• Title/Summary/Keyword: HEC-1

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The Effects of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) on Proliferation of MCF-7 and Hec-1B Cell Lines

  • Ryu, Y.H.;Seo, D.S.;Ko, Y.
    • Proceedings of the KSAR Conference
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    • 2003.06a
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    • pp.94-94
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    • 2003
  • Endocrine disrupters (EDs) are exogenous chemicals that interfere with the production, releasing, metabolism, excretion, binding of natural hormones, and whole endocrine systems. EDs are very dangerous since they are extremely stable, not easily degraded, and accumulated in fat and tissue. 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is known as the most toxic EDs. Therefore, this study was conducted to investigate the effects of TCDD on proliferation of human breast cancer (MCF-7) and endometrial adenocarcinoma (Hec-1B) cells. 10, 100, and 1000 nM of TCDD were treated with steroid free condition. Viable cell counting, MTT, and BrdU assay was performed to investigate cell proliferation. Apoptosis was investigated using DNA laddering. Although, DNA fragmentation as the evidence of apoptosis was not detected, all of these cell lines showed restricted proliferation at 48 hrs after 100 and 1000 nM TCDD treatments. Recently, it has been reported that the expression of transforming growth factor $\beta$s (TGF-$\beta$s) are increased in TCDD treatment and also involved in regulation of cell cycle. Therefore, these results were considered that the decreased cell prolifcration by TCDD is related to the expression of TGF-$\beta$s.

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The Analysis of Channel Junction flow Nam-Han River to the 2-Dimension (2차원 수치모형에 의한 남한강 합류흐름 해석)

  • Choi, Gye Woon;Kim, Gee Hyoung;Cho, Jun Bum;Han, Hyun Jun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2004.05b
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    • pp.589-594
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    • 2004
  • 현재까지 하천흐름의 동수역학적 해석을 위해 여러 가지 수치기법들에 대한 연구가 진행되고 발전되어져 왔다. 현재 국내에서는 주로 1차원 점변부정류 해석프로그램인 HEC-RAS 모형을 많이 사용하고 있으며, 대부분의 하천정비 기본계획 수립에 있어서도 1차원 해석모형을 적용하고 있다. 하지만 단순 하천이 아닌 합류부를 가진 하천이나 교량, 보 등의 다양한 수공구조물이 존재하는 경우 보다 정교한 흐름해석을 하기 위해 2차원 해석모형의 적용이 필요하다. 본 연구에서는 강원도 영월지역의 동강과 서강이 합쳐지는 합류부와 그 하류에 대한 영향을 알아보기 위하여 1차원 수치해석 모형인 HEC-RAS의 결과를 이용하여 2차원 수치해석 모형인 SMS의 RMA2 모델의 매개변수를 산정하였다. 2차원 수치모형을 이용하여 본 검토 유역의 빈도별 홍수량을 50년 빈도, 80년 빈도, 150년 빈도로 변화시키면서 대상구역의 유속변화를 검토하였다. 그 결과 합류부 지역에서 동강과 서강의 흐름이 충돌하면서 사수부가 발생하였고 유량이 많아질수록 그 사수부가 작아지는 경향을 보였다. 이를 바탕으로 앞으로 더 많은 CASE의 유량 및 하류수위를 변화시켜 수치모의를 하고 대상구역 내 구조물 설치 시 합류부의 유속 및 수위변화를 수치모의하여 모형실험 실시 시 예측 및 검토자료로서 활용할 것이다.

