• Journal of Mushroom
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• v.22 no.3
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• pp.92-101
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• 2024

Hair dyeing, hair perming, and daily hair dryer use can substantially damage hair. Consequently, the demand for products containing natural ingredients for the care of damaged hair is growing. Although polyphenols with antioxidant effects are often used for hair conditioning, few studies have focused on hair conditioning, and the potential of Sparassis latifolia mushroom extract for hair improvement has not been evaluated to date. In this study, the antioxidant activity of and polyphenol content in hot water, 70% and 100% ethanol (EtOH), n-hexane, ethyl acetate (EtOAc), and water extracts of S. latifolia were analyzed. A hair treatment containing S. latifolia extract was prepared, and its effect on damaged hair was evaluated. The highest antioxidant activity was observed in the hot water and EtOAc extracts. Moreover, polyphenol analysis using high-performance liquid chromatography and liquid chromatography-mass spectroscopy confirmed that the EtOAc fraction has relatively high contents of specific polyphenols beneficial for hair. Based on these results, a hair treatment containing S. latifolia extract was applied to damaged hair, and hair improvement was evaluated using hair thickness, tensile strength, and scanning electron microscopy. The hair treatment containing 70% EtOH extract effectively improved hair condition. We postulate that this improvement was caused by the high hydrophobic polyphenol content in the 70% EtOH extract.

• BMB Reports
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• v.55 no.11
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• pp.559-564
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• 2022

Diabetes mellitus is one of the most prevalent diseases in modern society. Many complicationssuch as hepatic cirrhosis, neuropathy, cardiac infarction, and so on are associated with diabetes. Although a relationship between diabetes and hair loss has been recently reported, the treatment of diabetic hair loss by Wnt/β-catenin activators has not been achieved yet. In this study, we found that the depilation-induced anagen phase was delayed in both db/db mice and high-fat diet (HFD) and streptozotocin (STZ)-induced diabetic mice. In diabetic mice, both hair regrowth and wound-induced hair follicle neogenesis (WIHN) were reduced because of suppression of Wnt/β-catenin signaling and decreased proliferation of hair follicle cells. We identified that KY19382, a small molecule that activates Wnt/β-catenin signaling, restored the capabilities of regrowth and WIHN in diabetic mice. The Wnt/β-catenin signaling activator also increased the length of the human hair follicle which was decreased under high glucose culture conditions. Overall, the diabetic condition reduced both hair regrowth and regeneration with suppression of the Wnt/β-catenin signaling pathway. Consequently, the usage of Wnt/β-catenin signaling activators could be a potential strategy to treat diabetes-induced alopecia patients.

• The Korean Journal of Food And Nutrition
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• v.12 no.6
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• pp.588-591
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• 1999

현대여성들은 모발상태에 관심이 많으나 정확한 모발분석을 해주는 곳도 드물고 자신의 모발상태에 관한 상담이나 지식을 전달받을 곳도 많지않은 실정이다. 따라서 본 연구는 1999년 10월 2일부터 -10월 6일까지 청주시내 거주하는 여학생을 대상으로 모발의 자가진단과 모발관리방법 모발에 대한 무제점 등을 파악하고 올바른 모발관리 습관을 갖는데 도움이 되고자 실시되었다. 본 연구 결과는 다음과 같다. 1. 연구대상자의 일반적 특성은 연령별 분포는 18세 -20세가 65,9% 21-30세가 30.9% 31세이상이 3,4%였다 2. 대상자들ㅇ의 모발상태는 손상모가 51.9%였으며 건강모가 21.6%로 손상모의 비율이 높았다. 3. 모발손상의 원인은 염색·탈색·퍼머의 시술이 47.1%로 가장높았고 드라이의 비율이 22.3%였다. 4. 모발이 자라는 정도는 잘 자란다가56,7%였다. 5., 현재 모발에 대한 가장 큰 관심거리는 머리결로 나타났고 헤어스타일도 높은 비중을 차지하였다. 6. 모발의 손질 횟수는 1주일에 한번이 32,3%로 가장 일반적이었고 대상자들의 33%는 모발손질을 전혀하지 않았다. 7. 모발의 손상도가 높을수록 모발관리벙법이나 횟수와 유의한 관련성이 있었다(P<0.05) 모발의 손상도가 심할수록 모발관리에 관심을 가졌고 모발관리 횟소도 많았다

