• Journal of the Society of Cosmetic Scientists of Korea
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• v.36 no.3
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• pp.215-219
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• 2010

In this study, we investigated effects of Monegy (mixture of Sophorae Radix, Panax ginseng, Salvia miltiorrhiza BUNGE) on epilate-induced hair-loss in dorsal region of C57/BL6 mice and external structure of human hair. For morphological and histological analysis in scalp of epilate-induced hair-loss animal model, we utilized several microscopic techniques, such as confocal laser scanning microscopy (CLSM) and LAS 4000. Confocal analysis showed the distribution of FITC-conjugated Monegy and penetration depth compared with normal and control group. Furthermore, when Monegy was topically administrated onto a C57BL6 mouse, it penetrated very well. The fluorescence intensity was increased upto 205 and 113 folds compared to normal and control group, respectively. Also, area of fluorescence was increased to upto 255 to 127 folds compared to normal and control group. Broad scale area of fluorescence in dermis region was observed in the Monegy-treated mice. Furthermore, Monegy induced upto 75% hair repair against depilation. It might be promoted via the induction of growth factors in hair follicle.

• Analytical Science and Technology
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• v.24 no.1
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• pp.1-9
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• 2011

We described an estimation of measurement uncertainty in quantitative analysis of 11-nor-9-carboxy-${\Delta}^9$-tetrahydrocannabinol (THC-COOH), the metabolite of ${\Delta}^9$-tetrahydrocannabinol, in hair samples by using the bead-assisted liquid-liquid extraction and gas chromatography-tandem mass spectrometric (GC-NCI-MS/MS) detection. Traceability of measurement was established through the use of reference materials, calibrated volumetric tubes, volume measuring devices, and measuring instruments. The analytical results were compared and the different contributions to the uncertainty were evaluated. Inter-day variation was performed by using statistical analysis of several indicative factors. Measurement uncertainty associated with the analyte in real forensic hair samples were estimated using QC data. The major factor of contribution to combined standard uncertainty was inter-day repeatability, while those associated with preparation of analytical standard and also sample of weight were insignificant considering the degree of contribution. Relative uncertainty of relative extended standard uncertainty divided into the measured concentration of the analyte was 17% in a hair sample. The uncertainty of result evaluation will be invaluable to improve quality of the analysis.

• Food Science of Animal Resources
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• v.28 no.2
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• pp.222-231
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• 2008

This study was carried out to develop a method for decreasing the heavy metal composition of living stock. Sprague-Dawley (SD) male rats were pre-treated with heavy metals administered i.p. at the limits of regulation according to the feed CODEX in Korea. Herbal medicine remnant was administered p.o. (2, 4 ppm of average feeding amount) for the entire period of study with organic selenium (2 ppm of average feeding amount) before any other treatment. 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) was also administered i.p. in a single dose of 60 mg/kg body weight before animals were sacrificed. The TBARS test with the FOX assay demonstrates a decrease of heavy metals due to these functional materials in vitro. Moreover, this decrease in heavy metals was also demonstrated by in vivo tests based on SD rats hair analysis and organ analysis after 6 weeks. A good linear correlation between hair analysis and organ analysis represented by liver and blood was shown. The present findings suggest that measurement method of heavy metal composition using hair analysis for healthy livestock can be used in place of detection methods carried out by organ and blood analysis, and herbal medicines with organic selenium may be very effective at decreasing heavy metals of feed materials in feed manufacture industry.

