• 제목/요약/키워드: HARM

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의료기기 시스템의 해저드 분석 기법 비교 (Comparison of Hazard Analysis for Medical Device System)

  • 최보윤;이병걸;한혁수
    • 인터넷정보학회논문지
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    • 제19권6호
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    • pp.133-145
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    • 2018
  • 의료기기 분야의 시스템들은 사고가 발생할 경우 상해 등의 큰 피해를 줄 수 있으므로 사고가 발생할 수 있는 원인을 찾아 사고를 예방하고 피해를 최소화하는 해저드 분석 활동이 필수적이다. 해저드 분석 활동은 분석 목적에 따라 수행 방법이 다르고 적용할 수 있는 개발 단계가 다르기 때문에 분석 대상 시스템에 적합한 기법을 선택하는 것은 매우 어려운 일이다. 개발 단계 중 개념 단계에서 식별된 해저드를 기반으로 해저드를 완화하거나 예방하기 위한 기본 안전 요구사항이 도출되기 때문에 개념 단계에서 적합한 해저드 기법을 선택하는 것은 매우 중요하다. 본 논문에서는 의료기기 분야 시스템들의 해저드 분석 활동에 적합한 기법을 선택할 수 있도록 개발 단계 중 개념 단계에서 PHA 기법과 STPA 기법을 비교하도록 한다. 이 분석을 통해 의료기기 시스템에서 개념 단계의 적합한 해저드 분석 기법을 선정할 수 있을 것이다.

외상후 스트레스장애에서 기질 및 성격의 변화 (Change of Temperament and Personality in Post-traumatic Stress Disorders)

  • 최효선;김대호;김은경
    • 정신신체의학
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    • 제28권2호
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    • pp.155-160
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    • 2020
  • 연구목적 본 연구는 외상후 스트레스장애(Posttraumatic Stress Disorder, PTSD)를 비롯한 정신질환자의 기질과 성격의 변화 양상을 확인하고 한다 방 법 PTSD 환자 33명과 비PTSD 환자 69명을 대상으로 Temperament and Character Inventory (TCI)를 1, 2차에 걸쳐 측정하였고, 그 결과값에 대해 반복측정 ANOVA와 단순 주효과분석을 시행하였다. 결 과 비PTSD 집단에서는 1차와 2차 검사 결과의 차이가 나타나지 않았다. 반면, PTSD 집단에서는 위험회피, 사회적 민감성, 자율성, 연대감에서 유의미한 차이가 있었다. 또한 위험회피, 사회적 민감성, 자율성, 연대감에서 시간과 그룹 간의 상호작용과 시간에 따른 주효과가 유의하게 나타났다. 결 론 본 연구는 외상적 사건이 자율성, 연대감과 같은 성격적 특성은 물론, 위험회피와 사회적 민감성과 같은 기질적 특성의 변화에 영향을 미칠 수 있음을 확인하였다는 점에서 의의가 있다.

손소독제 사용 실태 조사 및 성분 분석 (Survey on the Use of Hand Sanitizer and Component Analysis)

  • 윤혜경;이은지;허예림;박나연;고영림
    • 한국환경보건학회지
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    • 제46권6호
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    • pp.702-709
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    • 2020
  • Objectives: Hand sanitizer is made with ethyl alcohol as the main ingredient. Problems related to the use of hand sanitizers and cases of harm caused by the use of hand sanitizers are occurring. This study investigated the usage behavior and recognition level of people using hand sanitizer and identified the chemical components listed in the component label of hand sanitizer. In addition, the methanol and isopropanol contained in hand sanitizer were quantified using HS-GC-MSD. Methods: The investigation of the behavior and recognition of hand sanitizer usage was conducted through a survey of 143 college students and adults. The components marked on 34 types of hand sanitizers were investigated, and methanol and isopropanol concentrations were analyzed using the HS-GC-MSD method. Results: According to the survey, 57% of respondents use hand sanitizers two to three times per day, 92.3% of them do so when in public places and 41.3% of them do so at home. Ethanol, purified water, carbomer, glycerin, and triethanolamine were the ingredients listed in the hand sanitizer. Among the 34 samples, methanol and isopropyl alcohol were detected in 33 samples, the concentration range for methanol was ND-567 ppm, and the concentration range of isopropyl alcohol was ND-2121 ppm. Conclusion: The results of this study have shown that hand sanitizers are being used constantly every day, and methanol, which is not included in the marked content, was detected in a significant concentration compared to wet tissue. It has been found that maintenance of hand sanitizer manufacturing standards and training on how to use them are needed.

