• Journal of Korean Neurosurgical Society
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• v.61 no.4
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• pp.485-493
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• 2018

Objective : Cerebral varices (CVs) without an arteriovenous shunt, so called nonfistulous CVs, are very rare, and their etiology and natural course are not well understood. The aim of this study is to evaluate the clinical outcomes of nonfistulous CVs by the analysis of 39 cases. Methods : From 2000 to 2015, 22 patients with 39 nonfistulous CVs (${\geq}5mm$) were found by searching the medical and radiologic records of our institute. Clinical data and radiological data including numbers, sizes and locations of CVs and associated anomalies were retrospectively collected and analyzed. Previously reported cases in literature were reviewed as well. Results : The mean age of the patients was 21 years (range, 0-78 years). On average, $1.8{\pm}1.2CVs$ were found per patient. CVs were categorized as either fusiform or saccular depending on their shapes. Two patients had saccular type CVs, seventeen patients had fusiform types, and three patients had both fusiform and saccular CVs. Eight patients had associated compromise of the vein of Galen and the straight sinus. Four of those patients had sinus pericranii, as well. Five patients had CVs that were distal draining veins of large developmental venous anomalies. One patient had associated migration anomaly, and two patients had Sturge-Weber syndrome. Six patients with an isolated cerebral varix were observed. Of the 39 CVs in 22 patients, 20 lesions in 14 patients were followed up in outpatient clinics with imaging studies. The average follow-up duration was 6.6 years. During this period, no neurological events occurred, and all the lesions were managed conservatively. Conclusion : Nonfistulous CVs seemed to be asymptomatic in most cases and remained clinically silent. Hence, we suggest conservative management.

• Journal of Digital Convergence
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• v.16 no.2
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• pp.225-234
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• 2018

The purpose of this study was to examine relationships among drinking motives, acculturative stress and problem drinking, and then to identify the influencing factors of problem drinking in foreign workers. A total of 120 foreign workers recruited from two shipyards in G city. Self-reported questionnaire survey was conducted from October to December, 2016. As a result, a rate of problem drinking in foreign workers was 39.2%. According to the multiple regression analysis, their problem drinking was significantly influenced by social motives (${\beta}=.368$ p=.003) and conformity motives (${\beta}=.337$ p=.005) as a subscale of drinking motives and homesickness (${\beta}=-.197$, p=.009) as a subscale of acculturative stress, explained 39.5% of the total variance (F=26.849, p=.000). Based on our results, an education program using drinking motives, acculturative stress should be developed to prevent problem drinking in foreign workers.

• The Korea Journal of Herbology
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• v.39 no.1
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• pp.39-47
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• 2024

Objectives : This study evaluates how various traditional Korean herbal medicines assess MUC5AC expression for esophageal mucosal defense and analyzes the associated mechanisms involved in inflammation. Methods : Forty types of traditional Korean herbal medicines were assessed for in vitro antioxidant activities, and the real-time PCR method was employed to analyze MUC5AC expression under pH 4.5 conditions in human esophageal epithelial cells (HET-1A). Eight types of Korean herbal medicines were evaluated for in vitro antioxidant activities, and Reactive oxygen specise (ROS) expression was analyzed under bile salt (480 𝜇M) and pH 5.5 conditions in human esophageal epithelial cells (HET-1A). Simulation experiments involving bile salts and acidity were conducted for one hour to assess the efficacy of four drugs, and the activities of Mitogen-activated Protein Kinase (MEK), Nuclear Factor Kappa B (NF-𝜅B), and Cyclooxygenase-2 (COX-2) were detected through Western blot analysis. Results : Compared to the Normal group, the Control group exhibited higher ROS generation. Such increased ROS levels were significantly reduced by four extracts: Citrus Unshius Pericarpium (CUP), Cnidium officinale Rhizoma (CR), Ginseng Radix (GR), and Linderae Radix (LR). The protein expression of COX-2 decreased with the treatment of LR, CUP, and CR. Particularly, CUP and CR exhibited superior effects compared to other groups in inhibiting the phosphorylation of NF-𝜅B. Conclusion : Based on the results obtained, we have identified drugs that inhibit oxidative stress and inflammation caused by bile acid in esophageal epithelial cells. Our future plans involve comparing and analyzing the efficacy of these herbal medicines through animal experiments.

