• Title/Summary/Keyword: HPS

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Transcriptome profiling identifies immune response genes against porcine reproductive and respiratory syndrome virus and Haemophilus parasuis co-infection in the lungs of piglets

  • Zhang, Jing;Wang, Jing;Zhang, Xiong;Zhao, Chunping;Zhou, Sixuan;Du, Chunlin;Tan, Ya;Zhang, Yu;Shi, Kaizhi
    • Journal of Veterinary Science
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    • v.23 no.1
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    • pp.2.1-2.18
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    • 2022
  • Background: Co-infections of the porcine reproductive and respiratory syndrome virus (PRRSV) and the Haemophilus parasuis (HPS) are severe in Chinese pigs, but the immune response genes against co-infected with 2 pathogens in the lungs have not been reported. Objectives: To understand the effect of PRRSV and/or HPS infection on the genes expression associated with lung immune function. Methods: The expression of the immune-related genes was analyzed using RNA-sequencing and bioinformatics. Differentially expressed genes (DEGs) were detected and identified by quantitative real-time polymerase chain reaction (qRT-PCR), immunohistochemistry (IHC) and western blotting assays. Results: All experimental pigs showed clinical symptoms and lung lesions. RNA-seq analysis showed that 922 DEGs in co-challenged pigs were more than in the HPS group (709 DEGs) and the PRRSV group (676 DEGs). Eleven DEGs validated by qRT-PCR were consistent with the RNA sequencing results. Eleven common Kyoto Encyclopedia of Genes and Genomes pathways related to infection and immune were found in single-infected and co-challenged pigs, including autophagy, cytokine-cytokine receptor interaction, and antigen processing and presentation, involving different DEGs. A model of immune response to infection with PRRSV and HPS was predicted among the DEGs in the co-challenged pigs. Dual oxidase 1 (DUOX1) and interleukin-21 (IL21) were detected by IHC and western blot and showed significant differences between the co-challenged pigs and the controls. Conclusions: These findings elucidated the transcriptome changes in the lungs after PRRSV and/or HPS infections, providing ideas for further study to inhibit ROS production and promote pulmonary fibrosis caused by co-challenging with PRRSV and HPS.

Implementation of Quota system for efficiency using on HPSS (대용량 테이프 저장 장치의 효율적인 사용을 위한 사용량 제한시스템 구현)

  • Kim, Sung-Jun;Choi, Youn-Keun;Jang, Ji-Hoon;Kim, Joong-Kwon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2003.05b
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    • pp.911-914
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    • 2003
  • HPSS는 수 백만 개의 파일들을 동시에 처리하며 수 petabyte의 용량과 초당 수 gigabyte의 전송률을 보여주는 고성능 소프트웨어이며 고성능 컴퓨팅 환경에서 사용되는 대용량 데이터 스토리지를 위하여 개발되었다. 본 고에서는 HPSS의 대용량 테이프 저장장치 서비스를 시작하면서 사용자별로 용량 제한을 두기 위해서 사용량 제한 시스템을 구현하였다.

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A Study on Acting Forces on the Vane of Vane Pump used for Vehicles′ Hydraulic Power Steering (차량용 HPS 베인펌프의 베인의 작용력에 관한 연구)

  • 정석훈;오석형
    • Tribology and Lubricants
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    • v.20 no.3
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    • pp.163-167
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    • 2004
  • Reducing friction torque of the oil hydraulic vane pump used as the power source of power steering system should consider friction torque including viscous and mechanical friction torque according to the changes of rpm and pressure. This paper analyzes the forces acting on the vane to reduce the friction torque of the vane of the hydraulic vane pump used for Hydraulic Power Steering(HPS) system, and futhermore, the forces according to the shapes of cam profiles are analyzed.

