• Title/Summary/Keyword: Health research and development

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The lived experience of health-management in patients with Parkinson's disease (파킨슨병 환자의 건강관리 경험)

  • Son, Hye Gyeong;Park, Hyun-Joo;Kim, Sang Jin;Han, A-Leum
    • The Journal of Korean Academic Society of Nursing Education
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    • v.26 no.4
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    • pp.423-433
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    • 2020
  • Purpose: The purpose of this study was to describe the health care experiences among patients with Parkinson's disease. Methods: Of the qualitative research methods, Colaizzi's phenomenological method was used in this study. A total of nine patients, who were diagnosed with Parkinson's disease and receiving outpatient treatment, were selected as the subjects of this study. Subsequently, data were collected through individual in-depth interview. Results: The four categories obtained as a result were 'strenuous efforts to control my own body,' 'subject of health that no one can replace,' 'focus on the current while expecting a breakthrough in health management,' and 'human dignity that cannot be lost to the end.' Conclusion: The study results are expected to help health care providers deeply understand the experiences in health care among patients with Parkinson's disease and to provide source data for nursing intervention development that can be helpful in managing the health status of patients with Parkinson's disease.

A survey of research papers on the health benefits of kimchi and kimchi lactic acid bacteria (김치 및 김치 유래 유산균의 건강 기능성에 대한 연구 동향 조사)

  • Kim, Bohkyung;Mun, Eun-Gyung;Kim, Doyeon;Kim, Young;Park, Yongsoon;Lee, Hae-Jeung;Cha, Youn-Soo
    • Journal of Nutrition and Health
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    • v.51 no.1
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    • pp.1-13
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    • 2018
  • Purpose: This review article provides an overview of the trends of research papers on the health benefits of kimchi and kimchi lactic acid bacteria published from 1995 to 2017. Methods: All publications from 1995 to 2017 regarding kimchi and kimchi lactic acid bacteria were collected, reviewed, and classified. This review article covers the publications of the health benefits of kimchi and kimchi lactic acid bacteria on experimental, clinical trials, and epidemiology studies. Results: The number of publications on kimchi over the period were 590: 385 publications in Korean and 205 publications in English. The number of publications on the health benefits of kimchi and kimchi lactic acid bacteria were 95 in Korean and 54 in English. The number of publications on kimchi and kimchi lactic acid bacteria were 84 and 38, respectively, in the experimental models. Ten research papers on kimchi in clinical trials and 7 publications in epidemiology were found. Kimchi or kimchi lactic acid bacteria had protective effects against oxidative stress, mutagenicity, toxicity, cancer, dyslipidemia, hypertension, immunity, and inflammation in in vitro, cellular, and in vivo animal models. Moreover, kimchi had effects on the serum lipids, intestinal microbiota, iron status, obesity, and metabolic parameters in human clinical trials. In epidemiology, kimchi had effects on hypertension, asthma, atopic dermatitis, rhinitis, cholesterol levels, and free radicals. Conclusion: This review focused on the publications regarding the health benefits of kimchi and kimchi lactic acid bacteria, suggesting the future directions of studies about kimchi and kimchi lactic acid bacteria by producing a database for an evaluation of the health benefits of kimchi.

Review of the Retrospective Drug Utilization Review Program from Foreign Countries' Experience (외국의 후향적 DUR 제도 현황과 정책적 함의)

  • Kim, Dong-Sook;Kim, Su-Kyeong;Jang, Sun-Mee
    • YAKHAK HOEJI
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    • v.55 no.3
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    • pp.173-184
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    • 2011
  • The purpose of this study was to review foreign retrospective Drug Utilization Review(DUR), and so to suggest a development plan suitable for use with domestic situation. Literature review of foreign retrospective DUR program and domestic project such as DUR and prescribing analysis project were reviewed. To improve prescribing quality, developed countries such as US, Canada, UK, France, and Australia have implemented various forms of policy. Based on the review of foreign retrospective DUR program, we suggested to apply practical implementation of retrospective DUR program.

Anti-angiogenesis Activity and Characterization of Extract of Ark Shell Scapharca subcrenata (새꼬막(Scapharca subcrenata) 추출물의 혈관신생 억제활성과 특성)

  • Lim, Chi-Won;Park, Hee-Yeon;Shim, Kil-Bo;Yoon, Na-Young;Kim, Yeon-Kye
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.45 no.4
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    • pp.303-306
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    • 2012
  • Anti-angiogenesis therapy is one of the most promising strategies for the treatment of cancer. We investigated the anti-angiogenesis activity of an extract from the ark shell Scapharca subcrenata and attempted to purify the active compounds. The crude extract of the ark shell inhibited the proliferation of human vein endothelial cells (HUVEC-1) and tube formation by human dermal microvascular endothelial cells (HMEC-1). The methanol extract of the viscera of the ark shell showed activity. The ark shell extract acts as an angiogenesis inhibitor and could be developed further as a health substance, functional food, and anticancer agent.

