• Communications for Statistical Applications and Methods
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• 제13권3호
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• pp.701-718
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• 2006

In cancer microarray experiments, the experimenter or patient which is nested in each experimenter often shows quite heterogeneous error variability, which should be estimated for identifying a source of variation. Our study describes a Bayesian method which utilizes clinical information for identifying a set of DE genes for the class of subtypes as well as assesses and examines the experimenter effect and patient effect which is nested in each experimenter as a source of variation. We propose a Bayesian multilevel mixed effect model based on analysis of covariance (ANACOVA). The Bayesian multilevel mixed effect model is a combination of the multilevel mixed effect model and the Bayesian hierarchical model, which provides a flexible way of defining a suitable correlation structure among genes.

• 한국통계학회:학술대회논문집
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• 한국통계학회 2000년도 추계학술발표회 논문집
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• pp.5-12
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• 2000

Meta-analysis refers to quantitative methods for combining results from independent studies in order to draw overall conclusions. We consider hierarchical models including selection models under a skewed heavy tailed error distribution and it is shown to be useful in such Bayesian meta-analysis. A general class of skewed elliptical distribution is reviewed and developed. These rich class of models combine the information of independent studies, allowing investigation of variability both between and within studies, and weight function. Here we investigate sensitivity of results to unobserved studies by considering a hierarchical selection model and use Markov chain Monte Carlo methods to develop inference for the parameters of interest.

• Management Science and Financial Engineering
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• 제12권1호
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• pp.65-77
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• 2006

This study proposes a Bayesian dynamic model in a hierarchical way to assess the time-varying effect of risk factors on the likelihood of corporate bankruptcy. For the longitudinal data, we aim to describe dynamically evolving effects of covariates more articulately compared to the Generalized Estimating Equation approach. In the analysis, it is shown that the proposed model outperforms in terms of sensitivity and specificity. Besides, the usefulness of this study can be found from the flexibility in describing the dependence structure among time specific parameters and suitability for assessing the time effect of risk factors.

• Communications for Statistical Applications and Methods
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• 제9권1호
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• pp.115-128
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• 2002

Hierarchical models are widely used for inference on correlated parameters as a compromise between underfitting and overfilling problems. In this paper, we take a Bayesian approach to analyzing hierarchical models and suggest a Markov chain Monte Carlo methods to get around computational difficulties in Bayesian analysis of the hierarchical models. We apply the method to a real data on smoking and lung cancer which are collected from cities in China.

• Communications for Statistical Applications and Methods
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• 제19권5호
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• pp.705-720
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• 2012

In this paper, we introduce a hierarchical Bayesian model to simultaneously estimate the thresholds of each 6 cities. It was noted in the literature there was a dramatic increases in the number of deaths if the mean temperature passes a certain value (that we call a threshold). We estimate the difference of mortality before and after the threshold. For the hierarchical Bayesian analysis, some proper prior distribution of parameters and hyper-parameters are assumed. By combining the Gibbs and Metropolis-Hastings algorithm, we constructed a Markov chain Monte Carlo algorithm and the posterior inference was based on the posterior sample. The analysis shows that the estimates of the threshold are located at $25^{\circ}C{\sim}29^{\circ}C$ and the mortality around the threshold changes from -1% to 2~13%.

• Journal of the Korean Data and Information Science Society
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• 제27권3호
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• pp.803-814
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• 2016

Recent times have seen an exponential increase in the amount of spatial data, which is in many cases associated with temporal data. Recent advances in computer technology and computation of hierarchical Bayesian models have enabled to analyze complex spatio-temporal data. Our work aims at modeling data of daily average nitrogen dioxide (NO2) levels obtained from 25 air monitoring sites in Seoul between 2003 and 2010. We considered an independent Gaussian process model and an auto-regressive model and carried out estimation within a hierarchical Bayesian framework with Markov chain Monte Carlo techniques. A Gaussian predictive process approximation has shown the better prediction performance rather than a Hierarchical auto-regressive model for the illustrative NO2 concentration levels at any unmonitored location.