Pyloric Stenosis in Premature Infants -Report of two cases- (미숙아에서 발생한 유문협착증 2례)

  • Park, Joong-Chae;Kim, Jeong-Nyun;Chang, Cheol-Ho;Chey, Myung-Jae;Kim, Hong-Young;Kim, Jeong-Suk;Chung, Churl-Young
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.1 no.1
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    • pp.120-124
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    • 1998
  • The incidence of Hypertrophic pyloric stenosis (HPS) in premature infants is rare, the presentation is not typical, and the diagnosis delayed due to uncertain diagnostic criteria in abdominal ultrasonography (US). We report two premature infants with HPS diagnosed by US and upper gastrointestinal (UGI) contrast study. Patient 1. A premature female infant (birth weight 1950 gm at 34 week's gestation) with the onset of intermittent vomiting at 9 days of age was evaluated. US was normal at 13 days of life, however, abnormal at 41 days of life (pyloric muscle length 16.5 mm). Patient 2. A premature male infant (birth weight 1470 gm at 29 week's gestation) with the onset of intermittent vomiting at 10 days of age was evaluated. US showed pylorospasm at 11 days of life, however, findings compatible with HPS at 57 days of life (pyloric muscle thickness 11 mm). UGI contrast study at 48 days of life showed similar findings in both cases. Both patients had undergone pyloromyotomy. In conclusion, the diagnosis of HPS in premature infants requires careful follow-up by US and UGI contrast study.

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Investigation of morphological changes of HPS membrane caused by cecropin B through scanning electron microscopy and atomic force microscopy

  • Hu, Han;Jiang, Changsheng;Zhang, Binzhou;Guo, Nan;Li, Zhonghua;Guo, Xiaozhen;Wang, Yang;Liu, Binlei;He, Qigai
    • Journal of Veterinary Science
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    • v.22 no.5
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    • pp.59.1-59.13
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    • 2021
  • Background: Antimicrobial peptides (AMPs) have been identified as promising compounds for consideration as novel antimicrobial agents. Objectives: This study analyzed the efficacy of cecropin B against Haemophilus parasuis isolates through scanning electron microscopy (SEM) and atomic force microscopy (AFM) experiments. Results: Cecropin B exhibited broad inhibition activity against 15 standard Haemophilus parasuis (HPS) strains and 5 of the clinical isolates had minimum inhibition concentrations (MICs) ranging from 2 to 16 ㎍/mL. Microelectrophoresis and hexadecane adsorption assays indicated that the more hydrophobic and the higher the isoelectric point (IEP) of the strain, the more sensitive it was to cecropin B. Through SEM, multiple blisters of various shapes and dents on the cell surface were observed. Protrusions and leakage were detected by AFM. Conclusions: Based on the results, cecropin B could inhibit HPS via a pore-forming mechanism by interacting with the cytoplasmic membrane of bacteria. Moreover, as cecropin B concentration increased, the bacteria membrane was more seriously damaged. Thus, cecropin B could be developed as an effective anti-HPS agent for use in clinical applications.

Application of plasma lighting for growth and flowering of tomato plants

  • Park, Kyoung Sub;Kim, Sung Kyeom;Lee, Sang Gyu;Lee, Hee Ju;Kwon, Joon Kook
    • Horticulture, Environment, and Biotechnology : HEB
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    • v.59 no.6
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    • pp.827-833
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    • 2018
  • Plasma lighting systems have been engineered to simulate sunlight. The objective of this study was to determine the effects of plasma lighting on tomato plant growth, photosynthetic characteristics, flowering rate, and physiological disorders. Tomato plants were grown in growth chambers at air temperatures of $25/23^{\circ}C$ (light/dark period), in a $16h\;day^{-1}$ light period provided by four different light sources: 1 kW and 700 W sulfur plasma lights (1 SPL and 0.7 SPL), 1 kW indium bromide plasma light, and 700 W high pressure sodium lamp (0.7 HPS) as a control. The totaldry weight and leaf area at 0.7 SPL were approximately 1.2 and 1.3 times greater, respectively, than that of 0.7 HPS at the 62 days after sowing (DAS). The maximum light assimilation rate was observed at 1 SPL at the 73 DAS. In addition, the light compensation and saturation points of the plants treated with plasma lighting were 98.5% higher compared with HPS. Those differences appeared to be related to more efficient light interception, provided by the SPL spectrum. The percentage of flowering at 0.7 SPL was 30.5%, which was higher than that at 0.7 HPS; however, there were some instances of severe blossom end rot. Results indicate that plasma lighting promotes tomato growth, flowering, and photosynthesis. Therefore, a plasma lighting system may be a valuable supplemental light source in a greenhouse or plant factory.