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Construction of Flood Routing Model in Milyang River using HEC-RAS Model (HEC-RAS 모형을 이용한 밀양강 홍수추적모형 구축)

  • Kim, Sang Ho;Kim, Ji Sung;Kim, Won;Choi, Kyu Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.340-340
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    • 2015
  • 기상이변에 따른 강우강도의 증가는 국지성 집중호우로 나타나게 되고, 이러한 강우양상은 하천에서의 홍수위 증가로 나타나 여러 가지 하천재해가 발생하게 된다. 본 연구에서는 대하천으로 유입되는 지류 합류부에서의 수리학적 특성을 살펴보기 위한 사전 연구로 비교적 규모가 큰 지류하천에 대한 부정류 모의를 수행할 수 있는 홍수추적모형을 구축하였다. 대상 하천은 지류 내 하도가 루프의 형태를 띠고 있는 밀양강을 대상으로 선정하였다. 낙동강의 제1지류인 밀양강에서 낙동강 합류부로부터 30.74 km 상류에 위치한 밀양강의 상동수위관측소를 상류단으로 선정하고 낙동강과 합류하는 밀양강 하류단을 대상구간으로 선정하였다. 상류 경계단인 상동수위관측소에서 측정된 수위자료는 유량자료로 환산하여 상류단 경계조건으로 사용하였으며, 하류단 경계조건은 낙동강 본류의 수산교 수위관측소와 삼랑진 수위관측소에서 측정된 수위자료를 밀양강 합류부까지의 거리 보정을 통해 밀양강 하류단의 수위자료로 사용하였다. 그림 1은 밀양강의 상동수위관측소에서부터 낙동강 합류부까지 구간에 대한 모식도를 나타내고 있으며, 그림 2는 밀양1 지점에 대한 모의결과를 나타내고 있다. 단장천 유입 이후 밀양강 본류가 두 개의 루프형으로 분류되었다가 다시 합류하는 하도의 형태를 가지고 있어 보다 복잡한 검증과정이 요구되었다. 본 연구에서 구축된 밀양강에 대한 수리학적 해석모형은 지류 합류부에서의 배수영향에 의한 수리특성을 분석하는데 활용될 것이다.

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Analysis of Hydrological Impact for Long-Term Land Cover Change Using the WMS HEC-1 Model in the Upstream Watershed of Pyeongtaek Gauging Station of Anseong-cheon (WMS HEC-1을 이용한 안성천 평택수위관측소 상류유역의 수문 경년변화 분석)

  • Kim, Seong-Joon;Park, Geun-Ae;Jung, In-Kyun;Kwon, Hyung-Joong
    • Journal of Korea Water Resources Association
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    • v.36 no.4
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    • pp.609-621
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    • 2003
  • The purpose of this study is to evaluate the hydrological impact due to temporal land cover change by gradual urbanization of upstream watershed of Pyeongtaek gauging station of Anseong -cheon. WMS HEC-1 was adopted, and DEM with 200$\times$200m resolution and hydrologic soil group from 1:50,000 soil map were prepared. Land covers of 1986, 1990, 1994 and 1999 Landsat TM images were classified by maximum likelihood method. The watershed showed a trend that forest & paddy areas decreased and urban/residential area gradually increased for the period of 14 years. The model was calibrated at 2 locations (Pyeongtaek and Gongdo) by comparing observed with simulated discharge results for 5 summer storm events from 1998 to 2001. The watershed average CN values varied from 61.7 to 62.3 for the 4 selected years. To identify the impact of streamflow by temporal area change of a target land use, a simple evaluation method that the CN values of areas except the target land use are unified as one representative CN value was suggested. By applying the method, watershed average CN value was affected in the order of paddy, forest and urban/residential, respectively.

Sediment Properties and Long-term Bed Change of Munsancheon (문산천의 유사특성 및 장기하상변동 예측)

