• Tuberculosis and Respiratory Diseases
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• v.57 no.1
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• pp.55-60
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• 2004

Anticonvulsant hypersensitivity syndrome (AHS) is an uncommon, but potentially fatal and mutilsystemic disorder that occurs after exposure to the arene oxide-producing anticonvulsants-carbamzepine, phenobarbital and phenytoin. The multisystemic reactions include fever, skin eruptions, lymphadenopathy, hematologic abnormality and hepatitis. The diagnosis of AHS is made by history of drug exposure and clinical course. No specific treatments are proved as benefit except discontinuing the offending drug and trying the steroids in some severe cases. We report a case of carbamazepine induced anticonvulsant hypersensitivity syndrome characterized by skin rash, eosinophilia, subcarinal lymphadenopathy and eosinophilic pneumonia. The patient was resolved completely after only discontinuing carbamazepine.

• The Transactions of the Korea Information Processing Society
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• v.4 no.2
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• pp.563-572
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• 1997

E-mail has been eidely used for unformation delivery as an Inernet serive. As multimedia etchnologies are developed rapidly, most of the recent Unternet infornation servies support multimedia data. E-mail system also needs to suport multimedia nesage. But Internet mail servise using simple maiol transfer protocol(SMTP) speci-fied in RFC 821/822 handles only ASCII text messages repressented with 7-bit code. Each line the message has the length limitation as well. Those are why it cannot satisfy the diverse user'w demands. Multipuepose Unternet mail extensions(MIMZE), which is a modification and supplement of RFC 822,was proposed for supporting transportation of multimedia data.It can solve the limitations of sizes and types in contents of a message. In this study the E-mail system has been designed and implemented according to the MIME standard in order to solve the limitations of transpotation of messages regardless of the message content type. Hypertext markup language(HTML)syntax is applied to the mail system, and so it is possible to display a message consisting of differnt media as an intergrated from for the purpose of better understanding a message. No application program is needed for displaying a message including image data,and convenience for user is considered in the system. The futuer work is to improve the E-mail system so that it may support motion pictures and sound information,Thereby tge perfor multimeda E-mail system providing inergrated user's wiew will be developed.

• Journal of the Korean Dietetic Association
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• v.23 no.3
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• pp.263-273
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• 2017

Numerous studies have investigated quantifying dietary intake according to the weight status of children and adolescents. However, studies on differences in quality among diets remain scarce. This study compared diet quality by weight status and examined correlations between quality of diet and obesity in children and adolescents. Two hundred fourteen children and adolescents aged between 9 and 18 years participated in this study (Normal weight n=104, Obesity n=110). The data related to food intake were investigated by dietary records, Diet Quality Index-International (DQI-I), and Nutrition Quotient (NQ) and then compared with Dietary Reference Intakes for Korean (KDRIs). In DQI-I, moderation factor (control of unhealthy foods) score was 21.7 in the normal weight group and 19.5 in the obesity group. The normal weight group showed a higher score for moderation factor than the obesity group (P<0.001). Compared with KDRIs, vitamin $B_6$, folate, vitamin C, vitamin E, calcium, potassium, and zinc intakes were insufficient in both groups. Multiple logistic regression analysis revealed that DQI-I moderation was negatively associated with obesity (OR=0.77, 95% CI 0.69-0.87) after adjustment for age, gender, income, and total energy intake. Our results suggest that children and adolescents require nutritional education to understand the importance of vitamin and mineral consumption. Especially, education for children and adolescents with obesity needs to emphasize moderation of nutrient intake that can cause diseases with hyper-ingestion such as sodium and high calorie-low nutrition foods.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.34 no.5
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• pp.525-534
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• 2016