• Journal of Korean Society of Forest Science
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• v.103 no.3
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• pp.422-430
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• 2014

This study was conducted to investigate growth changes of DBH, height, crown width, volume, stem biomass, and dead trees after thinning treatments with different thinning intensity for Korean white pine (Pinus koraiensis) plantation. First thinning was applied with 29~69% intensity based on number of trees in 19-yearold plantation, and trees were measured three times: right after thinning (19-year-old), 5 years later (24-yearold), 12 years later (29-year-old). In the case of DBH growth, average DBH growth of heavily thinned plots was 19.6~19.9% higher 5 years later, and 13.3~24.7% higher 12 years later, compared to that of unthinned plots. Initial diameter growth rate was higher than late growth rate. The proportion of large pole candidates ($DBH{\geq}25cm$) was 31% in heavily thinned plot while only 2% was shown in unthinned plot. No difference was shown in height growth depending on plots, and average crown width growth in heavily thinned plots was 30.6~33.3% higher, 5 years later, and 35.0~40.0% higher, 12 years later, compared to that of unthinned plots. Average volume growth of individual trees in heavily thinned plots was 39.8~46.8% higher, 5 years later, and 23.0~52.0% higher, 12 years later, compared to unthinned plots. The maximum volume and biomass per unit area were shown in unthinned plot; the volume and biomass 5 and 12 years later after thinning were $133m^3/ha$ (51 kg/ha) and $344m^3/ha$ (132 kg/ha), respectivily. The significant difference appeared in crown width, volume, and biomass depending on thinning intensity. No dead trees occurred in heavily thinned plots for 12 years after thinning, while mortality rate in unthinned plots was 27.9~37.8%. As a result of analyzing annual increment using cores to determine the timing of second thinning, it suggested that second thinning be suitable around 10 years after first thinning.

• Journal of the Korean Association of Geographic Information Studies
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• v.17 no.4
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• pp.69-85
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• 2014

Carbon stocks of NFI plots can be accurately estimated using field survey information. However, an accurate estimation of carbon stocks in other unsurveyed sites is very difficult. In order to fill this gap, various spatial information can be used as an ancillary data. In South Korea, there is the 1:5,000 forest type map that was produced by digital air-photo interpretation and field survey. Because this map contains very detailed forest information, it can be used as the high-quality spatial data for estimating carbon stocks. In this study, we compared three upscaling methods based on the 1:5,000 forest type map and 5th national forest inventory data. Map algebra(method 1), RK(Regression Kriging)(method 2), and GWR(Geographically Weighted Regression)(method 3) were applied to estimate forest carbon stock in Chungcheong-nam Do and Daejeon metropolitan city. The range of carbon stocks from method 2(1.39~138.80 tonC/ha) and method 3(1.28~149.98 tonC/ha) were more similar to that of previous method(1.56~156.40 tonC/ha) than that of method 1(0.00~93.37 tonC/ha). This result shows that RK and GWR considering spatial autocorrelation can show spatial heterogeneity of carbon stocks. We carried out paired t-test for carbon stock data using 186 sample points to assess estimation accuracy. As a result, the average carbon stocks of method 2 and field survey method were not significantly different at p=0.05 using paired t-test. And the result of method 2 showed the lowest RMSE. Therefore regression kriging method is useful to consider spatial variations of carbon stocks distribution in rugged terrain and complex forest stand.