• Journal of Korean Home Economics Education Association
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• v.23 no.2
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• pp.1-16
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• 2011

This study investigates the relationship between the purchasing behavior for hair-care products and the attitude toward hair-care products by adolescents. A total of 412 middle and high school students located in Seoul and Gyunggi-do province participated in this research. SPSS 12.0 for Windows Program was utilized for statistical analysis. As a result, the hair concerns and the satisfaction of adolescents as well as their attitudes towards hair-care products were significantly affected by gender, school level, and educational experiences. Female high school students with some degree of educational experiences had a more rational and brand-oriented attitude. Students having a higher rational and brand-oriented attitude bought hair-care products in regards to the quality of the product and environmental impact. On the other hand, those having a conspicuous and fashion pursuit attitude showed an image and fashion concern purchasing behavior. Adolescents usually purchased styling and dyeing products at a cosmetic specialty store and hair-care cleaning products from a discount store. They obtained the information about hair-care products from relatives, personal experiences, and TV advertisements.

• Applied Chemistry for Engineering
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• v.32 no.6
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• pp.647-652
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• 2021

In this study, Saussurea Lappa roots were extracted using ethanol and n-hexane, and also the effects on proliferation of human hair dermal papilla cells and fibroblast and related signaling pathway were evaluated. 3-[4, 5-dimethylthiazol-2-yl]-2, 5 diphenyl tetrazolium bromide (MTT) assay was conducted for cell proliferation effect of Saussurea Lappa root extract, and extracellular signal-related kinase (ERK), serine/threonine protein kinase (Akt), wingless-related integration site (Wnt)/𝛽-catenin signaling pathway, and 5𝛼-reductase expression through western blot analysis were measured. Saussurea Lappa root extract significantly increased human hair dermal papilla cells and propagation of fibroblast, promoted phosphorylation of ERK and Akt that get involved in cell proliferation. Additionally, Saussurea Lappa root extract significantly decreased promotion of Akt phosphorylation and cell proliferation by MEK/ERK inhibitor PD98059 and PI3K/Akt inhibitor LY294002. Also, Saussurea Lappa root extract induced intranuclear 𝛽-catenin accumulation by promoting phosphorylation of 𝛽-catenin (Ser552, 675) through phosphorylation of GSK-3𝛽 (Ser9), and suppressed activation of 5𝛼-reductase type I and II. Overall, Saussurea Lappa root induces cell proliferation through vitalization of ERK and Akt route of human hair dermal papilla cells and fibroblast and apoptosis defense mechanism, and can be helpful in hair loss prevention and hair growth by vitalizing the 𝛽-catenin signaling pathway and inhibiting activation of 5𝛼-reductase, which can be used as a potential hair care products.

• Journal of the Korean Applied Science and Technology
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• v.38 no.4
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• pp.986-993
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• 2021

This study was aimed to investigate the improvement effects of kelp extract on the damaged hair by manufacturing hair quality improving formulation adding kelp extract and applying that in the damaged hair. With respect to the study materials, the formulation was manufactured with different strengths of kelp extract including 0, 2, 4, and 6 grams, adding perm base material. The manufactured formulation was applied to the decolored sample hair of Level 8 and its effects were measured and compared before and after its application. Tensile strength, absorbance using methylene blue, and gloss were measured as the tools to show the improvement effects of hair quality. To check the reliability of the results, statistical analysis was performed. Tensile strength showed to be increased in the Level 8 samples applied by the formulations containing 4- and 6-gram strength. Absorbance using methylene blue showed to be decreased in all the samples after the application, based on the absorbance results before and after the application. No difference was found in all the samples on the gloss. In conclusion, this study revealed that kelp extract could improve the damaged hair. Further studies are required to check the improvement effects on the damaged hair with multiple types of extracts and study methods.

• Journal of the Korean Applied Science and Technology
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• v.38 no.3
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• pp.700-707
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• 2021