Structural complexity of the craniofacial trabecular bone in multiple myeloma assessed by fractal analysis

  • Michels, Mariane;Morais-Faria, Karina;Rivera, Cesar;Brandao, Thais Bianca;Santos-Silva, Alan Roger;Oliveira, Matheus L
    • Imaging Science in Dentistry
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    • v.52 no.1
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    • pp.33-41
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    • 2022
  • Purpose: This study aimed to evaluate the structural complexity of craniofacial trabecular bone in multiple myeloma by fractal analysis of panoramic and lateral skull radiography, and to compare the fractal dimension values of healthy patients (HPs), pre-treatment patients (PTPs), and patients during bisphosphonate treatment (DTPs). Materials and Methods: Pairs of digital panoramic and lateral skull radiographs of 84 PTPs and 72 DTPs were selected. After application of exclusion criteria, 43 panoramic and 84 lateral skull radiographs of PTPs, 56 panoramic and 72 lateral skull radiographs of DTPs, and 99 panoramic radiographs of age- and sex-matched HPs were selected. The fractal dimension values from panoramic radiographs were compared among HPs, PTPs, and DTPs and between anatomical locations within patient groups using analysis of variance with the Tukey test. Fractal dimension values from lateral skull radiographs were compared between PTPs and DTPs using the Student t-test. Pearson correlation coefficients were used to assess the relationship between the mandible from panoramic radiographs and the skull from lateral skull radiographs. Intra-examiner agreement was assessed using intraclass correlation coefficients (α=0.05). Results: The fractal dimension values were not significantly different among HPs, PTPs, and DTPs on panoramic radiographs or between PTPs and DTPs on lateral skull radiographs (P>0.05). The mandibular body presented the highest fractal dimension values (P≤0.05). The fractal dimension values of the mandible and skull in PTPs and DTPs were not correlated. Conclusion: Fractal analysis was not sensitive for distinguishing craniofacial trabecular bone complexity in multiple myeloma patients using panoramic and lateral skull radiography.

Artificial Light Sources Influence Cherry Tomato (Lycopersicon esculentum var. cv. 'CF Jelly') Growth and Development (인공광원이 방울토마토(Lycopersicon esculentum var. cv. 'CF Jelly') 생육에 미치는 영향)

  • Jeong-Wook Heo;Jeong-Hyun Baek;Young-Sin Hong
    • Korean Journal of Environmental Agriculture
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    • v.41 no.4
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    • pp.245-251
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    • 2022
  • BACKGROUND: Selection an suitable light source is essential in the year-round production of horticultural crops in closed production systems such as plant factory with controlled environments. This study was investigated to confirm the effects of artificial light sources on growth of cherry tomato'CF Jelly'(Lycopersicon esculentum var.) under high-pressure sodium lamps (HPS), metal-halide lamps (MH), and LEDs. METHODS AND RESULTS: Light intensity of the light sources was controlled at 220±30 µmol/m2/s with 12 hrs of photoperiod for a day. Flower development was significantly faster in HPS and MH treatments compared to the LEDs. There was no significant difference between the leaf number and leaf shape under the HPS and MH treatments. Reproductive growth of cherry tomato was significantly promoted by the LEDs treatment of blue plus red lights. Fruit yield per plant also increased under the LEDs compared to the others. CONCLUSION(S): Growth, flowering, and fruit setting of the cherry tomato were accomplished by the artificial lights under plant factory conditions. The HPS treatment showed negative effect on fruit quality in terms of blossom-end rot incidence compared to the LEDs or MH treatment. Effect of the LEDs on promotion of fruit weight and yield was also proved. Additional research should be carried out for improving sugar metabolism or decreasing disease in the fruits under plant factory system using only artificial lights.

