• Journal of Korean Neurosurgical Society
• /
• v.30 no.6
• /
• pp.683-687
• /
• 2001

Objective : Angiogenesis, the proliferation of capillary endothelial cells, is a vital component in the development, progression, and metastasis of many human tumors. Vascular endothelial growth factor(VEGF) is an endothelial cell-specific mitogen and induces angiogenesis and vascular permeability. The features of glioblastoma, distinct from low grade astrocytomas, are the presence of necroses and vascular endothelial proliferation. In this study, we investigated VEGF expression in the different grades of astrocytomas and determined whether VEGF expression correlates with development of glioblastoma and progression of astrocytomas. Patients and Methods : Forty seven patients with astrocytic tumors(24 males and 23 females), aged 3 to 65 years, were evaluated. Immunohistochemical staining was carried out using labelled streptavidin biotin method and primary antibody was a antirabbit polyclonal Ab against N-terminus region of VEGF165(Oncogene research product, MA, USA). Immunoreactivity(IR) was classified into no IR(absent or a trace of stain), moderate IR and intense IR by level of staining amount and intensity. Results : Six pilocytic astrocytomas showed 3 no IR and 3 moderate IR, 10 astrocytomas showed 2 no IR, 6 moderate IR and 2 intense IR, 12 anaplastic astrocytomas showed I no IR, 7 moderate IR and 4 intense IR and 19 glioblastomas showed 1 no IR, 11 moderate IR and 7 intense IR. Immunoreactivity was significantly different between low and high grade of tumors but there was no significant difference between anaplastic astrocytomas and glioblastomas. Gemistocytic tumor cells represented the predominent VEGF-immunoreactive cell types, as compared with compactly-arranged small tumor cells. In glioblastomas VEGF IR was observed in both perinecrotic and vital tumor areas. Conclusion : VEGF seems to be a important angiogenic factor in anaplastic astrocytomas and glioblastomas and VEGF expression may contribute to neovascularization of human astrocytomas.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.2
• /
• pp.559-562
• /
• 2012

Serum alpha-fetoprotein (AFP) is a significant marker for clinical diagnosis and prognosis evaluation in hepatocellular carcinoma (HCC) patients. However, some proportion of liver cancer patients are AFP-negative (AFP ${\leq}$20ng/ml). In order to study the differences between clinicopathological factors and prognosis of alpha-fetoprotein negative and positive patients, a total of 114 cases (41 AFP-negative and 73 AFP-positive) were selected for our research. By systematically statistical analysis, the results demonstrated that compared with AFP-negative patients, AFP-positive examples were more likely to feature cirrhosis nodules, non-complete neoplasm capsules, and a poor Edmondson-steiner grade. Furthermore, AFP-negative patients demonstrated a favorable long-term prognosis. By univariate analysis and multivariate analysis with Cox's proportional hazards model, multiple tumors were found to be independent risk factors for worse survival of AFP negative patients; however, less tumor-free margins, multiple tumors and Edmondson-steiner grades III/IV, proved to be independent risk factors leading to a poor prognosis of AFP positive cases. Finally, we can infer that high levels of AFP signify a highly malignant tumor and unfavorable prognosis.

• Journal of agricultural medicine and community health
• /
• v.22 no.1
• /
• pp.43-48
• /
• 1997

To exam infestation rate and removal rate of head louse, we did delousing at 27 primary schools and 19 kindergartens established as an annex to the primary school in Namwon-shi, Jollabuk-do, Korea, from May to December 1995. Total of 3123 subjects were examined ed for the presence of head lice and nits The overall infestation rate was 9.6%, 9.5% in primary school children and 10.1% in kindergarten children. Among 299 infested children, 55 children evaluated by live nit had louse, and 79 children had dead nit. According to distractive research, Ibaek-myon and Songdong-myon revealed high infestation rate of 27.3%, and 21.7% respectively. Infestation rate of primary school was 0 to 50.9%, kindergarten was 0 to 100%. Infestation rate of female children were higher than male in all grades. When we executed one time treatment with PARA$^{(R)}$ aerosol(bioallethrin with piperonyl butoxide), treatment rate of 65.1% was examined, 82.8% was examined in three times of treatment. We concluded that 3 times of treatments interval of 14 days were more effective than one time in the case of treatment of only infested children. In order to prevent the spread of head lice, education of school hygiene and suitable delousing attempts should be executed in the present situation.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.16 no.1
• /
• pp.47-53
• /
• 2005