In South Korea, paddy rice has been consumed over the entire region and it is the main source of income for farmers, thus mathematical model for the estimation of rice yield is required for such decision-making processes in agriculture. The objectives of our study are to: (1) develop rice yield estimation model using Convolutional Neural Networks(CNN), (2) choose hyper-parameters for the model which show the best performance and (3) investigate whether CNN model can effectively predict the rice yield by the comparison with the model using Artificial Neural Networks(ANN). Weather and MODIS(The MOderate Resolution Imaging Spectroradiometer) products from April to September in year 2000~2013 were used for the rice yield estimation models and cross-validation was implemented for the accuracy assessment. The CNN and ANN models showed Root Mean Square Error(RMSE) of 36.10kg/10a, 48.61kg/10a based on rice points, respectively and 31.30kg/10a, 39.31kg/10a based on 'Si-Gun-Gu' districts, respectively. The CNN models outperformed ANN models and its possibility of application for the field of rice yield estimation in South Korea was proved.

• Molecules and Cells
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• v.37 no.11
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• pp.833-840
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• 2014

Cullin4-RING ubiquitin ligase (CRL4) is a family of multi-subunit E3 ligases. To investigate the possible involvement of CRL4 in heat stress response, we screened T-DNA insertion mutants of putative CRL4 substrate receptors that exhibited altered patterns in response to heat stress. One of the mutants exhibited heat stress tolerance and was named heat stress tolerant DWD1 (htd1). Introduction of HTD1 gene into htd1-1 led to recovery of heat sensitivity to the wild type level, confirming that the decrease of HTD1 transcripts resulted in heat tolerance. Therefore, HTD1 plays a negative role in thermotolerance in Arabidopsis. Additionally, HTD1 directly interacted with DDB1a in yeast two-hybrid assays and associated with DDB1b in vivo, supporting that it could be a part of a CRL4 complex. Various heat-inducible genes such as HSP14.7, HSP21, At2g03020 and WRKY28 were hyper-induced in htd1-1, indicating that HTD1 could function as a negative regulator for the expression of such genes and that these genes might contribute to thermotolerance of htd1-1, at least in part. HTD1 was associated with HSP90-1, a crucial regulator of thermotolerance, in vivo, even though the decrease of HTD1 did not affect the accumulation pattern of HSP90-1 in Arabidopsis. These findings indicate that a negative role of HTD1 in thermotolerance might be achieved through its association with HSP90-1, possibly by disturbing the action of HSP90-1, not by the degradation of HSP90-1. This study will serve as an important step toward understanding of the functional connection between CRL4-mediated processes and plant heat stress signaling.

• Science of Emotion and Sensibility
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• v.20 no.4
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• pp.89-100
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• 2017

Since smart devices are able to efficiently provide information without barriers of time and location, they are widely utilized with advent of the hyper-connected society. Especially, the smart devices have been developed in the form of wearable devices for mutual interaction between human and objects. Smart clothing, which embeds smart devices within clothes, measures and obtains a variety of bio-signals as it is in close contact with the human bodies. Conventional smart clothing generated wearers' discomfort because they were developed by simple attachment of electronic devices to clothes. Therefore, it is highly recommended to develop novel smart clothing based on smart textiles which integrate electronic devices as parts of textiles. As smart watches are currently the most available wearable devices in the market, smart watch users were selected in this study, for the purpose of investigating core needs of wearable smart device users based on the user experience and user's sensibility. Qualitative research was performed through semi-structured interview in order to obtain detailed answers about user sensibility based on smart watch user experience. After the in-depth interview, the user's sensibility was categorized into four aspects; functional, aesthetic, social, and empirical. Sensibility adjectives and key words were assigned to each aspect and their frequency was analyzed. It was the functional aspect of sensibility that the wearable device users require the most. The results of this study will be utilized as a fundamental data to develop the smart textiles required for the next generation of smart clothing which is attracting as a future wearable device.