• Journal of the Korean Data and Information Science Society
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• 제11권1호
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• pp.127-137
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• 2000

In this paper, we consider hierarchical Bayesian analysis for P(Y < X) using Gibbs sampler, where X and Y are independent normal distributions with unknown means and variances, respectively. Also numerical study using real data is provided.

• 응용통계연구
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• 제20권2호
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• pp.229-244
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• 2007

국내외에서 소지역 추정에 관한 많은 연구가 진행되고 있다. 보조 자료가 충분히 있는 경우 모형기반 추정법을 사용하는 것이 일반적이며 이 중에서 계층적 베이지안(Hierarchical Bayesian: HB) 추정법이 가장 좋은 것으로 알려져 있다. 그러나 보조 자료가 충분하지 않은 경우에는 모형 기반 추정법의 사용은 제한적이다. 최근 충분한 보조 자료가 없는 경우 공간 정보를 보조 자료로 사용하는 방법이 제안되었다. 본 논문에서는 공간통계량과 베이즈 접근방법을 활용한 모형기반의 소지역 통계량들을 모형 검진방법(Diagnostic method)들을 이용하여 비교 분석하였다. 분석에 사용된 자료는 2005년도 경제활동인구 조사이며 소지역(시,군,구)통계를 추정하여 비교하였다.

• 한국수자원학회논문집
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• 제46권1호
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• pp.13-24
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• 2013

본 연구에서는 계층적 Bayesian 기법을 이용한 새로운 지역빈도해석 모형을 개발하는데 목적이 있으며 이를 통해서 신뢰성 있는 매개변수를 추정과 동시에 지역빈도해석 절차의 불확실성 평가를 용이하게 접근할 수 있도록 하였다. 본 연구에서 제안되는 계층적 Bayesian 기반 지역빈도해석 모형(HBRFA)의 적합성을 평가하기 위해서 모의실험을 수행하였다. 즉, 10개의 모의 관측소를 대상으로 Monte-Carlo 모의를 통한 평가를 수행하였으며 전체적으로 HBRFA 모형이 기존 L-모멘트 방법에 비해 편의를 줄여주는 것으로 평가되었다. 특히 재현기간이 증가될수록 편의가 두드러지게 감소되는 것을 확인할 수 있었다. 전라북도의 6개 강우지점을 대상으로 HBRFA 모형과 기존 L-모멘트 기반 지역빈도해석 결과를 비교하였다. 계층적 Bayesian 모형의 특징을 평가하고자 매개변수의 Shrinkage 과정을 정량적으로 도출하여 제시하였으며 추정된 지역확률강수량이 기존 L-모멘트 기법과 유사한 결과를 갖는 것을 확인할 수 있었다. 더불어 빈도별 확률강수량의 불확실성을 정량적으로 제시할 수 장점을 확인할 수 있었다.

• Communications for Statistical Applications and Methods
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• 제26권2호
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• pp.205-216
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• 2019

Diagnostic tests in medical fields detect or diagnose a disease with results measured by continuous or discrete ordinal data. The performance of a diagnostic test is summarized using the receiver operating characteristic (ROC) curve and the area under the curve (AUC). The diagnostic test is considered clinically useful if the outcomes in actually-positive cases are higher than actually-negative cases and the ROC curve is concave. In this study, we apply the stochastic ordering method in a Bayesian hierarchical model to estimate the proper ROC curve and AUC when the diagnostic test results are measured in discrete ordinal data. We compare the conventional binormal model and binormal model under stochastic ordering. The simulation results and real data analysis for breast cancer indicate that the binormal model under stochastic ordering can be used to estimate the proper ROC curve with a small bias even though the sample sizes were small or the sample size of actually-negative cases varied from actually-positive cases. Therefore, it is appropriate to consider the binormal model under stochastic ordering in the presence of large differences for a sample size between actually-negative and actually-positive groups.