Objectives : Few studies have examined the relation between the attachment styles of the primary caregivers and the behavioral problems of their children. This study was performed to identify the impact of the insecure parental attachment patterns on the development of their higher grades elementary school children's psychiatric manifestations and disorders. Methods : 504 higher elementary pupils and their primary caretakers were included in our study. Relationship Questionnaire, Kovacs Children's Depression Inventory, Spielberger's State-Trait Anxiety Inventory for children, and Korean Child Behavior Checklist were applied to them. Results : The grade-school children of the parents who belonged to preoccupied attachment type revealed higher Withdrawn, Anxious/depressed, Social Problems, Attention Problems, Delinquent Problems, Aggressive Problems, Internalizing Problems, Externalizing Problems, Total Behavioral Problems scores than ones of securely attached parents (p<0.01). Internalizing Problems score of preoccupied parents' children was highest, and one of avoidant and secure typed parents' kids followed in order (p=0.004) . More youngsters revealed Total Behavior Problem score high enough to clinically meaningful level in insecure parental attachment style than in secure one (p=0.038). Higher CDI score in insecure parental group was reported than in secure one (p=0.040). Conclusion : Parental insecure attachment can be associated with the development of the behavioral problems and psychiatric illness of their children.

• Journal of Korean Home Economics Education Association
• /
• v.27 no.1
• /
• pp.13-29
• /
• 2015

This study examined whether any differences were found in body comparison, body satisfaction, and appearance management behaviors according to socialcultural attitudes toward appearance among male and female adolescents in Gwangju and Jeolla province. It was conducted by a self-report survey of 598 male and female students in eigth and eleventh grades in Gwangju and Jeonnam province, South Korea. The collected survey data were analyzed by Cronbach's ${\alpha}$, Factor analysis, ${\chi}^2$ test, K-means cluster analysis, t-test, one-way ANOVA, Duncan's grouping using SPSS/PC WIN 19.0 statical program. The results were as the following: Adolescents perceived and internalized more highly than the common level the socialcultural value toward appearance, especially for female, and by age, juniors in high school than in middle school. Socialcultural attitudes toward appearance could be classified into four categories: 'Accepted type', 'internal type', 'aware type', and 'unaccepted type'. Students who were classified as 'accepted type', and 'internal type' showed lower level of body satisfaction and compared their bodies more often with others. They also actively received appearance management behaviors. Therefore, they showed positive attitude toward cosmetic surgery and functional garments. They also worked hard to reduce their weights just to show off to others. In conclusion, it is necessary for education programs to protect self-esteem of adolescents from the socialcultural distortion to appearance.

• Asian-Australasian Journal of Animal Sciences
• /
• v.29 no.8
• /
• pp.1083-1094
• /
• 2016