First Report of Soft Rot by Pectobacterium carotovorum subsp. brasiliense on Amaranth in Korea

  • Jee, Samnyu;Choi, Jang-Gyu;Hong, Suyoung;Lee, Young-Gyu;Kwon, Min
    • Research in Plant Disease
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    • v.24 no.4
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    • pp.339-341
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    • 2018
  • Amaranth has the potential for good materials related to nutrients and health benefits. There are several diseases of amaranth such as leaf blight, damping-off, and root rot. As a causal agent of soft rot disease, Pectobacterium spp. could infect various plant species. In this study, we isolated the bacterial pathogen causing soft rot of amaranth in South Korea. In Gangneung, Gangwon province during 2017, amaranth plants showed typical soft rot symptoms such as wilting, defoliation and odd smell. To isolate pathogen, the macerated tissues of contaminated amaranth were spread onto LB agar plates and purified by a single colony subculture. One ml bacterial suspension of a representative isolate was injected to the stem of five seedlings of 2-week-old amaranth with a needle. Ten mM magnesium sulfate solution was used as a negative control. 16S rDNA gene and recA gene were sequenced and compared with the reference sequences using the BLAST. In the phylogenetic tree based on 16S rDNA gene and recA gene, GSA1 strain was grouped in Pcb.

Current Circumstance and Issues in Traditional Korean Healthcare Sector : What are Public Policy Options for Future Society? (우리나라 한방의료의 현황과 과제 : 미래사회를 위한 정책적 선택)

  • Han, Dong-Woon;Kim, Hyang-Ja;Yoon, Tae-Hyung;Woo, Hye-Kyung
    • Journal of Society of Preventive Korean Medicine
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    • v.9 no.1
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    • pp.77-89
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    • 2005
  • Since 1990's, the Korean society, experiencing the low fertility and aging society, has been confronting with the threats in health care sector. The threats are the increases in the demand for health care, health care financial burden, and so on. In particular, the change of disease pattern and aging population result in the increases patients' demand for not only western medical services but also oriental medical services and complimentary medicine. Recently, the increases in availability of oriental medical services and the health care resources related to oriental medicine are raising some issues and conflicts in the Korean health sector. Theses circumstance required policy makers, central and local government, and public health sector to develop health policies related to oriental medicine and interface or integrate of traditional Korean medicine and Western medicine. For the near future, these issues will probably remain the focus of integration of traditional Korean medicine and Western medicine in public health sector. To cope with the threats in health care sector, one of the opportunities is to scale-up e public role of traditional Korean medical services. The main purpose of this study was to develop strategies to scale-up the Public role of traditional Korean medical services for the future society. The research questions are: what are the trends and problems in traditional Koran medical sector; what are the causes of or associated factors to the problems; how to cope with the problems and how to resolve the cause?; what are the health policy directions and its strategies that the government should take to cope with the future demand and the burden on health care sector? The results of this study are as follows. In order ta scale-up the public role of traditional medicine, this research offered health policy directions for traditional Korean medicine in response to a change environment of health care sector. There are four directions to be addressed: 1) the development of and investment in public oriental medicine infra-structure; 2) the development of public policy on oriental medicine; 3) modernization and globalisation of traditional Korean medicine; 4) the expansion of academic exchange between Western medicine and traditional Korean medicine. Finally, we discussed stakenholders' on traditional Korean medicine in the health care market. Then, public policy options for future society was suggested.

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Development of a nanoparticle multi-generator for assessment of inhalation hazard