IoT 장치에서 메모리 용량 제한을 고려한 멀티미디어 콘텐츠 설계 기법 (A Design Scheme for Multimedia Contents Considering Memory Constraints in IoT Devices)

  • 손경아
    • 한국정보통신학회논문지
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    • 제24권11호
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    • pp.1463-1469
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    • 2020
  • 동영상이나 음성을 포함하는 멀티미디어 정보는 사람들이 쉽게 이해 가능하다는 점에서 활용도가 높다. 이러한 이유로 멀티미디어 정보를 저장한 IoT 장치가 스마트폰과 연동하여 정보를 전달하는 응용들이 연구되었다. 문제는 동영상이나 이미지 등으로 인해 정보의 크기가 IoT장치의 용량보다 커질 수 있다는 것이다. 본 논문에서는 IoT 장치처럼 저장용량에 한계가 있는 경우, 저장 용량의 한계를 고려한 멀티미디어 콘텐츠 설계 기법을 연구하였다. 동영상이 문자보다 정보 이해도가 높은 반면 용량은 크다는 점을 고려하여 정보 이해도와 용량 간의 해법을 구하는 것이다. 정적미디어와 동적미디어의 크기를 변수로 하고 선형 계획법에 의거하여 해를 풀이한다. 사례 연구를 통하여 본 논문의 설계기법이 유용함을 보였다.

유기물 농도가 낮은 고품질 정수 생산을 위한 고압막여과 공정 설계 시 고려사항 (Considerations to design high-pressure membrane system to produce high quality potable water with lower organic matter concentration)

  • 전종민;김성수;서인석;김수한
    • 상하수도학회지
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    • 제34권6호
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    • pp.473-480
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    • 2020
  • High-pressure membrane system like nanofiltration(NF) and reverse osmosis(RO) was investigated as a part of water treatment processes to produce high quality potable water with low organic matter concentration through membrane module tests and design simulation. River water and sand filtration permeate in Busan D water treatment plant were selected as feed water, and NE4040-90 and RE4040-Fen(Toray Chemical Korea) were used as NF and RO membranes, respectively. Total organic carbon(TOC) concentrations of NF and RO permeates were mostly below 0.5 mg/l and the average TOC removal rates of NF and RO membranes were 93.99% and 94.28%, respectively, which means NF used in this study is competitive with RO in terms of organic matter removal ability. Different from ions rejection tendency, the TOC removal rate increases at higher recovery rates, which is because the portion of higher molecular weight materials in the concentrated raw water with increasing recovery rate increases. Discharge of NF/RO concentrates to rivers may not be acceptable because the increased TDS concentration of the concentrates can harm the river eco-system. Thus, the idea of using NF/RO concentrate as the raw water for industrial water production was introduced. The design simulation results with feed water and membranes used in this work reveal that the raw water guideline can be satisfied if the recovery rate of NF/RO system is designed below 80%.

Difference of Gall Formation Rates and Parasitic Rates of Thecodiplosis japonensis (Diptera: Ceidomyiidae) Larvae in Pine Forests around Urban and Mountain Villages