Carcass and price traits of 72,969 Hanwoo cows, bulls and steers aged 16 to 80 months at slaughter collected from 2002 to 2013 at 75 beef packing plants in Korea were analyzed to determine heritability, correlation and breeding value using the Multi-Trait restricted maximum likelihood (REML) animal model procedure. The traits included carcass measurements, scores and grades at 24 h postmortem and bid prices at auction. Relatively high heritability was found for maturity ($0.41{\pm}0.031$), while moderate heritability estimates were obtained for backfat thickness ($0.20{\pm}0.018$), longissimus muscle (LM) area ($0.23{\pm}0.020$), carcass weight ($0.28{\pm}0.019$), yield index ($0.20{\pm}0.018$), yield grade ($0.16{\pm}0.017$), marbling ($0.28{\pm}0.021$), texture ($0.14{\pm}0.016$), quality grade ($0.26{\pm}0.016$) and price/kg ($0.24{\pm}0.025$). Relatively low heritability estimates were observed for meat color ($0.06{\pm}0.013$) and fat color ($0.06{\pm}0.012$). Heritability estimates for most traits were lower than those in the literature. Genetic correlations of carcass measurements with characteristic scores or quality grade of carcass ranged from -0.27 to +0.21. Genetic correlations of yield grade with backfat thickness, LM area and carcass weight were 0.91, -0.43, and -0.09, respectively. Genetic correlations of quality grade with scores of marbling, meat color, fat color and texture were -0.99, 0.48, 0.47, and 0.98, respectively. Genetic correlations of price/kg with LM area, carcass weight, marbling, meat color, texture and maturity were 0.57, 0.64, 0.76, -0.41, -0.79, and -0.42, respectively. Genetic correlations of carcass price with LM area, carcass weight, marbling and texture were 0.61, 0.57, 0.64, and -0.73, respectively, with standard errors ranging from ${\pm}0.047$ to ${\pm}0.058$. The mean carcass weight breeding values increased by more than 8 kg, whereas the mean marbling scores decreased by approximately 0.2 from 2000 through 2009. Overall, the results suggest that genetic improvement of productivity and carcass quality could be obtained under the national scale breeding scheme of Korea for Hanwoo and that continuous efforts to improve the breeding scheme should be made to increase genetic progress.

• Korean Journal of Health Education and Promotion
• /
• v.21 no.1
• /
• pp.69-84
• /
• 2004

This study was conducted to identify actual dental care status, levels of knowledge, attitudes, and behaviors about dental health, and dental health conditions in elementary students; and examine the relationships between the levels of knowledge, attitudes, behaviors, and dental health conditions for 427 students in their sixth grades from six elementary schools in Pusan area from November 1st to December 5th, 2002. The data was collected through a structured study questionnaire and through dental checkups by dentists and was analyzed into frequency, percentage, mean, standard deviation, t-test, one-way ANOVA and Pearson's correlation analysis using SPSS program. The main results of this study were summarized as follows： 1) The levels of knowledge, attitudes, behaviors about dental health was found to be high as mean score 18.75 points (64.7％) in knowledge, 17.86 points (59.5％) in attitudes, and 31.64 points (67.3％) in behaviors. Therefore they were found to care a lot about their dental health. The indices of dental health conditions were found to be low as mean score 0.87 pieces (3.1％) of treated teeth, 1.27 pieces (4.5％) of teeth to be treated, 7.64％ of the DMFT rate and 0.43 points (7.2％) of the simplified oral hygiene index. Therefore their condition of dental health was found to be very clean. 2) The relationships among the knowledge, attitudes, and behaviors about dental health showed a weak level of positive correlations. Among the conditions of dental health, treated teeth and the DMFT rate showed a moderate level of positive correlation； and treated teeth and the simplified oral hygiene index showed weak level of positive correlation. 3) The condition of dental health of the subjects of this study was found to be good and dental care was properly done when there was participation of parents and school health educators in dental care. It tells us that dental education is required not only for children but also for their parents. As there were significant correlations between knowledge, attitudes, and behaviors about children's dental heath, school health educators should encourage students to have continuous dental care habits for lifelong dental health with repetitive education, rather than to deliver simple knowledge to students during dental health education.