• Archives of design research
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• v.17 no.3
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• pp.413-420
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• 2004

New design method has been required for web designers to grasp the proper emotion, impression, and feeling of a web site and reflect these elements in web design. It is certain that such a new methodology can be a useful design tool, although web designers have only relied on their intuition and experience to induce users to perceive specific emotion of web sites. In this study, Kansei Engineering Type Ⅰ (Nagamachi, 2002 and Park, 2000) method was applied to develop the methodology. One hundred thirty six web sites believed to convey emotions effectively were first selected by recommendation of professional web designers and twenty two web sites were finally chosen and evaluated using questionnaire. The web sites were then objectively and quantitatively assessed by measuring the degree of utilization of the design elements, balance, overall density, and homogeneity. We examined the cause-and-effect between the results of emotional and quantitative analysis by multiple regression and introduced the design methodology based on the examination. The research method and procedures applied to this study would be applicable to design studies related to the emotional inducement.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.8
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• pp.99-105
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• 2017

With the advancement of Information and Communication Technology (ICT), the wearable-device industry is growing at a rapid pace in line with the hyper-connected society of people-to-things and things-to-things network connections. International Data Corporation (IDC), a market research institute, estimates that the wearable-device industry will grow rapidly by 2020, despite not yet attracting a popular response. This study investigates the trend of the wearable-device industry and draws implications for product and service development through user experience analysis. The subject of analysis was smart bands and the data generated from product review were collected and analyzed. As a result, user experience could extract utility, usability, aesthetics, value, and reliability, and polarity was analysed and visualized in the extracted data. The study results reveal that current wearable-devices are expensive, that users cannot receive useful information from the long-term viewpoint since the analysis of accumulated data remains focused on functional development, and that they are recognized as a fashion item or an accessory. These factors hinder the continuous usage, motivation and market spread of the product. In a future follow-up study, we will conduct a comparative study on bands and watches by analyzing the second smart watch.

• Korean Journal of Microbiology
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• v.41 no.4
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• pp.262-268
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• 2005

Intoxication of murine macrophages (RAW 264.7) with the anthrax lethal toxin (LeTx 100 ng/ml) results in profound alterations in the host cell gene expression. The role of LeTx in mediating these effects is unknown, largely due to the difficulty in identifying and assigning function to individual proteins. In this study, we have used two-dimensional polyacrylamide gel electrophoresis to analyze the protein profile of murine macrophages treated with the LeTx, and have coupled this to protein identification using MALDI-TOF mass spectrometry. Interpretation of the peptide mass fingerprint data has relied primarily on the ProFound database. Among the differentially expressed spots, cleaved mitogen-activated protein kinase kinase (Mek1) and glucose-6-phosphate dehydrogenase were increased in the LeTx treated macrophages. Mek1 acts as a negative element in the signal transduction pathway, and G6PD plays the role for the protection of the cells from the hyper-production of active oxygen. Our results suggest that this proteomic approach is a useful tool to study protein expression in intoxicated macrophages and will contribute to the identification of a putative substrate for LeTx.

• Horticultural Science & Technology
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• v.33 no.5
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• pp.737-750
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• 2015

This study was carried out to construct a DNA profile database for 102 watermelon cultivars through the comparison of polymorphism level and genetic relatedness using genomic microsatellite (gMS) and expressed sequence tag (EST)-microsatellite (eMS) markers. Sixteen gMS and 10 eMS primers showed hyper-variability and were able to represent the genetic variation within 102 watermelon cultivars. With gMS markers, an average of 3.63 alleles per marker were detected with a polymorphism information content (PIC) value of 0.479, whereas with eMS markers, the average number of alleles per marker was 2.50 and the PIC value was 0.425, indicating that eMS detects a lower polymorphism level compared to gMS. Cluster analysis and Jaccard's genetic distance coefficients using the unweighted pair group method with arithmetic average (UPGMA) based on the gMS, eMS, and combined data sets showed that 102 commercial watermelon cultivars could be categorized into 6 to 8 major groups corresponding to phenotypic traits. Moreover, this method was sufficient to identify 78 out of 102 cultivars. Correlation analysis with Mantel tests for those clusters using 3 data sets showed high correlation ($r{\geq}0.80$). Therefore, the microsatellite markers used in this study may serve as a useful tool for germplasm evaluation, genetic purity assessment, and fingerprinting of watermelon cultivars.