• Korean Journal of Clinical Pharmacy
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• v.21 no.3
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• pp.256-269
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• 2011

Omega-3 fatty acids are a specific type of unsaturated fat that the body cannot manufacture on its own, so they must be obtained from food which is essential fatty acids (EFAs). Omega-3 fatty acids consist of three types which are a-Linolenic Acid (ALA), Eicosapentaenoic (ELA), and Docosahexaenoic Acid (DHA). Especially, EFAs help to prevent skin and hair drying, acne, eczema, prevention from allergies, brittle nails, rashes, and tiny lumps. The aim of this study is to investigate improvement and protection for hair damaged by chemical treatment with omega-3 formulated shampoo. We selected virgin hair sample and divided into two groups for bleaching once and three times and then damaged hair by changing the number of hair bleaching (twice with interval of 15 minutes). Each bleached hair was treated by five different kinds of shampoo (Control, Horse shampoo, DHA shampoo, EPA shampoo, Omega-3 shampoo mixture). Apart from this, EPA/DHA 2, 5, 8, 10 and 12% shampoo were prepared and treated to hair for comparing rate of progress in damaged hair. To quantify improved condition of damaged hair, we performed Scanning Electron Microscope (SEM) for ultrastructure of damaged hair fraction, measurement of thickness change and BCA Protein Assay for recovery rate of damaged hair. The moisture in hair was measured by Thermal analysis machine. In results, we observed the particle of hair surface damaged by bleaching treatment were well improved with treatment with EPA and DHA shampoo. Also, quantity of protein was lowered with higher concentration of EPA & DHA i.e., 8 and 12 % then compared with horse oil shampoo in three times treatment group. It shows that bleached hair have been recovered by treating rapidly and get protective coat. In conclusion, EPA and DHA shampoo improved damaged hair, especially with EPA / DHA 12% shampoo. Also, EPA shampoo could protect the damaged hair depending on increasing concentration of EPA. Therefore, we conclude omega-3 shampoo could make damaged hair protect and get healthy hair environment.

• Applied Microscopy
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• v.35 no.4
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• pp.24-31
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• 2005

The preservative condition and ultrastructure on the mummified hair collected from newly found female mummy in Paju, were investigated by using scanning and transmission electron microscopes. The female mummy was found in september, 2002 during the traditional reburial process for the buried ones. The hair of 16th century mummy showed very intact appearances during observation with electron microscope. And the structures of the cortex, medulla and cuticle were well preserved. The cuticle layer was easily discernable, which are composed of six to seven cuticular cells. Each cuticular cells surrounded and thus seperated from its neighbors by intercellular membrane complex. In the cortex, many macrofibrils and some melanin granules between them were observed. We observed well preserved rod form macrofibrils running parallel along the direction of hair shaft. Especially, melanin granules were aggregated in the cortex which was adjacent to the cuticlu layer. As to the cause for the well-preservation of 440 year old hair sample, the presence of surface coat on the hair, which are composed of various materials. As calcium was included in the surface coat in Electron Dispersive X-ray Spectroscopy (EDS), the hardening process of the surface coat by calcium might inhibit the water or microorganism infiltration into the hair.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.7 s.250
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• pp.773-778
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• 2006

High-aspect-ratio nano-hair or nano-pillar arrays have great potential in a variety of applications. In this study, we present a simple and cost-effective replication method of high-aspect-ratio polymer nano-hair arrays. Highly ordered nano-porous AAO (anodic aluminum oxide) template was utilized as a reusable nano-mold insert. The AAO nano-mold insert fabricated by the two-step anodization process in this study had close- packed straight nano-pores, which enabled us to replicate densely arranged nano-hairs. The diameter, depth and pore spacing of the nano-pores in the fabricated AAO nano-mold insert were about 200nm, $1{\mu}m$ and 450nm, respectively. For the replication of polymer nano-hair arrays, a UV nano embossing process was applied as a mass production method. The UV nano embossing machine was developed by our group for the purpose of replicating nano-structures by means of non-transparent nano-mold inserts. Densely arranged high-aspect-ratio nano-hair arrays have been successfully manufactured by means of the UV nano embossing process with the AAO nano-mold insert under the optimum processing condition.

