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http://dx.doi.org/10.5668/JEHS.2020.46.6.702

Survey on the Use of Hand Sanitizer and Component Analysis  

Yoon, Hye-Kyung (Department of Health, Environment & Safety, Eulji University)
Lee, Eun-Ji (Department of Health, Environment & Safety, Eulji University)
Hur, Ye Lim (Department of Health, Environment & Safety, Eulji University)
Park, Na-Youn (Department of Health, Environment & Safety, Eulji University)
Kho, Younglim (Department of Health, Environment & Safety, Eulji University)
Publication Information
Journal of Environmental Health Sciences / v.46, no.6, 2020 , pp. 702-709 More about this Journal
Abstract
Objectives: Hand sanitizer is made with ethyl alcohol as the main ingredient. Problems related to the use of hand sanitizers and cases of harm caused by the use of hand sanitizers are occurring. This study investigated the usage behavior and recognition level of people using hand sanitizer and identified the chemical components listed in the component label of hand sanitizer. In addition, the methanol and isopropanol contained in hand sanitizer were quantified using HS-GC-MSD. Methods: The investigation of the behavior and recognition of hand sanitizer usage was conducted through a survey of 143 college students and adults. The components marked on 34 types of hand sanitizers were investigated, and methanol and isopropanol concentrations were analyzed using the HS-GC-MSD method. Results: According to the survey, 57% of respondents use hand sanitizers two to three times per day, 92.3% of them do so when in public places and 41.3% of them do so at home. Ethanol, purified water, carbomer, glycerin, and triethanolamine were the ingredients listed in the hand sanitizer. Among the 34 samples, methanol and isopropyl alcohol were detected in 33 samples, the concentration range for methanol was ND-567 ppm, and the concentration range of isopropyl alcohol was ND-2121 ppm. Conclusion: The results of this study have shown that hand sanitizers are being used constantly every day, and methanol, which is not included in the marked content, was detected in a significant concentration compared to wet tissue. It has been found that maintenance of hand sanitizer manufacturing standards and training on how to use them are needed.
Keywords
Hand sanitizer; methanol; isopropyl alcohol; survey on the use; HS-GC-MSD;
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Times Cited By KSCI : 4  (Citation Analysis)
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1 Margaret E.K. Kraeling, Robert L. Bronaugh. In vitro absorption of triethanolamine through human skin. Journal of Toxicology: Cutaneous and Ocular Toxicology. 2003; 22(3): 137-145.   DOI
2 Ehlers A, Morris C, Krasowski MD. A rapid analysis of plasma/serum ethylene and propylene glycol by headspace gas chromatography. SpringerPlus. 2013; 203(2). 2(1): 1-6.   DOI
3 Zondlo Fiume M. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophersolan. International journal of toxicology. 2002; 21(Suppl 3): 51-116.   DOI
4 Mahmood A, Eqan M, Pervez S, Alghamdi HA, Tabinda AB, Yasar A, et al. COVID-19 and frequent use of hand sanitizers; human health and environmental hazards by exposure pathways. Sci Total Environ. 2020; 742: 140561.   DOI
5 Park JY, Kim JS, Kim JG. A study on the hand washing awareness and practices of food-service employees and the load of index microorganisms on the hands. Journal of Environmental Health Sciences. 2010; 36(2): 95-107.
6 Kim KH, Choi SC, Yoo YG, Lee SJ, Park UK, Hwang SY. Study of a hand sanitizer composed of active ingredients Geranial, Cineol, Menthol, and Chamaecyparis obtusa. Journal of Records Management & Archives Society of Korea. 2020; 16(2): 173-183.
