• Nutritional Sciences
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• 제9권1호
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• pp.48-54
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• 2006

Methods have been developed to evaluate the total antioxidant capacity of foods and plasma but limitations are associated with their ability to determine precisely the contribution of lipophilic antioxidants in a lipid milieu as well as interactions among them Thus, we modified the Oxygen Radical Absorbance Capacity (ORAC) assay to determine the peroxyradical scavenging ability of both hydrophilic and lipophilic compartments in plasma The hydrophilic ORAC assay was performed in a phosphate buffer system utilizing 2,2'-azobis (2-amidinopropane) dihydrochloride as a peroxyradical generator and fluorescein as the target The lipophilic ORAC assay was carried out in a dimethylsulfoxide :butyronitrile (DMSO/BN, 9:1 v/v) system using 2,2'-azobis (2,4-dimethyl valeronitrile) as a peroxyradical generator and BODIPY C11 581/591 as the target Analyses were conducted in bovine serum supplemented with water - and lipid - soluble antioxidants and in human plasma. Albumin (0.5$\sim$5 g/dL) and uric acid (0.1$\sim$0.5 $\mu$mol/L) increased hydrophilic ORAC values in a dose-dependent fashion ($R^{2}$=0.97 and 0.98, respectively) but had no impact on lipophilic ORAC values. $\alpha$-Tocopherol (15$\sim$200 $\mu$mol/L) increased lipophilic ORAC values in a dose-dependent fashion ($R^{2}$=0.94); neither $\alpha$-tocopherol nor $\beta$-carotene had an impact on hydrophilic ORAC values. However, addition of $\beta$-carotene at physiological concentration (0.23$\sim$1.86 $\mu$mol/L), either alone or in combination with other carotenoids, had no significant impact on lipophilic ORAC values. Thus, while assays of 'total antioxidant capacity' in biological matrices would be a useful research and clinical tool, existing methods are limited by the lack of complete responsiveness to the full range of dietary antioxidants.

• 환경영향평가
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• 제2권2호
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• pp.73-83
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• 1993

Increasing concern for the environment in Korea has led to the demand that major policies and large-scale development projects be subjected to detailed impact assessment. This paper reports on the state of data related to the prediction of the environmental impact (EIA) to emphasize the importance of data quality. Environmental impact statements (EIS) consulted with the Ministry of Environment of Korea were analyzed from 1981 through 1992. Many of assessors used existing data and collected supplementary data from field survey. Most of the results of EIA are presented directly or summarized on maps and as graphics. For the national purpose, large source of quality-controlled data such as atmospheric data have been developed, However, there are the deficiency in data to analyze the impact of human activity, and data gaps and incompatibilities among systems. Consequently, the development of data bank systems including computer database and remotely-sensed satellite data is required to improve the quality of data which are relevant to EIA. The data bank system should be organized meaningfully in minimum time with a least cost, and measurement standards must be made explicit. Geographical information systems (GIS) are applicable to the graphic presentation or to the impact prediction model.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 추계국제학술대회
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• pp.121-123
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• 2003

The registration of a pesticide for use in the gardens or a farmer's field requires assessment of the potential negative effects of that pesticide on human health. To anticipate how a pesticide might impact human health, laboratory animals such as mice and rats are exposed to varying dosages in their foods -from very minimal to extremely high levels. Toxicologists then evaluate the observable effect(s) of consuming known quantities of that specific pesticide on acute, subchronic, chronic, mutational, reproduction and neurological effects. Information gained from such test is evaluated by toxicologists and medical experts to determine potential human effects

• Biotechnology and Bioprocess Engineering:BBE
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• 제5권5호
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• pp.307-312
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• 2000

As the first assembly of the human genome was announced on June 26, 2000, we have entered post genome era. The genome sequence represents a new starting point for science and medicine with possible impact on research across the life sciences. In this review I tried to offer brief summaries of history and progress of the Human Genome Project and two major challenges ahead, functional genomics and DNA sequence variation research.

• 대한지리학회지
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• 제33권spc호
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• pp.729-738
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• 1998

Under background of global change, regional and local environmental changes in short-term are significantly influenced by human activities in recent time. This paper deals with serious environmental problems which has become a barrier of sustainable development in the lower reach of Yellow River due to over use of diverted water from Yellow River and underground water from coastal plain. Some countermeasures for improving local environment and economic development are introduced in the paper.