This study aimed to understand the effects of apricot kernel oil on the improvement of hair texture by producing a hair texture improvement agent added with apricot kernel oil and then applying it to damaged hair. In the test method and measurement, the agent was produced by putting different contents of apricot kernel oil like 0 g, 1 g 2 g, and 3 g. After applying the produced agent to bleached sample hair, it was heat treated and then left as it was. The comparative analysis was conducted by measuring each sample before and after application. To understand its effects on the improvement of hair texture, the tensile strength, absorbance with the use of methylene blue, and gloss were measured. In the results of this study, the tensile strength was increased in every sample except for healthy hair after application. In the results of analyzing the absorbance with the use of methylene blue, it was decreased in samples like 7L(1), 7L(2), 7L(3), and 9L(3) after application. In the results of measuring the gloss, it was increased in the samples like 7L(1), 7L(2), 7L(3), and 9L(3). Such changes in the tensile strength, absorbance, and gloss showed the effects of apricot kernel oil on the texture improvement of damaged hair. In the future, it would be necessary to have researches on various methods of measurement and treatment.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.46 no.3
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• pp.295-305
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• 2020

Treatment for beauty using oxidizing agents damages hair with inducing structural alteration in cuticle layer, degradation of protein, and loss of lipid. This study connects a frictional coefficient upon the damaged hair by an instrumental test to the texture test by human being, and considered a moisture as a factor of the damage. A friction coefficient has been measured upon the hair with successive treatment of dye, perm, and bleach. The friction coefficient from the hair dye-treated three times was defined with 0.60, where 58% of answerer indicated an initial damage point as the hairs of iteration of dye-treatment increased. Even bleach treated three times results in 0.84 of friction coefficient corresponding to 88% of answerer attributed the hair to an initially damaged hair. In order to figure out a lipid loss in hair for human being to respond damage, a friction coefficient of the hair was controlled by removing 18-methyleicosanoic acid (18-MEA). The initial damage has been recognized by 0.60 of the friction coefficient for the 68% of answerer. Since moisture is the largest portion of the components in hair, moisture analysis has been performed to study a relationship between texture of damage and the friction coefficient from an instrumental evaluation. As an iteration of dye increases, the hair became hydrophilic with smaller contact angle. It is found that a damaged hair by dyeing possessed more than 0.42% of moisture compared to a healthy hair. Finally, it is elucidated that an increase of moisture in hair induced higher adhesive force corresponding to the friction coefficient, and the friction coefficient above 0.6 is attributed to the preception of hair damage.

• The Korean Journal of Applied Statistics
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• v.17 no.2
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• pp.197-204
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• 2004

We have sent the 1000 hair samples to USA and received the results from USA because the programs for the interpretation of Tissue Mineral Analysis (TMA) result is not opened yet in Korea. Therefore, the study will analyze the relationship between the hair for Korean and minerals and make a classification system. To achieve the goal, first of all, we coded the results of patients and classified the analyzed results which are the interrelationship between the minerals and dietary situation and the heavy metals and diseases through the statistical methods. Finally we classified 8 metabolic type using decision tree classifier.

• Journal of the Korean Home Economics Association
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• v.43 no.6 s.208
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• pp.97-112
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• 2005

The purpose of this study was to examine how female college students' physical characteristics affect their and hairstyle behavior. The study methodology was a survey, with questions gathered from the previous research surveys and collated by the author. The study subjects 350 female college students in Gwangju, Korea. This survey was performed from November 8thto 13th 2004, and 348 questionnaires were finally used for the study analysis.. The research results are summarized as follows: 1. As a result of the analysis on the research variants, costume behavior was derived from four factors clothing sympathy, clothing exhibition, clothing convenience, clothing aesthetics. Hairstyle behavior was derived from five factors: hair sympathy, hair individuality, hair aesthetics, dependency on hair designer, and hair convenience. 2. The difference between clothing and hairstyle behavior according to physical characteristics showed that clothing and hairstyle behavior make a significant difference according to the height, weight, study major, spending money, and family income. 3. There was a positive correlation among clothing and hairstyle behavior clothing Female college students showed the same differences in clothing behavior as in hairstyle behavior according to their own physical characteristics. When more satisfied with their body shape, they tended to pursue a clothing aesthetic. When more dissatisfied with their body shape, they tended to pursue a comfortable and acceptable look, which does not attract others' attention, rather than pee the changes of hairstyle and fashion.