7 Emami A, Javanmardi F, Keshavarzi A, Pirbonyeh N. Hidden threat lurking behind the alcohol sanitizers in COVID-19 outbreak. Dermatologic Therapy. 2020; 33: e13627.   DOI
8 Yip Luke, Bixler Danae, Brooks Daniel, Clarke Kevin, Datta S, Dudley S, Komatsu, et al. Serious adverse health events, including death, associated with ingesting alcohol-based hand sanitizers containing methanol. Morbidity and Mortality Weekly Report. 2020; 69(32): 1070-1073.   DOI
9 Jairoun AA, Al-Hemyari SS, Shahwan M. Scale validation for the identification of falsified hand sanitizer: public and regulatory authorities perspectives from United Arab Emirates. BMC Public Health. 2020; 20: 1595.   DOI
10 National Law Information Center. Standard manufacturing standards for quasi-drugs. Available: https://www.law.go.kr/admRulLsInfoP.do?admRulSeq=2100000116550&vSct=%EC%9D%98%EC%95%BD%EC%99%B8%ED%92%88. [accessed 11 November 2020].
11 YTN. Trying to use a hand sanitizer in the elevator... A 5-year-old kid with corneal burns. Available: https://www.ytn.co.kr/_ln/0103_202006260440269548 [accessed 09 November 2020].
12 YNA. Corona 19 disinfection house methanol spray-addicted hospital treatment. Available: https://www.yna.co.kr/view/AKR20200321050600004 [accessed 09 November 2020].
13 Food and Drug Administration. FDA updates on hand sanitizers consumers should not use. Available: https://www.fda.gov/drugs/drug-safety-andavailability/fda-updates-hand-sanitizers-consumersshould-not-use [accessed 9 November 2020].
14 Jeong MA, Mo JH, Kim SK. Components of preferred brands of anti-aging and anti-wrinkle cosmetics and satlsfaction. The Korean Society of Design Culture. 2011; 17(1): 561-573.
15 Choi YK, Baek EJ, Min CS, Lee RD, Park SY, Ahn JH, et al. Establishment for analytical method of methanol in wet wipes by headspace gas chromatography. Analytical Science and Technology. 2016; 29(5): 242-247.   DOI
16 Kim H, Lee SW, Lee JH, Han KH, Min JH, Park JS, et al. Case Reports: A case of methanol intoxication from windshield washer fluid ingestion misidentified as an alcoholic beverage. Journal of the Korean Society of Emergency Medicine. 2012; 23(5): 762-768.
17 Alnuqaydan Abdullah, Sanderson Barbara. Toxicity and genotoxicity of beauty products on human skin cells in vitro. Journal of Clinical Toxicology. 2016; 6(4): 315.
18 Kramer A, Below H, Bieber N, Kampf G, Toma CD, Huebner NO, et al. Quantity of ethanol absorption after excessive hand disinfection using three commercially available hand rubs is minimal and below toxic levels for humans. BMC infectious diseases. 2007; 7: 117.   DOI
19 Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Jr. Shank RC, et al. Safety assessment of glycerin as used in cosmetics. International Journal of Toxicology. 2019; 38(3): 6S-22S.   DOI
20 Fiume MM, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks JG, et al. Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics. International Journal of Toxicology. 2013; 32(3): 59S-83S.   DOI
21 Ahn GD, Ki YH, Ki YS, Lee SK, Lee SS, Kim HS, et al. Research on biological exposure evaluation criteria and analysis methods-17 types of organic solvents such as xylene. Korea Occupational Safety and Health Agency. 2011; 196.
22 Schneir AB, Clark RF. Death caused by ingestion of an ethanol-based hand sanitizer. The Journal of Emergency Medicine. 2013; 5(3): 358-360.   DOI
23 James B. Mowry, Daniel A. Spyker, Daniel E. Brooks, Naya McMillan, and Jay L. Schauben. 2014 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 32nd Annual Report. Clinical Toxicology. 2015; 53(10): 962-1147.   DOI
24 Chandanapalli Sai Himabindu, Bitra Tanish, Damodara Padma priya, Nimmala Prema Kumari, and Shaik Nayab. Hand sanitizers: is over usage harmful? World Journal of Current Medical and Pharmaceutical Research. 2020; 296-300.