• 인터넷정보학회논문지
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• 제13권5호
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• pp.9-19
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• 2012

디지털 콘텐츠에서 HCI로 활용되는 가상 인간은 얼굴 표정과 신체자세와 같은 모달을 이용하여 다양한 감정을 표현하지만 비언어적 다중모달의 조합에 대한 연구는 많지 않다. 감정을 표현하는 가상 인간을 제작하려면 계산 엔진 모델은 얼굴 표정과 신체자세와 같은 비언어적 모달의 조합이 사용자에 의해 어떻게 인식되는지를 고려해야 하기 때문에 본 연구는 가상 인간의 감정 표현 디자인에 필요한 비언어적 다중모달의 영향을 분석하여 제시한다. 먼저 가상 인간에 대한 다중모달 별 감정 인식을 평가하여 다른 모달간의 상대적 영향성을 분석하였다. 그리고 일치하는 얼굴과 자세 모달을 통해 기본 감정 및 정서가와 활성화 인식에 대한 영향을 평가하며 감정이 불일치하는 다중모달을 통해 일상생활에서 빈번하게 드러나는 중첩된 감정의 인식 정도를 관측하였다. 실험 결과, 가상 인간의 얼굴과 신체자세의 표정이 일치하면 감정 인식이 용이하며, 얼굴 표정으로 감정 카테고리를 판별하지만 감정의 활성화 차원 판단에는 자세 모달리티가 선호됨을 확인하였다. 본 연구 결과는 감정을 드러내는 가상 인간의 행동 동기화 및 애니메이션 엔진 시스템 구현에 활용할 수 있다.

• 벤처창업연구
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• 제14권3호
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• pp.39-46
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• 2019

기업의 내적 R&D 열의를 키우기 위해 외부 파트너와의 제휴가 가치 있다는 연구가 많이 진행돼 왔다. 하지만 혁신적 성과를 창출하기 위해 전략적 제휴가 가진 잠재적 역할을 활용하는 방법에 대해서는 잘 알려져 있지 않다. 본 연구는 전략적 제휴의 가치를 연구하고, 전략적 제휴의 혁신 성과에 대한 영향에 인적 자본이 어떤 역할을 하는 지를 분석한다. 본 연구는 인적 자본의 흡수역량이 전략적 제휴와의 상호작용을 통해 기업의 혁신에 끼치는 영향에 초점을 맞춘다. 2,205개의 대한민국 벤처기업을 대상으로 한 분석에서 전략적 제휴는 혁신 성과에 정의 유의한 영향을 미치는 것으로 나타났다. 하지만 전략적 제휴와 혁신 성과 간의 관계에서 인적 자본의 조절 역할은 부의 유의한 영향을 보여준다. 이것은 외부의 파트너로부터 얻은 지식과 정보를 내재화시키는 능력이 중요함을 보여준다. 본 연구는 인적자본의 상호작용을 고려함으로써 전략적 제휴의 효과성을 증진시키고자 하는 경영자에게 가치 있는 시사점을 제공한다.

• 한국전기전자재료학회논문지
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• 제37권5호
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• pp.486-493
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• 2024

Lighting has been used for a long time as a medium to convey brightness from darkness, and through incandescent lamps and fluorescent lamps, LED light sources have now become the standard in the lighting industry. Recently, the lighting equipment industry has been undergoing rapid digital transformation, starting with smart lighting, and is evolving into smart lighting customized for individuals and spaces through the development of IoT technology, cloud-based services, and data analysis. However, the blue light emitted from digital devices (computers, smartphones, tablets, etc.) or LED lights stimulates the melanopsin in the optic ganglion cells in the retina of the eye, which in turn stimulates the secretion of melatonin through the pineal gland, which regulates the secretion of melatonin. This can reduce sleep quality or disrupt biological rhythms. This interaction between blue light and melatonin has such a significant impact on human sleep patterns and overall health that it is essential to reduce exposure to blue light, especially in the evening. Human-centered lighting refers to lighting that takes into account the effects of light on the physical and mental areas, such as human activity and awakening, improvement of sleep quality, and health management. Many research institutes study the effects in the visible area and the non-visible area. By studying the impact, it is expected to improve the quality of human life. In this study, we plan to study ways to implement human-centered lighting by collecting sunrise and sunset data and linking commercialized LED packages and control devices with open-source hardware.

• International Journal of Precision Engineering and Manufacturing
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• 제6권3호
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• pp.3-7
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• 2005

This paper presents the experimental results to verify the atomization characteristics and environmental impact of cutting fluid. Even though cutting fluid improves the productivity through the cooling and lubricating effects, environmental impact due to cutting fluid usage is also increased on factory shop floor. Cutting fluid's aerosol via atomization process can generate human health risk such as lung cancer and skin diseases. Experimental results show that the generated fine aerosol of which particle size less than 10 micron appears near working zone under typical operation conditions. The aerosol concentration also exceeds NIOSH regulations. This research can be provided as a basis of environmental impact analysis for environmental consciousness.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2000년도 춘계학술대회논문집
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• pp.172-176
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• 2000

A series of preliminary experiments were carried out to quantify the annoyance are noisiness caused by floor impact noise. From the results of the experiments. the heavy impact source was found to be felt louder and noisier than the light impact source. Measurements of noise were also conducted by a diagnostic system based on the model(the model consists of the autocorrelators and the cross-correlation for signals arriving at two ear entrants) of the human auditory-brain system. Physical factors in the model were calculated by use of the ACF(autocorrelation function) and IACF(interaural cross correlation function) of binaural signals. From the ACF/IACF analysis, it was found that perceived loudness of floor impact noise could be represented by the factors of the ACF/IACF model.