  • Kim, Jongkyung;Ha, Manleung;Lee, Sanggon;Kim, Hyun;Lee, Chongkyu
    • Journal of Forest and Environmental Science
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    • 제36권4호
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    • pp.290-297
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    • 2020
  • This study analyzed and compared the damage rate, natural parasitic rate, and the morphological characteristics of Thecodiplosis japonensis larvae, which inhabit forest areas as control areas to large urban areas in 2018 and 2019. This research was conducted to provide basic data for the management of Thecodiplosis japonensis, which harm pine needles, and the results were as follows. First, the gall formation rate of Thecodiplosis japonensis collected from urban areas was upper-crown 35.59% and 34.25%, mid-crown 25.57% and 27.95%, and lower-crown 25.34% and 26.61%; the gall formation rate of Thecodiplosis japonensis was in the order of upper-crown>mid-crown>lower-crown in 2018 and 2019, respectively. In the control areas, the gall formation rates of Thecodiplosis japonensis in mountain villages in 2018 and 2019 were upper-crown 17.72% and 21.78%, mid-crown 13.85% and 16.97%, and lower-crown 15.12% and 15.79%; thus, in the order of upper-crown>lower-crown>mid-crown. The number of larvae in the galls of needles damaged by Thecodiplosis japonensis was as follows: the average number of larvae in the pine trees of urban areas was 9 and 8 in the upper-crown, 7 and 8 in the mid-crown, and 6 and 7 in the lower-crown respectively. This shows that the number of larvae was fewer in the lower-crown than the upper-crown, and that the number of larvae was higher in 2018 than in 2019. For natural parasitic rate of Thecodiplosis japonensis, the gall formation rate and natural parasitic rate of Thecodiplosis japonensis were surveyed; the natural parasitic rate was 12.5% and 11.8% in urban areas while the rate was 21.7% and 20.9% in mountain villages in respectively in 2018 and 2019.

남편의 가사노동과 자녀돌봄 분담 유형별 관련요인 및 부부의 가사분담만족도: 맞벌이 부부와 비맞벌이 부부 비교 (How satisfied are they with husbands' sharing of domestic labor? Comparing couples from single-earner and dual-earner households)

  • 김소영
    • 한국가족관계학회지
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    • 제22권3호
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    • pp.47-72
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    • 2017
  • Objectives: Do husbands with working wives share domestic labor more equally than husbands with unemployed housewives? Is the husband's contribution sufficient enough to satisfy his wife? These questions have long inspired many researchers to find ways to more accurately estimate husband's domestic contributions and narrow the emotional gap following the different threshold of satisfaction within couples, but not without some limits. This study attempted to figure out an answer to the above-mentioned subject by using time diaries of Korean married couples with a preschooler as their first-born child and relying on the typology of husbands' sharing of housework and childcare, which allowed me to overcome some limitations of prior research. Method: I analyzed a total of 1,716 diaries of 858 married couples from 2014 Korea Time Use Survey with descriptive statistics, t-test, cluster analysis, and multinomial logit. Results: Analytic results showed that husbands in dual-earner households did share domestic labor more equally than husbands in single-earner households, but there were different types of husband's contribution depending on time they spent in housework and childcare. While more than half of husbands with employed wives shared more or less than ten percent of domestic labor, the rest were divided into one group of husbands who shared both housework and childcare more heavily and evenly, and another group who were mainly involved in childcare duties. It is interesting that husbands who made the least contributions to domestic labor were not the ones with the lowest level of satisfaction with their sharing of household labor, whereas their wives were deeply dissatisfied, leading to a huge emotional gap within couples. Conclusion: Identifying factors associated with the three different types allowed me to find a point of intervention to narrow the emotional gap that is likely to harm the marital relationship if left unattended to.

액상형 전자담배 용액에 의한 급성 니코틴 중독: 증례보고의 체계적 고찰 (Acute Nicotine Poisoning due to Electronic Cigarette Liquid: Systematic Review of Case Reports)

  • 양시용;좌민홍;유제성;정현수;정성필
    • 대한임상독성학회지
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    • 제18권2호
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    • pp.51-56
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    • 2020
  • Purpose: Acute nicotine poisoning by liquid nicotine in electronic cigarettes is becoming an increasing problem worldwide. The current systematic review aimed to determine the harm of acute nicotine poisoning by reviewing published case reports. Methods: An online literature search with PubMed, Embase, Cochrane Library, and KoreaMed database was performed to identify relevant studies addressing acute nicotine poisoning with electronic cigarettes. Two investigators searched the case reports written in English or Korean. Results: Twenty-six cases were included in this study. The routes of intoxication included ingestion in 18 cases, intravenous injection in three cases, subcutaneous injection in two cases, and ocular exposure in two cases. Ten cases had a cardiac arrest, and seven of them died. Seven out of 12 cases with intentional poisoning had a cardiac arrest. Nine children under 18 years were reported, and three of them had a cardiac arrest. Sixteen cases without a cardiac arrest recovered well, except for one case with sudden sensorineural hearing loss. Conclusion: The authors reviewed the risks of electronic cigarette liquid in terms of acute poisoning through a systematic review. The nicotine solution of an e-cigarette can be life-threatening in cases of acute poisoning. Therefore, active emergency treatment with early recognition is necessary. In addition, various management methods and regulations for preventing acute nicotine poisoning, such as restriction of distribution and nicotine concentration, should be considered.