Knowledge and Perceptions of the End of Life among Tunisian Medical and Paramedical Staff

  • Nayssem Khessairi;Dhouha Bacha;Rania Aouadi;Rym Ennaifer;Ahlem Lahmar;Sana Ben Slama
    • Journal of Hospice and Palliative Care
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    • v.27 no.2
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    • pp.64-76
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    • 2024
  • Purpose: End-of-life (EOL) care is a vulnerable period in an individual's life. Healthcare professionals (HPs) strive to balance the preservation of human life with respect for the patient's wishes. The aims of our study were to assess HPs' knowledge and perceptions of EOL care and to propose areas of improvement to improve the quality of care. Methods: We conducted a single-center, cross-sectional study involving HPs from a university hospital who encountered EOL care situations. We used a questionnaire divided into four sections: knowledge, practice, perception, and training. We calculated the rate of correct answers and the collective competence index. Results: Eighty-six questionnaires were analyzed, with 82.5% (71/86) completed by medical respondents and 17.5% (15/86) by paramedical respondents. Most of the respondents, 71.8% (51/71), were interns and residents. The study focused on palliative care, medical assistance in dying, aggressive medical treatment, and euthanasia, finding adequate knowledge in the first three areas. Respondents assigned to the intensive care unit and those with more than 8 years of experience had significantly higher correct answer rates than their counterparts. Seventy-five percent of respondents (65/86) reported feeling that they had little or no mastery of EOL care, primarily attributing this to insufficient training and the unavailability of trainers. Conclusion: Based on the findings of our study, which we believe to be the first of its kind in Tunisia, we can conclude that HPs possess an acceptable level of knowledge regarding EOL care. However, they require more exposure and training to develop expertise in this area.

Effect of Supplementary or Heating Lamps on the Yield, Vase Life, and Leaf Color of Cut Rose (보광등과 난방등이 절화장미 수확량, 절화수명, 엽색에 미치는 영향)

  • Jeong, Kyeong Jin;Yun, Jae Gill;Chon, Young Shin;Shin, Hyun Suk;Lee, Sang Woo
    • Journal of Bio-Environment Control
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    • v.27 no.2
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    • pp.158-165
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    • 2018
  • The effects of different kinds of supplementary lighting or heating lamps on the yield, cut flower life, and leaf color of cut rose were compared and analyzed. For this purpose, light emitting diode lamp (LED), metal halide lamps (MH), and high-pressure sodium lamps (HPS) as the supplementary lamps, and carbon fiber infrared lamp (NCFI) were installed on hydroponic cultivation bed in a cut rose farm. The yield of cut flower rose and the number of marketable flowers were greatly increased in spring and autumn by HPS treatment, but not in winter. The length of flower stalk was longer than that of control in the spring but decreased in winter. It seemed likely that the shorter flower stalk in winter was due to the shortened period of vegetative growth compared to the control because flowering was promoted by supplementary lighting. Vase life was not different among treatments in the autumn when the lighting time was short, but in winter, it was prolonged to 3 more days by only HPS, compared with the control. Leaf color was significantly affected by light treatment in winter rather than autumn. Leaf color was darkened in all supplementary lamps (LED, MH, HPS) treatment, whereas NCFI was similar to the control in leaf color. In conclusion, HPS is considered to be a very good supplementary lamp because it increases the length of flower stalk and the yield and prolongs vase life in cut roses. Even though NCFI could function as a heating lamp radiating a lot of heat, it was considered that the role as a supplementary light is unsatisfactory because the number of marketable flowers decreases and the quality index of cut rose deteriorates by NCFI.