• Korean Journal of Ecology and Environment
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• v.47 no.4
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• pp.319-327
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• 2014

Understanding and quantifying of carbon storage in ecosystem is very important factor for predicting change of global carbon cycle under the global climate change. We estimated total ecosystem carbon in Gyeryongsan National Park with naturally well preserved ecosystem in Korea. Vegetation of Gyeryongsan National Park was classified with mainly four communities with Quercus mongolica (1,743.5 ha, 38.0%), Quercus variabilis (1,174.0 ha, 25.6%), Quercus serrata (971.9 ha, 21.2%), Pinus densiflora (695.2 ha, 15.2%). Biomass and soil carbons were calculated from biomass allometric equations based on the DBH and carbon contents of soil and litter collected in quadrat in each community. The tree biomass carbon was in Quercus variabilis ($130.1tCha^{-1}$), Pinus densiflora ($111.1tCha^{-1}$), Quercus mongolica ($76.2tCha^{-1}$), Quercus serrata ($39.0tCha^{-1}$). Soil carbon storage was in Quercus mongolica ($159.7tCha^{-1}$), Quercus serrata ($121.0tCha^{-1}$), Pinus densiflora ($110.5tCha^{-1}$), Quercus variabilis ($90.8tCha^{-1}$). Ecosystem carbon storage was Pinus densiflora ($239.9tCha^{-1}$), Quercus mongolica ($235.9tCha^{-1}$), Quercus variabilis ($226.0tCha^{-1}$), Quercus serrata ($165.9tCha^{-1}$), total amount was $867.7tCha^{-1}$. The area of each vegetation carbon storage was Quercus mongolica ($411,200tCha^{-1}$), Quercus variabilis ($265,300tCha^{-1}$), Pinus densiflora ($166,800tCha^{-1}$), Quercus serrata ($161,200tCha^{-1}$) and the total ecosystem carbon amount estimated $1,045,400tCha^{-1}$ at Gyeryongsan National Park. Theses results indicate that different in naturally well preserved ecosystem.

• Journal of The Korean Society of Grassland and Forage Science
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• v.36 no.2
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• pp.109-114
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• 2016

This study was conducted to determine grazing intensity of growing Korean native goats (Capra hircus coreanae) on mountainous pasture. It was carried out to obtain basic information for improvement of mountainous pasture management and establishing feeding system of Korean native goats. Castrated, male goats (n=10) with average initial body weight (BW) of $23.33{\pm}2.15kg$ and an average age of 4 months were used in this study. Grazing goats were supplemented by concentrates with 1.0% of BW. The crude protein content of forage was the highest in October ($22.71{\pm}0.25%$) and there were significantly differences (p<0.05) in monthly comparison. The forage productivity of pasture was the highest from May to June ($1718.7{\pm}207.5{\sim}1672.0{\pm}422.8kg/ha$ but it was decreased in July ($1356.0{\pm}103.8kg/ha$) because of drought and summer depression. Average daily gains (ADG) of goats were the highest in June ($99.5{\pm}6.4d/g$). Grazing intensity was calculated by forage productivity and dry matter intake (DMI) and was the highest in May (65 head/ha). As shown in the results of this research, grazing intensity was suggested to average 39 head/ha from May to October. It is desirable that adequate grazing intensity was maintained by adjusting supplemental feed.

• Journal of The Korean Society of Grassland and Forage Science
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• v.39 no.1
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• pp.45-52
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• 2019