  • Lee, Sung-Bae;Han, Jeong-Hee;Kim, Tae-Hyun;Cha, Hyo-Geun;Lim, Cheal-Hong
    • Analytical Science and Technology
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    • v.34 no.2
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    • pp.87-98
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    • 2021
  • In this study, we developed the nanoparticle multi-generator by 3D printer fusion deposition modeling (FDM) method that can reliably generate and deliver nanoparticles at a constant concentration for inhalation risk assessment. A white ABS filament was used as the test material, and SMPS was used for concentration analysis such as particle size and particle distribution. In the case of particle size, the particle size was divided by 100 nm or less and 100 to 1,000 nm, and the number of particles concentration, mass concentration, median diameter of particles, geometric average particle diameter, etc were measured. The occurrence conditions were the extruder temperature, the extruding speed of the nozzle, and the air flow rate, and experiments were conducted according to the change of conditions including the manufacturer's standard conditions. In addition, the utility of inhalation risk assessment was reviewed through a stability maintenance experiment for 6 h. As a result of the experiment, the size of the nanoparticles increased as the discharger temperature increased, as the discharge speed of the nozzle increased, and as the air flow rate decreased. Also, a constant pattern was shown according to the conditions. Even when particles were generated for a long time (6 h), the concentration was kept constant without significant deviation. The distribution of the particles was approximately 80 % for particles of 60 nm to 260 nm, 1.7 % for 1 ㎛ or larger, 0.908 mg/㎥ for the mass concentration, 111 nm for MMAD and 2.10 for GSD. Most of the ABS particles were circular with a size of less than 10 nm, and these circular particles were aggregated to form a cluster of grape with a size of several tens to several hundred nm.

Status of Medical Library Resources and Services in Teaching Hospitals in Enugu State, Nigeria: implications for quality health care services

  • Okeke, Oluchi C.;Eze, Samuel Godwin N;Eze, Jacintha U.;Asogwa, George E.
    • International Journal of Knowledge Content Development & Technology
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    • v.7 no.2
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    • pp.21-40
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    • 2017
  • Considering the need for quality health information and resultant health care services in any society, this study was carried out to look into the status of library and information resources and services provided by medical libraries in Enugu State, Nigeria. The main objective of the study was to find out the information resources and services available for medical library users towards quality health care provision. Five (5) medical libraries of major teaching hospitals were used for the study with 980 registered users as the study population from where 245 users were sampled. Observation checklist was used to collect data on resources while questionnaire was used to collect data from the respondents on the services provided. The Medical Library Association Standard guided the analysis of data from observation while frequency counts and mean scores were used to analyze data from the questionnaire. Major findings showed that even though some of the required resources and services are available and provided the medical libraries, most of the required resources and services are not adequately provided by these libraries.

Analysis of Risk Factors in Children with Suspected Developmental Delays on the Denver Developmental Screening Test

  • Bang, Kyung-Sook
    • Child Health Nursing Research
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    • v.14 no.3
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    • pp.261-268
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    • 2008
  • Purpose: This study was conducted to estimate the prevalence of questionable development according to developmental screening testing for children, and to explore biological and environmental risk factors of developmental delays. Method: The study participants were 153 children under two years of age. A questionnaire and Home Observation for measurement of the Environment (HOME) inventory were used to collect data, and Korean Denver II was administered. Results: The overall prevalence of questionable development was 11.1%. Significant differences in biological factors between the normal development group and questionable development group were the rate of prematurity, twins, the educational level of mother and father's and the presence of an illness in the mother (p<.10). Maternal acceptance in HOME was significantly different between the two groups. The factors related to questionable development that were significant in the logistic regression analysis were prematurity (OR=3.56, p=.026), and maternal acceptance in HOME score (OR=.629, p=.028). Conclusion: Early developmental screening tests seem necessary for all children, especially for prematurely born children. Also, child rearing environments were identified as significant factors in the development of all children. These findings suggest that the HOME scores might be useful in identifying children at risk for developmental delays, and that interventions for these children will probably be more effective if their mothers are helped to provide a more appropriate social environment.

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Identifying research trends in the emergency medical technician field using topic modeling (토픽모델링을 활용한 응급구조사 관련 연구동향)

  • Lee, Jung Eun;Kim, Moo-Hyun
    • The Korean Journal of Emergency Medical Services
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    • v.26 no.2
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    • pp.19-35
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    • 2022
  • Purpose: This study aimed to identify research topics in the emergency medical technician (EMT) field and examine research trends. Methods: In this study, 261 research papers published between January 2000 and May 2022 were collected, and EMT research topics and trends were analyzed using topic modeling techniques. This study used a text mining technique and was conducted using data collection flow, keyword preprocessing, and analysis. Keyword preprocessing and data analysis were done with the RStudio Version 4.0.0 program. Results: Keywords were derived through topic modeling analysis, and eight topics were ultimately identified: patient treatment, various roles, the performance of duties, cardiopulmonary resuscitation, triage systems, job stress, disaster management, and education programs. Conclusion: Based on the research results, it is believed that a study on the development and application of education programs that can successfully increase the emergency care capabilities of EMTs is needed.