• BMB Reports
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• v.49 no.12
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• pp.662-670
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• 2016

The human oral cavity contains a highly personalized microbiome essential to maintaining health, but capable of causing oral and systemic diseases. Thus, an in-depth definition of "healthy oral microbiome" is critical to understanding variations in disease states from preclinical conditions, and disease onset through progressive states of disease. With rapid advances in DNA sequencing and analytical technologies, population-based studies have documented the range and diversity of both taxonomic compositions and functional potentials observed in the oral microbiome in healthy individuals. Besides factors specific to the host, such as age and race/ethnicity, environmental factors also appear to contribute to the variability of the healthy oral microbiome. Here, we review bioinformatic techniques for metagenomic datasets, including their strengths and limitations. In addition, we summarize the interpersonal and intrapersonal diversity of the oral microbiome, taking into consideration the recent large-scale and longitudinal studies, including the Human Microbiome Project.

• Journal of Preventive Medicine and Public Health
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• v.55 no.1
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• pp.1-9
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• 2022

An index that evaluates the health level of a population group considering both death and loss of function due to disease is called a summary measure of population health (SMPH). SMPHs are broadly divided into life year indices and life expectancy indices, the latter of which comprise healthy life expectancy (HLE). HLE is included as a policy target in various national and regional level healthcare plans, and the term "HLE" is commonly used in academia and by the public. However, the overall level of understanding of HLE-such as the precise definition of HLE and methods of calculating HLE-still seems to be low. As discussed in this study, the types of HLE are classified into disability-free life expectancy, disease-free life expectancy, quality-adjusted life expectancy, self-rated HLE, and disability-adjusted life expectancy. Their characteristics are examined to facilitate a correct understanding and appropriate utilization of HLE. In addition, the Sullivan method, as a representative method for calculating HLE, is presented in detail, and major issues in the process of calculating HLE, such as selection of the population group and age group, estimation of death probability, calculation of life years, and incorporation of health weights, are reviewed. This study will help researchers to select an appropriate HLE type and evaluate the validity of HLE research results, and it is expected to contribute to the vitalization of HLE research.

• The Journal of the Korean Society for Microbiology
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• v.17 no.1
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• pp.1-6
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• 1982

To investigate the annual distribution of hepatitis B surface antigen(HBs Ag) in healthy adults, this study was performed by means of counter-immunoelectrophoresis with sera obtained from 4,856 healthy adults who reside in Seoul and Gyunggi-Do area from January to December, 1981. The experimental procedures were same with the previous reports. The subjectives were consisted of two groups: one is mass life group(3.853 adults) and the other, home life group(1.003 adults). The results were as follows: 1. Among the 4.856 cases tested, 326 cases(6.71%) showed HBs Ag positive. HBs Ag positive rates in the group of mass life and home life were 6.51% and 7.48%, respectively. 2. It showed slightly high positive rates in the home life and long term duration group, and upper class group showed slightly high positive rate. 3. In seasonal variation, it showed relatively high positive rate(7.38%) in winter, and A blood group showed higher rate(7.60%) than the other blood groups. And then, boundary area of Seoul city showed slightly high positive rate(7.36%) in areal distribution.

• Journal of Microbiology and Biotechnology
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• v.28 no.4
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• pp.652-662
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• 2018

Diarrhea is a global disease with a high morbidity and mortality rate in children. In this study, 25 fecal samples were collected from children under 5 years old. Seven samples had been taken from healthy children without diarrhea and marked as the healthy control group; eight samples had been sampled from children with diarrhea caused by dyspepsia and defined as the non-infectious group; and ten samples had been taken from children with diarrhea induced by intestinal infections and identified as the infectious group. We detected the microbial communities of samples by using high-throughput sequencing of 16S rRNA genes. The proportion of aerobic and facultative anaerobic microbes in samples of the infectious group was much higher than in the non-infectious group. In addition, the relative abundance of Enterococcus in the healthy control group was significantly higher than in the non-infectious group and infectious group. This can be used as a potential diagnostic biomarker for diarrhea.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.47 no.5
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• pp.351-359
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• 2021

Objectives: Despite treatment, the pre-traumatic facial appearance of patients with maxillofacial fractures might not be able to be restored, and this difference can affect the person's quality of life (QoL). This study was designed to evaluate changes in QoL of people with maxillofacial fractures. Materials and Methods: The study population was comprised of participants with maxillofacial fracture and age- and sex-matched healthy controls without history of such fracture. QoL was measured using the World Health Organization Quality of Life BREF (WHOQOL-BREF) questionnaire, which was administered to the patients before treatment (Time 1), at 6 weeks post-treatment (Time 2), and at 12 weeks postoperatively (Time 3). The values were compared with those of healthy controls. The QoL was compared between closed reduction group and open reduction and internal fixation group. Results: The QoL scores of people with maxillofacial fracture before treatment were significantly lower (P=0.001) than those of healthy controls in all domains of the WHOQOL-BREF. The QoL scores in the psychological and social domains of patients with maxillofacial fracture at Time 3 were still lower than those of healthy controls (P=0.001). Conclusion: The QoL of patients with maxillofacial fracture was significantly reduced before treatment in all domains and remained reduced in both psychological and social domains weeks after treatment. Therefore, clinicians must be aware of and manage the residual psychosocial issues that can accompany the post-treatment period of maxillofacial injury.

