.7 cells. Cynandione A conspicuously inhibited the mRNA and protein expression of matrix metallopeptidase 9 (MMP-9), tartrate-resistant acid phosphatase (TRAP) in cynandione A treated with RANKL. Taken together, our results demonstrated that Cynanchi Wilfordii Radix may be useful treatment option of bone-related disease such as osteoporosis leads to fracture of bone and rheumatoid arthritis.

• 생약학회지
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• 제36권3호통권142호
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• pp.195-200
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• 2005

Smilacis Chinae Radix is root of Smilax china L.. It has been known as a korean folk medicine for anti-inflammatory, anti-microbial diuresis, detoxification and relieving enteropathy as diarrhea. Reactive oxygen species(ROS) are continuously produced at a high rate as a by-product obtained in the aerobic metabolism. A major portion of living organisms has defense system as superoxide dismutase or catalase against damage produced by ROS. Several lines of evidence provided that ROS appears to cause to develop aging and various diseases. In this study, we have investigated the antioxidant activities of Smilacis Chinae Radix in order to screen the antioxidant substances from natural products. As a result, EtOAc extract of Smilacis Chinae Radix exhibited potent antioxidant effect on various antioxidant experiment. The major components of antioxidant activity were isolated from EtOAc extract of Smilacis Chinae Radix. Their structure of compounds were identified as quercetin and (-)-epicatechin by spectroscopic evidence, respectively.

• 전기전자학회논문지
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• 제25권4호
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• pp.697-702
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• 2021

고속 푸리에 변환(Fast Fourier Transform, FFT)은 다양한 응용처에서 널리 사용되는 주요 신호처리 블록이다. 일반적으로 1024 포인트 이상의 긴 FFT 처리의 경우 높은 SQNR(Signal-to-Quantization Ratio)를 유지하면서도 낮은 하드웨어 복잡도의 구현이 매우 중요하다. 본 논문에서는 낮은 복잡도의 FFT 알고리즘과 간단한 동적스케일링 기법을 제시한다. 이를 통해 2048 포인트 FFT연산에 대해서 널리 알려진 radix-2 알고리즘에 비해 곱셉기의 수를 절반으로 줄일 수 있으며, 또한 twiddle factor를 저장하기 위해 필요한 테이블의 크기를 radix-2 및 radix-2² 알고리즘에 비해 각각 35% 및 53%로 축소할 수 있다. 그리고 내부 데이터의 폭을 점진적으로 늘리지 않고서도 55dB 이상의 높은 SQNR을 달성하는 것을 확인하였다.

• 한국정보전자통신기술학회논문지
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• 제13권1호
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• pp.42-47
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• 2020

OFDM 기반 초고속 통신시스템을 위한 IFFT/FFT 프로세서는 저면적 저전력이면서 데이터 처리량이 높고 프로세싱 지연이 적어야 한다. 따라서, 파이프라인과 병렬처리를 적용한 radix-2k 알고리즘 기반 MDF(multipath delay feedback) 구조가 적합하다. 기존의 MDF 구조에서 입력신호의 워드길이에 비례하여 커지는 피드백 메모리는 면적과 전력소모가 크다. 본 논문에서는 OFDM 응용을 위한 radix-22 MDF IFFT 프로세서의 피드백 메모리 크기 감소 방법을 제안한다. MDF 구조에서 첫 두 스테이지의 피드백 메모리의 크기는 전체 피드백 메모리의 75%를 차지하므로 첫 두 스테이지의 피드백 메모리 크기 감소에 초점을 맞춘다. OFDM 전송에서 IFFT 입력신호는 변조데이터와 파일럿과 널 신호로 구성된다는 특징을 이용하여 변조데이터와 파일럿/널 신호를 각각 부호있는 정수로 매핑하여 입력신호의 워드길이를 감소시키는 방법을 제안한다. 시뮬레이션을 통해 제안한 방법이 기존 방법보다 피드백 메모리의 크기를 약 39%까지 감소시킬 수 있음을 보인다.