Acupuncture for Symptomatic Rotator Cuff Disease: A Systematic Review and Meta-Analysis

  • Choi, Seoyoung;Lee, Jisun;Lee, Seunghoon;Yang, Gi Young;Kim, Kun Hyung
    • Journal of Acupuncture Research
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    • 제38권1호
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    • pp.20-31
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    • 2021
  • The objective was to evaluate the effectiveness and safety of acupuncture for patients with rotator cuff diseases. There were 12 electronic databases and 3 trial registries searched up to November 30th, 2019. All randomized trials were eligible, regardless of language, date of publication, or settings. The primary outcomes were pain, shoulder function, and proportion of improved participants assessed within 12 weeks of randomization of the trial. The Cochrane risk of bias for the studies was assessed. Effects sizes were presented as a risk ratio, mean difference, or standardized mean difference with a 95% confidence intervals. Grading of Recommendations Assessment, Development and Evaluation approach was adopted to rate certainty of evidence. Of the 3,686 records screened, 28 randomized trials (2,216 participants) were included in this review. The types of acupuncture included manual acupuncture, dry needling, electroacupuncture, acupotomy, warm needle acupuncture, and fire needle acupuncture. All of the studies had an unclear or high risk of bias related to more than 1 domain. Significant benefits of acupuncture in terms of pain and shoulder function were observed in all comparisons, however, the proportion of improved participants was not described in 2 comparisons. There was substantial heterogeneity among meta-analyzed trials. No serious harm was observed. For primary outcomes, the overall certainty of evidence was very low. There was very low certainty of evidence for the benefits of acupuncture for patients with rotator cuff diseases. The safety of acupuncture remains unclear due to the incompleteness of reporting. Future well-designed randomized trials with transparent reporting are required.

Short-Term Changes in Gut Microflora and Intestinal Epithelium in X-Ray Exposed Mice

  • Tsujiguchi, Takakiyo;Yamaguchi, Masaru;Yamanouchi, Kanako
    • Journal of Radiation Protection and Research
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    • 제45권4호
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    • pp.163-170
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    • 2020
  • Background: Gut microflora contributes to the nutritional metabolism of the host and to strengthen its immune system. However, if the intestinal barrier function of the living body is destroyed by radiation exposure, the intestinal bacteria harm the health of the host and cause sepsis. Therefore, this study aims to trace short-term radiation-induced changes in the mouse gut microflora-dominant bacterial genus, and analyze the degree of intestinal epithelial damage. Materials and Methods: Mice were irradiated with 0, 2, 4, 8 Gy X-rays, and the gut microflora and intestinal epithelial changes were analyzed 72 hours later. Five representative genera of Actinobacteria, Firmicutes, and Bacteroidetes were analyzed in fecal samples, and the intestine was pathologically analyzed by Hematoxylin-Eosin and Alcian blue staining. In addition, DNA fragmentation was evaluated by the TdT-mediated dUTP nick-end labeling (TUNEL) assay. Results and Discussion: The small intestine showed shortened villi and reduced number of goblet cells upon 8 Gy irradiation. The large intestine epithelium showed no significant morphological changes, but the number of goblet cells were reduced in a radiation dose-dependent manner. Moreover, the small intestinal epithelium of 8 Gy-irradiated mice showed significant DNA damaged, whereas the large intestine epithelium was damaged in a dose-dependent manner. Overall, the large intestine epithelium showed less recovery potential upon radiation exposure than the small intestinal epithelium. Analysis of the intestinal flora revealed fluctuations in lactic acid bacteria excretion after irradiation regardless of the morphological changes of intestinal epithelium. Altogether, it became clear that radiation exposure could cause an immediate change of their excretion. Conclusion: This study revealed changes in the intestinal epithelium and intestinal microbiota that may pave the way for the identification of novel biomarkers of radiation-induced gastrointestinal disorders and develop new therapeutic strategies to treat patients with acute radiation syndrome.