This experiment was carried out to study the change of productivity and feed value in different types of hilly pasture. The pasture utilized in the experiment was placed on the experimental farm of Pyeongchang Campus of Seoul National University. Forage production type(FP; Orchardgrass 18 + Tall Fescue 12 + Timothy 5 + White clover 5 kg/ha) and Public farm type(PF: Orchardgrass 12 + Tall Fescue 18 + Timothy 5 + White clover 5 kg/ha) pasture were established in September 3, 2014 and utilized (cutting or grazing) four times every year. Growth characteristics, yield and forage quality were investigated for two years. Plant height of grasses was the highest in the $1^{st}$ cutting and legumes was in the $2^{nd}$ cutting. Dry matter (DM) content was highest at every the $1^{st}$ cut grasses significantly lower at the $2^{nd}$ harvest (p<0.05). However, there was no significant difference in the $2^{nd}$, $3^{rd}$ and $4^{th}$ harvest in 2016. In the botanical composition change, the portion of legume was gradually increased after pasture establishment and the ratio of weed and bare land was higher at $2^{nd}$ and $3^{rd}$ cutting, but it was decreased at $4^{th}$ harvest. There was no significant difference in 2016 of fresh yield between two farm types (p>0.05). The yield of dry matter showed similar trend of fresh yield and forage production type was higher than that of public farm type (p<0.05). The forage intake by livestock was 1,452 kg/ha in 2015 and 1,743 kg/ha in 2016. Pasture utilization ratio of public farm type pasture was highest in the $3^{rd}$ grazing time. Forage quality of pasture in relation to management type had not significant difference, but there was difference in harvest times. Crude protein (CP) was the lowest in the $1^{st}$ harvest and total digestible nutrient (TDN) was highest in the $1^{st}$ harvest and lowest in the $4^{th}$ harvest. Based on the above results, it is found that the establishment of pasture suitable for farm's situation is important for set up of Korean model of hilly pasture. Although the forage production type is superior on forage productivity, it is recommended that the results will be provided as basic data for management of public farm type in the future.

• Journal of The Korean Society of Grassland and Forage Science
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• v.39 no.1
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• pp.24-30
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• 2019

This study was conducted to investigate the effect of seeding dates on grassland productivity and botanical composition in oversown pasture located in Cheonan of South Korea. Four treatment groups were established based on the seeding dates: 18th August, 1st September, 15th September and 29th September. Evaluation of seasonal changes in botanical composition of pasture showed that the highest ratios of grass in 18th August and 1st September (pasture species 93% and weeds 7%) and the lowest in 15th September (pasture species 75% and weeds 25%). In the plant length, there is no significantly different in 5% probability level. In the total dry matter yield of grass, 18th August ($13,362kg\;ha^{-1}$) and 1st September ($13,988kg\;ha^{-1}$) were higher than 15th September ($11,883kg\;ha^{-1}$) and 29th September ($11,459kg\;ha^{-1}$). The findings of the this study suggest that seeding by early September the most desirable results for botanical composition and grassland productivity in oversown pasture, Cheonan of South Korea.

• Microbiology and Biotechnology Letters
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• v.48 no.4
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• pp.525-532
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• 2020

A continuous fermentation process was carried out to enhance hyaluronic acid (HA) production using Streptococcus zooepidemicus cells. During the 1st stage continuous operation from 8 h with a dilution rate of 0.029/h (D1), HA was produced in the range of 7.5-10 g/l. During the 2nd stage from 44 h with a dilution rate of 0.036/h (D2), HA production (8.28 g/l) was initially reduced to a small extent due to increase of dilution rate from D1 to D2, and then a new pseudo-steady state was formed within a few hours with a concurrent small variations of HA production. The HA amount produced during the latter part of the 2nd stage was stably maintained in the range of 8.28-9.48 g/l, about 4.7% less amount compared to the 1st stage. Due to 24% increase of dilution rate from D1 to D2, however, maximum volumetric productivity (DP) amounting to 0.341 g/l/h was obtained at 96 h during the 2nd stage. This maximum productivity obtained from the continuous culture turned out only a small increase (3%) as compared to the corresponding batch fermentation. However, it should be noted that, in the case of batch process, one run typically consists of serial stages of growth culture plus one final production culture. This implies that, if the continuous fermentation that practically needs no dead time necessary for the multi-stage growth cultures is run for longer period, the total amount of the accumulated HA would be far greater than the amount obtained from the corresponding batch culture performed for the identical period.