  • Lee, Jae-Geun;Ahn, Jae-Hyun
    • Journal of Wetlands Research
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    • v.13 no.2
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    • pp.329-341
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    • 2011
  • This study was conducted with the national river, Munsancheon, which is located in Paju-si, Gyeonggi-do. The sediment discharge of Munsancheon was directly measured to analyze the sediment characteristics, and the results were used in the numerical model to predict the long-term river bed variation. The flow-total sediment discharge relation was derived using the measured total sediment discharge, and the results were compared with the total sediment discharge that was calculated using the existing prediction formula to derive a proper sediment discharge prediction method. In the actual measurements, the total annual sediment discharge was 5,478 ton/year, and the specific sediment discharge was 29.23 ton/$km^2$/year. The Ackers & White formula resulted in the values very close to the actual measurements. With the actual sediment discharge, geographical and hydrologic data as the input variables, HEC-6 and GSTARS models were comparatively analyzed. The test results showed that the HEC-6 model is suitable for the reliable prediction of the long-term river bed variation. Accordingly, the model was used for the long-term river bed variation prediction in this study. In the case of Munsancheon, deposition was continued in the downstream area and erosion occurred in the upstream area on the whole. It was expected that the stream would be stabilized in the river bed condition of 20 years later. The river bed variation was within 1 m, which was at the significance level. In the downstream area that is influenced by tide, however, the accumulation was continuously increasing within the section 2,000-7,000 m from the outlet. It seems that this should be considered in establishing the river management plans.

Analysis of Time-Area Curve Effects on Watershed Runoff (시간-면적곡선의 유역유출해석 영향분석)

  • Jeong, Dae-Myoung;Bae, Deg-Hyo
    • Journal of Korea Water Resources Association
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    • v.36 no.2
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    • pp.211-221
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    • 2003
  • The objectives of this study are to analyze the effects of time-area curve on Clark's watershed runoff method in addition to propose a GIS-based objective method for creating time-area curve. For the relative comparison of the variation of time-area curve to those of travel time and storage coefficient of Clark method, runoff sensitivities are performed on Soyang- and Chungju-dam watersheds for 1990. 9. 10~9. 14 event. The dimensionless time-area curve in HEC-1 that can be utilized in the case that the curve is not supplied is also tested in this study. The important results obtained in this study are as follows: The effects of time-area curve created by either GIS-based objective method or dimensionless curve are not significant for runoff analysis; The storage coefficient (K) and travel time( t$_{c}$), Clark's other two model parameters, are more sensitive than time-area curve for peak flow simulation. Therefore, it can be concluded that the parameters K and t$_{c}$ are more carefully estimated rather than time-area curve, when Clark method is used for runoff analysis.

A Study on the Effective Operating System for Water Supply of Andong Dam Considering the Flow of Nak-dong River (낙동강하류 유황을 고려한 안동댐의 효율적인 용수공급방안에 관한 연구)

  • Lee, Che-Chan;Jang, Suk-Hwan;Lee, Chang-Hae
    • Journal of the Korean Society of Hazard Mitigation
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    • v.8 no.6
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    • pp.129-136
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    • 2008
  • The purpose of this study is to find an effective operating system for water supply of Andong Dam. The reliability of water supply was assessed by HEC-5 model based on operated water supply data of Andong Dam and data of Jin-dong water level gauge station in Nak- dong river. In addition, estimated additional amount of water supply was evaluated for each alternative by additional retention of Andong Dam in rainy season from June to September. As the result, additional amount of water supply of each alternative in non-rainy season (excluding rainy season) is increased as $1.35m^3/s{\sim}2.12m^3/s$, it shows that additional amount of water supply can be made by effective operating system for water supply in every dam as Andang Dam.

A Study on Channel Flood Routing Using Nonlinear Regression Equation for the Travel Time (비선형 유하시간 곡선식을 이용한 하도 홍수추적에 관한 연구)

  • Kim, Sang Ho;Lee, Chang Hee
    • Journal of Wetlands Research
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    • v.18 no.2
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    • pp.148-153
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    • 2016
  • Hydraulic and hydrological flood routing methods are commonly used to analyze temporal and spatial flood influences of flood wave through a river reach. Hydrological flood routing method has relatively more simple and reasonable performance accuracy compared to the hydraulic method. Storage constant used in Muskingum method widely applied in hydrological flood routing is very similar to the travel time. Focusing on this point, in this study, we estimate the travel time from HEC-RAS results to estimate storage constant, and develop a non-linear regression equation for the travel time using reach length, channel slope, and discharge. The estimated flow by Muskingum model with storage constant of nonlinear equation is compared with the flow calculated by applying the HEC-RAS 1-D unsteady flow simulation. In addition, this study examines the effect on the weighting factor changes and interval reach divisions; peak discharge increases with the bigger weighting factor, and RMSE decreases with the fragmented division.