• Journal of Veterinary Clinics
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• v.32 no.6
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• pp.527-529
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• 2015

A 7 year-old intact female black spotted and white hair Shih-tzu dog visited for screening of vital condition and was suspected multifocal alopecia on physical examination. On dermatologic examination, alopecia with patches on black spot area, generalized seborrhea sicca, and bacterial infection were detected. Additionally, melanin clumping in the hair shafts on the alopecic area was detected by microscopic examination. Based on the signalment and dermatologic examination, black hair follicular dysplasia was diagnosed. To our best knowledge, this the first case report of black hair follicular dysplasia in Shih-tzu.

• Journal of Fashion Business
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• v.7 no.1
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• pp.116-134
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• 2003

The beauty industry of today tends to gradually develope as one of the important marketing strategies along with the total fashion sector. Hair color, being one of the factors of hair style, especially builds his or her own image and even becomes the nonverbal communication method which let others know him/herself. Therefore, women's needs and expectations of hair coloring are varied. To meet these need, it is urgent to figure out, most of all, the status of customers' awareness about hair coloring. Thus, in this study, research and analysis on hair coloring were made, focusing on the women utilizing 20 beauty shops in Changwon city. And the goal that this study set is to use as the study material for the hair coloring consulting in the beauty industry and the basic data for marketing in the industry job-sites. The conclusion by the three factors(age, job, monthly income) were as follows: 1. Dandyism was on the 1st order in the reason for coloring hair regardless of age, job, and monthly income. This seems to be speaking for the change of women's awareness of coloring hair. 2. The subject of making decision upon whether she was going to color her hair or not was herself regardless of age, job, and monthly income. Among the people belong to these three factors, brown was the color in overall preference. 3. More than half of those who belong to the three factors were not aware of the hair color, but their senses and interest in the color in vogue were high. 4. In terms of the hair coloring periodic time, many people had $2{\sim}3$months, but it was possible to know that they were interested in improving their images, considering the fact that most of the salaried people had their hair dyed within a month and the people in service job over a month. 5. The acquaintance around me had the strongest effect in collecting information from the people in those three factors and mass media was the next. The results of this study, in my opinion, would help the customers have beautiful and healthy hair and make images of their own by making the hair designers develope professional knowledges and skills on the hair coloring and improve the quality of beauty services.

• The Journal of Internal Korean Medicine
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• v.38 no.2
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• pp.235-239
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• 2017

This case study describes the effect of Bojungikki-tang on chemotherapy-induced alopecia. Alopecia is a well-documented cause of distress to patients undergoing cancer treatment, but no approved pharmacological treatment exists for chemotherapy-induced hair loss. A 70-year-old female diagnosed with a cholangiocarcinoma and liver metastasis received chemotherapy, including gemcitabine and cisplatin, every three weeks. As a result of the continuous chemotherapy, she suffered various toxicity-related side effects, including bone marrow suppression, general weakness, nausea, peripheral numbness, and hair loss. Bojungikki-tang was initially administered to improve the patient's general weakness and fatigue. After three months of treatment, the patient's hair loss and general condition improved, and the color of the new hair was dark, despite the chemotherapy. The treatment did not improve other symptoms, such as bone marrow suppression and peripheral numbness. This case suggests that Bojungikki-tang could have a beneficial effect on chemotherapy-induced alopecia.

• The Journal of Pediatrics of Korean Medicine
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• v.26 no.2
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• pp.47-52
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• 2012

Objectives The purpose of this study is to know the effect of Baekhogainsam-Tang on alopecia areata. Methods We decided the treatment principle through abdominal examinations and symptoms. We used herbal medicine (Baekhogainsam-Tang) to increase the roots of hair and hair. Results After the treatment, patients' hair condition had been improved (Hair loss patch diameter decreased from 2.5 cm to 0.5 cm). In addition, patient's physical symptoms were improved. Conclusions This case shows that herbal medicine, which focused on patient's physical symptom, is seemed to be effective in alopecia areata.