• Journal of Science Education
• /
• v.37 no.3
• /
• pp.538-549
• /
• 2013

This study investigated the preservice and inservice elementary teachers' perceptions on professionalism of teaching profession, professionalism of science teaching, and their self-efficacy on science teaching. For this study, 64 sophomore, 53 senior preservice teachers and 23 elementary teachers who were also graduate students were participated. The questionnaires consisted of 5 Likert scaled and descriptive items about the professionalism of teaching profession, professionalism of science teaching, and self-efficacy on science teaching. The results showed that some areas of the professionalism of teaching profession had significant differences between the grades in preservice teachers and/or inservice teachers. Most preservice teachers and teachers thought that they need to have professional ability, but not a few teachers thought it was not necessary to have professionalism of science teaching as a elementary teacher, even though their major was science education. The teachers who had higher perceptions on the needs of the professionalism of science teaching showed high self-efficacy on science teaching.

• Communications of Mathematical Education
• /
• v.31 no.3
• /
• pp.349-366
• /
• 2017

The 2015 revised curriculum is an integrated curriculum that reflects national and societal needs to foster creative convergent talent in the school curriculum. Along with these changes, the Ministry of Education introduced a system to change the major from 2017 to the fourth year of university. Therefore, each university should prepare to reflect the curriculum and institutional change before welcoming students who have completed the 2015 revised curriculum. The university needs to study the countermeasures for implementing the 2015 revised curriculum and expanding the period of major change when preparing the curriculum and contents of the calculus courses that freshmen take. Handong University has been studying the operation methods of new students who want to decide their major at the first grade, such as operating calculus courses at various levels and allocating appropriate proportions of calculus for preliminary examinations. This case is similar to the basic purpose of the revised curriculum in 2015, so it can suggest implications for the operation of the university calculus class after the curriculum revision. In this paper, we have analyzed the results of the recent freshman mathematics test for the recent 5 years and the students' calculus grades and compared them with the contents of the calculus curriculum operated by Handong University and the 2015 revised higher mathematics curriculum. As a result, we proposed five classes of calculus suitable for college major and it was found that the calculus curriculum should include the missing quadratic method in the 2015 revised curriculum.

• Journal of the Korean Wood Science and Technology
• /
• v.13 no.3
• /
• pp.41-48
• /
• 1985

In near future about 500,000 hectares of Japanese larch and pitch pine need thinning to improve crop-tree spacing and reasonable species composition in Korea. Although thinned trees show very little high quality wood, in fact, all the sawed products are suitable for construction and farming materials. Studies on the utilization of thinned small-diameter trees have been implemented in order to increase lumber yield and display the skeleton of farm buildings. The results obtained in this study were summarized as follows: 1. According to Korean Conifers Log Grading System, log grade 3 was 87.4 percent in Japanese larch bolts and 95.8 percent in pitch pine bolts from thinned trees. The ability to identify defects was essential for grading logs. 2. Cutting diagrams of sawing were developed for 1-sided sawing, 2-sided sawing and 3-sided sawing by small end diameter class of bolt and cutting sizes also were found to use effectively lumber with wane. 3. Lumber recovery of Pitch pine was a little higher than that of Japanese larch. The maximum lumber yields of pitch pine by sawing patterns were 87.2 percent for 1-sided sawing, 80.8 percent for 2-sided sawing an 64.1 percent for 3-sided sawing, up yield compared with 58.1 percent for 4-sided sawing. The lumber yield of 1, 2 and 3-sided sawing significantly was higher value than that of 4-sided sawing. 4. Lumber was inspected and graded. Lumber quality of diameter class 12cm was a little better than that of diameter class 8cm, but 90 percent of lumber in diameter c1ass 16cm fell into grade 3. The lumber grade was classified by Korean standard grades of confiers lumber. 5. Lumber from 1, 2 and 3-sided sawing was used to build the skeleton of a farm house ($53m^2$) and greenhouse ($60m^2$) in order to display more efficient use of small diameter trees from thinning 6. Total volume of timber for building a farm house was $8.1m^3$ of imported timber. Timber of $7m^3$, 70 percent of total volume would be substituted imported timber for domestic timber.