Simulation of Improvement Method for Narrow Cross-Section in Hyungsan River Using HEC-6 (HEC-6를 이용한 형산강 협착부 개선방안 모의)

  • Kim, Jung-Min;Kim, Young-Do;Lyu, Si-Wan;Lee, Nam-Joo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.953-957
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    • 2008
  • 일반적으로 하천은 오랫동안 장기간의 변화를 겪으며 안정되어 있다. 산사태나 홍수 등 자연적인 변화뿐 아니라 댐이나 교량 등 인위적인 변화에 따라 흐름이나 유사량이 변하게 되며 이런 동적변형상태를 복원하는 과정에서 침식과 퇴적이 반복적으로 이루어져 대규모 하상변동이 이루어지게 된다. 이러한 하천에서 발생하는 대규모의 하상변동에는 일반적으로 1차원 해석이 적용된다. 하천의 일정 하도구간을 고려할 경우 구간의 상류단면으로부터 유입하는 유입토사량과 하류단면에서 유출되는 유출토사량과의 비에 따라 그 구간에는 하상상승(aggradation)및 하상저하(degradation)가 발생하게 되고 이것이 거시적 측면에서 하상변동이라 할 수 있다. 이러한 장기하상변동은 경우에 따라서 이수용도의 수문 혹은 취수구가 노출되거나, 교량의 교각에 국부세굴이 발생되어 붕괴위험이 생기는 등 심각한 문제가 발생할 수가 있다. 본 연구에서는 하상변동 예측 모형 중 신뢰성 및 적용성이 우수한 것으로 인식되고 있는 HEC-6 모형을 형산강수계에 적용하여 4가지 협착부 개선방안에 따른 장기하상변동에의 영향을 검토하고자 하였다. 하천기본계획상의 횡단면도와 유사량 실측값을 이용하여 유사모의 결과를 검증하고 2020년까지의 모형의 계산 값을 이용하여 4가지 대안에 따른 모의 결과와 원안의 결과와 비교 및 분석하였다. 모의한 결과 형산강의 하상변동치가 크지 않은 것은 형산강의 하상이 어느 정도 안정되어 있어 장기적인 하상변동이 크지 않기 때문이다. 따라서 협착부 개선에 따른 대안 1, 2, 3, 4의 하상이 크게 변하지 않음을 보였다. 지형 변화에 따른 장기하상변동에의 영향이 크지 않은 것을 확인할 수 있다.

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The Study of Flood Simulations using LiDAR Data (LiDAR 자료를 이용한 홍수 시뮬레이션에 관한 연구)

  • Shim, Jung-Min;Lee, Suk-Bae
    • Journal of Korean Society for Geospatial Information Science
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    • v.14 no.4 s.38
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    • pp.53-60
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    • 2006
  • The purpose of this paper is forcasting of flooding area using LiDAR surveying data, and flood map for damage prevention is established for this purpose. Teahwa river at Ulsan city was chosen as test area and the flood simulation was produced in this area. For the flood simulation, each DEM using LiDAR data and digital map was established and then HEC model program and MIKE program was used to decide the amount of flood flowing and flood height. To improve the rainfall-overflow simulation confidence using inspection comparison of LiDAR data this paper analyzed and compared the LiDAR DEM accuracy and 1/5000 digital map DEM. The height accuracy is important factor to make flood map, however, LiDAR survey execution of all river area is not economic so, LiDAR survey execution of only important area is possible to be make high accuracy and economic flood map. The expectation effect of flood simulation is flood damage prevention and economic savings of recovery cost by forcasting of rainfall-overflow area and establishment of counter-measure.

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