• Journal of Families and Better Life
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• v.28 no.3
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• pp.167-178
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• 2010

The purpose of this study was to analyze the healthy family education, healthy family counseling, a healthy family culture, and healthy families integrated programs for single parent families in family support centers, The data collected came from 59 family support centers located in Seoul and Kyunggi-Do, Korea. Subjects included both single parents and their children. The children were of elementary school age. The types of programs were education, counseling, culture, and integrated program. Education programs were process separately for the parents and for the children. Counseling programs were mostly group-type program that aimed at improving the parent-children relationship. The contents included sections on anger management, reducing stress, enriching self-esteem. The culture programs involved experiences, camps that included cooking, watching movies, similar activities. Integrated programs involved respite support, rearing support, mentor-mentee partnerships, and the formation of self-help groups.

• Journal of Family Resource Management and Policy Review
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• v.14 no.2
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• pp.59-77
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• 2010

This research evaluated the present condition of the family voluntary service group and healthy family campaign, which was being carried out as one of the healthy family culture businesses of the Healthy Family-Support Center. Furthermore, it suggests ways to improve these business activities. Research centered on the analysis of business documents created between December 2006 and November 2007. The results were as follows. First, the family voluntary service group and the healthy family campaign business in the Center must be able to have specificity or individuality. Second, the Center must manage the scale, frequency, and contents of the businesses systematically. Third, the businesses must concern themselves with family life in general, make better use of the advisory committee or steering committee, concern variety of business performing system.

• The Journal of the Korea Contents Association
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• v.11 no.5
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• pp.358-368
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• 2011

The aims of this article are to examine the basic law, contents and concept of counselling work for healthy family and provide the jobs and competency of healthy family supporter for counselling work. The research objects are 48 healthy family supporters for counselling work inclusive of full-time and part-time position. They are analyzed through the survey using questionnaire made by ministry of women and family and headquarter of healthy family support centers. The process of research consists of two parts. One is to suggest their jobs and requirements, the other is to offer their core competency and area for improvement. First, the jobs of healthy family supporters for counselling work are planning, performance and valuation consist of 29 items. A publicity activity of them is the work strengthened strategically. The requirements for the performance of their duties are having a master's degree, career for 3years, and a certificate of qualification of family counselor, healthy family supporters and social worker. Second, their competencies are understanding of the characteristic and life cycle of family, family law, education of family life, ability of documentation, data analysis, sensitivity of the change of family, society and environment, ability of solving the problem, attitude of the dignity of man, positiveness and so on.

• Journal of Families and Better Life
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• v.22 no.5
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• pp.345-355
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• 2004

The purpose of this study is to recommend the roles, Qualification, and fostering system of healthy families specialist. In 2003, 'Organic Law to Develop the healthy Families' was legislated. The law endows the responsibilities and duties of the government, local government, and families, in order to embody the healthy families. Also, this suggests appropriate ways to solve diverse families problems and identifies the necessities of establishing social policies to increase the well-being of family members. The enactment system of this law is to place 'Healthy Families Center' under the Prime Minister, and to foster 'healthy families specialist' who have professional knowledge and skills for strengthen diverse families. The major recommend are as follow. First, the roles of healthy families specialist are a practician, deliverer, and administrator to enact the law's philosophy and ideal. Secondly, to protect the competency of those, the qualification is restricted to university and the same level school graduate people, who majored in Home Economics, Social Work. and Women Studies. Finally. to foster and qualify this specialist. the Council of Healthy Families will be compound.

• The Plant Pathology Journal
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• v.39 no.4
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• pp.397-408
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• 2023

Fire blight disease, caused by Erwinia amylovora, is a devastating affliction in apple cultivation worldwide. Chemical pesticides have exhibited limited effectiveness in controlling the disease, and biological control options for treating fruit trees are limited. Therefore, a relatively large-scale survey is necessary to develop microbial agents for apple trees. Here we collected healthy apple trees from across the country to identify common and core bacterial taxa. We analyzed the endophytic bacterial communities in leaves and twigs and discovered that the twig bacterial communities were more conserved than those in the leaves, regardless of the origin of the sample. This finding indicates that specific endophytic taxa are consistently present in healthy apple trees and may be involved in vital functions such as disease prevention and growth. Furthermore, we compared the community metabolite pathway expression rates of these endophyte communities with those of E. amylovora infected apple trees and discovered that the endophyte communities in healthy apple trees not only had similar community structures but also similar metabolite pathway expression rates. Additionally, Pseudomonas and Methylobacterium-Methylorobrum were the dominant taxa in all healthy apple trees. Our findings provide valuable insights into the potential roles of endophytes in healthy apple trees and inform the development of strategies for enhancing apple growth and resilience. Moreover, the similarity in cluster structure and pathway analysis between healthy orchards was mutually reinforcing, demonstrating the power of microbiome analysis as a tool for identifying factors that contribute to plant health.